1-(3-chlorophenyl)biguanide has been researched along with Disease Models, Animal in 9 studies
1-(3-chlorophenyl)biguanide: RN given refers to parent cp; a 5-HT3 receptor agonist
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study aims to investigate granisetron, a 5-HT( 3) receptor antagonist, in acetic acid-induced rat colitis and probable involvement of 5-HT(3) receptors." | 7.76 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| "Treatment with tropisetron and granisetron markedly suppressed the clinical symptoms of EAE (p<0." | 5.39 | Tropisetron diminishes demyelination and disease severity in an animal model of multiple sclerosis. ( Aminian, A; Dehpour, AR; Ghazi-Khansari, M; Hassanzadeh, G; Javadi, S; Kafami, L; Mehr, SE; Noorbakhsh, F; Rahimian, R, 2013) |
| "Stroke was rendered in rats by introduction of an autologous clot into the middle cerebral artery (MCA)." | 5.37 | Tropisetron ameliorates ischemic brain injury in an embolic model of stroke. ( Barzegar-Fallah, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mohammadi-Rick, S; Rahimian, R; Shabanzadeh, AP, 2011) |
| "In this regard, we used a model of clonic seizures induced by pentylenetetrazole (PTZ) in male NMRI mice to investigate whether morphine and citalopram exhibit additive anticonvulsant effects and, if so, whether this effect is mediated through modulation of 5-HT(3) receptors." | 5.37 | The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice. ( Bahremand, A; Dehpour, AR; Ebrahimi, A; Fakhfouri, G; Ghasemi, A; Ghasemi, M; Loloee, S; Payandemehr, B; Pourmand, N; Rahimian, R; Ziai, P, 2011) |
| " This study aims to investigate granisetron, a 5-HT( 3) receptor antagonist, in acetic acid-induced rat colitis and probable involvement of 5-HT(3) receptors." | 3.76 | Granisetron ameliorates acetic acid-induced colitis in rats. ( Bahremand, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mousavizadeh, K; Rahimian, R; Rasouli, MR, 2010) |
| " Smooth muscle relaxation was obtained by salbutamol and l-phenylephrine, whereas contraction was achieved by carbachol and 1-(3-chlorophenyl)-biguanide." | 3.72 | Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis. ( Garrelds, IM; Meijssen, MA; van Meeteren, ME; Zijlstra, FJ, 2003) |
| "Treatment with tropisetron and granisetron markedly suppressed the clinical symptoms of EAE (p<0." | 1.39 | Tropisetron diminishes demyelination and disease severity in an animal model of multiple sclerosis. ( Aminian, A; Dehpour, AR; Ghazi-Khansari, M; Hassanzadeh, G; Javadi, S; Kafami, L; Mehr, SE; Noorbakhsh, F; Rahimian, R, 2013) |
| "Stroke was rendered in rats by introduction of an autologous clot into the middle cerebral artery (MCA)." | 1.37 | Tropisetron ameliorates ischemic brain injury in an embolic model of stroke. ( Barzegar-Fallah, A; Daneshmand, A; Dehpour, AR; Fakhfouri, G; Mehr, SE; Mohammadi-Rick, S; Rahimian, R; Shabanzadeh, AP, 2011) |
| "In this regard, we used a model of clonic seizures induced by pentylenetetrazole (PTZ) in male NMRI mice to investigate whether morphine and citalopram exhibit additive anticonvulsant effects and, if so, whether this effect is mediated through modulation of 5-HT(3) receptors." | 1.37 | The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice. ( Bahremand, A; Dehpour, AR; Ebrahimi, A; Fakhfouri, G; Ghasemi, A; Ghasemi, M; Loloee, S; Payandemehr, B; Pourmand, N; Rahimian, R; Ziai, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Aminian, A | 1 |
| Noorbakhsh, F | 1 |
| Ghazi-Khansari, M | 1 |
| Kafami, L | 1 |
| Javadi, S | 1 |
| Hassanzadeh, G | 1 |
| Rahimian, R | 4 |
| Dehpour, AR | 4 |
| Mehr, SE | 3 |
| Ahmadi-Mahmoodabadi, N | 1 |
| Nasehi, M | 1 |
| Emam Ghoreishi, M | 1 |
| Zarrindast, MR | 1 |
| Fakhfouri, G | 3 |
| Daneshmand, A | 2 |
| Bahremand, A | 2 |
| Rasouli, MR | 1 |
| Mousavizadeh, K | 1 |
| Barzegar-Fallah, A | 1 |
| Mohammadi-Rick, S | 1 |
| Shabanzadeh, AP | 1 |
| Payandemehr, B | 1 |
| Ziai, P | 1 |
| Pourmand, N | 1 |
| Loloee, S | 1 |
| Ebrahimi, A | 1 |
| Ghasemi, A | 1 |
| Ghasemi, M | 1 |
| Zijlstra, FJ | 1 |
| van Meeteren, ME | 1 |
| Garrelds, IM | 1 |
| Meijssen, MA | 1 |
| Wada, Y | 1 |
| Shiraishi, J | 1 |
| Nakamura, M | 1 |
| Koshino, Y | 1 |
9 other studies available for 1-(3-chlorophenyl)biguanide and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Tropisetron diminishes demyelination and disease severity in an animal model of multiple sclerosis.
Topics: Animals; Biguanides; Cell Proliferation; Demyelinating Diseases; Disease Models, Animal; Dose-Respon | 2013 |
Synergistic effect between prelimbic 5-HT3 and CB1 receptors on memory consolidation deficit in adult male Sprague-Dawley rats: An isobologram analysis.
Topics: Animals; Arachidonic Acids; Avoidance Learning; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; | 2016 |
Granisetron ameliorates acetic acid-induced colitis in rats.
Topics: Acetic Acid; Animals; Anti-Inflammatory Agents; Biguanides; Colitis; Colon; Dexamethasone; Disease M | 2010 |
Tropisetron ameliorates ischemic brain injury in an embolic model of stroke.
Topics: Analysis of Variance; Animals; Biguanides; Blood Gas Analysis; Brain Edema; Brain Infarction; Brain | 2011 |
The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Biguanides; Citalopram; Disease Models, Animal; Dose | 2011 |
Effect of pharmacologically induced smooth muscle activation on permeability in murine colitis.
Topics: Albuterol; Animals; Biguanides; Carbachol; Colitis; Dextran Sulfate; Disease Models, Animal; Female; | 2003 |
Effects of the 5-HT3 receptor agonist 1-(m-chlorophenyl)-biguanide in the rat kindling model of epilepsy.
Topics: Amygdala; Animals; Biguanides; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy; K | 1997 |