1-(3-chlorophenyl)biguanide has been researched along with Anxiety in 3 studies
1-(3-chlorophenyl)biguanide: RN given refers to parent cp; a 5-HT3 receptor agonist
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuroanatomical findings revealed that CB1 cannabinoid and 5-HT3 receptors are coexpressed by a subtype of gamma-aminobutyric acid (GABA)ergic interneurons in the prefrontal cortex, hippocampus, and basolateral amygdala, three brain regions that are crucial for the control of anxiety." | 3.75 | Interactions between the anxiogenic effects of CB1 gene disruption and 5-HT3 neurotransmission. ( Aliczki, M; Halasz, J; Haller, J; Mikics, E; Vas, J, 2009) |
| " In this study, we investigated the effect of MCI-225 in anxiety models in comparison with diazepam, ondansetron, maprotiline, imipramine, and trazodone." | 3.71 | The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism. ( Eguchi, J; Inomata, Y; Saito, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lopes, LT | 1 |
| Canto-de-Souza, L | 1 |
| Baptista-de-Souza, D | 1 |
| de Souza, RR | 1 |
| Nunes-de-Souza, RL | 1 |
| Canto-de-Souza, A | 1 |
| Mikics, E | 1 |
| Vas, J | 1 |
| Aliczki, M | 1 |
| Halasz, J | 1 |
| Haller, J | 1 |
| Eguchi, J | 1 |
| Inomata, Y | 1 |
| Saito, K | 1 |
3 other studies available for 1-(3-chlorophenyl)biguanide and Anxiety
| Article | Year |
|---|---|
The interplay between 5-HT
Topics: Animals; Anxiety; Behavior, Animal; Biguanides; Male; Mice; Ondansetron; Periaqueductal Gray; Pipera | 2022 |
Interactions between the anxiogenic effects of CB1 gene disruption and 5-HT3 neurotransmission.
Topics: Animals; Anxiety; Behavior, Animal; Biguanides; Cannabinoid Receptor Modulators; gamma-Aminobutyric | 2009 |
The anxiolytic-like effect of MCI-225, a selective NA reuptake inhibitor with 5-HT3 receptor antagonism.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Biguanid | 2001 |