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1-(2-trifluoromethylphenyl)imidazole and Pain

1-(2-trifluoromethylphenyl)imidazole has been researched along with Pain in 1 studies

1-(2-trifluoromethylphenyl)imidazole: an inhibitor of neuronal nitric oxide synthase in mouse

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Compound 16 was shown to reverse thermal hyperalgesia in vivo in the Chung model of neuropathic pain."1.37Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain. ( Andrews, JS; Annedi, SC; Bunton, D; Christie, L; Lee, DK; Maddaford, SP; Mladenova, G; Porreca, F; Rakhit, S; Ramnauth, J; Zhang, D, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Annedi, SC1
Maddaford, SP1
Mladenova, G1
Ramnauth, J1
Rakhit, S1
Andrews, JS1
Lee, DK1
Zhang, D1
Porreca, F1
Bunton, D1
Christie, L1

Other Studies

1 other study available for 1-(2-trifluoromethylphenyl)imidazole and Pain

ArticleYear
Discovery of N-(3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1H-indol-6-yl) thiophene-2-carboximidamide as a selective inhibitor of human neuronal nitric oxide synthase (nNOS) for the treatment of pain.
    Journal of medicinal chemistry, 2011, Oct-27, Volume: 54, Issue:20

    Topics: Analgesics; Coronary Vessels; Cytochrome P-450 Enzyme Inhibitors; Hot Temperature; Humans; Hyperalge

2011