Compounds > 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol
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1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol and Fibrosarcoma

1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol has been researched along with Fibrosarcoma in 5 studies

*Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed) [MeSH]

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arundel-Suto, CM; Elliott, WE; Leopold, WR; Sebolt-Leopold, JS; Stier, MA; Suto, MJ; Werbel, LM1
Dachs, GU; Firth, JD; Harris, AL; Patterson, AV; Ratcliffe, PJ; Stratford, IJ; Townsend, KM1
Airley, R; Cowen, RL; Honess, D; Jaffar, M; Patterson, AV; Saunders, M; Stratford, IJ; Telfer, BA; van der Kogel, AJ; Williams, KJ; Wolf, CR1
Herman, TS; Holden, SA; Rudolph, MB; Teicher, BA1
Walton, MI; Workman, P1

Other Studies

5 other study(ies) available for 1-(2-nitro-1-imidazolyl)-3-aziridino-2-propanol and Fibrosarcoma

ArticleYear
A new class of analogues of the bifunctional radiosensitizer alpha-(1-aziridinylmethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069): the cycloalkylaziridines.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:8

    Topics: Animals; Aziridines; Cell Line; Cell Survival; Chemical Phenomena; Chemistry; Cricetinae; Fibrosarcoma; Mice; Misonidazole; Molecular Structure; Nitroimidazoles; Oxygen; Pyrans; Radiation-Sensitizing Agents; Structure-Activity Relationship

1991
Targeting gene expression to hypoxic tumor cells.
    Nature medicine, 1997, Volume: 3, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Hypoxia; Cytosine Deaminase; DNA-Binding Proteins; Fibrosarcoma; Flucytosine; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Nuclear Proteins; Nucleoside Deaminases; Oxygen; Phosphoglycerate Kinase; Prodrugs; Promoter Regions, Genetic; Recombinant Fusion Proteins; Transcription Factors; Tumor Cells, Cultured

1997
Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours.
    Gene therapy, 2002, Volume: 9, Issue:14

    Topics: Animals; Combined Modality Therapy; Female; Fibrosarcoma; Genetic Therapy; Genetic Vectors; Humans; Hypoxia; Mice; Mice, Nude; Misonidazole; NADPH-Ferrihemoprotein Reductase; Neoplasm Transplantation; Nitroimidazoles; Prodrugs; Radiation Tolerance; Radiation-Sensitizing Agents; Transplantation, Heterologous; Tumor Cells, Cultured

2002
Effect of oxygenation, pH and hyperthermia on RSU-1069 in vitro and in vivo with radiation in the FSaIIC murine fibrosarcoma.
    Cancer letters, 1991, Volume: 59, Issue:2

    Topics: Animals; Benzimidazoles; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Radiation; Fibrosarcoma; Fluorescent Dyes; Hydrogen-Ion Concentration; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Misonidazole; Oxygen; Radiation-Sensitizing Agents; Tumor Cells, Cultured

1991
Pharmacokinetics and metabolism of the mixed-function hypoxic cell sensitizer prototype RSU 1069 in mice.
    Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:4

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Chromatography, High Pressure Liquid; Female; Fibrosarcoma; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Misonidazole; Radiation-Sensitizing Agents

1988