Compounds > 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea
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1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Rectal Neoplasms

1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea has been researched along with Rectal Neoplasms in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Drewinko, B; Yang, LY1
Earhart, RH; Engstrom, PF; Hahn, RG; Moertel, C; Ramirez, G; Woodhouse, CL1
Bedikian, AY; Bennetts, RW; Bodey, GP; Karlin, DA; Stewart, DJ; Stroehlein, JR1
Larson, R; Le Beau, MM; Leichman, L; Levin, B; Shepard, KV1
Baker, LH; Pazdur, R; Samson, MK1

Other Studies

5 other study(ies) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Rectal Neoplasms

ArticleYear
The lethal activity and repair inhibition capacity of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (NSC 95466, PCNU), a nitrosourea with low carbamoylating activity.
    Investigational new drugs, 1983, Volume: 1, Issue:3

    Topics: Antineoplastic Agents; Cell Line; Colonic Neoplasms; DNA Repair; Humans; Kinetics; Nitrosourea Compounds; Rectal Neoplasms

1983
Phase II trial of PCNU in advanced colorectal carcinoma. An Eastern Cooperative Oncology Group pilot study.
    American journal of clinical oncology, 1984, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Female; Hematologic Diseases; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Rectal Neoplasms; Time Factors

1984
Phase II evaluation of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (PCNU, NSC 95466) in patients with metastatic colorectal cancer.
    American journal of clinical oncology, 1983, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Colonic Neoplasms; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Nitrosourea Compounds; Rectal Neoplasms

1983
Acute leukemia occurring after radiotherapy and chemotherapy with a nitrosourea, PCNU.
    Investigational new drugs, 1988, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Cytarabine; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Nitrosourea Compounds; Rectal Neoplasms; Translocation, Genetic

1988
PCNU: phase II evaluation in advanced colorectal carcinoma.
    Investigational new drugs, 1988, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Colonic Neoplasms; Drug Evaluation; Humans; Middle Aged; Nitrosourea Compounds; Rectal Neoplasms

1988