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1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Glioma

1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea has been researched along with Glioma in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19904 (44.44)18.7374
1990's5 (55.56)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benjamin, RS; Bodey, GP; Burgess, MA; Leavens, M; Stewart, DJ; Valdivieso, M1
Casper, ES; Gordon, C; Gralla, RJ; Kalman, LA; Kris, MG; Woodcock, TM1
Arusell, RM; Brown, LD; Buckner, JC; Dinapoli, RP; Earle, JD; Krook, JE; Maier, JA; O'Fallon, JR; Scheithauer, BW; Tschetter, LK1
Buckner, JC; Cascino, TL; Dinapoli, RP; O'Fallon, JR; Schaefer, PL; Schomberg, P; Taylor, BV1
Shapiro, WR1
Bigner, DD; Bodell, WJ; Elion, GB; Friedman, HS; Schold, SC; Wang, AM1
Bodey, GP; Feun, LG; Leavens, ME; Maor, M; Savaraj, N; Stewart, DJ1
Allen, JC; Bloom, J; Ertel, I; Evans, A; Hammond, D; Jenkin, D; Jones, H; Levin, V; Sposto, R; Wara, W1
Benoit, BC; Grahovac, Z; Gupta, S; Hopkins, HS; Hugenholtz, H; Locke, L; Maroun, JA; Richard, MT; Russel, NA; Stewart, DJ1

Reviews

2 review(s) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Glioma

ArticleYear
Chemotherapy of malignant gliomas: studies of the BTCG.
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Nitrosourea Compounds; Prognosis; Survival Analysis

1992
Brain tumors in children: current cooperative and institutional chemotherapy trials in newly diagnosed and recurrent disease.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Glioma; Humans; Medulloblastoma; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nitrosourea Compounds

1986

Trials

4 trial(s) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Glioma

ArticleYear
Phase III comparative evaluation of PCNU and carmustine combined with radiation therapy for high-grade glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1993, Volume: 11, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Multivariate Analysis; Nitrosourea Compounds; Survival Analysis; Treatment Outcome

1993
Effects of radiation and chemotherapy on cognitive function in patients with high-grade glioma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cognition; Cranial Irradiation; Disease Progression; Female; Glioma; Humans; Intelligence Tests; Interferon-alpha; Male; Middle Aged; Nitrosourea Compounds; Prospective Studies; Survival Rate

1998
Chemotherapy of malignant gliomas: studies of the BTCG.
    Revue neurologique, 1992, Volume: 148, Issue:6-7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Nitrosourea Compounds; Prognosis; Survival Analysis

1992
Brain tumors in children: current cooperative and institutional chemotherapy trials in newly diagnosed and recurrent disease.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Glioma; Humans; Medulloblastoma; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nitrosourea Compounds

1986

Other Studies

5 other study(ies) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Glioma

ArticleYear
Phase I study of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (NSC 95466) in adults with solid tumors.
    Cancer research, 1980, Volume: 40, Issue:10

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Brain Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Glioblastoma; Glioma; Humans; Hypotension; Male; Middle Aged; Mustard Compounds; Nausea; Neoplasms; Nitrosourea Compounds; Thrombocytopenia

1980
Phase I trial of PCNU.
    Cancer treatment reports, 1983, Volume: 67, Issue:11

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Drug Evaluation; Female; Glioma; Humans; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms; Nitrosourea Compounds; Thrombocytopenia

1983
Positive therapeutic interaction between thiopurines and alkylating drugs in human glioma xenografts.
    Cancer chemotherapy and pharmacology, 1991, Volume: 27, Issue:4

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; DNA; Glioma; Humans; Mercaptopurine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Nitrosourea Compounds; Procarbazine; Survival Rate; Thioguanine; Transplantation, Heterologous

1991
Pilot study of PCNU and cranial radiation therapy in the treatment of patients with malignant gliomas.
    Oncology, 1990, Volume: 47, Issue:5

    Topics: Adult; Antineoplastic Agents; Astrocytoma; Combined Modality Therapy; Female; Glioblastoma; Glioma; Humans; Middle Aged; Nitrosourea Compounds; Pilot Projects

1990
Phase I study of intracarotid PCNU.
    Journal of neuro-oncology, 1987, Volume: 5, Issue:3

    Topics: Adult; Aged; Alkylating Agents; Antineoplastic Agents; Brain Neoplasms; Carotid Artery, Internal; Drug Evaluation; Glioma; Humans; Infusions, Intra-Arterial; Middle Aged; Nitrosourea Compounds

1987