1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea has been researched along with Brain Neoplasms in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (76.47) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benjamin, RS; Bodey, GP; Burgess, MA; Leavens, M; Stewart, DJ; Valdivieso, M | 1 |
| Allen, J; Hancock, C; Tan, CT | 1 |
| Benjamin, RS; Bodey, GP; Burgess, MA; Feun, LG; Leavens, ME; Savaraj, N; Stewart, DJ | 1 |
| Deen, DF; Weinkam, RJ | 1 |
| Burger, PC; Byar, DP; Green, SB; Mahaley, MS; Malkin, MG; Pistenmaa, DA; Ransohoff, J; Shapiro, WR; Strike, TA; Vogel, FS | 1 |
| Arusell, RM; Brown, LD; Buckner, JC; Dinapoli, RP; Earle, JD; Krook, JE; Maier, JA; O'Fallon, JR; Scheithauer, BW; Tschetter, LK | 1 |
| Buckner, JC; Cascino, TL; Dinapoli, RP; O'Fallon, JR; Schaefer, PL; Schomberg, P; Taylor, BV | 1 |
| Shapiro, WR | 1 |
| Bigner, DD; Friedman, HS; Schold, SC | 1 |
| Carrasco, CH; Charnsangavej, C; Feun, LG; Gianturco, C; Lee, YY; Savaraj, N; Wallace, S; Yung, WK | 1 |
| D'Incalci, M; Day, R; Erickson, LC; Kohn, KW; Kornblith, PL; Laurent, G; Sariban, E; Smith, BH; Zlotogorski, C | 1 |
| Allen, JC; Bloom, J; Ertel, I; Evans, A; Hammond, D; Jenkin, D; Jones, H; Levin, V; Sposto, R; Wara, W | 1 |
| Allen, JC; Hancock, C; Tan, C; Walker, R | 1 |
| Benoit, BC; Grahovac, Z; Gupta, S; Hopkins, HS; Hugenholtz, H; Locke, L; Maroun, JA; Richard, MT; Russel, NA; Stewart, DJ | 1 |
| Dean, PN; Deen, DF; Gray, JW; Linfoot, PA; Marton, LJ | 1 |
| Badnitsky, S; Burger, P; Krischer, J; Ragab, AH; Van Eys, J | 1 |
| Benjamin, RS; Bodey, GP; Burgess, MA; Feldman, LD; Feun, LG; Papadopoulos, N; Plager, C; Savaraj, N; Yap, BS | 1 |
3 review(s) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Brain Neoplasms
| Article | Year |
|---|---|
Chemotherapy of malignant gliomas: studies of the BTCG.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Nitrosourea Compounds; Prognosis; Survival Analysis | 1992 |
New drugs and new delivery techniques.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Bleomycin; Brain Neoplasms; Carboplatin; Carmustine; Cisplatin; Etoposide; Humans; Infusions, Intra-Arterial; Interferons; Nitrosourea Compounds; Organoplatinum Compounds; Rats | 1985 |
Brain tumors in children: current cooperative and institutional chemotherapy trials in newly diagnosed and recurrent disease.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Glioma; Humans; Medulloblastoma; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nitrosourea Compounds | 1986 |
5 trial(s) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Brain Neoplasms
| Article | Year |
|---|---|
Superiority of PCNU over AZQ in the treatment of primary brain tumors: results of a prospective randomized trial (81-20) by the Brain Tumor Study Group.
Topics: Antineoplastic Agents; Aziridines; Benzoquinones; Brain Neoplasms; Child; Humans; Middle Aged; Nitrosourea Compounds; Prospective Studies; Recurrence; Survival Analysis | 1994 |
Phase III comparative evaluation of PCNU and carmustine combined with radiation therapy for high-grade glioma.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Multivariate Analysis; Nitrosourea Compounds; Survival Analysis; Treatment Outcome | 1993 |
Effects of radiation and chemotherapy on cognitive function in patients with high-grade glioma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carmustine; Cognition; Cranial Irradiation; Disease Progression; Female; Glioma; Humans; Intelligence Tests; Interferon-alpha; Male; Middle Aged; Nitrosourea Compounds; Prospective Studies; Survival Rate | 1998 |
Chemotherapy of malignant gliomas: studies of the BTCG.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carmustine; Cisplatin; Combined Modality Therapy; Fluorouracil; Glioma; Humans; Injections, Intra-Arterial; Injections, Intravenous; Nitrosourea Compounds; Prognosis; Survival Analysis | 1992 |
Brain tumors in children: current cooperative and institutional chemotherapy trials in newly diagnosed and recurrent disease.
Topics: Adolescent; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Brain Neoplasms; Brain Stem; Child; Child, Preschool; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Glioma; Humans; Medulloblastoma; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasm Staging; Nitrosourea Compounds | 1986 |
11 other study(ies) available for 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidinyl)-1-nitrosourea and Brain Neoplasms
| Article | Year |
|---|---|
Phase I study of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (NSC 95466) in adults with solid tumors.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Brain Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Glioblastoma; Glioma; Humans; Hypotension; Male; Middle Aged; Mustard Compounds; Nausea; Neoplasms; Nitrosourea Compounds; Thrombocytopenia | 1980 |
Phase II trial of PCNU in children with recurrent brain tumors and Hodgkin's disease.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Drug Evaluation; Female; Hodgkin Disease; Humans; Infant; Infusions, Parenteral; Male; Neoplasm Recurrence, Local; Neoplasms, Nerve Tissue; Nitrosourea Compounds | 1984 |
A phase II trial of 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl)-1-nitrosourea (PCNU, NSC 95466) in recurrent malignant brain tumors.
Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Drug Evaluation; Humans; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds | 1983 |
Quantitative dose-response relations for the cytotoxic activity of chloroethylnitrosoureas in cell culture.
Topics: Animals; Biotransformation; Brain Neoplasms; Carmustine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Lomustine; Mustard Compounds; Neoplasms, Experimental; Nitrosourea Compounds; Rats; Semustine; Structure-Activity Relationship; Time Factors | 1982 |
Chemotherapy of subcutaneous and intracranial human medulloblastoma xenografts in athymic nude mice.
Topics: Animals; Azacitidine; Brain Neoplasms; Cell Line; Cytarabine; Doxorubicin; Humans; Medulloblastoma; Melphalan; Mice; Mice, Nude; Mitoguazone; Neoplasm Transplantation; Nitrosourea Compounds; Skin Neoplasms; Vidarabine Phosphate | 1986 |
DNA cross-linking responses of human malignant glioma cell strains to chloroethylnitrosoureas, cisplatin, and diaziquone.
Topics: Aziridines; Benzoquinones; Brain Neoplasms; Carmustine; Cells, Cultured; Cisplatin; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Drug Resistance; Ethylnitrosourea; Glioblastoma; Humans; Neoplasm Proteins; Nitrosourea Compounds | 1987 |
PCNU and recurrent childhood brain tumors.
Topics: Adolescent; Alkylating Agents; Antineoplastic Agents; Brain Neoplasms; Child; Child, Preschool; Drug Evaluation; Female; Humans; Male; Nitrosourea Compounds; Spinal Cord Neoplasms | 1987 |
Phase I study of intracarotid PCNU.
Topics: Adult; Aged; Alkylating Agents; Antineoplastic Agents; Brain Neoplasms; Carotid Artery, Internal; Drug Evaluation; Glioma; Humans; Infusions, Intra-Arterial; Middle Aged; Nitrosourea Compounds | 1987 |
Effect of cell cycle position on the survival of 9L cells treated with nitrosoureas that alkylate, cross-link, and carbamoylate.
Topics: Alkylating Agents; Animals; Brain Neoplasms; Carbamates; Carmustine; Cell Cycle; Cell Line; Cell Survival; Cross-Linking Reagents; Ethylnitrosourea; Lomustine; Nitroso Compounds; Nitrosourea Compounds; Rats; Structure-Activity Relationship | 1986 |
PCNU in the treatment of recurrent medulloblastoma and ependymoma--a POG Study.
Topics: Adolescent; Brain Neoplasms; Child; Child, Preschool; Drug Evaluation; Ependymoma; Humans; Medulloblastoma; Neoplasm Recurrence, Local; Nitrosourea Compounds; Thrombocytopenia; Tomography, X-Ray Computed | 1986 |
A phase II trial of PCNU in patients with malignant melanoma and central nervous system metastases.
Topics: Brain Neoplasms; Drug Evaluation; Humans; Injections, Intravenous; Leukopenia; Melanoma; Nitrosourea Compounds; Skin Neoplasms; Thrombocytopenia | 1985 |