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1-(2-chloroethyl)-1-nitrosourea and Leukemia L 1210

1-(2-chloroethyl)-1-nitrosourea has been researched along with Leukemia L 1210 in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's3 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dolan, ME; Weinkam, RJ1
Joshua, AV; Lown, JW; McLaughlin, LW1
Hansch, C; Jow, PY; Leo, A; Montgomery, JA; Schmidt, C1
Erickson, LC; Gibson, NW; Hickman, JA1
Bodell, WJ; Chen, FX; Church, KM; Gold, B; Zhang, Y1
Erickson, LC; Kurpad, C; Maze, R; Pegg, AE; Williams, DA1
Kann, HE1
Filippeschi, S; Spinelli, L; Ubezio, P1
Ducore, JM; Rosenstein, BS1

Other Studies

9 other study(ies) available for 1-(2-chloroethyl)-1-nitrosourea and Leukemia L 1210

ArticleYear
An analysis of 1-(2-chloroethyl)-1-nitrosourea activity at the cellular level.
    Journal of medicinal chemistry, 1983, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Carmustine; Cell Survival; Drug Evaluation, Preclinical; Ethylnitrosourea; Leukemia L1210; Leukemia P388; Lomustine; Mice; Nitrosourea Compounds; Streptozocin; Structure-Activity Relationship

1983
Noval antitumor nitrosoureas and related compounds and their reactions with DNA.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:7

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Cross-Linking Reagents; DNA; Leukemia L1210; Mice; Nitrosourea Compounds; Structure-Activity Relationship

1980
Antitumor structure-activity relations. Nitrosoureas vs. L-1210 leukemia.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:10

    Topics: Animals; Antineoplastic Agents; Leukemia L1210; Mice; Models, Theoretical; Nitrosourea Compounds; Solubility; Structure-Activity Relationship

1980
Effects of the antitumor agent 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one on the DNA of mouse L1210 cells.
    Cancer research, 1984, Volume: 44, Issue:5

    Topics: Animals; Cell Division; Dacarbazine; DNA, Neoplasm; Ethylnitrosourea; Imidazoles; Kinetics; Leukemia L1210; Mice; Neoplasm Proteins; Nitrogen Mustard Compounds; Protein Binding

1984
DNA crosslinking, sister chromatid exchange and cytotoxicity of N-2-chloroethylnitrosoureas tethered to minor groove binding peptides.
    Carcinogenesis, 1993, Volume: 14, Issue:5

    Topics: Alkylation; Animals; Base Sequence; Carcinogens; Carmustine; Cell Survival; Dipeptides; DNA; Ethylnitrosourea; Kinetics; Leukemia L1210; Mice; Molecular Sequence Data; Plasmids; Sister Chromatid Exchange; Time Factors; Tumor Cells, Cultured

1993
Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: Animals; Antineoplastic Agents; Carcinoma; Ethylnitrosourea; Female; Genetic Vectors; Guanine; Hematopoietic Stem Cells; Humans; Leukemia L1210; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Retroviridae; Tumor Cells, Cultured

1999
Comparison of biochemical and biological effects of four nitrosoureas with differing carbamoylating activities.
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; DNA, Neoplasm; Ethylnitrosourea; Leukemia L1210; Lomustine; Neoplasm Proteins; Nitrosourea Compounds; RNA, Neoplasm; Streptozocin; Time Factors

1978
Method for kinetic analysis of drug-induced cell cycle perturbations.
    Cytometry, 1991, Volume: 12, Issue:2

    Topics: Animals; Bromodeoxyuridine; Cell Count; Cell Cycle; DNA; Ethylnitrosourea; Flow Cytometry; Kinetics; Leukemia L1210; Mice; Staining and Labeling; Tumor Cells, Cultured

1991
Theophylline release of replicon initiation inhibition by nitrosoureas correlates with the synergistic killing in L1210 leukemia in vitro.
    Mutation research, 1985, Volume: 146, Issue:1

    Topics: Animals; Carmustine; Cell Survival; Cells, Cultured; DNA, Neoplasm; Drug Synergism; Ethylnitrosourea; Leukemia L1210; Mice; Replicon; Theophylline

1985