Compounds > 1-(2-chloroethyl)-1-nitrosourea
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1-(2-chloroethyl)-1-nitrosourea and Cancer of Colon

1-(2-chloroethyl)-1-nitrosourea has been researched along with Cancer of Colon in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erickson, LC; Zlotogorski, C1
Bibby, MC; Double, JA; Dumont, P; McCormick, JE; McElhinney, RS; Radacic, M1
Atassi, G; Bibby, MC; Double, JA; Dumont, P; McCormick, JE; McElhinney, RS; Pratesi, G; Radacic, M1
Bibby, MC; Double, JA; McCormick, JE; McElhinney, RS1

Other Studies

4 other study(ies) available for 1-(2-chloroethyl)-1-nitrosourea and Cancer of Colon

ArticleYear
Pretreatment of normal human fibroblasts and human colon carcinoma cells with MNNG allows chloroethylnitrosourea to produce DNA interstrand crosslinks not observed in cells treated with chloroethylnitrosourea alone.
    Carcinogenesis, 1983, Volume: 4, Issue:6

    Topics: Cell Line; Cell Survival; Colonic Neoplasms; DNA; Ethylnitrosourea; Female; Fibroblasts; Humans; Methylnitronitrosoguanidine; Nitrosourea Compounds; Pregnancy; Time Factors

1983
Nucleoside analogs. 14. The synthesis of antitumor activity in mice of molecular combinations of 5-fluorouracil and N-(2-Chloroethyl)-N-nitrosourea moieties separated by a three-carbon chain.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Ethylnitrosourea; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Nucleosides

1996
Nucleoside analogues: 8. Some isomers of B.3839, the original 5-fluorouracil/nitrosourea molecular combination, and their effect on colon, breast and lung tumours in mice.
    Anti-cancer drug design, 1989, Volume: 4, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colonic Neoplasms; Drug Screening Assays, Antitumor; Ethylnitrosourea; Fluorouracil; Isomerism; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Nitrosourea Compounds

1989
Nucleoside analogues. 5. Molecular combination of anti-cancer drugs: activity of 5-fluorouracil/nitrosourea combinations against mouse colon tumours.
    Anti-cancer drug design, 1986, Volume: 1, Issue:2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Ethylnitrosourea; Fluorouracil; Mice; Nucleosides; Structure-Activity Relationship

1986