1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with Bone Loss, Osteoclastic in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rogers, MJ | 1 |
| Chan, JM; Flessner, R; Gómez, AO; González-Pacanowska, D; Jennings, S; Kosztowski, T; Kotsikorou, E; Meints, GA; Morita, CT; Odeh, S; Oldfield, E; Papapoulos, SE; Raker, AM; Sanders, JM; Schwerdtfeger, C; Song, Y; van Beek, ER; Wang, H; Zhang, Y | 1 |
| Bayless, AV; Brown, RJ; Ebetino, FH; Rogers, MJ; Russell, RG; Watts, DJ; Xiong, X | 1 |
| Bayless, AV; Blackburn, GM; Ebetino, FH; Ji, X; Rogers, MJ; Russell, RG; Watts, DJ; Xiong, X | 1 |
| Brown, RJ; Löwik, CW; Papapoulos, SE; van Beek, E; Watts, DJ | 1 |
| Brown, RJ; Grove, JE; Watts, DJ | 1 |
| Martin, MB; Oldfield, E; Szabo, CM | 1 |
1 review(s) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
From molds and macrophages to mevalonate: a decade of progress in understanding the molecular mode of action of bisphosphonates.
Topics: Animals; Apoptosis; Bone Resorption; Dictyostelium; Diphosphonates; Humans; Macrophages; Mevalonic Acid; Osteoclasts; Protein Prenylation | 2004 |
6 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Bone Resorption; Calcium; Dictyostelium; Diphosphonates; Geranyltranstransferase; Humans; In Vitro Techniques; Leishmania major; Metatarsal Bones; Mice; Models, Molecular; Pyridinium Compounds; Quantitative Structure-Activity Relationship; Receptors, Antigen, T-Cell, gamma-delta; Trypanocidal Agents | 2005 |
Structure-activity relationships of new heterocycle-containing bisphosphonates as inhibitors of bone resorption and as inhibitors of growth of Dictyostelium discoideum amoebae.
Topics: Animals; Bone Resorption; Cell Division; Dictyostelium; Diphosphonates; Heterocyclic Compounds; Methylation; Structure-Activity Relationship | 1995 |
Inhibitory effects of bisphosphonates on growth of amoebae of the cellular slime mold Dictyostelium discoideum.
Topics: Animals; Bone Resorption; Dictyostelium; Diphosphonates; Dose-Response Relationship, Drug; Osteoclasts; Structure-Activity Relationship | 1994 |
Differential effects of aminosubstituted analogs of hydroxy bisphosphonates on the growth of Dictyostelium discoideum.
Topics: Amines; Animals; Bone Density; Bone Resorption; Dictyostelium; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Female; Hindlimb; Mice; Pamidronate; Structure-Activity Relationship | 1998 |
The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase.
Topics: Alendronate; Alkyl and Aryl Transferases; Amino Acid Sequence; Animals; Base Sequence; Bone Resorption; Dictyostelium; Diphosphonates; DNA Primers; Etidronic Acid; Farnesyl-Diphosphate Farnesyltransferase; Geranyltranstransferase; Molecular Sequence Data; Risedronic Acid; RNA, Messenger; Sequence Homology, Amino Acid | 2000 |
An investigation of bone resorption and Dictyostelium discoideum growth inhibition by bisphosphonate drugs.
Topics: Alkyl and Aryl Transferases; Animals; Bone Resorption; Crystallography, X-Ray; Dictyostelium; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Inhibitory Concentration 50; Models, Molecular; Quantitative Structure-Activity Relationship; Rats | 2002 |