Compounds > (endo-n-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2-3-dihydro-3-isopropyl-2-oxo-1h-benzimidazol-1-carboxamide

(endo-n-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2-3-dihydro-3-isopropyl-2-oxo-1h-benzimidazol-1-carboxamide and Arrhythmias--Cardiac

(endo-n-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2-3-dihydro-3-isopropyl-2-oxo-1h-benzimidazol-1-carboxamide has been researched along with Arrhythmias--Cardiac* in 1 studies

Other Studies

1 other study(ies) available for (endo-n-8-methyl-8-azabicyclo-(3.2.1)oct-3-yl)-2-3-dihydro-3-isopropyl-2-oxo-1h-benzimidazol-1-carboxamide and Arrhythmias--Cardiac

ArticleYear
Voltage gated ion channels blockade is the underlying mechanism of BIMU8 induced cardiotoxicity.
    Toxicology letters, 2017, Aug-05, Volume: 277

    BIMU8 is a 5-HT4

    Topics: Action Potentials; Arrhythmias, Cardiac; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Calcium Channels, L-Type; Cardiotoxicity; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Heart Rate; HEK293 Cells; Humans; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Risk Assessment; Serotonin 5-HT4 Receptor Agonists; Transfection; Voltage-Gated Sodium Channel Blockers

2017