(3h)2-carbomethoxy-3-(4-fluorophenyl)tropane and Parkinson Disease

(3h)2-carbomethoxy-3-(4-fluorophenyl)tropane has been researched along with Parkinson Disease in 37 studies

*Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) [MeSH]

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (35.14)	18.2507
2000's	16 (43.24)	29.6817
2010's	7 (18.92)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Li, X; Li, Y; Mutaerbieke, N; Qin, Y; Yibulayin, A; Zhang, Q; Zhao, X	1
Gong, X; Liang, X; Liu, L; Wang, X; Zhang, W	1
Ding, ZT; Ge, JJ; Huang, SF; Liu, SY; Wang, J; Wang, YX; Wu, JJ; Wu, P; Zhao, J; Zuo, CT	1
Chen, T; Chen, Y; Guo, Z; Wang, R; Xu, B; Zhang, J; Zhu, H	1
Bohnen, NI; Constantine, GM; Gedela, S; Herath, P; Moore, RY	1
Iida, A; Inoue, N; Kakiuchi, T; Kondo, Y; Muramatsu, S; Nakano, I; Nakayama, T; Okuno, T; Ono, F; Suzuki, Y; Takino, N; Terao, K; Tsukada, H	1
Gai, Y; Guo, LH; Jiang, ZH; Qin, GW; Zhao, G; Zheng, XW	1
Farrer, MJ; Hattori, N; Imai, H; Inoue, Y; Ishii, K; Ishiwata, K; Kachergus, JM; Kitagawa, M; Kono, S; Mizoguchi, K; Mizuno, Y; Nishioka, K; Obi, T; Ross, OA; Takanashi, M	1
Cui, XX; Guo, JF; Jiang, H; Lei, LF; Long, ZG; Pan, Q; Shen, L; Song, XW; Tang, BS; Wang, JL; Xia, K; Xiao, B; Yan, XX	1
Futatsubashi, M; Ouchi, Y; Torizuka, T; Yagi, S; Yokokura, M; Yoshihara, Y; Yoshikawa, E	1
Alstrup, AK; Doudet, DJ; Gjedde, A; Høltzermann, M; Jakobsen, S; Landau, AM; Møller, A; Nahimi, A; Simonsen, M; Vang, K; Wegener, G	1
Huang, T; Liang, X; Shi, X; Tang, G; Wang, H; Zhang, X	1
Liu, S; Shen, L; Tian, ZM; Wang, RM; Wieman, J; Yan, Y; Yin, F; Zhao, QJ	1
Chen, JC; Hwang, JJ; Liao, MH; Lin, KJ; Pan, WH; Ting, G; Wey, SP; Yen, TC	1
Andren, PE; Svenningsson, P; Zhang, X	1
Hattori, N; Ida, H; Kono, S; Miyajima, H; Mizuno, Y; Ouchi, Y; Sakamoto, M; Shirakawa, K; Sugiura, T; Suzuki, H; Takahashi, Y; Tomiyama, H	1
Bohnen, NI; Constantine, GM; Gedela, S; Kuwabara, H; Mathis, CA; Moore, RY; Studenski, SA	1
Cepeda, IL; Cornfeldt, ML; Doudet, DJ; Flores, J; O'Kusky, JR	1
Bohnen, NI; Constantine, GM; Kuwabara, H; Mathis, CA; Moore, RY	1
Madras, BK	1
Isacson, O	1
Dannals, RF; Ehlers, MD; Frost, JJ; Ravert, HT; Reich, SG; Rosier, AJ; Smith, JS; Snyder, SH	1
Laihinen, A; Någren, K; Rinne, JO; Rinne, UK; Ruotsalainen, U; Ruottinen, H	1
Byon, C; Elmaleh, DR; Fischman, AJ; Hanson, RN; Liang, AY; Madras, BK; Meltzer, PC; Shoup, TM	1
Ding, YS; Fowler, JS; Gatley, SJ; Volkow, ND; Wang, GJ	1
Brashear, A; Farlow, MR; Hutchins, GD; Mulholland, GK; Siemers, ER; Zheng, QH	1
Bergman, J; Eronen, E; Haaparanta, M; Oikonen, V; Rinne, JO; Ruottinen, H; Solin, O; Sonninen, P	1
Dannals, RF; Frost, JJ; Ilgin, N; Ravert, HT; Reich, SG; Zubieta, J	1
Futatsubashi, M; Iyo, M; Okada, H; Ouchi, Y; Sakamoto, M; Sekine, Y; Yoshikawa, E	1
Brownell, AL; Isacson, O; Jenkins, BG	1
Futatsubashi, M; Kanno, T; Nobezawa, S; Okada, H; Ouchi, Y; Sakamoto, M; Torizuka, T; Yoshikawa, E	1
Berciano, J; Figols, J; González, AM; Pascual, J; Pazos, A	1
Bergman, J; Haaparanta, M; Kaasinen, V; Nurmi, E; Rinne, JO; Ruottinen, HM; Solin, O	1
Bergman, J; Eskola, O; Hinkka, SM; Nurmi, E; Rinne, JO; Solin, O; Sonninen, P	1
Futatsubashi, M; Kanno, T; Nobezawa, S; Okada, H; Ouchi, Y; Tanaka, K; Torizuka, T; Yoshikawa, E	1
Bergman, J; Eskola, O; Nurmi, E; Rinne, OJ; Ruottinen, HM; Solin, O	1
Kaufman, MJ; Madras, BK	1

Trials

4 trial(s) available for (3h)2-carbomethoxy-3-(4-fluorophenyl)tropane and Parkinson Disease

Article	Year
The influence of residual nor-β-CFT in 11C CFT injection on the Parkinson disease diagnosis: a 11C CFT PET study. Clinical nuclear medicine, 2012, Volume: 37, Issue:8 Topics: Carbon Radioisotopes; Cocaine; Drug Residues; Female; Fluorodeoxyglucose F18; Humans; Injections, Intravenous; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography	2012
Transplantation of human retinal pigment epithelium cells in the treatment for Parkinson disease. CNS neuroscience & therapeutics, 2012, Volume: 18, Issue:12 Topics: Aged; Aged, 80 and over; Antigens, CD; Bucladesine; Carbon Isotopes; Cell Differentiation; Cells, Cultured; Cocaine; Dopamine Uptake Inhibitors; Female; Fetus; Flow Cytometry; Growth Substances; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Middle Aged; Neural Stem Cells; Neurons; Parkinson Disease; Pituitary Adenylate Cyclase-Activating Polypeptide; Positron-Emission Tomography; Retinal Pigment Epithelium; Severity of Illness Index; Time Factors; Treatment Outcome; Tretinoin	2012
Reproducibility and effect of levodopa on dopamine transporter function measurements: a [18F]CFT PET study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:11 Topics: Adult; Aged; Antiparkinson Agents; Biological Transport; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Reproducibility of Results; Tomography, Emission-Computed	2000
Changes in dopamine availability in the nigrostriatal and mesocortical dopaminergic systems by gait in Parkinson's disease. Brain : a journal of neurology, 2001, Volume: 124, Issue:Pt 4 Topics: Aged; Arteries; Blood Pressure; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Frontal Lobe; Gait; Gyrus Cinguli; Heart Rate; Humans; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Substantia Nigra; Tomography, Emission-Computed; Walking	2001

Other Studies

33 other study(ies) available for (3h)2-carbomethoxy-3-(4-fluorophenyl)tropane and Parkinson Disease

Article	Year
Positron emission tomography/computed tomography dual imaging using 18-fluorine flurodeoxyglucose and 11C-labeled 2-β-carbomethoxy-3-β-(4-fluorophenyl) tropane for the severity assessment of Parkinson disease. Medicine, 2020, Volume: 99, Issue:14 Topics: Aged; Basal Ganglia; Brain; Carbon Radioisotopes; Cocaine; Female; Fluorine Radioisotopes; Glucose; Humans; Male; Middle Aged; Parkinson Disease; Positron Emission Tomography Computed Tomography; Prospective Studies; Severity of Illness Index	2020
Relation between microPET imaging and rotational behavior in a parkinsonian rat model induced by medial forebrain bundle axotomy. Behavioural brain research, 2014, May-15, Volume: 265 Topics: Animals; Apomorphine; Axotomy; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine Uptake Inhibitors; Functional Laterality; Male; Medial Forebrain Bundle; Parkinson Disease; Raclopride; Radionuclide Imaging; Rats; Rats, Wistar; Stereotyped Behavior; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase	2014
Onset-related subtypes of Parkinson's disease differ in the patterns of striatal dopaminergic dysfunction: A positron emission tomography study. Parkinsonism & related disorders, 2015, Volume: 21, Issue:12 Topics: Adult; Age of Onset; Aged; Carbon Radioisotopes; Caudate Nucleus; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Female; Humans; Male; Middle Aged; Neuroimaging; Organ Specificity; Parkinson Disease; Positron-Emission Tomography; Putamen; Radiopharmaceuticals; Tissue Distribution	2015
Suite PET/CT neuroimaging for the diagnosis of Parkinson's disease: statistical parametric mapping analysis. Nuclear medicine communications, 2017, Volume: 38, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Brain; Brain Mapping; Case-Control Studies; Cocaine; Dopamine Plasma Membrane Transport Proteins; Female; Fluorodeoxyglucose F18; Functional Neuroimaging; Glucose; Humans; Male; Middle Aged; Molecular Imaging; Parkinson Disease; Positron Emission Tomography Computed Tomography; Raclopride; Radiopharmaceuticals; Receptors, Dopamine D2; Young Adult	2017
Selective hyposmia in Parkinson disease: association with hippocampal dopamine activity. Neuroscience letters, 2008, Dec-05, Volume: 447, Issue:1 Topics: Aged; Carbon Isotopes; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Hippocampus; Humans; Male; Mental Status Schedule; Middle Aged; Models, Biological; Neural Pathways; Olfaction Disorders; Parkinson Disease; Radionuclide Imaging	2008
Multitracer assessment of dopamine function after transplantation of embryonic stem cell-derived neural stem cells in a primate model of Parkinson's disease. Synapse (New York, N.Y.), 2009, Volume: 63, Issue:7 Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Cocaine; Disease Models, Animal; Dopamine; Dopamine Agents; Embryonic Stem Cells; Levodopa; Macaca fascicularis; Methamphetamine; Movement Disorders; Neurons; Parkinson Disease; Positron-Emission Tomography; Putamen; Raclopride; Tyrosine 3-Monooxygenase	2009
In vitro dopaminergic neuroprotective and in vivo antiparkinsonian-like effects of Delta 3,2-hydroxybakuchiol isolated from Psoralea corylifolia (L.). Cellular and molecular life sciences : CMLS, 2009, Volume: 66, Issue:9 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antiparkinson Agents; Cell Line; CHO Cells; Cocaine; Cricetinae; Cricetulus; Dopamine; Dopamine Agents; Humans; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Norepinephrine; Parkinson Disease; Phenols; Psoralea; Rats; Rats, Sprague-Dawley; Synaptosomes; Tyrosine 3-Monooxygenase	2009
Expanding the clinical phenotype of SNCA duplication carriers. Movement disorders : official journal of the Movement Disorder Society, 2009, Sep-15, Volume: 24, Issue:12 Topics: Adult; Aged; alpha-Synuclein; Brain; Carbon Isotopes; Chromosome Mapping; Cocaine; Family Health; Female; Fluorodeoxyglucose F18; Gene Dosage; Gene Duplication; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Parkinson Disease; Phenotype; Positron-Emission Tomography; Raclopride; REM Sleep Behavior Disorder; Sensory Thresholds; Smell; Young Adult	2009
Analysis of SCA2 and SCA3/MJD repeats in Parkinson's disease in mainland China: genetic, clinical, and positron emission tomography findings. Movement disorders : official journal of the Movement Disorder Society, 2009, Oct-15, Volume: 24, Issue:13 Topics: Adult; Aged; Ataxin-3; Ataxins; Carbon Isotopes; China; Cocaine; DNA Mutational Analysis; Family Health; Female; Humans; Male; Middle Aged; Nerve Tissue Proteins; Nuclear Proteins; Parkinson Disease; Positron-Emission Tomography; Repressor Proteins; Trinucleotide Repeat Expansion	2009
Progression from unilateral to bilateral parkinsonism in early Parkinson disease: implication of mesocortical dopamine dysfunction by PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:8 Topics: Adult; Aged; Cerebral Cortex; Cocaine; Disease Progression; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Functional Laterality; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Prognosis; Radiopharmaceuticals; Regression Analysis	2010
Serotonergic modulation of receptor occupancy in rats treated with L-DOPA after unilateral 6-OHDA lesioning. Journal of neurochemistry, 2012, Volume: 120, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antiparkinson Agents; Autoradiography; Carbon Isotopes; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dyskinesia, Drug-Induced; Female; Functional Laterality; Levodopa; Microdialysis; Motor Activity; Oxidopamine; Parkinson Disease; Positron-Emission Tomography; Protein Binding; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Serotonin; Serotonergic Neurons; Serotonin Receptor Agonists	2012
Biodistribution study of [99mTc] TRODAT-1 alone or combined with other dopaminergic drugs in mice with macroautoradiography. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2002, Volume: 57, Issue:1 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Autoradiography; Brain; Cocaine; Dopamine Agents; Humans; Levodopa; Male; Methylphenidate; Mice; Mice, Inbred ICR; Organotechnetium Compounds; Parkinson Disease; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution; Tropanes	2002
Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease. Brain research, 2006, Jun-20, Volume: 1095, Issue:1 Topics: Adrenergic Agents; Animals; Antiparkinson Agents; Brain-Derived Neurotrophic Factor; Cocaine; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug Administration Schedule; Gene Expression Regulation; Levodopa; Male; Oxidopamine; Parkinson Disease; Protein Binding; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; RNA, Messenger; Subthalamic Nucleus; Tritium	2006
Dopaminergic neuronal dysfunction associated with parkinsonism in both a Gaucher disease patient and a carrier. Journal of the neurological sciences, 2007, Jan-31, Volume: 252, Issue:2 Topics: Adult; Carbon Radioisotopes; Cocaine; Dopamine; Dopamine Antagonists; Gaucher Disease; Heterozygote; Humans; Male; Neurons; Parkinson Disease; Positron-Emission Tomography; Raclopride	2007
Selective hyposmia and nigrostriatal dopaminergic denervation in Parkinson's disease. Journal of neurology, 2007, Volume: 254, Issue:1 Topics: Aged; Cocaine; Corpus Striatum; Denervation; Dopamine; Dopamine Uptake Inhibitors; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neural Pathways; Olfaction Disorders; Parkinson Disease; Positron-Emission Tomography; Substantia Nigra	2007
Human retinal pigment epithelial cell implants ameliorate motor deficits in two rat models of Parkinson disease. Journal of neuropathology and experimental neurology, 2007, Volume: 66, Issue:7 Topics: Analysis of Variance; Animals; Autoradiography; Cell Transplantation; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Uptake Inhibitors; Extremities; Functional Laterality; Humans; Male; Motor Neuron Disease; Parkinson Disease; Pigment Epithelium of Eye; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Time Factors; Transplantation, Heterologous	2007
Grooved pegboard test as a biomarker of nigrostriatal denervation in Parkinson's disease. Neuroscience letters, 2007, Sep-13, Volume: 424, Issue:3 Topics: Aged; Biomarkers; Cocaine; Female; Humans; Isotopes; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Psychomotor Performance; Striatonigral Degeneration	2007
11C-WIN 35,428 for detecting dopamine depletion in mild Parkinson's disease. Annals of neurology, 1994, Volume: 35, Issue:3 Topics: Carbon Radioisotopes; Cocaine; Dopamine; Humans; Parkinson Disease; Tomography, Emission-Computed	1994
Clinical and preclinical PET correlates of parkinsonism with 11C-WIN 35,428. Annals of neurology, 1994, Volume: 35, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carbon Radioisotopes; Cocaine; Humans; Parkinson Disease; Parkinson Disease, Secondary; Tomography, Emission-Computed	1994
Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease. Annals of neurology, 1993, Volume: 34, Issue:3 Topics: Biomarkers; Brain; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Middle Aged; Nerve Tissue Proteins; Organ Specificity; Parkinson Disease; Putamen; Tomography, Emission-Computed	1993
PET examination of the monoamine transporter with [11C]beta-CIT and [11C]beta-CFT in early Parkinson's disease. Synapse (New York, N.Y.), 1995, Volume: 21, Issue:2 Topics: Adult; Biological Transport; Brain; Carbon Radioisotopes; Cocaine; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Neuropeptides; Parkinson Disease; Time Factors; Tissue Distribution; Tomography, Emission-Computed; Vesicular Biogenic Amine Transport Proteins	1995
Preparation and biological evaluation of iodine-125-IACFT: a selective SPECT agent for imaging dopamine transporter sites. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:7 Topics: Animals; Autoradiography; Brain; Carrier Proteins; Citalopram; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Saimiri; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed, Single-Photon	1996
Positron emission tomography radioligands for dopamine transporters and studies in human and nonhuman primates. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Parkinson Disease; Primates; Radioligand Assay; Radiopharmaceuticals; Reference Values; Substance-Related Disorders; Tomography, Emission-Computed	1998
PET imaging of the pre-synaptic dopamine uptake sites in rapid-onset dystonia-parkinsonism (RDP). Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:1 Topics: Adult; Aged; Brain Mapping; Carbon Radioisotopes; Cocaine; Corpus Striatum; Diagnosis, Differential; Dopamine; Dopamine Uptake Inhibitors; Dystonia; Female; Homovanillic Acid; Humans; Male; Middle Aged; Parkinson Disease; Parkinson Disease, Secondary; Pilot Projects; Receptors, Dopamine; Receptors, Presynaptic; Tomography, Emission-Computed	1999
Striatal uptake of a novel PET ligand, [18F]beta-CFT, is reduced in early Parkinson's disease. Synapse (New York, N.Y.), 1999, Volume: 31, Issue:2 Topics: Aged; Animals; Caudate Nucleus; Cocaine; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Putamen; Tomography, Emission-Computed	1999
PET imaging of the dopamine transporter in progressive supranuclear palsy and Parkinson's disease. Neurology, 1999, Apr-12, Volume: 52, Issue:6 Topics: Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Supranuclear Palsy, Progressive; Tomography, Emission-Computed	1999
Alterations in binding site density of dopamine transporter in the striatum, orbitofrontal cortex, and amygdala in early Parkinson's disease: compartment analysis for beta-CFT binding with positron emission tomography. Annals of neurology, 1999, Volume: 45, Issue:5 Topics: Aged; Amygdala; Binding Sites; Brain; Carrier Proteins; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Frontal Lobe; Humans; Kinetics; Magnetic Resonance Imaging; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Orbit; Parkinson Disease; Radiography; Time Factors; Tomography, Emission-Computed	1999
Dopamine imaging markers and predictive mathematical models for progressive degeneration in Parkinson's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1999, Volume: 53, Issue:3 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Aged; Animals; Biomarkers; Cocaine; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Haplorhini; Humans; Macaca fascicularis; Magnetic Resonance Imaging; Male; Models, Biological; Parkinson Disease; Tomography, Emission-Computed; Visual Cortex	1999
Presynaptic and postsynaptic dopaminergic binding densities in the nigrostriatal and mesocortical systems in early Parkinson's disease: a double-tracer positron emission tomography study. Annals of neurology, 1999, Volume: 46, Issue:5 Topics: Aged; Benzazepines; Brain; Carbon Radioisotopes; Carrier Proteins; Caudate Nucleus; Cerebellum; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Functional Laterality; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Receptors, Dopamine D1; Reference Values; Substantia Nigra; Tomography, Emission-Computed	1999
Loss of dopamine uptake sites and dopamine D2 receptors in striatonigral degeneration. Brain research, 2000, Jan-03, Volume: 852, Issue:1 Topics: Aged; Autoradiography; Benzamides; Cadaver; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Receptors, Dopamine D2; Reference Values; Striatonigral Degeneration	2000
Progression in Parkinson's disease: a positron emission tomography study with a dopamine transporter ligand [18F]CFT. Annals of neurology, 2000, Volume: 47, Issue:6 Topics: Aged; Antiparkinson Agents; Brain; Carrier Proteins; Caudate Nucleus; Cerebellum; Cocaine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Fluorine Radioisotopes; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Parkinson Disease; Putamen; Time Factors; Tomography, Emission-Computed	2000
[(18)F]FDOPA and [(18)F]CFT are both sensitive PET markers to detect presynaptic dopaminergic hypofunction in early Parkinson's disease. Synapse (New York, N.Y.), 2001, Jun-01, Volume: 40, Issue:3 Topics: Aged; Brain; Caudate Nucleus; Cocaine; Dihydroxyphenylalanine; Dopamine; Down-Regulation; Female; Fluorine Radioisotopes; Functional Laterality; Humans; Male; Middle Aged; Parkinson Disease; Positron-Emission Tomography; Predictive Value of Tests; Presynaptic Terminals; Putamen; Synaptic Transmission	2001
Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum. Synapse (New York, N.Y.), 1991, Volume: 9, Issue:1 Topics: Aged; Autoradiography; Carrier Proteins; Caudate Nucleus; Cocaine; Corpus Striatum; Humans; Parkinson Disease; Putamen; Receptors, Drug; Reference Values; Tritium	1991