(2e-4e-6e-10e)-3-7-11-15-tetramethyl-2-4-6-10-14-hexadecapentaenoic-acid has been researched along with Nasopharyngeal-Neoplasms* in 2 studies
2 other study(ies) available for (2e-4e-6e-10e)-3-7-11-15-tetramethyl-2-4-6-10-14-hexadecapentaenoic-acid and Nasopharyngeal-Neoplasms
Article | Year |
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Inhibitory effect of retinoid (E5166) on cell growth and suppressive effect on Epstein-Barr virus early-antigen induction by n-butyrate in nasopharyngeal hybrid cells.
The in vitro proliferation and colony-forming activity (plating efficiency) of Epstein-Barr virus (EBV) nuclear antigen-positive nasopharyngeal hybrid cells were inhibited by one of the retinoid, polyprenoic acid; E5166. It was dependent on retinoid concentration. Furthermore, an induction of EBV early antigen after treatment with 4 mM n-butyrate was markedly suppressed by E5166 and this was similar to the previously reported effects of retinoid acid on iododeoxyuridine (IUDR) and 12-O-tetra-decanoyl-phorbol-13-acetate (TPA) induction. These results support to lead a clinical application of E5166 for combination chemotherapy in patients with nasopharyngeal carcinoma. Topics: Antigens, Viral, Tumor; Butyrates; Butyric Acid; Carcinoma; Cells, Cultured; Fluorescent Antibody Technique; Herpesvirus 4, Human; Humans; Nasopharyngeal Neoplasms; Tretinoin; Tumor Virus Infections | 1987 |
[Inhibitory effect of retinoid on early antigen induction of Epstein-Barr virus].
Topics: Antigens, Viral; Butyrates; Cells, Cultured; Herpesvirus 4, Human; Humans; Interferon Type I; Nasopharyngeal Neoplasms; Tretinoin | 1987 |