Compounds > (2--(benzyloxycarbonylaminomethyl)biphenyl-2-carboxylic-acid-2-(2-pyridyl)ethylamide)

(2--(benzyloxycarbonylaminomethyl)biphenyl-2-carboxylic-acid-2-(2-pyridyl)ethylamide) and Neoplasms

(2--(benzyloxycarbonylaminomethyl)biphenyl-2-carboxylic-acid-2-(2-pyridyl)ethylamide) has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for (2--(benzyloxycarbonylaminomethyl)biphenyl-2-carboxylic-acid-2-(2-pyridyl)ethylamide) and Neoplasms

Article	Year
Selective TASK-1 Inhibitor with a Defined Structure-Activity Relationship Reduces Cancer Cell Proliferation and Viability. Journal of medicinal chemistry, 2022, 11-24, Volume: 65, Issue:22 Chemical structures of selective blockers of TASK channels contain aromatic groups and amide bonds. Using this rationale, we designed and synthesized a series of compounds based on 3-benzamidobenzoic acid. These compounds block TASK-1 channels by binding to the central cavity. The most active compound is 3-benzoylamino Topics: Binding Sites; Cell Proliferation; Humans; MCF-7 Cells; Models, Molecular; Neoplasms; Structure-Activity Relationship	2022

Article

Year

Selective TASK-1 Inhibitor with a Defined Structure-Activity Relationship Reduces Cancer Cell Proliferation and Viability.

Journal of medicinal chemistry, 2022, 11-24, Volume: 65, Issue:22

Chemical structures of selective blockers of TASK channels contain aromatic groups and amide bonds. Using this rationale, we designed and synthesized a series of compounds based on 3-benzamidobenzoic acid. These compounds block TASK-1 channels by binding to the central cavity. The most active compound is 3-benzoylamino

Topics: Binding Sites; Cell Proliferation; Humans; MCF-7 Cells; Models, Molecular; Neoplasms; Structure-Activity Relationship

2022