zotepine has been researched along with clozapine in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.00) | 18.7374 |
| 1990's | 14 (35.00) | 18.2507 |
| 2000's | 14 (35.00) | 29.6817 |
| 2010's | 7 (17.50) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| Choudhary, MS; Craigo, SC; Meltzer, HY; Monsma, FJ; Roth, BL; Shen, Y; Sibley, DR; Uluer, A | 1 |
| De Loore, K; Gommeren, W; Janssen, PF; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van Gompel, P | 1 |
| Grinde, E; Herrick-Davis, K; Teitler, M | 1 |
| Bristow, LJ; Hutson, PH; Rowley, M | 1 |
| Wermuth, CG | 1 |
| Herrick-Davis, K; Purohit, A; Smith, C; Teitler, M | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Anderer, P; Chwatal, K; Grünberger, J; Saletu, B | 1 |
| Anderer, P; Grünberger, J; Linzmayer, L; Saletu, B | 1 |
| Fujiwara, T; Kikuchi, H; Mori, J; Ono, T; Satoh, H; Shimomura, K | 1 |
| Czyrak, A; Frankiewicz, T; Maj, J; Rogóz, Z; Skuza, G | 1 |
| Matsubara, R | 1 |
| Czyrak, A; Jaros, T; Maj, J; Moryl, E | 1 |
| Behrens, S; Gattaz, WF; Schummer, B | 1 |
| Marr, I; Schlicker, E | 1 |
| Atkinson, J; Heal, DJ; Needham, PL; Skill, MJ | 1 |
| Bauer, U; Gallhofer, B; Gruppe, H; Krieger, S; Lis, S; Meyer-Lindenberg, A | 1 |
| Franz, M; Gallhofer, B; Lis, S; Plüddemann, K | 1 |
| Fleischhacker, WW | 1 |
| Müssigbrodt, HE; Wetterling, T | 1 |
| Naber, D | 1 |
| Möller, HJ | 1 |
| McAskill, R; Taylor, DM | 1 |
| Kapur, S; Remington, G | 1 |
| Hilger, E; Kasper, S | 1 |
| Hashimoto, K; Iyo, M; Kanahara, N; Komatsu, N; Kumakiri, C; Okamura, N; Shimizu, E | 1 |
| Lawrie, S; McIntosh, A; Nadeem, Z | 2 |
| Bubeníková, V; Dockery, C; Horácek, J; Pálenícek, T; Votava, M | 1 |
| Bai, YM; Chen, JY; Lin, CC; Liou, YJ; Wang, YC | 1 |
| Hunger, H; Kissling, W; Komossa, K; Leucht, S; Rummel-Kluge, C; Schmid, F; Schwarz, S | 1 |
| Hunger, H; Kissling, W; Komossa, K; Leucht, S; Rummel-Kluge, C; Schmid, F; Schwarz, S; Subramanian, S | 1 |
| Asenjo Lobos, C; Hunger, H; Komossa, K; Leucht, S; Rummel-Kluge, C; Schmid, F; Schwarz, S | 1 |
| Chang, YT; Chen, CC; Chen, WJ; Kuo, CJ; Lee, WC; Liao, YT; Shau, WY; Tsai, SY; Yang, SY | 1 |
| Bai, YM; Chen, JY; Chen, TT; Chiu, HJ; Lin, CC; Liou, YJ; Wang, YC | 1 |
| Abe, Y; Hamamatsu, S; Hattori, Y; Ikegami, Y; Iwata, N; Matsuo, K; Matsuoka, Y; Obara, K; Shioda, N; Tanaka, Y; Yamaki, F; Yoshio, T; Yoshioka, K | 1 |
| Hashimoto, N; Ishikawa, S; Ito, YM; Kusumi, I; Okubo, R; Sato, N; Sawagashira, R; Yamamura, R | 1 |
12 review(s) available for zotepine and clozapine
| Article | Year |
|---|---|
Current and novel approaches to the drug treatment of schizophrenia.
Topics: Animals; Antipsychotic Agents; Cholinergic Agonists; Disease Models, Animal; Dopamine Antagonists; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Mice; Mice, Transgenic; Nitric Oxide Synthase; Receptor, Serotonin, 5-HT2A; Receptors, AMPA; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotensin; Receptors, Serotonin; Schizophrenia; Serotonin Antagonists | 2001 |
Selective optimization of side activities: another way for drug discovery.
Topics: Animals; Biological Availability; Combinatorial Chemistry Techniques; Databases, Factual; Drug Design; Humans; Patents as Topic; Pharmaceutical Preparations; Structure-Activity Relationship | 2004 |
Clozapine: a comparison with other novel antipsychotics.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Double-Blind Method; Drug Resistance; Humans; Olanzapine; Pirenzepine; Placebos; Psychotic Disorders; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Schizophrenia; Schizophrenic Psychology; Treatment Outcome | 1999 |
[New i.e. atypical neuroleptic agents for negative symptoms of schizophrenia: results and methodological problems of evaluation].
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Double-Blind Method; Dyskinesia, Drug-Induced; Humans; Imidazoles; Indoles; Neurotransmitter Agents; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Schizophrenic Psychology; Sulpiride; Thiazoles | 2000 |
Atypical antipsychotics and weight gain--a systematic review.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Risperidone; Sulpiride; Thiazoles; Weight Gain | 2000 |
Atypical antipsychotics: new directions and new challenges in the treatment of schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Dopamine Antagonists; Drug Monitoring; Haloperidol; Humans; Imidazoles; Indoles; Olanzapine; Piperazines; Pirenzepine; Quetiapine Fumarate; Receptors, Dopamine D2; Receptors, Dopamine D4; Risperidone; Schizophrenia; Schizophrenic Psychology; Serotonin Antagonists; Sulpiride; Thiazoles; Treatment Outcome | 2001 |
[Atypical neuroleptics: new approaches to drug therapy of schizophrenic disorders].
Topics: Aged; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Controlled Clinical Trials as Topic; Dibenzothiazepines; Dibenzothiepins; Haloperidol; Humans; Imidazoles; Indoles; Multicenter Studies as Topic; Olanzapine; Piperazines; Pirenzepine; Placebos; Quetiapine Fumarate; Risperidone; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulpiride; Thiazoles | 2000 |
Schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Haloperidol; Humans; Olanzapine; Patient Compliance; Perazine; Pimozide; Risperidone; Schizophrenia; Sulpiride | 2003 |
Schizophrenia.
Topics: Amisulpride; Antipsychotic Agents; Chlorpromazine; Clozapine; Cognitive Behavioral Therapy; Dibenzothiepins; Family Therapy; Haloperidol; Humans; Patient Compliance; Risperidone; Schizophrenia; Secondary Prevention; Sulpiride; Thioridazine | 2005 |
Zotepine versus other atypical antipsychotics for schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Dibenzothiepins; Humans; Randomized Controlled Trials as Topic; Schizophrenia | 2010 |
Zotepine versus other atypical antipsychotics for schizophrenia.
Topics: Antipsychotic Agents; Clozapine; Dibenzothiepins; Humans; Randomized Controlled Trials as Topic; Remoxipride; Risperidone; Schizophrenia | 2010 |
Clozapine versus other atypical antipsychotics for schizophrenia.
Topics: Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiazepines; Dibenzothiepins; Humans; Olanzapine; Piperazines; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Thiazoles | 2010 |
4 trial(s) available for zotepine and clozapine
| Article | Year |
|---|---|
[Relation between blood levels and average quantitative EEG and psychometrically assessed pharmacodynamic changes following zotepine].
Topics: Adult; Affect; Antipsychotic Agents; Arousal; Attention; Clozapine; Dibenzothiepins; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Female; Humans; Male; Neuropsychological Tests; Psychometrics | 1991 |
Comparative placebo-controlled pharmacodynamic studies with zotepine and clozapine utilizing pharmaco-EEG and psychometry.
Topics: Adult; Antipsychotic Agents; Attention; Blood Pressure; Clozapine; Dibenzazepines; Dibenzothiepins; Double-Blind Method; Electroencephalography; Emotions; Female; Humans; Male; Psychometrics; Psychomotor Performance; Pulse; Random Allocation; Reaction Time; Time Factors | 1987 |
Improvement of cognitive function in schizophrenic patients receiving clozapine or zotepine: results from a double-blind study.
Topics: Adult; Antipsychotic Agents; Clozapine; Cognition; Dibenzothiepins; Double-Blind Method; Female; Humans; Male; Maze Learning; Schizophrenia; Schizophrenic Psychology | 1997 |
Switching from clozapine to zotepine in patients with schizophrenia: a 12-week prospective, randomized, rater blind, and parallel study.
Topics: Adult; Aged; Antipsychotic Agents; Clozapine; Dibenzothiepins; Dose-Response Relationship, Drug; Drug Substitution; Humans; Middle Aged; Prospective Studies; Psychiatric Status Rating Scales; Schizophrenia; Severity of Illness Index; Single-Blind Method; Treatment Outcome; Young Adult | 2013 |
24 other study(ies) available for zotepine and clozapine
| Article | Year |
|---|---|
Binding of typical and atypical antipsychotic agents to 5-hydroxytryptamine-6 and 5-hydroxytryptamine-7 receptors.
Topics: Animals; Antipsychotic Agents; Cell Line; Molecular Structure; Rats; Receptors, Serotonin | 1994 |
Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding.
Topics: Animals; Antipsychotic Agents; Brain; Cells, Cultured; Clozapine; Haloperidol; Humans; Male; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone | 1996 |
Inverse agonist activity of atypical antipsychotic drugs at human 5-hydroxytryptamine2C receptors.
Topics: Animals; Antipsychotic Agents; COS Cells; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Radioligand Assay; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists | 2000 |
Stable expression of constitutively activated mutant h5HT6 and h5HT7 serotonin receptors: inverse agonist activity of antipsychotic drugs.
Topics: Amino Acid Substitution; Antipsychotic Agents; Cell Line; Cyclic AMP; Humans; Mutagenesis, Site-Directed; Mutation; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 2005 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Effect of zotepine on fenfluramine-induced hyperthermia in rats.
Topics: Animals; Antipsychotic Agents; Body Temperature; Clozapine; Dibenzothiepins; Fenfluramine; Male; Piperazines; Rats; Rats, Inbred Strains; Spiperone | 1984 |
Pharmacological action of zotepine and other antipsychotics on central 5-hydroxytryptamine receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Clozapine; Dibenzothiepins; Exploratory Behavior; Haloperidol; Isoxazoles; Male; Mice; Motor Activity; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
[A study on the pharmacological properties of atypical antipsychotic drugs: in vivo dopamine and serotonin receptor occupancy by atypical antipsychotic drugs in the rat brain].
Topics: Animals; Antipsychotic Agents; Autoradiography; Brain; Chlorpromazine; Clozapine; Dibenzothiepins; Flupenthixol; Haloperidol; In Vitro Techniques; Isoxazoles; Male; Piperidines; Pyrimidinones; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Risperidone | 1993 |
Pharmacological effects of zotepine and other antipsychotics on the central 5-HT2 receptors.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiepins; Haloperidol; Isoxazoles; Male; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone | 1993 |
Effects of zotepine, haloperidol and clozapine on MK-801-induced stereotypy and locomotion in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiepins; Dizocilpine Maleate; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Motor Activity; Rats; Rats, Wistar; Stereotyped Behavior | 1994 |
The moderate affinity of clozapine at H3 receptors is not shared by its two major metabolites and by structurally related and unrelated atypical neuroleptics.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Binding, Competitive; Clozapine; Dibenzothiepins; Dose-Response Relationship, Drug; Histamine Antagonists; Isotope Labeling; Male; Methylhistamines; Mice; Olanzapine; Pirenzepine; Rats; Rats, Wistar; Receptors, Histamine H3; Remoxipride; Risperidone; Structure-Activity Relationship; Thioridazine; Tritium | 1996 |
Zotepine: preclinical tests predict antipsychotic efficacy and an atypical profile.
Topics: Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Clozapine; Dibenzothiepins; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred Strains; Receptors, Dopamine; Time Factors | 1996 |
[Zotepin--its value and potentials for further development].
Topics: Animals; Antipsychotic Agents; Clozapine; Dibenzothiepins; Disease Models, Animal; Haloperidol; Humans; Rats; Schizophrenia | 1994 |
Conventional versus atypical neuroleptics: subjective quality of life in schizophrenic patients.
Topics: Adult; Analysis of Variance; Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Cross-Sectional Studies; Depression; Dibenzothiepins; Female; Humans; Male; Middle Aged; Quality of Life; Risperidone; Schizophrenia; Schizophrenic Psychology | 1997 |
Weight gain: side effect of atypical neuroleptics?
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Antipsychotic Agents; Body Mass Index; Clozapine; Delusions; Dibenzothiepins; Female; Humans; Long-Term Care; Male; Middle Aged; Psychotic Disorders; Retrospective Studies; Risperidone; Schizophrenia; Sulpiride; Weight Gain | 1999 |
[Atypical antipsychotics].
Topics: Acute Disease; Amisulpride; Antipsychotic Agents; Benzodiazepines; Clozapine; Cost-Benefit Analysis; Dibenzothiazepines; Dibenzothiepins; Dyskinesia, Drug-Induced; Germany; Humans; Neurotransmitter Agents; Olanzapine; Patient Compliance; Pirenzepine; Quetiapine Fumarate; Randomized Controlled Trials as Topic; Risperidone; Schizophrenia; Sulpiride | 2000 |
Protective effect of the antipsychotic drug zotepine on dizocilpine-induced neuropathological changes in rat retrosplenial cortex.
Topics: Animals; Antipsychotic Agents; Cerebral Cortex; Clozapine; Dibenzothiepins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; HSP70 Heat-Shock Proteins; Immunohistochemistry; Injections, Intraperitoneal; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2003 |
The effect of zotepine, risperidone, clozapine and olanzapine on MK-801-disrupted sensorimotor gating.
Topics: Acoustic Stimulation; Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzothiepins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Olanzapine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Muscarinic; Reflex, Startle; Risperidone | 2005 |
Treatment of clozapine-associated tardive dyskinesia.
Topics: Adult; Anti-Dyskinesia Agents; Antipsychotic Agents; Clozapine; Cross-Over Studies; Dibenzothiepins; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Male; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Substance Withdrawal Syndrome; Treatment Outcome | 2008 |
Second-generation antipsychotic medications and risk of pneumonia in schizophrenia.
Topics: Adult; Amisulpride; Antipsychotic Agents; Benzodiazepines; Case-Control Studies; Clozapine; Cohort Studies; Dibenzothiazepines; Dibenzothiepins; Drug Therapy, Combination; Female; Humans; Logistic Models; Male; Middle Aged; Olanzapine; Pneumonia; Quetiapine Fumarate; Risk Factors; Risperidone; Schizophrenia; Sulpiride; Taiwan | 2013 |
Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles.
Topics: Acetylcholine; Aging; Animals; Antipsychotic Agents; Chlorpromazine; Cholinergic Antagonists; Clozapine; Dibenzothiepins; Male; Mental Disorders; Methotrimeprazine; Muscle Contraction; Muscle, Smooth; Olanzapine; Quetiapine Fumarate; Rats, Wistar; Urinary Bladder; Urologic Diseases | 2021 |
The type rather than the daily dose or number of antipsychotics affects the incidence of hyperglycemic progression.
Topics: Adult; Antipsychotic Agents; Clozapine; Dibenzothiepins; Female; Haloperidol; Humans; Hyperglycemia; Incidence; Japan; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Schizophrenia | 2022 |