zopiclone n-oxide has been researched along with zopiclone in 5 studies
*zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007 [MeSH]
*zopiclone: S(+)-enantiomer of racemic zopiclone; azabicyclo(4.3.0)nonane; a nonbenzodiazepine; one of the so-called of Z drugs (zopiclone, eszopiclone, zolpidem, and zaleplon) for which there is some correlation with tumors; was term of zopiclone 2004-2007 [MeSH]
| Studies (zopiclone n-oxide) | Trials (zopiclone n-oxide) | Recent Studies (post-2010) (zopiclone n-oxide) | Studies (zopiclone) | Trials (zopiclone) | Recent Studies (post-2010) (zopiclone) |
|---|---|---|---|---|---|
| 7 | 1 | 1 | 747 | 204 | 184 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frydman, A; Gaillot, J; Le Liboux, A | 1 |
| Baune, B; Farinotti, R; Fernandez, C; Gimenez, F; Maradeix, V; Thuillier, A | 1 |
| Fung, HT; Kam, CW; Lai, CH; Lam, KK; Wong, OF | 1 |
| Jangid, AG; Mistri, HN; Pudage, A; Shrivastav, P | 1 |
| Bonato, PS; Tonon, MA | 1 |
1 trial(s) available for zopiclone n-oxide and zopiclone
| Article | Year |
|---|---|
HPLC-ESI-MS/MS validated method for simultaneous quantification of zopiclone and its metabolites, N-desmethyl zopiclone and zopiclone-N-oxide in human plasma.
Topics: Azabicyclo Compounds; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Fasting; Humans; Hypnotics and Sedatives; Mass Spectrometry; Piperazines; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
4 other study(ies) available for zopiclone n-oxide and zopiclone
| Article | Year |
|---|---|
Simultaneous determination of zopiclone and its two major metabolites (N-oxide and N-desmethyl) in human biological fluids by reversed-phase high-performance liquid chromatography.
Topics: Adolescent; Adult; Aged; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Kidney Failure, Chronic; Kinetics; Middle Aged; Piperazines; Spectrometry, Fluorescence | 1987 |
Determination of the enantiomers of zopiclone and its two chiral metabolites in urine using an automated coupled achiral-chiral chromatographic system.
Topics: Azabicyclo Compounds; Chromatography, Liquid; Humans; Hypnotics and Sedatives; Piperazines; Reproducibility of Results; Spectrometry, Fluorescence; Stereoisomerism | 1993 |
Two cases of methemoglobinemia following zopiclone ingestion.
Topics: Adult; Azabicyclo Compounds; Drug Overdose; Enzyme Inhibitors; Female; Humans; Hypnotics and Sedatives; Methemoglobinemia; Methylene Blue; Molecular Structure; Piperazines; Tablets | 2008 |
Capillary electrophoretic enantioselective determination of zopiclone and its impurities.
Topics: Azabicyclo Compounds; Drug Contamination; Drug Stability; Electrophoresis, Capillary; Least-Squares Analysis; Limit of Detection; Piperazines; Pyridines; Reproducibility of Results; Stereoisomerism; Tablets | 2012 |