Page last updated: 2024-09-04

zopiclone n-oxide and n-desmethylzopiclone

zopiclone n-oxide has been researched along with n-desmethylzopiclone in 4 studies

Compound Research Comparison

Studies
(zopiclone n-oxide)
Trials
(zopiclone n-oxide)
Recent Studies (post-2010)
(zopiclone n-oxide)
Studies
(n-desmethylzopiclone)
Trials
(n-desmethylzopiclone)
Recent Studies (post-2010) (n-desmethylzopiclone)
7111622

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frydman, A; Gaillot, J; Le Liboux, A1
Baune, B; Farinotti, R; Fernandez, C; Gimenez, F; Maradeix, V; Thuillier, A1
Fung, HT; Kam, CW; Lai, CH; Lam, KK; Wong, OF1
Jangid, AG; Mistri, HN; Pudage, A; Shrivastav, P1

Trials

1 trial(s) available for zopiclone n-oxide and n-desmethylzopiclone

ArticleYear
HPLC-ESI-MS/MS validated method for simultaneous quantification of zopiclone and its metabolites, N-desmethyl zopiclone and zopiclone-N-oxide in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Mar-15, Volume: 864, Issue:1-2

    Topics: Azabicyclo Compounds; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Fasting; Humans; Hypnotics and Sedatives; Mass Spectrometry; Piperazines; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2008

Other Studies

3 other study(ies) available for zopiclone n-oxide and n-desmethylzopiclone

ArticleYear
Simultaneous determination of zopiclone and its two major metabolites (N-oxide and N-desmethyl) in human biological fluids by reversed-phase high-performance liquid chromatography.
    Journal of chromatography, 1987, Jun-05, Volume: 417, Issue:1

    Topics: Adolescent; Adult; Aged; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Kidney Failure, Chronic; Kinetics; Middle Aged; Piperazines; Spectrometry, Fluorescence

1987
Determination of the enantiomers of zopiclone and its two chiral metabolites in urine using an automated coupled achiral-chiral chromatographic system.
    Journal of chromatography, 1993, Aug-11, Volume: 617, Issue:2

    Topics: Azabicyclo Compounds; Chromatography, Liquid; Humans; Hypnotics and Sedatives; Piperazines; Reproducibility of Results; Spectrometry, Fluorescence; Stereoisomerism

1993
Two cases of methemoglobinemia following zopiclone ingestion.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:2

    Topics: Adult; Azabicyclo Compounds; Drug Overdose; Enzyme Inhibitors; Female; Humans; Hypnotics and Sedatives; Methemoglobinemia; Methylene Blue; Molecular Structure; Piperazines; Tablets

2008