zopiclone has been researched along with n-desmethylzopiclone in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Frydman, A; Gaillot, J; Le Liboux, A | 1 |
| Daenens, P; Mannaert, E | 3 |
| Baune, B; Farinotti, R; Fernandez, C; Gimenez, F; Maradeix, V; Thuillier, A | 1 |
| Daenens, P; Mannaert, E; Tytgat, J | 1 |
| Carlson, JN; Glick, SD; Haskew, R; Jerussi, TP; Maisonneuve, IM; Wacker, J | 1 |
| France, CP; Jerussi, TP; McMahon, LR | 1 |
| Rochholz, G; Yang, LJ | 1 |
| Fung, HT; Kam, CW; Lai, CH; Lam, KK; Wong, OF | 1 |
| Jangid, AG; Mistri, HN; Pudage, A; Shrivastav, P | 1 |
| Ahlner, J; Kronstrand, R; Kugelberg, FC; Nilsson, GH | 1 |
| Hansen, SL; Johansen, SS; Kronstrand, R; Nielsen, MKK; Nilsson, G | 1 |
2 trial(s) available for zopiclone and n-desmethylzopiclone
| Article | Year |
|---|---|
Development of a fluorescence polarization immunoassay for the routine detection of N-desmethylzopiclone in urine samples.
Topics: Azabicyclo Compounds; Chromatography, High Pressure Liquid; Fluorescein-5-isothiocyanate; Fluorescence Polarization Immunoassay; Fluorescent Dyes; Humans; Hypnotics and Sedatives; Piperazines | 1996 |
HPLC-ESI-MS/MS validated method for simultaneous quantification of zopiclone and its metabolites, N-desmethyl zopiclone and zopiclone-N-oxide in human plasma.
Topics: Azabicyclo Compounds; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Fasting; Humans; Hypnotics and Sedatives; Mass Spectrometry; Piperazines; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
11 other study(ies) available for zopiclone and n-desmethylzopiclone
| Article | Year |
|---|---|
Simultaneous determination of zopiclone and its two major metabolites (N-oxide and N-desmethyl) in human biological fluids by reversed-phase high-performance liquid chromatography.
Topics: Adolescent; Adult; Aged; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Kidney Failure, Chronic; Kinetics; Middle Aged; Piperazines; Spectrometry, Fluorescence | 1987 |
Development of a radioimmunoassay for the determination of N-desmethylzopiclone in urine.
Topics: Animals; Antibody Specificity; Azabicyclo Compounds; Emergencies; Forensic Medicine; Humans; Hypnotics and Sedatives; Indicators and Reagents; Piperazines; Rabbits; Radioimmunoassay; Sensitivity and Specificity | 1994 |
Determination of the enantiomers of zopiclone and its two chiral metabolites in urine using an automated coupled achiral-chiral chromatographic system.
Topics: Azabicyclo Compounds; Chromatography, Liquid; Humans; Hypnotics and Sedatives; Piperazines; Reproducibility of Results; Spectrometry, Fluorescence; Stereoisomerism | 1993 |
Semi-preparative chiral resolution of zopiclone and N-desmethylzopiclone.
Topics: Azabicyclo Compounds; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Hypnotics and Sedatives; Optical Rotation; Piperazines; Stereoisomerism | 1996 |
Development of a stereospecific radioimmunoassay for the analysis of zopiclone and metabolites in urine.
Topics: Animals; Antibody Specificity; Azabicyclo Compounds; Cross Reactions; Humans; Hypnotics and Sedatives; Immune Sera; Piperazines; Rabbits; Radioimmunoassay; Sensitivity and Specificity; Stereoisomerism; Vaccines, Synthetic | 1996 |
Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Azabicyclo Compounds; Diazepam; Dose-Response Relationship, Drug; Electroshock; Hypnotics and Sedatives; Isomerism; Male; Motor Activity; Motor Skills; Piperazines; Rats; Rats, Long-Evans; Seizures | 2001 |
Stereoselective discriminative stimulus effects of zopiclone in rhesus monkeys.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Macaca mulatta; Male; Midazolam; Piperazines; Stereoisomerism; Substance Withdrawal Syndrome | 2003 |
[Determination of zopiclone in serum by reversed-phase high performance liquid chromatography].
Topics: Aged; Azabicyclo Compounds; Caffeine; Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Male; Piperazines | 2002 |
Two cases of methemoglobinemia following zopiclone ingestion.
Topics: Adult; Azabicyclo Compounds; Drug Overdose; Enzyme Inhibitors; Female; Humans; Hypnotics and Sedatives; Methemoglobinemia; Methylene Blue; Molecular Structure; Piperazines; Tablets | 2008 |
Validation of an LC-MS/MS method for the determination of zopiclone, N-desmethylzopiclone and 2-amino-5-chloropyridine in whole blood and its application to estimate the original zopiclone concentration in stored specimens.
Topics: Azabicyclo Compounds; Chromatography, Liquid; Drug Stability; Forensic Toxicology; Humans; Hypnotics and Sedatives; Models, Statistical; Piperazines; Pyridines; Specimen Handling; Tandem Mass Spectrometry | 2015 |
Distribution of zopiclone and main metabolites in hair following a single dose.
Topics: Adult; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Female; Forensic Toxicology; Hair; Hair Color; Humans; Hypnotics and Sedatives; Male; Piperazines; Tandem Mass Spectrometry; Time Factors; Young Adult | 2020 |