zopiclone has been researched along with diazepam in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (43.90) | 18.7374 |
| 1990's | 8 (19.51) | 18.2507 |
| 2000's | 7 (17.07) | 29.6817 |
| 2010's | 6 (14.63) | 24.3611 |
| 2020's | 2 (4.88) | 2.80 |
| Authors | Studies |
|---|---|
| Anzini, M; Basile, AS; Bruni, G; Cappelli, A; Giorgi, G; Langer, T; Romeo, MR; Vomero, S | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Hansen, PP; Paronen, P; Saano, V | 1 |
| Inoue, Y; Kataoka, Y; Koizumi, S; Miyazaki, A; Niwa, M; Shibata, K; Tominaga, K; Ueki, S | 1 |
| Albers, HE; Liou, SY; Shibata, S; Ueki, S | 1 |
| Blanchard, JC; Boireau, A; Doble, A; Dubedat, P; Laduron, PM | 1 |
| Betschart, J; Blanchard, JC; Piot, O; Stutzmann, JM | 1 |
| Ator, NA; Nierenberg, J | 1 |
| Nagatani, T; Sugihara, T; Ueki, S; Yamamoto, T | 1 |
| Joly, D; Sanger, DJ | 1 |
| Nishikawa, T; Scatton, B | 1 |
| Spealman, RD; Wettstein, JG | 1 |
| Ueki, S; Yamamoto, T | 1 |
| Spealman, RD | 1 |
| Nielsen, SP; Ranløv, PJ | 1 |
| Beaupré, A; Bourgouin, J; Phillips, R; Soucy, R | 1 |
| Hashimoto, M; Inanaga, K; Mizuki, Y; Tanaka, M; Tanaka, T | 1 |
| Burgevin, MC; Ferris, O; Gauthier, A; Guérémy, C; Heaulme, M; Le Fur, G; Mizoule, J; Uzan, A | 1 |
| Blanchard, JC; Boireau, A; Julou, L | 2 |
| Decobert, M; Depoortere, H; Honoré, L | 1 |
| Kato, S; Yanagita, T | 1 |
| Dundee, JW; Elwood, RJ; Hildebrand, PJ; Singleton, M | 2 |
| Yanagita, T | 2 |
| Brandeis, D; Kato, M; Okuma, T; Tsukahara, Y; Yamadera, H | 1 |
| Carlson, JN; Glick, SD; Haskew, R; Jerussi, TP; Maisonneuve, IM; Wacker, J | 1 |
| Brüne, M; Kahlert, I | 1 |
| France, CP; Jerussi, TP; McMahon, LR | 1 |
| Kiss, A; Mikkelsen, JD; Mirza, N; Søderman, A | 1 |
| Dickson, SJ; Irving, RC | 1 |
| Buchbinder, R; Richards, BL; Whittle, SL | 1 |
| Holmgren, A; Jones, AW | 1 |
| Jørgensen, MB; Osler, M | 1 |
| Apollonio, LG; Huestis, MA; Kaspar, CK; Lavins, ES; Michel, HM; Mitchell-Mata, CL; Sofalvi, S | 1 |
2 review(s) available for zopiclone and diazepam
| Article | Year |
|---|---|
Drug effects on the EEG of various species of laboratory animals.
Topics: 5-Hydroxytryptophan; Amantadine; Animals; Antihypertensive Agents; Azabicyclo Compounds; Brain; Cats; Chlormethiazole; Clonidine; Diazepam; Electroencephalography; Flunitrazepam; Guanabenz; Guanfacine; Guanidines; Imidazoles; Male; Nitrazepam; Pentobarbital; Phenylacetates; Piperazines; Piracetam; Rats; Sodium Oxybate; Yohimbine | 1983 |
Muscle relaxants for pain management in rheumatoid arthritis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Rheumatoid; Azabicyclo Compounds; Diazepam; Humans; Indomethacin; Muscle Relaxants, Central; Pain Management; Piperazines; Randomized Controlled Trials as Topic; Sulindac; Triazolam | 2012 |
7 trial(s) available for zopiclone and diazepam
| Article | Year |
|---|---|
Interactions and comparative effects of zopiclone, diazepam and lorazepam on psychomotor performance and on elimination pharmacokinetics in healthy volunteers.
Topics: Administration, Oral; Adult; Azabicyclo Compounds; Diazepam; Double-Blind Method; Drug Interactions; Female; Humans; Lorazepam; Male; Piperazines; Psychomotor Performance | 1992 |
Effect of zopiclone and diazepam on ventilatory response in normal human subjects.
Topics: Azabicyclo Compounds; Carbon Dioxide; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Respiration; Respiratory Function Tests | 1987 |
Respiratory center output following zopiclone or diazepam administration in patients with pulmonary disease.
Topics: Adult; Aged; Azabicyclo Compounds; Diazepam; Double-Blind Method; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Piperazines; Respiration; Respiratory Center; Respiratory Function Tests; Time Factors | 1988 |
A new physiological tool for assessing anxiolytic effects in humans: frontal midline theta activity.
Topics: Adult; Anti-Anxiety Agents; Azabicyclo Compounds; Diazepam; Electroencephalography; Humans; Male; Piperazines; Psychological Tests; Psychomotor Performance; Stress, Psychological; Theta Rhythm | 1983 |
Dose-finding and premedication studies with zopiclone.
Topics: Adult; Azabicyclo Compounds; Diazepam; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Piperazines; Preanesthetic Medication; Time Factors | 1983 |
Dose-finding and premedication studies with zopiclone.
Topics: Adult; Azabicyclo Compounds; Diazepam; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Piperazines; Preanesthetic Medication; Tablets; Taste; Time Factors | 1982 |
Zopiclone versus diazepam effects on EEG power maps in healthy volunteers.
Topics: Adult; Azabicyclo Compounds; Brain Mapping; Cross-Over Studies; Diazepam; Double-Blind Method; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Piperazines | 1997 |
32 other study(ies) available for zopiclone and diazepam
| Article | Year |
|---|---|
Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem.
Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Cerebral Cortex; Drug Design; Flunitrazepam; Imidazoles; Isoquinolines; Models, Molecular; Protein Conformation; Pyridines; Rats; Receptors, GABA-A; Structure-Activity Relationship | 1996 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Involvement of the dorsal hippocampus in mediation of the antianxiety action of tandospirone, a 5-hydroxytryptamine1A agonistic anxiolytic.
Topics: Animals; Anxiety; Azabicyclo Compounds; Behavior, Animal; Diazepam; Hippocampus; Hypnotics and Sedatives; Injections; Isoindoles; Male; Piperazines; Pyrimidines; Rats; Serotonin Antagonists | 1991 |
Effects of GABA and anxiolytics on the single unit discharge of suprachiasmatic neurons in rat hypothalamic slices.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Baclofen; Bicuculline; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Piperazines; Rats; Receptors, GABA-A; Suprachiasmatic Nucleus | 1990 |
Preferential decrease in dopamine utilization in prefrontal cortex by zopiclone, diazepam and zolpidem in unstressed rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Azabicyclo Compounds; Cerebral Cortex; Corpus Striatum; Diazepam; Dopamine; Flumazenil; Male; Piperazines; Pyridines; Rats; Rats, Inbred Strains; Stress, Physiological; Zolpidem | 1990 |
Cyclopyrrolones, unlike some benzodiazepines, do not induce physical dependence in mice.
Topics: Animals; Azabicyclo Compounds; Carbolines; Convulsants; Diazepam; Disease Models, Animal; Flunitrazepam; Hypnotics and Sedatives; Lorazepam; Male; Mice; Mice, Inbred Strains; Naphthyridines; Piperazines; Seizures; Structure-Activity Relationship; Substance-Related Disorders; Sulfur Compounds; Triazolam | 1990 |
Drug discrimination in rats successively trained to discriminate diazepam and pentobarbital.
Topics: Animals; Azabicyclo Compounds; Diazepam; Discrimination Learning; Discrimination, Psychological; Generalization, Stimulus; Male; Meprobamate; Pentobarbital; Piperazines; Rats; Rats, Inbred Strains; Triazolam | 1990 |
The effect of agonists at the GABA-benzodiazepine-receptor-complex on the proconflict effect induced by beta-CCM and pentetrazol in rats.
Topics: Aminooxyacetic Acid; Animals; Azabicyclo Compounds; Carbolines; Conflict, Psychological; Convulsants; Diazepam; Flumazenil; Hypnotics and Sedatives; Male; Pentylenetetrazole; Phenobarbital; Piperazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1988 |
Anxiolytic drugs and the acquisition of conditioned fear in mice.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Chlordiazepoxide; Conditioning, Psychological; Diazepam; Fear; Male; Mice; Motor Activity; Piperazines; Pyrazoles | 1985 |
Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Central Nervous System; Cerebellum; Corpus Striatum; Diazepam; Flunitrazepam; Frontal Lobe; Hippocampus; Male; Piperazines; Rats; Rats, Inbred Strains; Serotonin; Synaptic Transmission | 1986 |
Behavioral effects of zopiclone, CL 218,872 and diazepam in squirrel monkeys: antagonism by Ro 15-1788 and CGS 8216.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepinones; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Male; Piperazines; Pyrazoles; Pyridazines; Saimiri | 1986 |
A new method for screening anxiolytic drugs in rats.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Azabicyclo Compounds; Diazepam; Drug Evaluation, Preclinical; Flumazenil; Male; Models, Psychological; Piperazines; Rats; Rats, Inbred WKY | 1987 |
Discriminative-stimulus effects of midazolam in squirrel monkeys: comparison with other drugs and antagonism by Ro 15-1788.
Topics: Animals; Azabicyclo Compounds; Barbital; Benzodiazepines; Benzodiazepinones; Buspirone; Caffeine; Chlordiazepoxide; Cinanserin; Clozapine; Conditioning, Operant; Cyproheptadine; Diazepam; Diphenhydramine; Discrimination Learning; Electroshock; Flumazenil; Male; Midazolam; Muscimol; Nordazepam; Pentobarbital; Piperazines; Pyridazines; Pyrimidines; Saimiri; Tripelennamine | 1985 |
Multiple benzodiazepine receptors: evidence of dissociation between anticonflict and anticonvulsant properties by PK 8165 and PK 9084 (two quinoline derivatives).
Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Binding, Competitive; Cerebellar Cortex; Chlordiazepoxide; Conflict, Psychological; Cyclic AMP; Cyclic GMP; Diazepam; Hypnotics and Sedatives; Kinetics; Male; Motor Activity; Piperazines; Quinolines; Rats; Receptors, Drug; Receptors, GABA-A | 1981 |
Brain receptors and zopiclone.
Topics: Animals; Azabicyclo Compounds; Binding, Competitive; Brain; Cerebellum; Chlordiazepoxide; Diazepam; Flunitrazepam; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Male; Mice; Nitrazepam; Piperazines; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1983 |
Brain receptors and zopiclone.
Topics: Animals; Azabicyclo Compounds; Barbiturates; Binding, Competitive; Brain; Chlordiazepoxide; Cyclic GMP; Diazepam; Flunitrazepam; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Male; Piperazines; Rats; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A | 1982 |
Dependence studies on zopiclone.
Topics: Animals; Azabicyclo Compounds; Barbiturates; Behavior, Animal; Diazepam; Humans; Hypnotics and Sedatives; Injections, Intravenous; Intubation, Gastrointestinal; Macaca fascicularis; Macaca mulatta; Piperazines; Self Administration; Substance Withdrawal Syndrome; Substance-Related Disorders | 1983 |
Dependence potential of zopiclone studied in monkeys.
Topics: Administration, Oral; Animals; Azabicyclo Compounds; Barbital; Behavior, Animal; Diazepam; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Macaca fascicularis; Macaca mulatta; Male; Piperazines; Self Administration; Substance-Related Disorders | 1983 |
Dependence potential of zopiclone studied in monkeys.
Topics: Administration, Oral; Animals; Azabicyclo Compounds; Barbital; Diazepam; Female; Humans; Hypnotics and Sedatives; Infusions, Parenteral; Macaca fascicularis; Macaca mulatta; Male; Nitrazepam; Piperazines; Self Administration; Substance Withdrawal Syndrome; Substance-Related Disorders | 1982 |
Sedative and anxiolytic effects of zopiclone's enantiomers and metabolite.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Azabicyclo Compounds; Diazepam; Dose-Response Relationship, Drug; Electroshock; Hypnotics and Sedatives; Isomerism; Male; Motor Activity; Motor Skills; Piperazines; Rats; Rats, Long-Evans; Seizures | 2001 |
[A case of primary zopiclone dependence].
Topics: Anti-Anxiety Agents; Attention; Azabicyclo Compounds; Depression; Diazepam; Female; Humans; Hypnotics and Sedatives; Middle Aged; Piperazines; Substance-Related Disorders | 2001 |
Stereoselective discriminative stimulus effects of zopiclone in rhesus monkeys.
Topics: Administration, Oral; Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; GABA-A Receptor Antagonists; Macaca mulatta; Male; Midazolam; Piperazines; Stereoisomerism; Substance Withdrawal Syndrome | 2003 |
Effects of benzodiazepines receptor agonists on the hypothalamic-pituitary-adrenocortical axis.
Topics: Adrenocorticotropic Hormone; Animals; Azabicyclo Compounds; Carbolines; Corticosterone; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Fluorobenzenes; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; Hypothalamo-Hypophyseal System; Male; Mice; Mice, Inbred Strains; Models, Biological; Paraventricular Hypothalamic Nucleus; Piperazines; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Pyridines; Radioimmunoassay; Receptors, GABA-A; Triazoles; Zolpidem | 2005 |
The detection of sedatives in hair and nail samples using tandem LC-MS-MS.
Topics: Adult; Aged; Aged, 80 and over; Alprazolam; Azabicyclo Compounds; Benzodiazepines; Chromatography, Liquid; Clobazam; Clonazepam; Diazepam; Female; Forensic Pathology; Hair; Humans; Hypnotics and Sedatives; Male; Mass Spectrometry; Midazolam; Middle Aged; Nails; Oxazepam; Piperazines; Predictive Value of Tests; Rape; Temazepam; Triazolam | 2007 |
Concentrations of zolpidem and zopiclone in venous blood samples from impaired drivers compared with femoral blood from forensic autopsies.
Topics: Adult; Aged; Automobile Driving; Azabicyclo Compounds; Central Nervous System Depressants; Chromatography, Gas; Diazepam; Ethanol; Female; Forensic Toxicology; Humans; Hypnotics and Sedatives; Male; Middle Aged; Piperazines; Pyridines; Substance-Related Disorders; Zolpidem | 2012 |
Associations of Benzodiazepines, Z-Drugs, and Other Anxiolytics With Subsequent Dementia in Patients With Affective Disorders: A Nationwide Cohort and Nested Case-Control Study.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Azabicyclo Compounds; Benzodiazepines; Bipolar Disorder; Case-Control Studies; Comorbidity; Dementia; Denmark; Depressive Disorder; Depressive Disorder, Major; Diazepam; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Incidence; Logistic Models; Male; Middle Aged; Mood Disorders; Odds Ratio; Oxazepam; Piperazines; Proportional Hazards Models; Protective Factors; Risk Factors | 2020 |
Development and Validation of an LC-MS-MS Method for the Detection of 40 Benzodiazepines and Three Z-Drugs in Blood and Urine by Solid-Phase Extraction.
Topics: Alprazolam; Azabicyclo Compounds; Benzodiazepines; Chromatography, Liquid; Diazepam; Forensic Toxicology; Humans; Hypnotics and Sedatives; Limit of Detection; Piperazines; Sleep Aids, Pharmaceutical; Solid Phase Extraction; Substance Abuse Detection; Tandem Mass Spectrometry; Zolpidem | 2020 |