Page last updated: 2024-08-16

zonisamide and olanzapine

zonisamide has been researched along with olanzapine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Shelton, RC1
Bymaster, FP; Cowley, MA; Gadde, KM; Krishnan, RK; Landbloom, RP; McKinney, AA; Sinnayah, P; Tollefson, GD; Wallingford, NM1
Case, M; Hoffmann, VP; Jacobson, JG1
Guerdjikova, AI; Keck, PE; Martens, B; McCoy, J; McElroy, SL; Moeller, D; Mori, N; Winstanley, E1
Cowley, MA; Oldfield, BJ; Stefanidis, A; Watt, MJ1

Reviews

2 review(s) available for zonisamide and olanzapine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Treating bipolar depression.
    The Journal of family practice, 2003, Volume: Suppl

    Topics: Acetates; Affect; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium Compounds; Nipecotic Acids; Olanzapine; Oxcarbazepine; Pirenzepine; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide

2003

Trials

2 trial(s) available for zonisamide and olanzapine

ArticleYear
Assessment of treatment algorithms including amantadine, metformin, and zonisamide for the prevention of weight gain with olanzapine: a randomized controlled open-label study.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:2

    Topics: Adolescent; Adult; Aged; Algorithms; Amantadine; Antipsychotic Agents; Benzodiazepines; Clinical Protocols; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Isoxazoles; Male; Metformin; Middle Aged; Olanzapine; Psychotic Disorders; Schizophrenia; Weight Gain; Zonisamide

2012
A randomized, placebo-controlled study of zonisamide to prevent olanzapine-associated weight gain.
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:2

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Cognition Disorders; Double-Blind Method; Female; Follow-Up Studies; Humans; Isoxazoles; Male; Middle Aged; Olanzapine; Regression Analysis; Schizophrenia; Treatment Outcome; Weight Gain; Young Adult; Zonisamide

2012

Other Studies

5 other study(ies) available for zonisamide and olanzapine

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12

    Topics: Animals; Anticonvulsants; Appetite Regulation; Benzodiazepines; Biomarkers; Body Weight; Diabetes Mellitus; Female; Hyperglycemia; Hyperphagia; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Isoxazoles; Neurons; Neuropeptides; Nucleus Accumbens; Obesity; Olanzapine; Orexins; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Weight Gain; Zonisamide

2008
Prevention of the adverse effects of olanzapine on lipid metabolism with the antiepileptic zonisamide.
    Neuropharmacology, 2017, Sep-01, Volume: 123

    Topics: Adiposity; Animals; Antioxidants; Antipsychotic Agents; Benzodiazepines; Body Weight; Drug Therapy, Combination; Eating; Female; Glucose; Homeostasis; Isoxazoles; Lipid Metabolism; Lipolysis; Motor Activity; Olanzapine; Oxygen Consumption; Random Allocation; Rats, Sprague-Dawley; Triglycerides; Zonisamide

2017