Page last updated: 2024-08-16

zomepirac and pyrroles

zomepirac has been researched along with pyrroles in 118 studies

Research

Studies (118)

TimeframeStudies, this research(%)All Research%
pre-1990118 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gussin, RZ; Migdalof, BH; O'Neill, PJ; Yorgey, KA1
Heidrich, G; Houde, RW; Kaiko, RF; Rogers, A; Wallenstein, SL2
Ng, KT; Snyderman, T1
Campbell, RL; Giglio, JA1
Ellis, E; Scott, R; Upton, LG1
Anderson, RE; Hansen, RB; Stevens, MK; Yaksh, TL1
Corre, KA; Spielberg, TE1
Carson, JL; Morse, ML; Soper, KA; Strom, BL; West, SL1
Laska, EM; Marrero, I; McCormick, N; Olson, N; Sunshine, A1
Biron, P1
Hattori, T; Kawai, K; Kurita, K; Shimogo, K; Sugiura, M1
Cater, M; O'Brien, PM; Pickvance, NJ1
Bander, SJ1
Benet, LZ; McDonagh, AF; Smith, PC1
Sandler, RH1
Bullingham, RE; Carroll, D; Collin, J; Evans, PJ; Lloyd, JW; McQuay, HJ; Moore, RA; O'Sullivan, G1
Müller, H; Zulliger, HW1
Graman, HB; Haines, DE; Uphold, RE; Witte, GN1
Joubert, DW1
Aceto, MD; Harris, LS; Jacobson, AE; Medzihradsky, F; Smith, CB; Woods, JH; Young, AM1
Inman, WH; Rawson, NS1
Paulus, HE1
Dunn, GL; Fargas-Babjak, AM; Goldsmith, CH; Morison, DH1
Jefferson, WL; Steele, CE1
Lacher, JW; Miller, FC; Schorr, WJ1
Moretti, B; Patella, V; Pesce, V; Pipino, F1
Gardocki, JF; Muschek, LD; Pruss, TP; Taylor, RJ1
Gross, JI; Vogel, RI1
Akamine, A; Aono, M; Haraga, Y; Honda, N; Kaida, H; Kishi, T; Maeda, K; Nagamine, N; Onimura, K; Yamamoto, J1
Harvengt, C1
Ochoa, JL; Schady, W; Torebjörk, HE1
Lumry, WR; Pleskow, WW; Simon, RA1
Levy, DB; Vasilomanolakis, EC1
Schady, W; Torebjörk, HE1
Schütz, H; Suphachearabhan, S1
Lupo, G; Mirisola, F1
Cohn, P; Cooper, SA; Dyer, C; Gelb, S; Goldman, E1
Hagiwara, S; Ishikawa, I; Kinoshita, S; Kowashi, Y; Miyagawa, M; Noguchi, T; Uraguchi, R; Yamazaki, M1
Benet, LZ; Hasegawa, J; Langendijk, PN; Smith, PC1
Ahmad, S1
Vandemark, RM1
Affrime, MB; Lowenthal, DT; O'Neill, PJ; Pritchard, JF1
Kalbron, JJ; Ng, KT1
Amankwa, L; Chatten, LG; Pons, S1
Agulló García, M; Amador Barciela, L; Llinares Mondéjar, P; Martínez Debén, F; Sesma Sánchez, P; Suárez Sambade, D1
Imazu, C; Ishii, K; Kadokawa, T; Nakamura, H; Shimizu, M; Yokoyama, Y1
Botha, JJ; Weich, DJ1
Cesario, T; Darwish, R; Gupta, S; Licorish, K; Novey, H; Powers, D; Spear, GS; Vaziri, ND1
Creasy, GW; Kousen, M; Walker, WR1
Grindel, JM; Muschek, LD1
Forrest, WH2
Honig, WJ1
Valdez, EV1
Boike, SC; Rybak, MJ; Tintinalli, JE; Veneri, R1
Lisker, WH1
Grindel, JM; Hills, JF; Renzi, NL1
Kiani, R; Kushner, M1
Jacobs, RL; Rake, GW1
Mosley, C; Warren, SE1
Hannaway, PJ; Hopper, GD1
Guerrero, MM1
Dunn, GL; Fargas-Babjak, AM; Morison, DH1
De Castro, A; De Sarrazin, C; Laska, EM; Olson, NZ; Sunshine, A; Zighelboim, I1
Calatroni, A; Pietta, P1
Jasinski, DR; Johnson, RE; Kocher, TR1
Gever, LN1
Romankiewicz, JA1
Di Giacobbe, D; Duplat, JP1
Hilleman, DE1
Aoki, K; Ito, H; Naganawa, Y; Oda, H; Onishi, M1
Braun, H1
Abe, M; Igarashi, K; Mizutani, H; Takagi, R; Takahashi, N1
Samuel, SA1
Ratner, SJ1
Imazu, C; Ishii, K; Motoyoshi, S; Nakamura, H; Seto, Y; Shimizu, M; Yokoyama, Y1
Cooper, SA1
Baird, WM; Turek, D1
Stambaugh, JE; Tejada, F; Trudnowski, RJ1
Joy, ED; Mehlisch, DR; Moore, TE; Porter, K; Stumpf, AJ; Wolfe, SH1
Harbert, G; Messer, RH; Vaughn, T1
Mayer, TG; Ruoff, GE1
Ciccone, WJ; deAndrade, JR; Honig, S; Leffall, L1
Diamond, S1
Bernard, A; Elbaz, JS1
Joy, ED; Mehlisch, DR1
Diamond, S; Medina, JL1
McEvoy, GK1
Honig, S; Murray, KA1
Avery, GS; Brogden, RN; Carmine, AA; Heel, RC; Morley, PA; Speight, TM1
Budoff, PW1
van Thiel, D2
Bullingham, RE; Evans, PJ; McQuay, HJ; Moore, RA; O'Sullivan, G; Rolfe, M1
Gorder, JW1
Smith, VT1
Annesley, TM; Luthra, HS; Moyer, TP; Welch, CL1
Friedman, CJ; Lesnefsky, EJ; Ross, SR1
Blair, TJ; McCarthy, JT; Pierides, AM; Schwartz, GL; Van den Berg, CJ1
Corre, KA; Rothstein, RJ1
Theron, F1
Ellsworth, AJ; Killen, PD; Mease, PJ; Willkens, RF1
Dettwiler, M; Jeger, A; Rippstein, S1
Blackshear, JL1
Kadokawa, T; Motoyoshi, S; Nakamura, H; Seto, Y; Shimizu, M; Yokoyama, Y1
Spector, R1
Benet, LZ; O'Neill, PJ; Renzi, NL; Williams, RL; Yorgey, KA1
O'Neill, PJ1
Hook, JB; Moore, GK; Noordewier, B; O'Neill, PJ; Yorgey, KA1
McKown, LA; O'Neill, PJ; Yorgey, KA1
Affarah, HB; Fellner, SK; Wolfe, C1
Gottlieb, S; Nayak, RK; Ng, KT; Plostnieks, J1
Anderson, NG; Carson, JR1

Reviews

3 review(s) available for zomepirac and pyrroles

ArticleYear
Review of the pharmacokinetics and metabolism of zomepirac in man and animals.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Analgesics; Animals; Biological Availability; Haplorhini; Humans; Kinetics; Mice; Protein Binding; Pyrroles; Rats; Species Specificity; Time Factors; Tolmetin

1980
Evaluation of zomepirac sodium.
    American journal of hospital pharmacy, 1981, Volume: 38, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Costs and Cost Analysis; Drug Interactions; Drug Tolerance; Humans; Kinetics; Pyrroles; Substance-Related Disorders; Tolmetin

1981
Zomepirac: a review of its pharmacological properties and analgesic efficacy.
    Drugs, 1982, Volume: 23, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; Humans; Kinetics; Pain; Pyrroles; Substance-Related Disorders; Tolmetin

1982

Trials

35 trial(s) available for zomepirac and pyrroles

ArticleYear
Comparison of etodolac, zomepirac, and placebo for relief of pain after oral surgery.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1986, Volume: 44, Issue:10

    Topics: Acetates; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Etodolac; Female; Humans; Male; Middle Aged; Molar, Third; Pain, Postoperative; Placebos; Pyrroles; Random Allocation; Time Factors; Tolmetin; Tooth Extraction

1986
Double-blind evaluation of etodolac (200 mg, 400 mg) compared with zomepirac (100 mg) and placebo on third molar extraction pain.
    Oral surgery, oral medicine, and oral pathology, 1986, Volume: 62, Issue:6

    Topics: Acetates; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Etodolac; Humans; Middle Aged; Molar, Third; Pain Measurement; Pain, Postoperative; Pyrroles; Random Allocation; Tolmetin; Tooth Extraction

1986
Comparative study of flurbiprofen, zomepirac sodium, acetaminophen plus codeine, and acetaminophen for the relief of postsurgical dental pain.
    The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A

    Topics: Acetaminophen; Adult; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Flurbiprofen; Humans; Male; Pain, Postoperative; Placebos; Propionates; Pyrroles; Tolmetin; Tooth Extraction

1986
[McN-2783 for pain following the extraction of impacted wisdom tooth--clinical evaluation].
    Shikai tenbo = Dental outlook, 1985, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Molar, Third; Pain, Postoperative; Pyrroles; Tolmetin; Tooth Extraction; Tooth, Impacted

1985
A double-blind comparison of the new ibuprofen-codeine phosphate combination, zomepirac, and placebo in the relief of postepisiotomy pain.
    Clinical therapeutics, 1985, Volume: 7, Issue:4

    Topics: Adult; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Episiotomy; Female; Humans; Ibuprofen; Pain, Postoperative; Pyrroles; Random Allocation; Time Factors; Tolmetin

1985
Zomepirac, dihydrocodeine and placebo compared in postoperative pain after day-case surgery. The relationship between the effects of single and multiple doses.
    British journal of anaesthesia, 1985, Volume: 57, Issue:4

    Topics: Administration, Oral; Adult; Ambulatory Surgical Procedures; Analgesics; Codeine; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; Middle Aged; Pain, Postoperative; Pyrroles; Tolmetin

1985
A comparison of zomepirac and codeine as analgesic premedicants in short-stay surgery.
    Anesthesiology, 1983, Volume: 58, Issue:3

    Topics: Adolescent; Adult; Analgesics; Anesthesia, Dental; Clinical Trials as Topic; Codeine; Double-Blind Method; Humans; Laparoscopy; Middle Aged; Pain, Postoperative; Preanesthetic Medication; Pyrroles; Sterilization, Reproductive; Tolmetin

1983
A multi-centre study of zomepirac in painful conditions: an analysis of clinical data for 15,484 patients.
    Current medical research and opinion, 1983, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Aged; Back Pain; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain; Pyrroles; Sleep; Tolmetin

1983
[Evaluation of the analgesic activity of zomepirac sodium on sciatica and lower back pain].
    Bollettino chimico farmaceutico, 1984, Volume: 123, Issue:1

    Topics: Adult; Aged; Analgesics; Back Pain; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Methimazole; Middle Aged; Pyrroles; Random Allocation; Sciatica; Tolmetin

1984
[A preliminary study on the effective dose and safety of zomepirac sodium. Pain following minor surgery and tooth extraction in the field of dentistry].
    Nihon Shishubyo Gakkai kaishi, 1983, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Humans; Mefenamic Acid; Middle Aged; Mouth; Pain, Postoperative; Pyrroles; Tolmetin; Tooth Extraction

1983
Comparative efficacy of fenoprofen calcium and zomepirac sodium in postsurgical dental pain.
    Oral surgery, oral medicine, and oral pathology, 1984, Volume: 57, Issue:5

    Topics: Adult; Analgesics; Anti-Inflammatory Agents; Evaluation Studies as Topic; Female; Fenoprofen; Humans; Male; Pain, Postoperative; Phenylpropionates; Placebos; Pyrroles; Time Factors; Tolmetin; Tooth Extraction; Tooth, Impacted

1984
Orally administered zomepirac and parenterally administered morphine. Comparison for the treatment of postoperative pain.
    JAMA, 1980, Nov-21, Volume: 244, Issue:20

    Topics: Acute Disease; Administration, Oral; Adult; Cyclooxygenase Inhibitors; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Morphine; Pain, Postoperative; Pyrroles; Tolmetin

1980
Zomepirac as an analgesic premedication: a comparison of three dosage regimens.
    Canadian Anaesthetists' Society journal, 1983, Volume: 30, Issue:4

    Topics: Adult; Analgesics; Anesthesia, General; Double-Blind Method; Drug Administration Schedule; Female; Humans; Pain, Postoperative; Premedication; Pyrroles; Random Allocation; Sterilization, Tubal; Time Factors; Tolmetin

1983
Ibuprofen, zomepirac, aspirin, and placebo in the relief of postepisiotomy pain.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aspirin; Episiotomy; Female; Humans; Ibuprofen; Pain, Postoperative; Placebos; Pyrroles; Tolmetin

1983
Abuse potential of zomepirac.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:3

    Topics: Blood Pressure; Drug Evaluation; Euphoria; Humans; Morphine; Pupil; Pyrroles; Substance-Related Disorders; Surveys and Questionnaires; Tolmetin

1983
Proceedings of the symposium: Zomepirac: a New Non-narcotic Analgesic, held in Atlanta, Georgia on October 12 and 13, 1979.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4 Pt 2

    Topics: Analgesics; Animals; Clinical Trials as Topic; Humans; Pyrroles; Tolmetin

1980
Efficacy of zomepirac in oral surgical pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adult; Analgesics; Aspirin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Male; Mouth; Pain, Postoperative; Placebos; Pyrroles; Time Factors; Tolmetin

1980
Comparison of zomepirac, APC with codeine, codeine and placebo in the treatment of moderate and severe postoperative pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adult; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Female; Humans; Male; Pain, Postoperative; Phenacetin; Placebos; Pyrroles; Time Factors; Tolmetin

1980
Relative analgesic potency of oral zomepirac and intramuscular morphine in cancer patients with postoperative pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Administration, Oral; Adult; Analgesics; Clinical Trials as Topic; Female; Humans; Injections, Intramuscular; Male; Morphine; Neoplasms; Pain, Postoperative; Pyrroles; Tolmetin

1980
Oral zomepirac and intramuscular morphine in postoperative pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Administration, Oral; Analgesics; Clinical Trials as Topic; Double-Blind Method; Humans; Injections, Intramuscular; Morphine; Pain, Postoperative; Pyrroles; Time Factors; Tolmetin

1980
Double-blind comparisons of zomepirac and oxycodone with APC in cancer pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adult; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Neoplasms; Oxycodone; Pain; Phenacetin; Pyrroles; Tolmetin

1980
Clinical comparison of zomepirac with APC/codeine combination in the treatment of pain following oral surgery.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adult; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Female; Humans; Male; Mouth; Pain, Postoperative; Phenacetin; Pyrroles; Tolmetin

1980
Clinical evaluation of zomepirac and APC with codeine in the treatment of postpartum episiotomy pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adult; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Episiotomy; Female; Humans; Pain, Postoperative; Phenacetin; Pyrroles; Tolmetin

1980
Clinical evaluation of zomepirac in the treatment of acute orthopedic pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adult; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Pain; Phenacetin; Pyrroles; Tolmetin; Wounds and Injuries

1980
Clinical comparison of zomepirac with pentazocine in the treatment of postoperative pain.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Analgesics; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Heart Rate; Humans; Pain, Postoperative; Pentazocine; Pyrroles; Tolmetin

1980
Zomepirac in the symptomatic treatment of muscle contraction headache.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adult; Analgesics; Clinical Trials as Topic; Female; Headache; Humans; Male; Middle Aged; Muscle Contraction; Pyrroles; Tolmetin

1980
A controlled repeat-dose comparison of zomepirac and clometacin in pain after plastic surgery.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Aged; Analgesics; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indoleacetic Acids; Male; Middle Aged; Pain, Postoperative; Pyrroles; Surgery, Plastic; Time Factors; Tolmetin

1980
Zomepirac sodium -- a new oral analgesic.
    The Medical letter on drugs and therapeutics, 1981, Jan-09, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Codeine; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Pain; Placebos; Pyrroles; Tolmetin

1981
Zomepirac sodium vs APC with codeine for oral surgery pain.
    Journal of oral surgery (American Dental Association : 1965), 1981, Volume: 39, Issue:6

    Topics: Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Humans; Mouth; Pain, Postoperative; Phenacetin; Pyrroles; Tolmetin

1981
A double-blind study of zomepirac sodium and placebo in the treatment of muscle contraction headache.
    Headache, 1981, Volume: 21, Issue:2

    Topics: Adult; Analgesics; Clinical Trials as Topic; Double-Blind Method; Female; Headache; Humans; Male; Muscle Contraction; Pyrroles; Tolmetin

1981
Postsurgical pain: zomepirac sodium, propoxyphene/-acetaminophen combination, and placebo.
    Journal of clinical pharmacology, 1981, Volume: 21, Issue:10

    Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Pain, Postoperative; Placebos; Pyrroles; Tolmetin

1981
Zomepirac sodium in the treatment of primary dysmenorrhea syndrome.
    The New England journal of medicine, 1982, Sep-16, Volume: 307, Issue:12

    Topics: Activities of Daily Living; Adolescent; Adult; Analgesics; Clinical Trials as Topic; Double-Blind Method; Dysmenorrhea; Female; Humans; Prostaglandin Antagonists; Pyrroles; Research Design; Tolmetin

1982
[An analgesic opens new therapeutic possibilities].
    Therapie der Gegenwart, 1982, Volume: 121, Issue:7

    Topics: Analgesics; Clinical Trials as Topic; Double-Blind Method; Humans; Pain; Pyrroles; Tolmetin

1982
Zomepirac, placebo and paracetamol/dextropropoxyphene combination compared in orthopaedic postoperative pain.
    British journal of anaesthesia, 1982, Volume: 54, Issue:9

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Bone and Bones; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Female; Humans; Male; Middle Aged; Pain, Postoperative; Placebos; Pyrroles; Tolmetin

1982
The intra-uterine contraceptive device -- an attempt to prevent pain and expulsion with zomepirac sodium.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Jun-12, Volume: 61, Issue:24

    Topics: Adolescent; Adult; Analgesics; Double-Blind Method; Female; Follow-Up Studies; Humans; Intrauterine Device Expulsion; Intrauterine Devices, Copper; Pain; Pyrroles; Tolmetin

1982

Other Studies

80 other study(ies) available for zomepirac and pyrroles

ArticleYear
Renal handling of zomepirac sodium (McN-2783-21-98) in the rat.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 209, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chlorobenzoates; Drug Interactions; Half-Life; Hydrogen-Ion Concentration; Kidney; Kinetics; Male; Metabolic Clearance Rate; Probenecid; Pyrroles; Rats; Tolmetin; Urine

1979
Clinical analgesic assay of oral zomepirac and intramuscular morphine.
    NIDA research monograph, 1979, Volume: 27

    Topics: Administration, Oral; Affect; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Humans; Morphine; Pain; Pain, Postoperative; Pyrroles; Research Design; Tolmetin

1979
Determination of zomepirac in plasma by high-pressure liquid chromatography.
    Journal of chromatography, 1979, Oct-19, Volume: 178, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Microchemistry; Pyrroles; Tolmetin

1979
Effect of preischemia cyclooxygenase inhibition by zomepirac sodium on reflow, cerebral autoregulation, and EEG recovery in the cat after global ischemia.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1986, Volume: 6, Issue:6

    Topics: Animals; Brain; Cats; Cerebrovascular Circulation; Cyclooxygenase Inhibitors; Electroencephalography; Female; Homeostasis; Ischemic Attack, Transient; Male; Prostaglandins; Pyrroles; Tolmetin

1986
Adverse drug reaction processing in the United States and its dependence on physician reporting: zomepirac (Zomax) as a case in point.
    Annals of emergency medicine, 1988, Volume: 17, Issue:2

    Topics: Algorithms; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Drug Information Services; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Evaluation Studies as Topic; Humans; Physician's Role; Product Surveillance, Postmarketing; Pyrroles; Role; Tolmetin; United States; United States Food and Drug Administration

1988
The effect of indication on hypersensitivity reactions associated with zomepirac sodium and other nonsteroidal antiinflammatory drugs.
    Arthritis and rheumatism, 1987, Volume: 30, Issue:10

    Topics: Adult; Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Drug Hypersensitivity; Epidemiologic Methods; Female; Florida; Humans; Male; Medicaid; Middle Aged; Online Systems; Pyrroles; Risk Factors; Tolmetin

1987
[Drug surveillance: example of bayesian imputation of an adverse reaction].
    L'union medicale du Canada, 1987, Volume: 116, Issue:2

    Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Bayes Theorem; Female; Humans; Pyrroles; Tolmetin

1987
Reversible renal failure and nephrotic syndrome without interstitial nephritis from zomepirac.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1985, Volume: 6, Issue:4

    Topics: Acute Kidney Injury; Aged; Biopsy; Creatinine; Female; Fluorescent Antibody Technique; Humans; Kidney; Microscopy, Electron; Middle Aged; Nephrosis, Lipoid; Proteinuria; Pyrroles; Tolmetin

1985
Irreversible binding of zomepirac to plasma protein in vitro and in vivo.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:3

    Topics: Blood Proteins; Glucuronates; Humans; Hydrogen-Ion Concentration; Isomerism; Protein Binding; Pyrroles; Serum Albumin; Tolmetin

1986
Anaphylactic reactions to zomepirac.
    Annals of emergency medicine, 1985, Volume: 14, Issue:2

    Topics: Anaphylaxis; Anti-Inflammatory Agents; Female; Humans; Male; Middle Aged; Pyrroles; Tolmetin

1985
Continuous body fluid monitoring for zomepirac by fully automated high-performance liquid chromatography.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:1

    Topics: Analgesics; Body Fluids; Chromatography, High Pressure Liquid; Humans; Pyrroles; Spectrophotometry, Ultraviolet; Tolmetin

1985
Zomepirac-induced anaphylactic shock: an under-reported phenomenon.
    The American journal of the medical sciences, 1985, Volume: 290, Issue:4

    Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents; Female; Humans; Hypotension; Male; Middle Aged; Pyrroles; Tolmetin

1985
Zomepirac overdose and review of literature on acute toxicity of nonsteroidal antiinflammatory agents.
    Drug intelligence & clinical pharmacy, 1982, Volume: 16, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Bicarbonates; Charcoal; Gastrointestinal Hemorrhage; Humans; Ipecac; Kidney Function Tests; Male; Pyrroles; Tolmetin

1982
Zomepirac: preclinical narcotic abuse liability evaluation.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:2

    Topics: Analgesics, Opioid; Animals; Discrimination, Psychological; Female; Humans; In Vitro Techniques; Macaca mulatta; Male; Mice; Morphine Dependence; Muscle, Smooth; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance-Related Disorders; Tolmetin

1983
Zomepirac and cardiovascular deaths.
    Lancet (London, England), 1983, Oct-15, Volume: 2, Issue:8355

    Topics: Analgesics; Cardiovascular Diseases; Humans; Pyrroles; Tolmetin

1983
Government affairs. FDA Arthritis Advisory Committee Meeting.
    Arthritis and rheumatism, 1983, Volume: 26, Issue:11

    Topics: Anaphylaxis; Drug Evaluation; Humans; Ibuprofen; Palliative Care; Pyrroles; Rheumatic Diseases; Tolmetin

1983
Zomepirac-induced renal failure.
    Archives of internal medicine, 1983, Volume: 143, Issue:6

    Topics: Acute Kidney Injury; Adult; Aged; Arthritis; Back Pain; Body Weight; Coronary Artery Bypass; Creatinine; Female; Headache; Humans; Male; Pain; Postoperative Complications; Pyrroles; Time Factors; Tolmetin

1983
Evaluation of the analgesic properties of zomepirac.
    Journal of clinical pharmacology, 1980, Volume: 20, Issue:4

    Topics: Analgesics; Animals; Cattle; Cyclooxygenase Inhibitors; Drug Interactions; Hindlimb; Humans; In Vitro Techniques; Male; Mice; Morphine; Naloxone; Platelet Aggregation; Pyrroles; Reaction Time; Receptors, Opioid; Substance-Related Disorders; Tolmetin

1980
The effects of nonsteroidal anti-inflammatory analgesics on pain after periodontal surgery.
    Journal of the American Dental Association (1939), 1984, Volume: 109, Issue:5

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Pain, Postoperative; Periodontal Diseases; Placebos; Prospective Studies; Pyrroles; Tolmetin

1984
Drugs recently released in Belgium.
    Acta clinica Belgica, 1983, Volume: 38, Issue:3

    Topics: Analgesics; Belgium; Drug and Narcotic Control; Ergolines; Etidronic Acid; Humans; Lisuride; Minoxidil; Pyrimidines; Pyrroles; Tolmetin

1983
A new method for demonstration of central effects of analgesic agents in man.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:8

    Topics: Adult; Analgesics; Brain; Electric Stimulation; Evoked Potentials; Foot; Hand; Humans; Nerve Fibers; Nociceptors; Peripheral Nerves; Pyrroles; Sensory Thresholds; Tolmetin

1984
Zomepirac sodium (Zomax) hypersensitivity in aspirin-sensitive asthmatics.
    The American review of respiratory disease, 1984, Volume: 130, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aspirin; Asthma; Drug Hypersensitivity; Female; Forced Expiratory Volume; Humans; Middle Aged; Pyrroles; Tolmetin

1984
Anaphylactic reaction due to zomepirac.
    Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:12

    Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents; Humans; Male; Pyrroles; Tolmetin

1984
Central effects of zomepirac on pain evoked by intraneural stimulation in man.
    Journal of clinical pharmacology, 1984, Volume: 24, Issue:10

    Topics: Adolescent; Adult; Double-Blind Method; Electric Stimulation; Humans; Neurons; Pain; Pyrroles; Tolmetin

1984
[Screening and detection of the analgesic zomepirac].
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:3

    Topics: Analgesics; Biotransformation; Chromatography, Gas; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Humans; Mass Spectrometry; Photometry; Pyrroles; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Tolmetin

1984
[Pain reduction in patients undergoing periodontal surgery treated with zomepirac sodium].
    Dental Cadmos, 1983, Volume: 51, Issue:3

    Topics: Adult; Analgesics; Aspirin; Female; Humans; Male; Pain, Postoperative; Periodontal Diseases; Placebos; Pyrroles; Tolmetin

1983
[Evaluation of the analgesic and anti-inflammatory drug "Zomepirac Na" in dental surgical pain].
    Nihon Shishubyo Gakkai kaishi, 1984, Volume: 26, Issue:3

    Topics: Analgesics; Anti-Inflammatory Agents; Dental Care; Double-Blind Method; Drug Evaluation; Humans; Pain, Postoperative; Pyrroles; Tolmetin

1984
Simultaneous determination of zomepirac and its major metabolite zomepirac glucuronide in human plasma and urine.
    Journal of chromatography, 1984, May-11, Volume: 307, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Pyrroles; Spectrophotometry, Ultraviolet; Tolmetin

1984
Severe coronary spasm during zomepirac-induced allergic reaction.
    Southern medical journal, 1984, Volume: 77, Issue:7

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Coronary Vasospasm; Drug Hypersensitivity; Female; Humans; Middle Aged; Pyrroles; Tolmetin

1984
Anaphylactoid reaction to zomepirac.
    Annals of emergency medicine, 1983, Volume: 12, Issue:9

    Topics: Adult; Anaphylaxis; Drug Hypersensitivity; Female; Humans; Pyrroles; Respiratory Insufficiency; Tolmetin

1983
Influence of uremia, hemodialysis, and nonesterified fatty acids on zomepirac plasma protein binding.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:5

    Topics: Adult; Aged; Drug Interactions; Fatty Acids, Nonesterified; Female; Humans; Male; Middle Aged; Protein Binding; Pyrroles; Renal Dialysis; Tolmetin; Uremia

1983
Sensitive gas chromatographic quantitation of zomepirac in plasma using an electron-capture detector.
    Journal of chromatography, 1983, Sep-09, Volume: 276, Issue:2

    Topics: Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Humans; Pyrroles; Tolmetin

1983
Voltammetric studies of zomepirac sodium and its determination in tablets by differential-pulse polarography.
    The Analyst, 1983, Volume: 108, Issue:1289

    Topics: Hydrogen-Ion Concentration; Polarography; Pyrroles; Tablets; Tolmetin

1983
[Nephrogenic diabetes insipidus possibly secondary to the ingestion of sodium zomepirac dihydrate].
    Medicina clinica, 1983, Oct-22, Volume: 81, Issue:12

    Topics: Adult; Diabetes Insipidus; Humans; Male; Pyrroles; Tolmetin

1983
Site of analgesic action of zomepirac sodium, a potent non-narcotic analgesic in experimental animals.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:4

    Topics: Alprostadil; Analgesics; Animals; Ascitic Fluid; Bradykinin; Dogs; Hypertension; Injections, Intraventricular; Male; Naloxone; Pain; Prostaglandins E; Pyrroles; Rats; Rats, Inbred Strains; Tolmetin

1983
Hypersensitivity to non-steroidal anti-inflammatory drugs--asthma precipitated by zomepirac. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Feb-04, Volume: 65, Issue:5

    Topics: Analgesics; Aspirin; Asthma; Humans; Male; Middle Aged; Pyrroles; Time Factors; Tolmetin

1984
Focal renal cortical necrosis associated with zomepirac.
    The American journal of medicine, 1984, Volume: 76, Issue:6

    Topics: Analgesics; Anaphylaxis; Female; Humans; Immunoglobulin E; Kidney Cortex; Kidney Cortex Necrosis; Lymphocyte Activation; Middle Aged; Pyrroles; Tolmetin; Toothache

1984
A zomepirac reaction mimicking ectopic pregnancy.
    Drug intelligence & clinical pharmacy, 1984, Volume: 18, Issue:6

    Topics: Adult; Diagnosis, Differential; Drug Hypersensitivity; Female; Humans; Hypotension; Pain; Pregnancy; Pregnancy, Ectopic; Pyrroles; Rupture, Spontaneous; Tolmetin

1984
[Pain therapy following meniscectomy. Comparison of zomepirac and tilidine].
    MMW, Munchener medizinische Wochenschrift, 1982, Jul-16, Volume: 124, Issue:28

    Topics: Adult; Analgesics; Cyclohexanecarboxylic Acids; Female; Humans; Male; Menisci, Tibial; Pain, Postoperative; Pyrroles; Tilidine; Tolmetin

1982
[Treatment of postoperative pain. Zomepirac, mefenamic acid and placebo].
    MMW, Munchener medizinische Wochenschrift, 1982, Oct-08, Volume: 124, Issue:40

    Topics: Adult; Analgesics; Double-Blind Method; Humans; Mefenamic Acid; Pain, Postoperative; Pyrroles; Random Allocation; Tolmetin

1982
Zomepirac sodium for primary dysmenorrhea syndrome.
    The New England journal of medicine, 1983, Feb-17, Volume: 308, Issue:7

    Topics: Analgesics; Dysmenorrhea; Female; Humans; Pyrroles; Tolmetin

1983
Zomepirac-related acute renal failure.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:1

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents; Female; Humans; Middle Aged; Pyrroles; Tolmetin

1983
Nonoliguric renal failure associated with zomepirac.
    JAMA, 1983, Apr-01, Volume: 249, Issue:13

    Topics: Acute Kidney Injury; Analgesics; Humans; Male; Middle Aged; Oliguria; Pain; Pyrroles; Tolmetin

1983
Reversed-phase high-performance liquid chromatographic assay for zomepirac in urine.
    Journal of chromatography, 1983, Jan-14, Volume: 272, Issue:1

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Humans; Pyrroles; Tolmetin

1983
Zomepirac-induced serum sickness. A report of two cases.
    JAMA, 1983, May-27, Volume: 249, Issue:20

    Topics: Adult; Analgesics; Drug Hypersensitivity; Humans; Male; Middle Aged; Pain; Pyrroles; Serum Sickness; Tolmetin

1983
Anaphylactoid reactions to tolmetin and zomepirac.
    Annals of allergy, 1983, Volume: 50, Issue:5

    Topics: Adult; Anaphylaxis; Humans; Male; Pyrroles; Respiratory Function Tests; Skin Tests; Structure-Activity Relationship; Time Factors; Tolmetin

1983
Renal failure and tubular dysfunction due to zomepirac therapy.
    JAMA, 1983, Jan-21, Volume: 249, Issue:3

    Topics: Acidosis, Renal Tubular; Aged; Analgesics; Female; Humans; Joint Diseases; Kidney Failure, Chronic; Middle Aged; Pain; Pyrroles; Tolmetin

1983
Severe anaphylaxis and drug-induced beta-blockade.
    The New England journal of medicine, 1983, Jun-23, Volume: 308, Issue:25

    Topics: Analgesics; Anaphylaxis; Female; Humans; Male; Middle Aged; Propranolol; Pyrroles; Tolmetin

1983
Anaphylaxis following zomepirac ingestion.
    The Western journal of medicine, 1983, Volume: 138, Issue:4

    Topics: Analgesics; Anaphylaxis; Humans; Male; Middle Aged; Pyrroles; Tolmetin

1983
High-performance liquid chromatographic assay for zomepirac and its main metabolite in urine.
    Journal of chromatography, 1983, Jun-10, Volume: 275, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Microchemistry; Pyrroles; Tolmetin

1983
Zomepirac sodium. Learn about this potent new non-narcotic analgesic.
    Nursing, 1981, Volume: 11, Issue:6

    Topics: Adult; Analgesics; Child; Female; Humans; Male; Pain; Pyrroles; Tolmetin

1981
Nonsteroidal anti-inflammatory agents, Part IV - A new analgesic: zomepirac.
    The Journal of practical nursing, 1982, Volume: 32, Issue:2

    Topics: Analgesics; Humans; Pyrroles; Tolmetin

1982
[Drug knowledge: zomepirac (sodium) (Zomax)].
    L' Infirmiere canadienne, 1982, Volume: 24, Issue:11

    Topics: Adult; Humans; Pain, Postoperative; Pyrroles; Tolmetin

1982
Zomax.
    The Chronicle, 1982, Volume: 45, Issue:2

    Topics: Analgesics; Anti-Inflammatory Agents; Pyrroles; Tolmetin

1982
[Analgesic effects of McN-2783 to post-extraction pain--preliminary test for the determination of proper dosage].
    Shikai tenbo = Dental outlook, 1982, Volume: 59, Issue:1

    Topics: Adolescent; Adult; Analgesics; Drug Evaluation; Female; Humans; Male; Middle Aged; Pain, Postoperative; Pyrroles; Tolmetin; Tooth Extraction

1982
[Zomax--progress in analgesia. A new, non-narcotic analgesic].
    Swiss dent, 1981, Volume: 2, Issue:9

    Topics: Analgesics; Humans; Kinetics; Pain; Pyrroles; Tolmetin

1981
[Analgesic effect of McN-2783 (Zomepirac sodium) for postextraction pain].
    Shikai tenbo = Dental outlook, 1982, Volume: 60, Issue:4

    Topics: Analgesics; Pain, Postoperative; Pyrroles; Tolmetin; Tooth Extraction

1982
Apparent anaphylactic reaction to zomepirac (Zomax)
    The New England journal of medicine, 1981, Apr-16, Volume: 304, Issue:16

    Topics: Adult; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Pyrroles; Tolmetin

1981
Zomepirac (Zomax).
    Drug and therapeutics bulletin, 1982, Apr-16, Volume: 20, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Pyrroles; Tolmetin

1982
Zomepirac and renal failure.
    Annals of internal medicine, 1982, Volume: 96, Issue:6 Pt 1

    Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Humans; Male; Pyrroles; Tolmetin

1982
[Analgesic activity of a non-steroidal antiinflammatory drug, zomepirac sodium, in experimental animals].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Blood Pressure; Bradykinin; Dogs; Edema; Female; Lethal Dose 50; Male; Mice; Pyrroles; Rabbits; Rats; Rats, Inbred Strains; Tolmetin

1982
Nonsteroidal anti-inflammatory: zomepirac sodium.
    Geriatrics, 1982, Volume: 37, Issue:2

    Topics: Aged; Anti-Inflammatory Agents; Humans; Pain; Pyrroles; Tolmetin

1982
Anaphylactic shock, acute renal failure, and disseminated intravascular coagulation. Suspected complications of zomepirac.
    JAMA, 1982, Feb-26, Volume: 247, Issue:8

    Topics: Acute Kidney Injury; Aged; Anaphylaxis; Disseminated Intravascular Coagulation; Humans; Male; Pain; Pyrroles; Tolmetin

1982
Liquid-chromatographic determination of zomepirac in serum and plasma.
    Clinical chemistry, 1982, Volume: 28, Issue:3

    Topics: Adult; Analgesics; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Kinetics; Male; Pyrroles; Tolmetin

1982
Near fatal bronchospasm induced by zomepirac sodium.
    Annals of allergy, 1982, Volume: 48, Issue:4

    Topics: Adult; Aspirin; Bronchial Spasm; Drug Hypersensitivity; Humans; Male; Pyrroles; Tolmetin

1982
Reversible nonoliguric acute renal failure associated with zomepirac therapy.
    Mayo Clinic proceedings, 1982, Volume: 57, Issue:6

    Topics: Acute Kidney Injury; Aged; Analgesics; Creatinine; Female; Humans; Kidney Glomerulus; Pyrroles; Tolmetin

1982
Anaphylactic reaction to zomepirac.
    Annals of allergy, 1982, Volume: 48, Issue:5

    Topics: Analgesics; Anaphylaxis; Anti-Inflammatory Agents; Blood Pressure; Epinephrine; Female; Humans; Hypersensitivity, Immediate; Middle Aged; Pruritus; Pyrroles; Rhinitis, Allergic, Seasonal; Seizures; Tolmetin

1982
[A drug fights pain on two levels].
    Medizinische Klinik (Praxis-Ausg.), 1982, Jun-18, Volume: 77, Issue:13

    Topics: Analgesics; Humans; Nociceptors; Pain; Pyrroles; Tolmetin

1982
Zomepirac, interstitial nephritis, and renal failure.
    Annals of internal medicine, 1982, Volume: 97, Issue:3

    Topics: Acute Kidney Injury; Female; Humans; Male; Middle Aged; Nephritis, Interstitial; Pyrroles; Tolmetin

1982
A rapid sensitive determination of carprofen and zomepirac using thin-layer chromatography and gas chromatography--mass spectrometry.
    Journal of chromatography, 1982, Jul-23, Volume: 244, Issue:1

    Topics: Animals; Carbazoles; Chromatography, Thin Layer; Doping in Sports; Gas Chromatography-Mass Spectrometry; Horses; Pyrroles; Tolmetin

1982
Drug-induced failure.
    Mayo Clinic proceedings, 1982, Volume: 57, Issue:10

    Topics: Acute Kidney Injury; Humans; Pyrroles; Tolmetin

1982
[Anti-inflammatory activity of a non-steroidal anti-inflammatory agent, zomepirac sodium, in experimental animals].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:6

    Topics: Adrenalectomy; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Capillary Permeability; Depression, Chemical; Edema; Guinea Pigs; In Vitro Techniques; Male; Mice; Peptic Ulcer; Prostaglandins; Protein Denaturation; Pyrroles; Rabbits; Rats; Tolmetin

1982
Zomepirac.
    Journal of the Iowa Medical Society, 1982, Volume: 72, Issue:10

    Topics: Analgesics; Double-Blind Method; Humans; Prostaglandin Antagonists; Pyrroles; Tolmetin

1982
Disposition of zomepirac sodium in man.
    Journal of clinical pharmacology, 1982, Volume: 22, Issue:10

    Topics: Adult; Analgesics; Glucuronates; Half-Life; Humans; Hydroxylation; Male; Pyrroles; Time Factors; Tolmetin

1982
Plasma protein binding of zomepirac sodium.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:7

    Topics: Animals; Blood Proteins; Humans; Macaca mulatta; Mice; Protein Binding; Pyrroles; Rats; Salicylates; Species Specificity; Tolmetin; Warfarin

1981
Effects of zomepirac and indomethacin on renal blood flow and electrolyte excretion in anesthetized monkeys.
    Life sciences, 1981, Sep-28, Volume: 29, Issue:13

    Topics: Anesthesia; Animals; Electrolytes; Glomerular Filtration Rate; Indomethacin; Macaca mulatta; Male; Pyrroles; Renal Circulation; Tolmetin

1981
Dose-dependent pharmacokinetics and renal handling of zomepirac in rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 219, Issue:3

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Female; Kidney; Kinetics; Macaca mulatta; Male; Metabolic Clearance Rate; Pyrroles; Tolmetin

1981
Acute renal failure and zomepirac.
    Archives of internal medicine, 1981, Volume: 141, Issue:13

    Topics: Acute Kidney Injury; Adult; Analgesics; Female; Humans; Pyrroles; Tolmetin

1981
Zomepirac kinetics in healthy males.
    Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:3

    Topics: Adult; Analgesics; Dose-Response Relationship, Drug; Humans; Intestinal Absorption; Kidney; Kinetics; Male; Metabolic Clearance Rate; Pyrroles; Tolmetin

1980
Synthesis and biological activity of 5-(4-chlorobenzoyl)-4-(hydroxymethyl)-1-methyl-1H-pyrrole-2-acetic acid, a major metabolite of zomepirac sodium.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:1

    Topics: Analgesics; Animals; Arthritis, Experimental; Humans; In Vitro Techniques; Platelet Aggregation; Pyrroles; Rats; Stomach Ulcer; Tolmetin

1980