Page last updated: 2024-08-16

zomepirac and indomethacin

zomepirac has been researched along with indomethacin in 23 studies

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (30.43)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (21.74)	29.6817
2010's	11 (47.83)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ackerman, N; Ballaron, SA; Galeazzi, E; Greenhouse, R; Guzmán, A; Muchowski, JM; Peréz, V; Rovito, JR; Tomolonis, AJ; Young, JM	1
Bailey, PJ; Dorn, CP; Dougherty, HW; Frankshun, RA; Hagmann, WK; O'Grady, LA; Rackham, A	1
Ackerman, NA; Dunn, JP; Tomolonis, AJ	1
Ackrell, J; Cooper, GF; Halpern, O; Kluge, AF; Koehler, R; Muchowski, JM; Simon, RL; Unger, SH; Van Horn, AR; Wren, DL	1
Dannenburg, WN; Moran, HW; Sancilio, LF; Shamblee, DA; Uwaydah, IM; Walsh, DA; Welstead, WJ	1
Strassburg, CP; Tukey, RH	1
Chang, TK; Ensom, MH; Kiang, TK	1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Board, PG; Christ, AN; Clark, AG; Flanagan, JU; Hall, R; Hayes, JD; Hume, DA; Oakley, AJ; Smythe, ML; Weber, JE	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T	1
Bu, X; Cao, Y; Hu, X; Luo, M; Ren, Y; Song, Y; Wang, X; Xu, Q; Yuan, M	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Cheng, YK; Hu, X; Li, Z; Liu, M; Luo, HB; Yuan, M	1
Kumar, M; Sinha, VR; Thareja, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Court, H; Volans, GN	1
Hook, JB; Moore, GK; Noordewier, B; O'Neill, PJ; Yorgey, KA	1
Atherton, J; Bauman, J; Kohl, C; Lam, W; Lou, Z; Mutlib, A; Reily, M; Walker, GS	1
Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC	1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y	1

Reviews

2 review(s) available for zomepirac and indomethacin

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005

Other Studies

21 other study(ies) available for zomepirac and indomethacin

Article	Year
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-6-(methylthio)-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-ca rboxyl ic acids and 1-methyl-4-(methylthio)-5-aroylpyrrole-2-acetic acids. Journal of medicinal chemistry, 1989, Volume: 32, Issue:6 Topics: Acetates; Analgesia; Animals; Aspirin; Benzoquinones; Carboxylic Acids; Carrageenan; Chemical Phenomena; Chemistry; Edema; Inflammation; Mice; Molecular Structure; Pain Measurement; Phenylbutazone; Pyrroles; Quinones; Rats	1989
Synthesis and antiinflammatory/analgesic activities of 11H-dibenzo[b, e,][1,4]dioxepinacetic acids. Journal of medicinal chemistry, 1986, Volume: 29, Issue:8 Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzoxepins; Edema; Gastrointestinal Hemorrhage; Male; Mice; Pain; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1986
Analgetic and antiinflammatory 7-aroylbenzofuran-5-ylacetic acids and 7-aroylbenzothiophene-5-ylacetic acids. Journal of medicinal chemistry, 1986, Volume: 29, Issue:11 Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Female; Male; Mice; Rats; Structure-Activity Relationship; Thiophenes	1986
Synthesis and antiinflammatory and analgesic activity of 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids. The 6-substituted compounds. Journal of medicinal chemistry, 1987, Volume: 30, Issue:5 Topics: Analgesia; Animals; Carboxylic Acids; Chemical Phenomena; Chemistry; Inflammation; Magnetic Resonance Spectroscopy; Mice; Pyrroles; Rats; Structure-Activity Relationship	1987
Antiinflammatory agents. 3. Synthesis and pharmacological evaluation of 2-amino-3-benzoylphenylacetic acid and analogues. Journal of medicinal chemistry, 1984, Volume: 27, Issue:11 Topics: Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Female; Indomethacin; Intestines; Isomerism; Male; Phenylacetates; Rats; Rats, Inbred Strains; Stomach	1984
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach. Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7 Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D2 synthase. European journal of medicinal chemistry, 2010, Volume: 45, Issue:2 Topics: Binding Sites; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glutathione Transferase; Hematopoiesis; Humans; Intramolecular Oxidoreductases; Lipocalins; Models, Molecular; Molecular Conformation; Nocodazole	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney	2011
Identification of curcumin derivatives as human glyoxalase I inhibitors: A combination of biological evaluation, molecular docking, 3D-QSAR and molecular dynamics simulation studies. Bioorganic & medicinal chemistry, 2011, Feb-01, Volume: 19, Issue:3 Topics: Curcumin; Drug Design; Enzyme Inhibitors; Genetic Vectors; Humans; Inhibitory Concentration 50; Lactoylglutathione Lyase; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Molecular Targeted Therapy; Plasmids; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
Structural investigation into the inhibitory mechanisms of indomethacin and its analogues towards human glyoxalase I. Bioorganic & medicinal chemistry letters, 2011, Jul-15, Volume: 21, Issue:14 Topics: Binding Sites; Catalytic Domain; Humans; Indomethacin; Kinetics; Lactoylglutathione Lyase; Molecular Dynamics Simulation; Thermodynamics	2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Poisoning after overdose with non-steroidal anti-inflammatory drugs. Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin	1984
Effects of zomepirac and indomethacin on renal blood flow and electrolyte excretion in anesthetized monkeys. Life sciences, 1981, Sep-28, Volume: 29, Issue:13 Topics: Anesthesia; Animals; Electrolytes; Glomerular Filtration Rate; Indomethacin; Macaca mulatta; Male; Pyrroles; Renal Circulation; Tolmetin	1981
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy. Chemical research in toxicology, 2007, Volume: 20, Issue:6 Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin	2007
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs. Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts	2012
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3. PloS one, 2012, Volume: 7, Issue:8 Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin	2012