Page last updated: 2024-08-16

zomepirac and ibuprofen

zomepirac has been researched along with ibuprofen in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199011 (45.83)18.7374
1990's0 (0.00)18.2507
2000's5 (20.83)29.6817
2010's7 (29.17)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Chang, TK; Ensom, MH; Kiang, TK1
Anacardio, R; Aureli, L; Cesta, MC; Cruciani, G; De Simone, L; Moriconi, A1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Kumar, M; Sinha, VR; Thareja, S1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Kalgutkar, AS1
Kunitake, LM; Pallasch, TJ1
Cater, M; O'Brien, PM; Pickvance, NJ1
Paulus, HE1
Gross, JI; Vogel, RI1
Bergman, SA; Crossley, HL; Wynn, RL1
Cooper, SA2
Bender, WL; Beschorner, WE; Darwish, MO; Hall-Craggs, M; Solez, K; Whelton, A1
Court, H; Volans, GN1
De Castro, A; De Sarrazin, C; Laska, EM; Olson, NZ; Sunshine, A; Zighelboim, I1
Haire, WD1
Atherton, J; Bauman, J; Kohl, C; Lam, W; Lou, Z; Mutlib, A; Reily, M; Walker, GS1
Unlü, B; van Leeuwen, JS; Vermeulen, NP; Vos, JC1
Chai, MZ; Flanagan, JU; Squire, CJ; Teague, RM; Turnbull, AP; Yosaatmadja, Y1

Reviews

4 review(s) available for zomepirac and ibuprofen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
Nonsteroidal anti-inflammatory agents in relieving dental pain: a review.
    Journal of the American Dental Association (1939), 1983, Volume: 106, Issue:1

    Topics: Analgesics; Anti-Inflammatory Agents; Chemical Phenomena; Chemistry; Drug Interactions; Humans; Ibuprofen; Kinetics; Mouth; Pain, Postoperative; Tolmetin

1983
New peripherally-acting oral analgesic agents.
    Annual review of pharmacology and toxicology, 1983, Volume: 23

    Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diflunisal; Humans; Ibuprofen; Indoprofen; Naproxen; Pain; Pain, Postoperative; Tolmetin

1983

Trials

3 trial(s) available for zomepirac and ibuprofen

ArticleYear
A double-blind comparison of the new ibuprofen-codeine phosphate combination, zomepirac, and placebo in the relief of postepisiotomy pain.
    Clinical therapeutics, 1985, Volume: 7, Issue:4

    Topics: Adult; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Episiotomy; Female; Humans; Ibuprofen; Pain, Postoperative; Pyrroles; Random Allocation; Time Factors; Tolmetin

1985
New peripherally-acting oral analgesic agents.
    Annual review of pharmacology and toxicology, 1983, Volume: 23

    Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials as Topic; Diflunisal; Humans; Ibuprofen; Indoprofen; Naproxen; Pain; Pain, Postoperative; Tolmetin

1983
Ibuprofen, zomepirac, aspirin, and placebo in the relief of postepisiotomy pain.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Aspirin; Episiotomy; Female; Humans; Ibuprofen; Pain, Postoperative; Placebos; Pyrroles; Tolmetin

1983

Other Studies

18 other study(ies) available for zomepirac and ibuprofen

ArticleYear
Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.
    Journal of medicinal chemistry, 2005, Apr-07, Volume: 48, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Chemical Phenomena; Chemistry, Physical; Humans; In Vitro Techniques; Interleukin-8; Models, Molecular; Phenylpropionates; Protein Binding; Quantitative Structure-Activity Relationship; Serum Albumin; Stereoisomerism

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
    European journal of medicinal chemistry, 2012, Volume: 53

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Designing around Structural Alerts in Drug Discovery.
    Journal of medicinal chemistry, 2020, 06-25, Volume: 63, Issue:12

    Topics: Drug Design; Drug Development; Drug Discovery; Drug-Related Side Effects and Adverse Reactions; Humans; Molecular Structure; Pharmaceutical Preparations; Structure-Activity Relationship

2020
Nonsteroidal anti-inflammatory analgesics.
    The Compendium of continuing education in dentistry, 1985, Volume: 6, Issue:1

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diflunisal; Drug Interactions; Humans; Ibuprofen; Tolmetin

1985
Government affairs. FDA Arthritis Advisory Committee Meeting.
    Arthritis and rheumatism, 1983, Volume: 26, Issue:11

    Topics: Anaphylaxis; Drug Evaluation; Humans; Ibuprofen; Palliative Care; Pyrroles; Rheumatic Diseases; Tolmetin

1983
The effects of nonsteroidal anti-inflammatory analgesics on pain after periodontal surgery.
    Journal of the American Dental Association (1939), 1984, Volume: 109, Issue:5

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Pain, Postoperative; Periodontal Diseases; Placebos; Prospective Studies; Pyrroles; Tolmetin

1984
Interstitial nephritis, proteinuria, and renal failure caused by nonsteroidal anti-inflammatory drugs. Immunologic characterization of the inflammatory infiltrate.
    The American journal of medicine, 1984, Volume: 76, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Biopsy; Female; Fenoprofen; Fluorescent Antibody Technique; Humans; Ibuprofen; Kidney Diseases; Kidney Glomerulus; Male; Middle Aged; Nephritis, Interstitial; Phenylpropionates; Proteinuria; T-Lymphocytes, Cytotoxic; Tolmetin

1984
Five studies on ibuprofen for postsurgical dental pain.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Codeine; Drug Combinations; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Periodontal Diseases; Surgery, Oral; Tolmetin; Tooth, Impacted

1984
Poisoning after overdose with non-steroidal anti-inflammatory drugs.
    Adverse drug reactions and acute poisoning reviews, 1984,Spring, Volume: 3, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Child; Child, Preschool; Diflunisal; Female; Fenoprofen; Feprazone; Humans; Ibuprofen; Indomethacin; Ketoprofen; London; Male; Mefenamic Acid; Naproxen; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Tolmetin

1984
Hemophilic osteoarthropathy.
    Archives of internal medicine, 1982, Volume: 142, Issue:5

    Topics: Analgesics; Bone Diseases; Hemophilia A; Humans; Ibuprofen; Joint Diseases; Tolmetin

1982
Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
    Chemical research in toxicology, 2007, Volume: 20, Issue:6

    Topics: Acylation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile; Chromatography, Liquid; Cyclooxygenase Inhibitors; Diclofenac; Drug Stability; Flufenamic Acid; Glucuronides; Half-Life; Ibuprofen; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mefenamic Acid; Molecular Structure; Rats; Rats, Sprague-Dawley; Stereoisomerism; Technology, Pharmaceutical; Tolmetin

2007
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; ATP-Binding Cassette Transporters; Biological Transport, Active; Cytochrome P-450 Enzyme System; Diclofenac; Electron Transport; Genes, MDR; Ibuprofen; Indomethacin; Ketoprofen; Ketorolac; Mitochondria; Naproxen; Reactive Oxygen Species; Sulindac; Tolmetin; Yeasts

2012
Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: 3-Hydroxysteroid Dehydrogenases; Aldo-Keto Reductase Family 1 Member C3; Anti-Inflammatory Agents, Non-Steroidal; Flufenamic Acid; Flurbiprofen; Hydroxyprostaglandin Dehydrogenases; Ibuprofen; Indomethacin; Meclofenamic Acid; Mefenamic Acid; Naproxen; Sulindac; Tolmetin

2012