Page last updated: 2024-08-16

zolpidem and triazolam

zolpidem has been researched along with triazolam in 81 studies

Research

Studies (81)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.47)	18.7374
1990's	39 (48.15)	18.2507
2000's	25 (30.86)	29.6817
2010's	14 (17.28)	24.3611
2020's	1 (1.23)	2.80

Authors

Authors	Studies
Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Ator, NA; Brady, JV; Griffiths, RR; Sannerud, CA	1
Arbilla, S; Benavides, J; Durand, A; Peny, B; Scatton, B	1
Coleman, BS; Jonas, JM; Kalinske, RW; Sheridan, AQ	1
Sanger, DJ; Zivkovic, B	1
Balkin, TJ; Belenky, G; McCann, U; O'Donnell, VM; Wesensten, N	1
Cooper, M; Hoffmann, WE; Piercey, MF	1
Critchfield, TS; Evans, SM; Griffiths, RR	1
Evans, SM; Funderburk, FR; Griffiths, RR	1
Aubier, M; Murciano, D; Palacios, S; Pariente, R	1
Evans, SM; Griffiths, RR	1
Joly, D; Sanger, DJ; Zivkovic, B	1
Balkin, TJ; Belenky, GL; Wesensten, NJ	2
Cohen, C; Sanger, DJ	1
Merlotti, L; Roehrs, T; Roth, T; Zorick, F	1
Attali, P; de la Giclais, B; Monti, D; Monti, JM; Morselli, PL; Zipfel, A	1
Ahlstrøm, F; Rosenberg, J	1
Bagot, C; Berlin, I; Hergueta, T; Molinier, P; Puech, AJ; Warot, D	1
Armengaud, MH; Aubier, M; Cramer, PH; L'Héritier, C; Murciano, D; Neveux, E; Pariente, R	1
Balkin, TJ; Belenky, GL; Davis, HQ; Wesensten, NJ	1
Griffiths, RR; Rush, CR	1
Meier-Abt, PJ; Radovanovic, D; Wyss, PA	1
Hadingham, KL; Palmer, KJ; Thompson, SA; Wafford, KA; Whiting, PJ	1
Rowlett, JK; Woolverton, WL	1
Goldman, NH; Madakasira, S; Rowlett, JK; Rush, CR; Woolverton, WL	1
Chapados, R; Chung, FF; Gauthier, M; Knox, JW; Le Lorier, J; Morgan, PJ	1
Roehrs, T; Roth, T; Scharf, MB; Vogel, GW; Walsh, JK; Ware, JC	1
Greene, WL; Lobo, BL	2
Boselli, M; Parrino, L; Smerieri, A; Spaggiari, MC; Terzano, MG	1
Allard, S; Holt, RJ	1
Ali, JA; Armstrong, DL; Pazzaglia, PJ; Rush, CR	1
Frey, JM; Griffiths, RR; Mintzer, MZ; Yingling, JE	1
Frey, JM; Griffiths, RR; Mintzer, MZ	1
Griebel, G; Perrault, G; Sanger, DJ	1
Higuchi, H; Hishikawa, Y; Kamata, M; Shimizu, T; Yoshida, K; Yoshimoto, M	1
Griffiths, RR; Mintzer, MZ	1
Higuchi, H; Hishikawa, Y; Shimizu, T; Takahashi, H; Yoshimoto, M	1
Baker, RW; Rush, CR; Wright, K	1
Carter, RB; Edgar, DM; Fick, DB; Gee, KW; Hogenkamp, DJ; Lan, NC; Seidel, WF; Vanover, KE	1
Berger, M; Feige, B; Hohagen, F; Riemann, D; Voderholzer, U	1
Baker, RW; Rowlett, JK; Rush, CR	1
Durol, AL; Greenblatt, DJ; Harmatz, JS; Harrel-Joseph, LM; Shader, RI; von Moltke, LL; Wright, CE	1
Cevallos, WH; Furlan, PM; Leister, CA; Lucki, I; Mangano, R; Martin, PT; Troy, SM; Unruh, MA	1
Daily, JP; Durol, AL; Graf, JA; Greenblatt, DJ; Harmatz, JS; Hoffman, JL; Mertzanis, P; Shader, RI; von Moltke, LL	1
Lelas, S; Rowlett, JK; Spealman, RD	1
Akaho, R; Ichikawa, I; Kanno, O; Nakagome, K; Nakajima, T; Sasaki, T; Suzuki, M; Takazawa, S; Watanabe, H	1
Bickel, WK; Smith, BJ	1
Cook, JM; Ma, C; Miczek, KA; Rowlett, JK; Tornatzky, W	1
Backhaus, J; Berger, M; Feige, B; Hohagen, F; Hornyak, M; Riemann, D; Voderholzer, U	1
Biggio, G; Busonero, F; Carta, M; Maciocco, E; Massa, F; Peis, M; Sanna, E; Talani, G	1
Cook, J; Ma, C; Platt, DM; Rowlett, JK; Spealman, RD	1
Rush, CR; Stoops, WW	1
Kulkarni, SK; Kumar, A	1
Foster, AC; Grigoriadis, DE; Gross, RS; Petroski, RE; Sullivan, SK; Verge, G	1
Chen, HY; Kuo, TB; Lai, CJ; Shaw, FZ; Yang, CC	1
Ishii, M; Ito, H; Nakamura, M; Niwa, Y; Yamazaki, M	1
Boric, K; Cárdenas, AM; Galli, I; Henríquez-Roldán, CF; Meléndez, J; Ortega, A; Zuñiga, L	1
Cabodi, S; Cotroneo, A; De Sarro, G; Gareri, P; Grassone, D; Lacava, R; Maina, E; Nicoletti, N	1
Aton, SJ; Coleman, T; Dumoulin, MC; Frank, MG; Jha, SK; Seibt, J	1
Echizenya, M; Iwaki, S; Shimizu, T; Suda, H	1
Kehne, JH; Malison, RT; Morgan, PT; Sprenger, KJ	1
Marin, SJ; McMillin, GA; Roberts, M; Wood, M	1
Greenblatt, DJ; Zammit, GK	1
Cook, JM; Makaron, L; Moran, CA; Namjoshi, O; Rallapalli, S; Rowlett, JK	1
Ator, NA; Biawat, P; Clayton, T; Cook, JM; Rallapalli, SK; Soto, PL; Weed, MR	1
Darnell, SB; Huizenga, MN; Licata, SC; Rowlett, JK; Rudolph, U; Sadri-Vakili, G; Sangrey, GR; Shinday, NM	1
In, MK; Jeong, YD; Kim, JY; Kim, MK; Paeng, KJ; Suh, SI	1
Ito, W; Kanbayashi, T; Nishino, S; Satake, M; Shimizu, K; Shimizu, T; Shioya, T; Uemura, SI; Wakasa, M	1
Fukase, Y; Hakamata, Y; Kumagai, Y; Kuroyama, M; Matsunaga, Y; Murayama, N; Tagaya, H	1
Puustinen, J	1
Min, JY; Min, KB	1
Ishikawa, A; Kakehashi, H; Kamata, T; Katagi, M; Nakano-Fujii, S; Nitta, A; Sasaki, K; Sato, T; Shima, N; Wada, M	1

Reviews

3 review(s) available for zolpidem and triazolam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Comparative clinical profiles of triazolam versus other shorter-acting hypnotics. The Journal of clinical psychiatry, 1992, Volume: 53 Suppl Topics: Azabicyclo Compounds; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Receptors, GABA-A; Sleep Initiation and Maintenance Disorders; Triazolam; Zolpidem	1992
Zolpidem: distinct from triazolam? The Annals of pharmacotherapy, 1997, Volume: 31, Issue:5 Topics: Humans; Hypnotics and Sedatives; Pyridines; Sleep Initiation and Maintenance Disorders; Triazolam; Zolpidem	1997

Trials

30 trial(s) available for zolpidem and triazolam

Article	Year
Comparison of the daytime sleep and performance effects of zolpidem versus triazolam. Psychopharmacology, 1992, Volume: 107, Issue:1 Topics: Adolescent; Adult; Humans; Hypnotics and Sedatives; Male; Psychomotor Performance; Pyridines; Sleep; Triazolam; Wakefulness; Zolpidem	1992
Abuse liability assessment of anxiolytics/hypnotics: rationale and laboratory lore. British journal of addiction, 1991, Volume: 86, Issue:12 Topics: Anti-Anxiety Agents; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Pyridines; Risk Factors; Substance-Related Disorders; Triazolam; Zolpidem	1991
Zolpidem and triazolam in humans: behavioral and subjective effects and abuse liability. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3 Topics: Adult; Behavior; Cognition; Dose-Response Relationship, Drug; Humans; Male; Psychomotor Performance; Pyridines; Substance-Related Disorders; Time Factors; Triazolam; Zolpidem	1990
Zolpidem and triazolam in humans: behavioral effects and abuse liability. NIDA research monograph, 1989, Volume: 95 Topics: Arousal; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypnotics and Sedatives; Mental Recall; Psychomotor Performance; Pyridines; Randomized Controlled Trials as Topic; Substance-Related Disorders; Triazolam; Zolpidem	1989
Effects of daytime administration of zolpidem versus triazolam on memory. European journal of clinical pharmacology, 1995, Volume: 48, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Double-Blind Method; Humans; Hypnotics and Sedatives; Memory; Mental Recall; Polysomnography; Pyridines; Sleep; Time Factors; Triazolam; Zolpidem	1995
Sedative, memory, and performance effects of hypnotics. Psychopharmacology, 1994, Volume: 116, Issue:2 Topics: Adult; Arousal; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Electrooculography; Female; Humans; Hypnotics and Sedatives; Male; Memory; Polysomnography; Psychomotor Performance; Pyridines; Reaction Time; Triazolam; Zolpidem	1994
Zolpidem and rebound insomnia--a double-blind, controlled polysomnographic study in chronic insomniac patients. Pharmacopsychiatry, 1994, Volume: 27, Issue:4 Topics: Adult; Aged; Anxiety; Chronic Disease; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Polysomnography; Psychiatric Status Rating Scales; Pyridines; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Triazolam; Zolpidem	1994
Randomized, double blind trial of zolpidem 10 mg versus triazolam 0.25 mg for treatment of insomnia in general practice. Scandinavian journal of primary health care, 1994, Volume: 12, Issue:2 Topics: Adult; Aged; Circadian Rhythm; Double-Blind Method; Family Practice; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pyridines; Sleep; Sleep Initiation and Maintenance Disorders; Triazolam; Zolpidem	1994
Comparison of the effects of zolpidem and triazolam on memory functions, psychomotor performances, and postural sway in healthy subjects. Journal of clinical psychopharmacology, 1993, Volume: 13, Issue:2 Topics: Adult; Double-Blind Method; Flicker Fusion; Humans; Hypnotics and Sedatives; Male; Mental Recall; Paired-Associate Learning; Pattern Recognition, Visual; Postural Balance; Posture; Psychomotor Performance; Pyridines; Reaction Time; Sensory Thresholds; Triazolam; Zolpidem	1993
Acute effects of zolpidem, triazolam and flunitrazepam on arterial blood gases and control of breathing in severe COPD. The European respiratory journal, 1993, Volume: 6, Issue:5 Topics: Blood Gas Analysis; Carbon Dioxide; Flunitrazepam; Humans; Hypnotics and Sedatives; Lung Diseases, Obstructive; Middle Aged; Oxygen; Pyridines; Respiration; Triazolam; Zolpidem	1993
Reversal of triazolam- and zolpidem-induced memory impairment by flumazenil. Psychopharmacology, 1995, Volume: 121, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Flumazenil; Humans; Hypnotics and Sedatives; Male; Memory; Placebo Effect; Pyridines; Time Factors; Triazolam; Volunteers; Zolpidem	1995
Zolpidem, triazolam, and temazepam: behavioral and subject-rated effects in normal volunteers. Journal of clinical psychopharmacology, 1996, Volume: 16, Issue:2 Topics: Adult; Anti-Anxiety Agents; Arousal; Attention; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Mental Recall; Middle Aged; Neuropsychological Tests; Psychomotor Performance; Pyridines; Serial Learning; Temazepam; Triazolam; Zolpidem	1996
Effects of daytime administration of zolpidem and triazolam on performance. Aviation, space, and environmental medicine, 1996, Volume: 67, Issue:2 Topics: Adult; Cognition; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Hypnotics and Sedatives; Male; Pyridines; Triazolam; Zolpidem	1996
Discriminative stimulus effects of zolpidem in pentobarbital-trained subjects: II. Comparison with triazolam and caffeine in humans. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:1 Topics: Adult; Caffeine; Discrimination Learning; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pentobarbital; Pyridines; Triazolam; Zolpidem	1997
Evaluation of zolpidem, triazolam, and placebo as hypnotic drugs the night before surgery. Journal of clinical anesthesia, 1997, Volume: 9, Issue:2 Topics: Adult; Aged; Analysis of Variance; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Preanesthetic Medication; Pyridines; Sleep; Triazolam; Zolpidem	1997
Minimal rebound insomnia after treatment with 10-mg zolpidem. Clinical neuropharmacology, 1997, Volume: 20, Issue:2 Topics: Adult; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Polysomnography; Pyridines; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Triazolam; Zolpidem	1997
Multidrug comparison (lorazepam, triazolam, zolpidem, and zopiclone) in situational insomnia: polysomnographic analysis by means of the cyclic alternating pattern. Clinical neuropharmacology, 1997, Volume: 20, Issue:3 Topics: Adult; Azabicyclo Compounds; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Piperazines; Polysomnography; Pyridines; Sex Factors; Sleep Initiation and Maintenance Disorders; Triazolam; Zolpidem	1997
Benzodiazepine-receptor ligands in humans: acute performance-impairing, subject-rated and observer-rated effects. Journal of clinical psychopharmacology, 1998, Volume: 18, Issue:2 Topics: Acute Disease; Adult; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; GABA Modulators; Humans; Hypnotics and Sedatives; Learning; Ligands; Male; Mental Recall; Middle Aged; Psychomotor Performance; Pyridines; Receptors, GABA-A; Sleep Stages; Surveys and Questionnaires; Triazolam; Zolpidem	1998
Triazolam and zolpidem: a comparison of their psychomotor, cognitive, and subjective effects in healthy volunteers. Behavioural pharmacology, 1997, Volume: 8, Issue:6-7 Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Mental Recall; Psychomotor Performance; Pyridines; Time Perception; Triazolam; Zolpidem	1997
Triazolam and zolpidem: effects on human memory and attentional processes. Psychopharmacology, 1999, Volume: 144, Issue:1 Topics: Adult; Analysis of Variance; Attention; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypnotics and Sedatives; Male; Memory; Middle Aged; Psychomotor Performance; Pyridines; Time Factors; Triazolam; Zolpidem	1999
Independent sleep EEG slow-wave and spindle band dynamics associated with 4 weeks of continuous application of short-half-life hypnotics in healthy subjects. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 1999, Volume: 110, Issue:11 Topics: Adult; Azabicyclo Compounds; Double-Blind Method; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Piperazines; Polysomnography; Pyridines; Sleep; Substance Withdrawal Syndrome; Triazolam; Zolpidem	1999
Discriminative-stimulus effects of zolpidem, triazolam, pentobarbital, and caffeine in zolpidem-trained humans. Experimental and clinical psychopharmacology, 2000, Volume: 8, Issue:1 Topics: Adult; Caffeine; Central Nervous System Stimulants; Cues; Discrimination Learning; Discrimination, Psychological; Female; Humans; Hypnotics and Sedatives; Male; Mental Recall; Pentobarbital; Psychomotor Performance; Pyridines; Surveys and Questionnaires; Triazolam; Zolpidem	2000
Comparative kinetics and response to the benzodiazepine agonists triazolam and zolpidem: evaluation of sex-dependent differences. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:2 Topics: Adult; Affect; Area Under Curve; Chromatography, Gas; Cross-Over Studies; Double-Blind Method; Electroencephalography; Female; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; Half-Life; Humans; Hypnotics and Sedatives; Male; Middle Aged; Psychomotor Performance; Pyridines; Sex Characteristics; Triazolam; Zolpidem	2000
Comparison of the effects of zaleplon, zolpidem, and triazolam on memory, learning, and psychomotor performance. Journal of clinical psychopharmacology, 2000, Volume: 20, Issue:3 Topics: Acetamides; Adolescent; Adult; Affect; Association Learning; Attention; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Learning; Male; Memory; Mental Recall; Middle Aged; Psychomotor Performance; Pyridines; Pyrimidines; Sex Characteristics; Surveys and Questionnaires; Triazolam; Zolpidem	2000
Differential impairment of triazolam and zolpidem clearance by ritonavir. Journal of acquired immune deficiency syndromes (1999), 2000, Jun-01, Volume: 24, Issue:2 Topics: Adult; Anti-Anxiety Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Half-Life; HIV Protease Inhibitors; HIV Seronegativity; Humans; Hypnotics and Sedatives; Male; Metabolic Clearance Rate; Oxidoreductases, N-Demethylating; Pyridines; Ritonavir; Triazolam; Zolpidem	2000
Comparison of the effects of zolpidem and triazolam on nocturnal sleep and sleep latency in the morning: a cross-over study in healthy young volunteers. Progress in neuro-psychopharmacology & biological psychiatry, 2000, Volume: 24, Issue:6 Topics: Adult; Affect; Anti-Anxiety Agents; Cross-Over Studies; Humans; Hypnotics and Sedatives; Male; Pyridines; Sleep; Sleep Wake Disorders; Triazolam; Zolpidem	2000
A double-blind, randomized and placebo-controlled study on the polysomnographic withdrawal effects of zopiclone, zolpidem and triazolam in healthy subjects. European archives of psychiatry and clinical neuroscience, 2001, Volume: 251, Issue:3 Topics: Adult; Azabicyclo Compounds; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Piperazines; Polysomnography; Pyridines; Reference Values; Sleep; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Triazolam; Zolpidem	2001
Temporal changes in postural sway caused by ultrashort-acting hypnotics: triazolam and zolpidem. ORL; journal for oto-rhino-laryngology and its related specialties, 2005, Volume: 67, Issue:2 Topics: Accidental Falls; Adult; Double-Blind Method; Gait; Humans; Hypnotics and Sedatives; Male; Posture; Pyridines; Time Factors; Triazolam; Zolpidem	2005
Zolpidem and triazolam do not affect the nocturnal sleep-induced memory improvement. Psychopharmacology, 2005, Volume: 181, Issue:1 Topics: Administration, Oral; Adult; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Male; Mental Recall; Neuropsychological Tests; Pyridines; Sleep; Statistics as Topic; Triazolam; Vocabulary; Zolpidem	2005
Residual effects of zolpidem, triazolam, rilmazafone and placebo in healthy elderly subjects: a randomized double-blind study. Sleep medicine, 2015, Volume: 16, Issue:11 Topics: Aged; Cross-Over Studies; Double-Blind Method; Female; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Middle Aged; Psychomotor Performance; Pyridines; Triazolam; Triazoles; Zolpidem	2015

Other Studies

48 other study(ies) available for zolpidem and triazolam

Article	Year
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach. Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1 Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
Zolpidem behavioral pharmacology in baboons: self-injection, discrimination, tolerance and withdrawal. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3 Topics: Animals; Barbiturates; Cocaine; Discrimination Learning; Drug Tolerance; Hypnotics and Sedatives; Male; Papio; Pyridines; Receptors, GABA-A; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Substance-Related Disorders; Triazolam; Zolpidem	1992
Comparative in vivo and in vitro regional selectivity of central omega (benzodiazepine) site ligands in inhibiting [3H]flumazenil binding in the rat central nervous system. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: Animals; Benzodiazepines; Binding Sites; Binding, Competitive; Brain Chemistry; Cell Membrane; Central Nervous System; Flumazenil; Hypnotics and Sedatives; Pyridazines; Pyridines; Rats; Receptors, GABA-A; Triazolam; Zolpidem	1992
Differential development of tolerance to the depressant effects of benzodiazepine and non-benzodiazepine agonists at the omega (BZ) modulatory sites of GABAA receptors. Neuropharmacology, 1992, Volume: 31, Issue:7 Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Binding Sites; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Tolerance; Male; Midazolam; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, GABA-A; Reinforcement, Psychology; Triazolam; Zolpidem	1992
The hypnotics triazolam and zolpidem have identical metabolic effects throughout the brain: implications for benzodiazepine receptor subtypes. Brain research, 1991, Jul-19, Volume: 554, Issue:1-2 Topics: Animals; Brain; Dose-Response Relationship, Drug; Energy Metabolism; Hypnotics and Sedatives; Male; Organ Specificity; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord; Triazolam; Zolpidem	1991
Comparison of zolpidem (Z), triazolam (T), and flunitrazepam (F) effects on arterial blood gases and control of breathing in patients with severe chronic obstructive pulmonary disease (COPD). Chest, 1990, Volume: 97, Issue:3 Suppl Topics: Flunitrazepam; Humans; Hypnotics and Sedatives; Lung Diseases, Obstructive; Pyridines; Respiratory Center; Triazolam; Zolpidem	1990
Effects of zolpidem, a new imidazopyridine hypnotic, on the acquisition of conditioned fear in mice. Comparison with triazolam and CL 218,872. Psychopharmacology, 1986, Volume: 90, Issue:2 Topics: Animals; Anti-Anxiety Agents; Conditioning, Operant; Fear; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pyridazines; Pyridines; Triazolam; Zolpidem	1986
Effects of chronic treatment with triazolam on operant responding in rats. Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:3 Topics: Animals; Conditioning, Operant; Drug Tolerance; Flumazenil; Hypnotics and Sedatives; Male; Pyridines; Rats; Rats, Wistar; Reinforcement Schedule; Time Factors; Triazolam; Zolpidem	1994
[Acute overdose of Zolpidem (Stilnox)]. Schweizerische medizinische Wochenschrift, 1996, May-04, Volume: 126, Issue:18 Topics: Adolescent; Adult; Aged; Antidotes; Coma; Drug Overdose; Female; Flumazenil; Humans; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Pyridines; Retrospective Studies; Triazolam; Zolpidem	1996
Expression and pharmacology of human GABAA receptors containing gamma 3 subunits. European journal of pharmacology, 1995, Nov-30, Volume: 291, Issue:3 Topics: Amino Acid Sequence; Animals; Anti-Anxiety Agents; Base Sequence; Benzodiazepines; Benzodiazepinones; Carbolines; Flumazenil; Flunitrazepam; GABA Modulators; Humans; Molecular Sequence Data; Pyrazoles; Pyridazines; Pyridines; Receptors, GABA-A; Recombinant Proteins; Sequence Homology, Amino Acid; Triazolam; Xenopus; Zolpidem	1995
Discriminative stimulus effects of zolpidem in pentobarbital-trained subjects: I. Comparison with triazolam in rhesus monkeys and rats. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:1 Topics: Animals; Discrimination Learning; Dose-Response Relationship, Drug; Female; Hypnotics and Sedatives; Macaca mulatta; Male; Pentobarbital; Pyridines; Rats; Rats, Sprague-Dawley; Species Specificity; Triazolam; Zolpidem	1997
Insomnia. The New England journal of medicine, 1997, Jun-26, Volume: 336, Issue:26 Topics: Humans; Hypnotics and Sedatives; Pyridines; Sleep Initiation and Maintenance Disorders; Triazolam; Zolpidem	1997
Comment: zolpidem: distinct from triazolam? The Annals of pharmacotherapy, 1997, Volume: 31, Issue:11 Topics: Humans; Hypnotics and Sedatives; Pyridines; Sleep Initiation and Maintenance Disorders; Triazolam; Zolpidem	1997
Zolpidem is differentiated from triazolam in humans using a three-response drug discrimination procedure. Behavioural pharmacology, 1998, Volume: 9, Issue:7 Topics: Adult; Cognition; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Male; Psychomotor Performance; Pyridines; Surveys and Questionnaires; Time Factors; Triazolam; Zolpidem	1998
Limited anxiolytic-like effects of non-benzodiazepine hypnotics in rodents. Journal of psychopharmacology (Oxford, England), 1998, Volume: 12, Issue:4 Topics: Acetamides; Animals; Anti-Anxiety Agents; Avoidance Learning; Azabicyclo Compounds; Benzodiazepines; Escape Reaction; Hypnotics and Sedatives; Male; Maze Learning; Motor Activity; Piperazines; Punishment; Pyridines; Pyrimidines; Rats; Rats, Wistar; Triazolam; Zolpidem	1998
The effects of benzodiazepine (triazolam), cyclopyrrolone (zopiclone) and imidazopyridine (zolpidem) hypnotics on the frequency of hippocampal theta activity and sleep structure in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2 Topics: Animals; Azabicyclo Compounds; Hypnotics and Sedatives; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Sleep; Sleep, REM; Theta Rhythm; Triazolam; Wakefulness; Zolpidem	1999
Different effects of L-type and T-type calcium channel blockers on the hypnotic potency of triazolam and zolpidem in rats. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:4 Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Drug Interactions; Flunarizine; Hypnotics and Sedatives; Male; Nifedipine; Pyridines; Rats; Rats, Wistar; Sleep, REM; Triazolam; Zolpidem	1999
Acute behavioral effects and abuse potential of trazodone, zolpidem and triazolam in humans. Psychopharmacology, 1999, Volume: 144, Issue:3 Topics: Adult; Antidepressive Agents, Tricyclic; Humans; Hypnotics and Sedatives; Male; Memory; Mental Recall; Postural Balance; Psychomotor Performance; Pyridines; Substance-Related Disorders; Surveys and Questionnaires; Time Factors; Trazodone; Triazolam; Zolpidem	1999
Response-rate suppression in operant paradigm as predictor of soporific potency in rats and identification of three novel sedative-hypnotic neuroactive steroids. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3 Topics: Animals; Conditioning, Operant; Depression, Chemical; Dose-Response Relationship, Drug; Electroencephalography; Hypnotics and Sedatives; Male; Pentobarbital; Postural Balance; Pregnanolone; Pregnenolone; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Steroids; Triazolam; Zolpidem	1999
Transduction of the discriminative stimulus effects of zolpidem by GABA(A)/alpha1 receptors. European journal of pharmacology, 2000, Oct-06, Volume: 406, Issue:1 Topics: Acetamides; Animals; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; GABA Agonists; GABA Modulators; GABA-A Receptor Agonists; Male; Protein Subunits; Pyridines; Pyrimidines; Reinforcement Schedule; Saimiri; Triazolam; Zolpidem	2000
Effects of alprazolam, caffeine, and zolpidem in humans trained to discriminate triazolam from placebo. Drug and alcohol dependence, 2001, Feb-01, Volume: 61, Issue:3 Topics: Adolescent; Adult; Alprazolam; Analysis of Variance; Caffeine; Discrimination, Psychological; Female; GABA Agonists; GABA Modulators; Humans; Male; Phosphodiesterase Inhibitors; Pyridines; Triazolam; Zolpidem	2001
Zolpidem, triazolam, and diazepam decrease distress vocalizations in mouse pups: differential antagonism by flumazenil and beta-Carboline-3-carboxylate-t-butyl ester (beta-CCt). The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1 Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Body Temperature; Carbolines; Diazepam; Dose-Response Relationship, Drug; Flumazenil; GABA-A Receptor Antagonists; Mice; Pyridines; Receptors, GABA-A; Triazolam; Vocalization, Animal; Zolpidem	2001
Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes. European journal of pharmacology, 2002, Sep-13, Volume: 451, Issue:2 Topics: Acetamides; Animals; Cerebral Cortex; Female; Humans; Male; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Triazolam; Xenopus laevis; Zolpidem	2002
Selective antagonism of the ataxic effects of zolpidem and triazolam by the GABAA/alpha1-preferring antagonist beta-CCt in squirrel monkeys. Psychopharmacology, 2002, Volume: 164, Issue:2 Topics: Animals; Ataxia; Benzodiazepines; Carbolines; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; GABA Agonists; GABA Modulators; GABA-A Receptor Antagonists; Male; Motor Activity; Pyridines; Receptors, GABA-A; Saimiri; Social Behavior; Triazolam; Zolpidem	2002
Differential effects in humans after repeated administrations of zolpidem and triazolam. The American journal of drug and alcohol abuse, 2003, Volume: 29, Issue:2 Topics: Adult; Female; GABA Agonists; GABA Modulators; Humans; Male; Memory; Mental Recall; Psychomotor Performance; Pyridines; Surveys and Questionnaires; Time Factors; Triazolam; Zolpidem	2003
On the sleep promoting effects of BR-16A: interaction with GABAergic modulators. Indian journal of experimental biology, 2004, Volume: 42, Issue:5 Topics: Alprazolam; Animals; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Modulators; Hypnosis; Hypnotics and Sedatives; Male; Medicine, Ayurvedic; Melatonin; Mice; Plant Extracts; Pyridines; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors; Triazolam; Zolpidem	2004
Characterization of the interaction of indiplon, a novel pyrazolopyrimidine sedative-hypnotic, with the GABAA receptor. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:2 Topics: Acetamides; Animals; Azides; Benzodiazepines; Binding Sites; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Chloride Channels; Flumazenil; GABA Modulators; gamma-Aminobutyric Acid; Kinetics; Male; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Thiophenes; Triazolam; Tritium; Zolpidem	2004
Sleep-related vagotonic effect of zolpidem in rats. Psychopharmacology, 2005, Volume: 181, Issue:2 Topics: Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electrocardiography; Electroencephalography; Electromyography; Heart Rate; Hypnotics and Sedatives; Male; Pyridines; Rats; Rats, Inbred WKY; Sleep; Sleep, REM; Spectrum Analysis; Time Factors; Triazolam; Vagus Nerve; Zolpidem	2005
Effectiveness and safety of hypnotic drugs in the treatment of insomnia in over 70-year old people. Archives of gerontology and geriatrics, 2007, Volume: 44 Suppl 1 Topics: Aged; Cognition Disorders; Dementia; Depression; Drug Administration Schedule; Female; Health Status; Humans; Hypnotics and Sedatives; Male; Neuropsychological Tests; Oxazepam; Primary Health Care; Psychomotor Agitation; Pyridines; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Triazolam; Zolpidem	2007
The non-benzodiazepine hypnotic zolpidem impairs sleep-dependent cortical plasticity. Sleep, 2008, Volume: 31, Issue:10 Topics: Animals; Brain Mapping; Cats; Cerebral Cortex; Dominance, Cerebral; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials, Visual; Female; Hypnotics and Sedatives; Indenes; Injections, Intraperitoneal; Male; Neuronal Plasticity; Polysomnography; Pyridines; Signal Processing, Computer-Assisted; Sleep; Sleep Stages; Tomography, Optical Coherence; Triazolam; Zolpidem	2008
Paradoxical reactions to hypnotic agents in adolescents with free-running disorder. Psychiatry and clinical neurosciences, 2009, Volume: 63, Issue:3 Topics: Adolescent; Anti-Anxiety Agents; Azepines; Dyskinesia, Drug-Induced; Female; Humans; Hypnotics and Sedatives; Male; Pyridines; Sleep Disorders, Circadian Rhythm; Triazolam; Zolpidem	2009
Retrograde effects of triazolam and zolpidem on sleep-dependent motor learning in humans. Journal of sleep research, 2010, Volume: 19, Issue:1 Pt 2 Topics: Adult; Arousal; Cognition Disorders; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Humans; Hypnotics and Sedatives; Learning; Male; Memory; Middle Aged; Movement; Polysomnography; Pyridines; Reaction Time; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazolam; Zolpidem	2010
Sensitive UPLC-MS-MS assay for 21 benzodiazepine drugs and metabolites, zolpidem and zopiclone in serum or plasma. Journal of analytical toxicology, 2012, Volume: 36, Issue:7 Topics: Azabicyclo Compounds; Benzodiazepines; Chromatography, Liquid; Humans; Liquid-Liquid Extraction; Lorazepam; Mass Spectrometry; Nordazepam; Oxazepam; Piperazines; Plasma; Pyridines; Serum; Specimen Handling; Tandem Mass Spectrometry; Temazepam; Triazolam; Zolpidem	2012
Pharmacokinetic evaluation of eszopiclone: clinical and therapeutic implications. Expert opinion on drug metabolism & toxicology, 2012, Volume: 8, Issue:12 Topics: Acetamides; Adult; Aged; Azabicyclo Compounds; Clinical Trials as Topic; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Eszopiclone; Half-Life; Hepatic Insufficiency; Humans; Hypnotics and Sedatives; Piperazines; Pyridines; Pyrimidines; Receptors, GABA-A; Sleep; Sleep Initiation and Maintenance Disorders; Triazolam; United States; Zolpidem	2012
Cognition-impairing effects of benzodiazepine-type drugs: role of GABAA receptor subtypes in an executive function task in rhesus monkeys. Pharmacology, biochemistry, and behavior, 2013, Volume: 104 Topics: Acetamides; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbolines; Cognition; Executive Function; Female; GABA-A Receptor Antagonists; Hypnotics and Sedatives; Imidazoles; Macaca mulatta; Pyridines; Pyrimidines; Receptors, GABA-A; Triazolam; Zolpidem	2013
Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected]. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013, Volume: 38, Issue:11 Topics: Acetamides; Allosteric Regulation; Animals; Benzodiazepines; Conditioning, Operant; Diazepam; Dose-Response Relationship, Drug; Imidazoles; Macaca mulatta; Male; Memory, Short-Term; Pyridazines; Pyridines; Pyrimidines; Receptors, GABA-A; Recognition, Psychology; Triazolam; Triazoles; Zolpidem	2013
Alterations in brain-derived neurotrophic factor in the mouse hippocampus following acute but not repeated benzodiazepine treatment. PloS one, 2013, Volume: 8, Issue:12 Topics: Analysis of Variance; Animals; Benzodiazepines; Blotting, Western; Brain-Derived Neurotrophic Factor; Chromatin Immunoprecipitation; Cyclic AMP Response Element-Binding Protein; Diazepam; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Genes, Immediate-Early; Hippocampus; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Triazolam; Zolpidem	2013
Rapid determination of benzodiazepines, zolpidem and their metabolites in urine using direct injection liquid chromatography-tandem mass spectrometry. Forensic science international, 2015, Volume: 257 Topics: Alprazolam; Benzodiazepines; Chromatography, Liquid; Flurazepam; Forensic Toxicology; Humans; Hypnotics and Sedatives; Limit of Detection; Pyridines; Tandem Mass Spectrometry; Triazolam; Zolpidem	2015
Effects of zolpidem/triazolam on cognitive performance 12 hours after acute administration. Sleep medicine, 2018, Volume: 52 Topics: Adult; Anti-Anxiety Agents; Cognition; Humans; Male; Neuropsychological Tests; Polysomnography; Sleep Aids, Pharmaceutical; Triazolam; Young Adult; Zolpidem	2018
Benzodiazepines and Z-drugs may cause prolonged cognitive issues in young adults - are hypnotics not only a geriatric dilemma? Sleep medicine, 2018, Volume: 52 Topics: Aged; Benzodiazepines; Cognition; Humans; Hypnotics and Sedatives; Pharmaceutical Preparations; Triazolam; Young Adult; Zolpidem	2018
Outdoor Artificial Nighttime Light and Use of Hypnotic Medications in Older Adults: A Population-Based Cohort Study. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2018, 11-15, Volume: 14, Issue:11 Topics: Age Factors; Aged; Cohort Studies; Drug Utilization Review; Female; Humans; Hypnotics and Sedatives; Lighting; Male; Middle Aged; Republic of Korea; Risk Factors; Sleep Initiation and Maintenance Disorders; Triazolam; Zolpidem	2018
Incorporation of five common hypnotics into hair after a single dose and application to a forensic case of drug facilitated crimes. Forensic science international, 2021, Volume: 325 Topics: Adult; Asian People; Chromatography, Liquid; Crime; Diazepam; Female; Flunitrazepam; Forensic Toxicology; Hair; Humans; Hypnotics and Sedatives; Male; Mass Spectrometry; Nitrazepam; Substance Abuse Detection; Triazolam; Zolpidem	2021