Page last updated: 2024-08-16

zolpidem and clarithromycin

zolpidem has been researched along with clarithromycin in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (6.67)	18.2507
2000's	4 (26.67)	29.6817
2010's	9 (60.00)	24.3611
2020's	1 (6.67)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Choi, Y; Raymer, BK	1
Gage, TW	1
Court, MH; Farkas, D; Greenblatt, DJ; Harmatz, JS; Volak, LP; von Moltke, LL	1
Byeon, JY; Chae, WK; Jang, CG; Jung, EH; Kim, SH; Kim, YH; Lee, CM; Lee, SY; Lee, YJ	1
Byeon, JY; Jang, CG; Jung, EH; Kim, SH; Lee, CM; Lee, SY; Lee, YJ	1
Byeon, JY; Cho, CK; Jang, CG; Jung, EH; Lee, CM; Lee, SY; Lee, YJ; Lim, CW; Oh, KY; Shin, HB	1

Reviews

2 review(s) available for zolpidem and clarithromycin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Sleep modulating agents. Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16 Topics: Animals; Humans; Sleep; Sleep Aids, Pharmaceutical; Sleep Wake Disorders; Wakefulness-Promoting Agents	2019

Trials

1 trial(s) available for zolpidem and clarithromycin

Article	Year
Short-term clarithromycin administration impairs clearance and enhances pharmacodynamic effects of trazodone but not of zolpidem. Clinical pharmacology and therapeutics, 2009, Volume: 85, Issue:6 Topics: Adult; Anti-Anxiety Agents; Anti-Bacterial Agents; Area Under Curve; Clarithromycin; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pyridines; Trazodone; Zolpidem	2009

Article

Year

Short-term clarithromycin administration impairs clearance and enhances pharmacodynamic effects of trazodone but not of zolpidem.

Clinical pharmacology and therapeutics, 2009, Volume: 85, Issue:6

Topics: Adult; Anti-Anxiety Agents; Anti-Bacterial Agents; Area Under Curve; Clarithromycin; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pyridines; Trazodone; Zolpidem

2009

Other Studies

12 other study(ies) available for zolpidem and clarithromycin

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
New drugs from 1991-1992. Texas dental journal, 1993, Volume: 110, Issue:7 Topics: 1-Naphthylamine; Anti-Bacterial Agents; Anti-Infective Agents; Anticholesteremic Agents; Antineoplastic Agents; Antiviral Agents; Azithromycin; Butanones; Cardiovascular Agents; Clarithromycin; Drug Approval; Drug Combinations; Drug Interactions; Enoxacin; Finasteride; Flumazenil; Fluoroquinolones; Humans; Ketorolac Tromethamine; Lactams; Nabumetone; Pyridines; Quinolones; Sertraline; Tolmetin; Tromethamine; United States; United States Food and Drug Administration; Zolpidem	1993
Effects of genetic polymorphisms of CYP2C19 on the pharmacokinetics of zolpidem. Archives of pharmacal research, 2018, Volume: 41, Issue:8 Topics: Administration, Oral; Adult; Clarithromycin; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Dose-Response Relationship, Drug; Genotype; Healthy Volunteers; Humans; Male; Polymorphism, Genetic; Pyridines; Young Adult; Zolpidem	2018
Effects of steady-state clarithromycin on the pharmacokinetics of zolpidem in healthy subjects. Archives of pharmacal research, 2019, Volume: 42, Issue:12 Topics: Administration, Oral; Adult; Clarithromycin; Drug Combinations; Healthy Volunteers; Humans; Male; Republic of Korea; Young Adult; Zolpidem	2019
Relationship between plasma exposure of zolpidem and CYP2D6 genotype in healthy Korean subjects. Archives of pharmacal research, 2020, Volume: 43, Issue:9 Topics: Administration, Oral; Adult; Biological Variation, Population; Clarithromycin; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Healthy Volunteers; Humans; Hypnotics and Sedatives; Male; Pharmacogenomic Variants; Republic of Korea; Young Adult; Zolpidem	2020