Page last updated: 2024-08-16

zolpidem and caffeine

zolpidem has been researched along with caffeine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (8.70)18.2507
2000's12 (52.17)29.6817
2010's8 (34.78)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Goldman, NH; Madakasira, S; Rowlett, JK; Rush, CR; Woolverton, WL1
Mattila, MJ; Nurminen, ML; Vainio, P; Vanakoski, J1
Baker, RW; Rowlett, JK; Rush, CR1
Bickel, WK; Smith, BJ1
Batéjat, D; Beaumont, M; Coste, O; Lagarde, D; Piérard, C; Van Beers, P1
Hutson, PH; Ivarsson, M; Nutt, DJ; Paterson, LM; Wilson, SJ3
Cysneiros, RM; Farkas, D; Greenblatt, DJ; Harmatz, JS; von Moltke, LL1
Myslobodsky, M1
Fisher, SP; Foster, RG; Godinho, SI; Hankins, MW; Peirson, SN; Pothecary, CA1
Cho, S; Kim, D; Kim, SB; Kwon, S; Lee, J; Moon, KD; Yoon, M1
Anilanmert, B; Caglar-Andac, S; Narin, I1

Reviews

2 review(s) available for zolpidem and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The paradox of caffeine-zolpidem interaction: a network analysis.
    Current drug targets, 2009, Volume: 10, Issue:10

    Topics: Animals; Antioxidants; Caffeine; Central Nervous System Stimulants; Drug Synergism; Humans; Hypnotics and Sedatives; Melatonin; Pyridines; Reactive Oxygen Species; Software; Zolpidem

2009

Trials

7 trial(s) available for zolpidem and caffeine

ArticleYear
Discriminative stimulus effects of zolpidem in pentobarbital-trained subjects: II. Comparison with triazolam and caffeine in humans.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:1

    Topics: Adult; Caffeine; Discrimination Learning; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Pentobarbital; Pyridines; Triazolam; Zolpidem

1997
Zolpidem 10 mg given at daytime is not antagonized by 300 mg caffeine in man.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:5

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Circadian Rhythm; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Hypnotics and Sedatives; Male; Placebos; Pyridines; Zolpidem

1998
Discriminative-stimulus effects of zolpidem, triazolam, pentobarbital, and caffeine in zolpidem-trained humans.
    Experimental and clinical psychopharmacology, 2000, Volume: 8, Issue:1

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Cues; Discrimination Learning; Discrimination, Psychological; Female; Humans; Hypnotics and Sedatives; Male; Mental Recall; Pentobarbital; Psychomotor Performance; Pyridines; Surveys and Questionnaires; Triazolam; Zolpidem

2000
Prior sleep with zolpidem enhances the effect of caffeine or modafinil during 18 hours continuous work.
    Aviation, space, and environmental medicine, 2006, Volume: 77, Issue:5

    Topics: Adult; Aerospace Medicine; Attention; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Delayed-Action Preparations; Double-Blind Method; Electroencephalography; Fatigue; Humans; Hypnotics and Sedatives; Male; Memory; Military Medicine; Modafinil; Pyridines; Reaction Time; Sleep; Wakefulness; Work; Zolpidem

2006
A translational, caffeine-induced model of onset insomnia in rats and healthy volunteers.
    Psychopharmacology, 2007, Volume: 191, Issue:4

    Topics: Adult; Animals; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Disease Models, Animal; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Electromyography; GABA Agonists; Humans; Hypnotics and Sedatives; Male; Polysomnography; Pyridines; Rats; Rats, Sprague-Dawley; Reference Values; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Sleep; Sleep Initiation and Maintenance Disorders; Telemetry; Trazodone; Zolpidem

2007
Pharmacokinetic and pharmacodynamic interactions between zolpidem and caffeine.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:1

    Topics: Administration, Oral; Adult; Caffeine; Central Nervous System Stimulants; Cognition; Cross-Over Studies; Double-Blind Method; Drug Interactions; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Male; Mental Recall; Pyridines; Reaction Time; Sleep; Zolpidem

2007
Effects on sleep stages and microarchitecture of caffeine and its combination with zolpidem or trazodone in healthy volunteers.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:5

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Electroencephalography; Humans; Hypnotics and Sedatives; Male; Polysomnography; Pyridines; Sleep Initiation and Maintenance Disorders; Sleep Stages; Trazodone; Young Adult; Zolpidem

2009

Other Studies

14 other study(ies) available for zolpidem and caffeine

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Effects of alprazolam, caffeine, and zolpidem in humans trained to discriminate triazolam from placebo.
    Drug and alcohol dependence, 2001, Feb-01, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Alprazolam; Analysis of Variance; Caffeine; Discrimination, Psychological; Female; GABA Agonists; GABA Modulators; Humans; Male; Phosphodiesterase Inhibitors; Pyridines; Triazolam; Zolpidem

2001
Characterisation of the effects of caffeine on sleep in the rat: a potential model of sleep disruption.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:5

    Topics: Animals; Body Temperature; Caffeine; Central Nervous System Stimulants; Disease Models, Animal; Electroencephalography; Electromyography; Hypnotics and Sedatives; Male; Motor Activity; Pyridines; Rats; Rats, Sprague-Dawley; Sleep; Sleep Initiation and Maintenance Disorders; Telemetry; Trazodone; Zolpidem

2009
Rapid assessment of sleep-wake behavior in mice.
    Journal of biological rhythms, 2012, Volume: 27, Issue:1

    Topics: Animals; Automation, Laboratory; Behavior, Animal; Caffeine; Electroencephalography; Electromyography; Light; Male; Mice; Mice, Inbred C57BL; Monitoring, Physiologic; Pyridines; Sleep; Video Recording; Wakefulness; Zolpidem

2012
A Standardized Phlorotannin Supplement Attenuates Caffeine-Induced Sleep Disruption in Mice.
    Nutrients, 2019, Mar-06, Volume: 11, Issue:3

    Topics: Animals; Caffeine; Electroencephalography; Electromyography; Follow-Up Studies; Hypnotics and Sedatives; Mice; Phytotherapy; Plant Preparations; Polyphenols; Receptors, GABA-A; Seaweed; Sleep; Sleep Aids, Pharmaceutical; Sleep Initiation and Maintenance Disorders; Zolpidem

2019
Urgent first-step screening method for ketamine, phenobarbital, zopiclone, zolpidem, phenytoin and thiopental in adulterated soft drink.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:5

    Topics: Caffeine; Carbonated Beverages; Female; Humans; Ketamine; Phenobarbital; Phenytoin; Reproducibility of Results; Thiopental; Zolpidem

2023