Page last updated: 2024-08-16

zolpidem and alpidem

zolpidem has been researched along with alpidem in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.69)18.7374
1990's13 (50.00)18.2507
2000's2 (7.69)29.6817
2010's8 (30.77)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Biggio, G; Cagetti, E; Franco, M; Genchi, G; Latrofa, A; Liso, G; Ricciardi, L; Sanna, E; Trapani, G; Tuveri, F1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Soural, M; Vanda, D; Zajdel, P1
Cerra, B; Gioiello, A; Lozza, AM; Piccinno, A1
Dessibourg, CA1
Byrnes, JJ; Greenblatt, DJ; Miller, LG1
Bianchetti, G; Durand, A; Morselli, PL; Thénot, JP1
Advenier, C; Candenas, ML; Devillier, P; Naline, E1
De Luca, C; De Medici, D; Massotti, M1
Biggio, G; Carcangiu, G; Concas, A; Mereu, G; Passino, N1
Arbilla, S; Benavides, J; Langer, SZ; Scatton, B1
Arbilla, S; Langer, SZ2
Gaillard, Y; Gay-Montchamp, JP; Ollagnier, M1
Benavides, J; Peny, B; Ruano, D; Scatton, B; Vitorica, J1
Auta, J; Costa, E; Guidotti, A; Kozikowski, A; Ma, D; Romeo, E1
Bain, CJ; Kemp, JA; Wafford, KA; Whiting, PJ1
Kintz, P; Mangin, P; Tracqui, A1
Betti, L; Bistocchi, M; Giannaccini, G; Gori, M; Lucacchini, A1
Berson, A; Berthon, B; Descatoire, V; Fau, D; Feldmann, G; Maulny, B; Pessayre, D; Sutton, A; Tordjmann, T; Vadrot, N1
Chernyak, N; Gevorgyan, V1
Mobin, SM; Nair, DK; Namboothiri, IN1

Reviews

5 review(s) available for zolpidem and alpidem

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Imidazopyridine-based selective and multifunctional ligands of biological targets associated with psychiatric and neurodegenerative diseases.
    European journal of medicinal chemistry, 2019, Nov-01, Volume: 181

    Topics: Animals; Clinical Trials as Topic; Drug Design; Humans; Imidazoles; Ligands; Mental Disorders; Molecular Targeted Therapy; Neurodegenerative Diseases; Pyridines

2019
The Medicinal Chemistry in the Era of Machines and Automation: Recent Advances in Continuous Flow Technology.
    Journal of medicinal chemistry, 2020, 07-09, Volume: 63, Issue:13

    Topics: Automation; Chemistry, Pharmaceutical; Drug Discovery; Drug Evaluation, Preclinical; Humans

2020
Comparative pharmacokinetic profile of two imidazopyridine drugs: zolpidem and alpidem.
    Drug metabolism reviews, 1992, Volume: 24, Issue:2

    Topics: Animals; Imidazoles; Mice; Pyridines; Rats; Zolpidem

1992
Zolpidem and alpidem: two imidazopyridines with selectivity for omega 1- and omega 3-receptor subtypes.
    Advances in biochemical psychopharmacology, 1990, Volume: 46

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Chloride Channels; Chlorides; Hypnotics and Sedatives; Imidazoles; Membrane Proteins; Molecular Structure; Pyridines; Receptors, GABA-A; Zolpidem

1990

Other Studies

21 other study(ies) available for zolpidem and alpidem

ArticleYear
Synthesis and binding affinity of 2-phenylimidazo[1,2-alpha]pyridine derivatives for both central and peripheral benzodiazepine receptors. A new series of high-affinity and selective ligands for the peripheral type.
    Journal of medicinal chemistry, 1997, Sep-12, Volume: 40, Issue:19

    Topics: Animals; Benzodiazepinones; Binding, Competitive; Brain; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Imidazoles; Kidney; Kinetics; Male; Mitochondria; Molecular Structure; Oocytes; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Recombinant Proteins; Structure-Activity Relationship; Xenopus laevis; Zolpidem

1997
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
[Imidazopyridines, an alternative to benzodiazepines].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1992, Apr-21, Volume: 81, Issue:17

    Topics: Anti-Anxiety Agents; Humans; Hypnotics and Sedatives; Imidazoles; Pyridines; Zolpidem

1992
Benzodiazepine receptor binding of nonbenzodiazepines in vivo: alpidem, zolpidem and zopiclone.
    Brain research bulletin, 1992, Volume: 29, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Brain; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Hypnotics and Sedatives; Imidazoles; Male; Mice; Mice, Inbred Strains; Piperazines; Pyridines; Receptors, GABA-A; Reference Values; Zolpidem

1992
Influence of diazepam, alpidem, zolpidem and zopiclone, on the response to adenosine of the guinea pig isolated trachea.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Animals; Anti-Anxiety Agents; Diazepam; Dipyridamole; Dose-Response Relationship, Drug; Drug Interactions; Guinea Pigs; Histamine; Hypnotics and Sedatives; Imidazoles; Male; Muscle Contraction; Muscle, Smooth; Pyridines; Receptors, GABA-A; Trachea; Zolpidem

1991
Relative efficacies of benzodiazepine receptor agonists in affecting red nucleus electrical activity in rabbits.
    Psychopharmacology, 1990, Volume: 102, Issue:4

    Topics: Animals; Bicuculline; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Flumazenil; Flunitrazepam; Imidazoles; Isoquinolines; Male; Pentylenetetrazole; Pyridazines; Pyridines; Rabbits; Receptors, GABA-A; Red Nucleus; Zolpidem

1990
Reduction of reticulata neuronal activity by zolpidem and alpidem, two imidazopyridines with high affinity for type I benzodiazepine receptors.
    European journal of pharmacology, 1990, Apr-25, Volume: 179, Issue:3

    Topics: Action Potentials; Animals; Anti-Anxiety Agents; Diazepam; Flumazenil; Hypnotics and Sedatives; Imidazoles; Male; Neurons; Pyridines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reticular Formation; Zolpidem

1990
Limitations of the benzodiazepine receptor nomenclature: a proposal for a pharmacological classification as omega receptor subtypes.
    Fundamental & clinical pharmacology, 1988, Volume: 2, Issue:3

    Topics: Animals; Benzodiazepinones; Cerebellum; Diazepam; Imidazoles; Kidney; Pyridines; Rats; Receptors, GABA-A; Spinal Cord; Terminology as Topic; Zolpidem

1988
Imidazopyridines as a tool for the characterization of benzodiazepine receptors: a proposal for a pharmacological classification as omega receptor subtypes.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:4

    Topics: Animals; Brain Chemistry; Flunitrazepam; GABA-A Receptor Antagonists; Imidazoles; In Vitro Techniques; Isoquinolines; Kidney; Ligands; Pyridazines; Pyridines; Rats; Receptors, GABA-A; Spinal Cord; Terminology as Topic; Zolpidem

1988
Simultaneous screening and quantitation of alpidem, zolpidem, buspirone and benzodiazepines by dual-channel gas chromatography using electron-capture and nitrogen-phosphorus detection after solid-phase extraction.
    Journal of chromatography, 1993, Dec-22, Volume: 622, Issue:2

    Topics: Anti-Anxiety Agents; Benzodiazepines; Buspirone; Chromatography, Gas; Electrochemistry; Humans; Hypnotics and Sedatives; Imidazoles; Indicators and Reagents; Pyridines; Regression Analysis; Zolpidem

1993
Comparative autoradiographic distribution of central omega (benzodiazepine) modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem.
    Brain research, 1993, Feb-26, Volume: 604, Issue:1-2

    Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Autoradiography; Binding, Competitive; Brain; Flumazenil; Hypnotics and Sedatives; Imidazoles; Kinetics; Male; Organ Specificity; Pyridazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Spinal Cord; Tritium; Zolpidem

1993
Participation of mitochondrial diazepam binding inhibitor receptors in the anticonflict, antineophobic and anticonvulsant action of 2-aryl-3-indoleacetamide and imidazopyridine derivatives.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: Aggression; Allosteric Regulation; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Clonazepam; Desoxycorticosterone; Flumazenil; Imidazoles; Indoleacetic Acids; Isoniazid; Isoquinolines; Mitochondria; Phobic Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, GABA-A; Seizures; Zolpidem

1993
Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Base Sequence; Benzodiazepines; Binding Sites; DNA; Humans; Hypnotics and Sedatives; Imidazoles; Molecular Sequence Data; Oocytes; Pyridines; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis; Zolpidem

1993
High-performance liquid chromatographic assay with diode-array detection for toxicological screening of zopiclone, zolpidem, suriclone and alpidem in human plasma.
    Journal of chromatography, 1993, Jun-23, Volume: 616, Issue:1

    Topics: Adult; Anti-Anxiety Agents; Azabicyclo Compounds; Chromatography, High Pressure Liquid; Female; Humans; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Imidazoles; Naphthyridines; Piperazines; Pyridines; Spectrophotometry, Ultraviolet; Sulfur Compounds; Zolpidem

1993
[3H]Ro 15-1788 binding sites to brain membrane of the saltwater Mugil cephalus.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2001, Volume: 128, Issue:3

    Topics: Animals; Binding Sites; Binding, Competitive; Brain; Carbolines; Cell Membrane; Chlorides; Diazepam; Female; Fishes; Flumazenil; Flunitrazepam; gamma-Aminobutyric Acid; Imidazoles; Ionophores; Male; Pyridines; Receptors, GABA-A; Synaptosomes; Tritium; Zolpidem

2001
Toxicity of alpidem, a peripheral benzodiazepine receptor ligand, but not zolpidem, in rat hepatocytes: role of mitochondrial permeability transition and metabolic activation.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Diphosphate; Animals; Anti-Anxiety Agents; Biotransformation; Cells, Cultured; Cytochrome c Group; GABA-A Receptor Agonists; Hepatocytes; Imidazoles; Male; Membrane Potentials; Mitochondria, Liver; Oxidation-Reduction; Oxygen Consumption; Permeability; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zolpidem

2001
General and efficient copper-catalyzed three-component coupling reaction towards imidazoheterocycles: one-pot synthesis of alpidem and zolpidem.
    Angewandte Chemie (International ed. in English), 2010, Apr-01, Volume: 49, Issue:15

    Topics: Anti-Anxiety Agents; Catalysis; Copper; Cyclization; Heterocyclic Compounds; Imidazoles; Pyridines; Pyrimidines; Quinolines; Zolpidem

2010
Synthesis of imidazopyridines from the Morita-Baylis-Hillman acetates of nitroalkenes and convenient access to Alpidem and Zolpidem.
    Organic letters, 2012, Sep-07, Volume: 14, Issue:17

    Topics: Acetates; Alkenes; Catalysis; Combinatorial Chemistry Techniques; Imidazoles; Molecular Structure; Nitro Compounds; Pyridines; Stereoisomerism; Zolpidem

2012