zolpidem has been researched along with almorexant in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (90.91) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Beuckmann, CT; Kazuta, Y; Kushida, I; Nakagawa, M; Naoe, Y; Ozaki, F; Suzuki, M; Takenaka, O; Terauchi, T; Ueno, T; Yonaga, M; Yoshida, Y | 1 |
| Chiossi, E; de Haas, S; Dingemanse, J; Hoever, P; Schoemaker, RC; van Gerven, J; Winkler, J | 1 |
| Brisbare-Roch, C; Jenck, F; Lecourt, H; Steiner, MA; Strasser, DS | 1 |
| Cavallaro, M; Dingemanse, J; Hay, J; Hoever, P; Rad, M; van Gerven, JM | 1 |
| Chakraborty, B; Cruz, HG; Dingemanse, J; Hoever, P; Schoedel, K; Sellers, EM | 1 |
| Dittrich, L; Kilduff, TS; Morairty, SR; Warrier, DR | 1 |
| Gulati, S; Kilduff, TS; Mathew, TK; Neylan, TC; Nguyen, AT; Schwartz, MD; Vazquez-DeRose, J; Warrier, DR | 1 |
| Dittrich, L; Kilduff, TS; Morairty, SR; Neylan, TC; Palmerston, JB; Parks, GS; Schwartz, MD; Warrier, DR | 1 |
| Berkani, O; Black, J; Hajak, G; Hedner, J; Hmissi, A; Mangialaio, S; Pillar, G; Polo, O; Zammit, G | 1 |
| Akasofu, S; Beuckmann, CT; Nakagawa, M; Suzuki, M; Ueno, T | 1 |
| Batki, SL; Hlavin, J; Inslicht, SS; Kilduff, TS; Metzler, TJ; Morairty, SR; Motraghi, T; Neylan, TC; O'Donovan, A; Richards, A; Ruoff, LM; Samuelson, K; Sivasubramanian, M; Varbel, J | 1 |
5 trial(s) available for zolpidem and almorexant
| Article | Year |
|---|---|
Orexin receptor antagonism, a new sleep-promoting paradigm: an ascending single-dose study with almorexant.
Topics: Acetamides; Adolescent; Adult; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; GABA-A Receptor Agonists; Humans; Isoquinolines; Male; Orexin Receptors; Pyridines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sleep; Sleep Initiation and Maintenance Disorders; Wakefulness; Young Adult; Zolpidem | 2010 |
Tolerability, pharmacokinetics, and pharmacodynamics of single-dose almorexant, an orexin receptor antagonist, in healthy elderly subjects.
Topics: Acetamides; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Half-Life; Humans; Isoquinolines; Male; Middle Aged; Orexin Receptors; Pyridines; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Sleep Initiation and Maintenance Disorders; Zolpidem | 2013 |
Assessment of the abuse liability of a dual orexin receptor antagonist: a crossover study of almorexant and zolpidem in recreational drug users.
Topics: Acetamides; Adolescent; Adult; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Illicit Drugs; Isoquinolines; Male; Middle Aged; Orexin Receptor Antagonists; Orexin Receptors; Pyridines; Substance-Related Disorders; Young Adult; Zolpidem | 2014 |
Efficacy and safety of almorexant in adult chronic insomnia: a randomized placebo-controlled trial with an active reference.
Topics: Acetamides; Administration, Oral; Adolescent; Adult; Chronic Disease; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Isoquinolines; Male; Middle Aged; Orexin Receptor Antagonists; Polysomnography; Pyridines; Sleep Initiation and Maintenance Disorders; Time Factors; Treatment Outcome; Young Adult; Zolpidem | 2017 |
Acute cognitive effects of the hypocretin receptor antagonist almorexant relative to zolpidem and placebo: a randomized clinical trial.
Topics: Acetamides; Animals; Cognition; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Isoquinolines; Male; Orexin Receptors; Orexins; Psychomotor Performance; Pyridines; Young Adult; Zolpidem | 2020 |
6 other study(ies) available for zolpidem and almorexant
| Article | Year |
|---|---|
Design, synthesis, and structure-activity relationships of a series of novel N-aryl-2-phenylcyclopropanecarboxamide that are potent and orally active orexin receptor antagonists.
Topics: Animals; Cyclopropanes; Drug Design; Humans; Male; Mice; Mice, Inbred C57BL; Models, Molecular; Orexin Receptor Antagonists; Orexin Receptors; Sleep; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship | 2014 |
Differential effects of the dual orexin receptor antagonist almorexant and the GABA(A)-α1 receptor modulator zolpidem, alone or combined with ethanol, on motor performance in the rat.
Topics: Acetamides; Animals; Drug Interactions; Drug Therapy, Combination; Ethanol; GABA-A Receptor Agonists; Isoquinolines; Male; Motor Activity; Orexin Receptors; Pyridines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, GABA-A; Receptors, Neuropeptide; Zolpidem | 2011 |
Homeostatic sleep pressure is the primary factor for activation of cortical nNOS/NK1 neurons.
Topics: Acetamides; Animals; Cerebral Cortex; Homeostasis; Isoquinolines; Male; Neurons; Nitric Oxide Synthase Type I; Pyridines; Rats; Receptors, Neurokinin-1; Sleep Deprivation; Sleep Stages; Zolpidem | 2015 |
Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain.
Topics: Acetamides; Adenosine; Animals; Antibodies, Monoclonal; Basal Forebrain; Butyric Acid; Cholinergic Neurons; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Signaling Peptides and Proteins; Isoquinolines; Male; Neuropeptides; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Pyridines; Rats; Rats, Sprague-Dawley; Ribosome Inactivating Proteins, Type 1; Saporins; Sleep; Synaptic Transmission; Wakefulness; Zolpidem | 2016 |
The Dual Hypocretin Receptor Antagonist Almorexant is Permissive for Activation of Wake-Promoting Systems.
Topics: Acetamides; Animals; Brain; Cholinergic Neurons; Electroencephalography; Electromyography; Histamine; Isoquinolines; Male; Neurons; Orexin Receptor Antagonists; Orexins; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Serotonergic Neurons; Sleep Stages; Wakefulness; Zolpidem | 2016 |
Preclinical in vivo characterization of lemborexant (E2006), a novel dual orexin receptor antagonist for sleep/wake regulation.
Topics: Acetamides; Adrenocorticotropic Hormone; Animals; Female; Hypnotics and Sedatives; Isoquinolines; Male; Mice; Mice, Inbred C57BL; Orexin Receptor Antagonists; Orexin Receptors; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sleep Initiation and Maintenance Disorders; Sleep, REM; Wakefulness; Zolpidem | 2019 |