Page last updated: 2024-08-25

zoledronic acid and ym 529

zoledronic acid has been researched along with ym 529 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (70.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martin, MB; Oldfield, E; Szabo, CM1
Araujo, FG; Chan, JM; Ling, Y; Moreno, SN; Odeh, S; Oldfield, E; Sahota, G1
Hall, P; Hudock, MP; Leon, A; Liu, L; Morita, CT; Oldfield, E; Puan, KJ; Studer, D; Yang, Y; Yin, F1
Cao, R; Chang, TH; Chen, CK; Guo, RT; Hudock, MP; Jeng, WY; Ko, TP; Kuo, CJ; Liang, PH; Oldfield, E; Song, Y; Wang, AH; Yin, F; Zhang, Y1
Axelson, J; Cao, R; Chang, SC; Chang, TH; Guo, RT; Hudock, MP; K-M Chen, C; Ko, TP; Kumar, A; Liang, PH; No, JH; Oldfield, E; Song, Y; Wang, AH; Zhang, Y1
Berghuis, AM; Chiu, W; Cho, H; De Schutter, JW; Gritzalis, D; Lacbay, CM; Lin, YS; Park, J; Tsantrizos, YS; Zielinski, M1
Bhuiyan, NH; Holstein, SA; Varney, ML; Wiemer, DF1
Barnett, BL; Deprèle, S; Ebetino, FH; Evdokimov, A; Hogan, JM; Kashemirov, BA; McKenna, CE1
Matsumoto, T1
Chen, X; Liu, C; Yang, Y; Zhang, Y; Zhong, D; Zhou, L1

Other Studies

10 other study(ies) available for zoledronic acid and ym 529

ArticleYear
An investigation of bone resorption and Dictyostelium discoideum growth inhibition by bisphosphonate drugs.
    Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14

    Topics: Alkyl and Aryl Transferases; Animals; Bone Resorption; Crystallography, X-Ray; Dictyostelium; Diphosphonates; Enzyme Inhibitors; Geranyltranstransferase; Humans; Inhibitory Concentration 50; Models, Molecular; Quantitative Structure-Activity Relationship; Rats

2002
Bisphosphonate inhibitors of Toxoplasma gondi growth: in vitro, QSAR, and in vivo investigations.
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: Aldose-Ketose Isomerases; Alkyl and Aryl Transferases; Animals; Antiprotozoal Agents; Cell Line; Diphosphonates; Fosfomycin; Geranyltranstransferase; Humans; Mice; Models, Molecular; Multienzyme Complexes; Oxidoreductases; Quantitative Structure-Activity Relationship; Toxoplasma; Toxoplasmosis

2005
Isoprenoid biosynthesis as a drug target: bisphosphonate inhibition of Escherichia coli K12 growth and synergistic effects of fosmidomycin.
    Journal of medicinal chemistry, 2006, Dec-14, Volume: 49, Issue:25

    Topics: Anti-Bacterial Agents; Cluster Analysis; Diphosphonates; Drug Synergism; Escherichia coli K12; Fosfomycin; Gene Expression; Geranyltranstransferase; Models, Molecular; Oligonucleotide Array Sequence Analysis; Quantitative Structure-Activity Relationship; Terpenes

2006
Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Jun-12, Volume: 104, Issue:24

    Topics: Alkyl and Aryl Transferases; Binding Sites; Crystallography, X-Ray; Dimerization; Diphosphates; Diphosphonates; Diterpenes; Farnesyltranstransferase; Hydrophobic and Hydrophilic Interactions; Isoenzymes; Ligands; Models, Chemical; Models, Molecular; Molecular Structure; Polyisoprenyl Phosphates; Protein Structure, Secondary; Saccharomyces cerevisiae; Sesquiterpenes; Stereoisomerism; Substrate Specificity; Transferases

2007
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Antineoplastic Agents; Crystallography, X-Ray; Diphosphonates; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Farnesyltranstransferase; Humans; K562 Cells; Magnetic Resonance Spectroscopy; Models, Molecular; Quantitative Structure-Activity Relationship

2008
Probing the molecular and structural elements of ligands binding to the active site versus an allosteric pocket of the human farnesyl pyrophosphate synthase.
    Bioorganic & medicinal chemistry letters, 2015, Mar-01, Volume: 25, Issue:5

    Topics: Allosteric Site; Catalytic Domain; Diphosphonates; Geranyltranstransferase; Humans; Ligands; Magnesium; Molecular Docking Simulation; Protein Binding

2015
Novel benzimidazole phosphonates as potential inhibitors of protein prenylation.
    Bioorganic & medicinal chemistry letters, 2019, 12-15, Volume: 29, Issue:24

    Topics: Benzimidazoles; Humans; Organophosphonates; Protein Prenylation

2019
Farnesyl pyrophosphate synthase enantiospecificity with a chiral risedronate analog, [6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl(hydroxy)methylene]bis(phosphonic acid) (NE-10501): Synthetic, structural, and modeling studies.
    Bioorganic & medicinal chemistry letters, 2008, May-01, Volume: 18, Issue:9

    Topics: Algorithms; Binding Sites; Bone Density Conservation Agents; Carcinoma; Computer Simulation; Crystallography, X-Ray; Diphosphonates; Enzyme Inhibitors; Etidronic Acid; Farnesyltranstransferase; Humans; Imidazoles; Inhibitory Concentration 50; Magnesium; Models, Chemical; Organophosphonates; Pyridines; Risedronic Acid; Stereoisomerism; Structure-Activity Relationship; Zoledronic Acid

2008
[New bisphosphonates and trends in drug therapy for osteoporosis: preface].
    Clinical calcium, 2009, Volume: 19, Issue:1

    Topics: Alendronate; Bone Density Conservation Agents; Clinical Trials as Topic; Diphosphonates; Etidronic Acid; Evidence-Based Medicine; Humans; Imidazoles; Osteoporosis; Risedronic Acid; Zoledronic Acid

2009
On-cartridge derivatization coupled with solid-phase extraction for the ultra-sensitive determination of minodronic acid in human plasma by LC-MS/MS method.
    Journal of pharmaceutical and biomedical analysis, 2015, Oct-10, Volume: 114

    Topics: Anticoagulants; Area Under Curve; Calibration; Chromatography, Liquid; Diazomethane; Diphosphonates; Humans; Hydrogen-Ion Concentration; Imidazoles; Limit of Detection; Mass Spectrometry; Methylation; Nitrogen; Reproducibility of Results; Risedronic Acid; Solid Phase Extraction; Tandem Mass Spectrometry; Trimethylsilyl Compounds; Zoledronic Acid

2015