Page last updated: 2024-08-25

zoledronic acid and pravastatin

zoledronic acid has been researched along with pravastatin in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's10 (58.82)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cadiñanos, J; Cau, P; Cobo, J; de Carlos, F; Foray, N; Freije, JM; Lévy, N; López-Otín, C; Navarro, CL; Osorio, FG; Pereira, S; Suárez, MF; Ugalde, AP; Varela, I1
Gruenbaum, Y; Meshorer, E1
Endo, Y; Funayama, H; Kawamura, H; Kumamoto, H; Kuroishi, T; Oizumi, T; Sasaki, K; Sugawara, S; Takahashi, H; Yamaguchi, K; Yamamoto, M; Yokoyama, M1
Jiang, K1
Acín-Perez, R; Andrés, V; Cabezas-Sánchez, P; Cámara, C; Enríquez, JA; Gonzalez-Gómez, C; López-Otín, C; Luque-García, JL; Megias, D; Osorio, FG; Rivera-Torres, J1
Blondel, S; Cordette, V; de Sandre-Giovannoli, A; Djabali, K; Egesipe, AL; Jaskowiak, AL; Laabi, Y; Le Corf, A; Levy, N; Martinat, C; Navarro, C; Nissan, X; Peschanski, M1
Brazier, J; Brown, WT; Campbell, SE; D'Agostino, RB; Gordon, LB; Kieran, MW; Kleinman, ME; Massaro, J1
Hisama, FM; Martin, GM; Oshima, J1
Badens, C; Bonello-Palot, N; Bourgeois, P; Dignat-George, F; Levy, N; Robert, S; Sabatier, F; Simoncini, S1
Cleveland, RH; D'Agostino, RB; Dowton, AA; Gerhard-Herman, M; Gordon, CM; Gordon, LB; Greer, MM; Huh, SY; Kieran, MW; Kleinman, ME; Liang, MG; Littlefield, K; Massaro, J; Miller, DT; Nazarian, A; Quinn, N; Shappell, H; Silvera, VM; Smoot, LB; Snyder, BD; Ullrich, NJ1
Baltrusaitis, K; Braddock, DT; Cleveland, RH; D'Agostino, RB; Gordon, CM; Gordon, LB; Kieran, MW; Kleinman, ME; Li, X; Liang, MG; Massaro, J; Snyder, B; Walters, M1
Cabral, WA; Collins, FS; Cubria, MB; DuBose, A; Erdos, MR; Kamalapathy, P; Karim, L; Masoudi, A; Nazarian, A; Oftadeh, R; Snyder, BD; Suarez, S1
Al Choboq, J; Berthel, E; Devic, C; Ferlazzo, ML; Foray, N; Granzotto, A; Moulay Lakhdar, I; Sonzogni, L; Thariat, J1
Du, G; Fan, D; Han, G; Li, H; Li, R; Liu, D; Liu, Q; Song, C; Tao, L; Zhang, M1

Reviews

1 review(s) available for zoledronic acid and pravastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for zoledronic acid and pravastatin

ArticleYear
Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome.
    Circulation, 2016, Jul-12, Volume: 134, Issue:2

    Topics: Bone and Bones; Carotid Arteries; Child, Preschool; Diphosphonates; Drug Therapy, Combination; Female; Humans; Imidazoles; Infant; Male; Piperidines; Pravastatin; Progeria; Prospective Studies; Protein Prenylation; Pyridines; Zoledronic Acid

2016
Reduction effect of oral pravastatin on the acute phase response to intravenous zoledronic acid: protocol for a real-world prospective, placebo-controlled trial.
    BMJ open, 2022, 07-13, Volume: 12, Issue:7

    Topics: Acute-Phase Reaction; Female; Humans; Meta-Analysis as Topic; Osteoporosis; Pravastatin; Prospective Studies; Randomized Controlled Trials as Topic; Treatment Outcome; Zoledronic Acid

2022

Other Studies

14 other study(ies) available for zoledronic acid and pravastatin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.
    Nature medicine, 2008, Volume: 14, Issue:7

    Topics: Aging, Premature; Animals; Bone Density Conservation Agents; Diphosphonates; Drug Therapy, Combination; Enzyme Inhibitors; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Immunohistochemistry; Mice; Mice, Knockout; Models, Animal; Pravastatin; Prenylation; Zoledronic Acid

2008
Rejuvenating premature aging.
    Nature medicine, 2008, Volume: 14, Issue:7

    Topics: Animals; Bone Density Conservation Agents; Cell Nucleus; Diphosphonates; Disease Models, Animal; Drug Therapy, Combination; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lamin Type A; Longevity; Mice; Mice, Knockout; Nuclear Proteins; Pravastatin; Prenylation; Progeria; Protein Precursors; Tumor Suppressor Protein p53; Zoledronic Acid

2008
Inhibition of necrotic actions of nitrogen-containing bisphosphonates (NBPs) and their elimination from bone by etidronate (a non-NBP): a proposal for possible utilization of etidronate as a substitution drug for NBPs.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2010, Volume: 68, Issue:5

    Topics: Alendronate; Animals; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Ear, External; Etidronic Acid; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Inflammation Mediators; Injections, Intraperitoneal; Injections, Subcutaneous; Interleukin-1; Male; Mice; Mice, Inbred BALB C; Necrosis; Osteonecrosis; Osteosclerosis; Pamidronate; Pravastatin; Radionuclide Imaging; Radiopharmaceuticals; Risedronic Acid; Technetium; Tibia; Time Factors; Zoledronic Acid

2010
Drug development for progeria yields insights into normal aging.
    Nature medicine, 2013, Volume: 19, Issue:5

    Topics: Aging; Child; Clinical Trials as Topic; Diphosphonates; Drug Discovery; Humans; Imidazoles; Lamin Type A; Mutation; Piperidines; Pravastatin; Progeria; Pyridines; Time Factors; Zoledronic Acid

2013
Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture.
    Journal of proteomics, 2013, Oct-08, Volume: 91

    Topics: Adenosine Triphosphate; Adolescent; Amino Acids; Animals; Child; Diphosphonates; Female; Fibroblasts; Galactose; Gene Expression Regulation; Glucose; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lamin Type A; Male; Methionine; Mice; Mitochondria; Mutation; Nuclear Proteins; Oxygen Consumption; Pravastatin; Progeria; Protein Precursors; Proteomics; Skin; Zoledronic Acid

2013
Induced pluripotent stem cells reveal functional differences between drugs currently investigated in patients with hutchinson-gilford progeria syndrome.
    Stem cells translational medicine, 2014, Volume: 3, Issue:4

    Topics: Animals; Anticholesteremic Agents; Bone Density Conservation Agents; Cell Differentiation; Cell Proliferation; Child; Child, Preschool; Diphosphonates; Female; Humans; Imidazoles; Induced Pluripotent Stem Cells; Infant; Lamin Type A; Male; Mice; Nuclear Proteins; Osteoblasts; Pravastatin; Prenylation; Progeria; Protein Precursors; Zoledronic Acid

2014
Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.
    Circulation, 2014, Jul-01, Volume: 130, Issue:1

    Topics: Adolescent; Adult; Alkyl and Aryl Transferases; Atherosclerosis; Cause of Death; Child; Child, Preschool; Clinical Trials as Topic; Cohort Studies; Dimethylallyltranstransferase; Diphosphonates; Drug Therapy, Combination; Female; Genes, Dominant; Genotype; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Kaplan-Meier Estimate; Lamin Type A; Male; Multicenter Studies as Topic; Nuclear Proteins; Piperidines; Pravastatin; Progeria; Proportional Hazards Models; Protein Precursors; Protein Prenylation; Pyridines; Treatment Outcome; Young Adult; Zoledronic Acid

2014
An encouraging progress report on the treatment of progeria and its implications for atherogenesis.
    Circulation, 2014, Jul-01, Volume: 130, Issue:1

    Topics: Diphosphonates; Female; Humans; Imidazoles; Lamin Type A; Male; Nuclear Proteins; Piperidines; Pravastatin; Progeria; Protein Precursors; Protein Prenylation; Pyridines; Zoledronic Acid

2014
Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment.
    Atherosclerosis, 2014, Volume: 237, Issue:1

    Topics: Atazanavir Sulfate; Cell Adhesion; Cell Proliferation; Cells, Cultured; Cellular Senescence; Diphosphonates; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; Lamin Type A; Microscopy, Fluorescence; Monocytes; Neovascularization, Pathologic; Nuclear Proteins; Oligopeptides; Pravastatin; Progeria; Protein Precursors; Pyridines; Umbilical Cord; Umbilical Veins; Zoledronic Acid

2014
Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome.
    Bone, 2019, Volume: 125

    Topics: Calcinosis; Calcium; Child; Child, Preschool; Creatinine; Female; Fibroblast Growth Factor-23; Humans; In Vitro Techniques; Lamin Type A; Male; Parathyroid Hormone; Piperidines; Pravastatin; Progeria; Pyridines; Zoledronic Acid

2019
Evaluation of musculoskeletal phenotype of the G608G progeria mouse model with lonafarnib, pravastatin, and zoledronic acid as treatment groups.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 06-02, Volume: 117, Issue:22

    Topics: Aging; Animals; Bone and Bones; Bone Density Conservation Agents; Cartilage; Disease Models, Animal; Femur; Glycosaminoglycans; Joints; Lamin Type A; Mice; Mice, Transgenic; Mutation; Osteoarthritis; Phenotype; Piperidines; Pravastatin; Progeria; Protein Processing, Post-Translational; Pyridines; X-Ray Microtomography; Zoledronic Acid

2020
Fibroblasts from Retinoblastoma Patients Show Radiosensitivity Linked to Abnormal Localization of the ATM Protein.
    Current eye research, 2021, Volume: 46, Issue:4

    Topics: Anticholesteremic Agents; Ataxia Telangiectasia Mutated Proteins; Bone Density Conservation Agents; Cell Line; DNA Breaks, Double-Stranded; DNA Repair; Drug Combinations; Fibroblasts; Humans; Pravastatin; Radiation Dosage; Radiation Tolerance; Retinal Neoplasms; Retinoblastoma; Retinoblastoma Binding Proteins; Skin; Ubiquitin-Protein Ligases; X-Rays; Zoledronic Acid

2021