zoledronic acid has been researched along with paclitaxel in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 14 (53.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Boissier, S; Clézardin, P; Colombel, M; Delaissé, JM; Delmas, P; Ebetino, FH; Ferreras, M; Magnetto, S; Peyruchaud, O | 1 |
| Coleman, RE; Croucher, PI; Jagdev, SP; Rostami-H, A; Shipman, CM | 1 |
| Potter, DM | 1 |
| Bielawski, KP; Bosse, U; Schlotter, CM; Vogt, U | 1 |
| Fan, D; Fidler, IJ; He, J; Kim, SJ; Langley, RR; Mathew, P; Uehara, H; Yazici, S | 1 |
| Duan, X; Guan, H; Kleinerman, ES; Zhou, Z | 1 |
| Conroy, M; Cree, IA; Fernando, A; Knight, LA; Kurbacher, CM; Polak, M | 1 |
| Inoue, K; Iwase, H; Kawazoe, T; Nagamoto, N; Nakahara, O; Ohsako, T; Sakamoto, N; Yamamoto, Y; Yoshida, Y | 1 |
| Coleman, RE; Evans, CA; Holen, I; Neville-Webbe, HL | 1 |
| Chen, HQ; He, WZ; Li, ZM; Liao, ML; Lu, S; Wang, JJ; Xiang, JQ; Zhang, J; Zhou, XY; Zhou, Z | 1 |
| Brown, HK; Brown, NJ; Coleman, RE; Cross, SS; Evans, A; Holen, I; Lefley, DV; Michailidou, M | 1 |
| Ding, Y; Yang, L; Zhang, ZY; Zhou, LQ | 1 |
| Gődény, M; Láng, I; Nagy, T; Rubovszky, G; Szász, A | 1 |
| Huang, WL; Li, XY; Lin, SL; Lin, W; Lin, WZ; Lin, YC; Wang, HB | 1 |
| Enomoto, T; Kikuchi, M; Kosaka, Y; Minatani, N; Nishimiya, H; Sengoku, N; Tanino, H; Waraya, M; Watanabe, M | 1 |
| Fu, J; Ge, XY; Jiang, Y; Li, SL; Yang, LQ; Yang, WW | 1 |
| Aslan, B; Calin, G; Dalton, HJ; Del C Monroig, P; Fernandez-de Thomas, RJ; Fuentes-Mattei, E; Gonzalez-Villasana, V; Ivan, C; Kahraman, N; Kanlikilicer, P; Lopez-Berestein, G; Ozpolat, B; Pradeep, S; Previs, RA; Rodriguez-Aguayo, C; Sood, AK; Velazquez-Torres, G; Wang, H | 1 |
| Abe, Y; Hirai, R; Ikeda, E; Kashima, H; Kuroda, M; Kurosaki, T; Miyahara, K; Moriyama, S; Takagi, S; Tsuji, H; Yamano, T; Yoshitomi, S | 1 |
| Gui, Q; Li, D; Xia, S; Xu, C; Yu, S; Zhuang, L | 1 |
| Akazawa, K; Hasegawa, Y; Hayashi, M; Horiguchi, J; Ishikawa, T; Kohno, N; Miura, D; Tanino, H | 1 |
| Ju, W; Pan, Q; Xu, J | 1 |
1 review(s) available for zoledronic acid and paclitaxel
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for zoledronic acid and paclitaxel
| Article | Year |
|---|---|
Survival outcomes of neoadjuvant chemotherapy with zoledronic acid for HER2-negative breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Diphosphonates; Disease-Free Survival; Epirubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Imidazoles; Mastectomy, Segmental; Neoadjuvant Therapy; Paclitaxel; Postmenopause; Receptor, ErbB-2; Zoledronic Acid | 2017 |
24 other study(ies) available for zoledronic acid and paclitaxel
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Bone Neoplasms; Breast Neoplasms; Cell Adhesion; Cell Cycle; Cell Movement; Clodronic Acid; Collagen; Diphosphonates; Dose-Response Relationship, Drug; Drug Combinations; Flow Cytometry; Fluorometry; Humans; Ibandronic Acid; Imidazoles; Laminin; Male; Matrix Metalloproteinases; Neoplasm Invasiveness; Neoplasm Metastasis; Paclitaxel; Prostatic Neoplasms; Proteoglycans; Pyridines; Pyridinium Compounds; Tumor Cells, Cultured; Zinc; Zoledronic Acid | 2000 |
The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Count; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imidazoles; Mevalonic Acid; Paclitaxel; Time Factors; Tumor Cells, Cultured; Zoledronic Acid | 2001 |
Adaptive dose finding for phase I clinical trials of drugs used for chemotherapy of cancer.
Topics: Algorithms; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Calcitriol; Camptothecin; Carboplatin; Clinical Trials, Phase I as Topic; Computer Simulation; Dexamethasone; Diphosphonates; Docetaxel; Dose-Response Relationship, Drug; Humans; Imidazoles; Maximum Tolerated Dose; Monte Carlo Method; Paclitaxel; Taxoids; Zoledronic Acid | 2002 |
Breast tumour growth inhibition in vitro through the combination of cyclophosphamide/metotrexate/5-fluorouracil, epirubicin/cyclophosphamide, epirubicin/paclitaxel, and epirubicin/docetaxel with the bisphosphonates ibandronate and zoledronic acid.
Topics: Adenocarcinoma, Mucinous; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclophosphamide; Diphosphonates; Docetaxel; Drug Synergism; Epirubicin; Female; Fluorouracil; Humans; Ibandronic Acid; Imidazoles; In Vitro Techniques; Methotrexate; Middle Aged; Neoplasm Invasiveness; Neoplasms, Ductal, Lobular, and Medullary; Paclitaxel; Taxoids; Zoledronic Acid | 2004 |
Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Bone and Bones; Bone Neoplasms; Cell Line, Tumor; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imatinib Mesylate; Imidazoles; Immunohistochemistry; Male; Mice; Mice, Nude; Osteoclasts; Paclitaxel; Piperazines; Prostatic Neoplasms; Pyrimidines; Zoledronic Acid | 2005 |
Zoledronic acid inhibits primary bone tumor growth in Ewing sarcoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Bone Density Conservation Agents; Bone Neoplasms; Cell Proliferation; Diphosphonates; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Glycoproteins; Humans; Imidazoles; Immunoenzyme Techniques; Mice; Mice, Nude; Osteoclasts; Osteoprotegerin; Paclitaxel; Radiography; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; Sarcoma, Ewing; Zoledronic Acid | 2005 |
Pilot studies of the effect of zoledronic acid (Zometa) on tumor-derived cells ex vivo in the ATP-based tumor chemosensitivity assay.
Topics: Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Alendronate; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Caspase 3; Caspase 7; Caspases; Cell Line, Tumor; Cell Survival; Cisplatin; Clodronic Acid; Diphosphonates; Energy Metabolism; Female; Humans; Imidazoles; Inhibitory Concentration 50; Lung Neoplasms; Male; Melanoma; Middle Aged; Neoplasms; Neoplasms, Unknown Primary; Ovarian Neoplasms; Paclitaxel; Tumor Cells, Cultured; Zoledronic Acid | 2005 |
[Two cases of stage IV breast cancer with severe hypercalcemia].
Topics: Adult; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Diphosphonates; Drug Administration Schedule; Female; Goserelin; Humans; Hypercalcemia; Imidazoles; Leuprolide; Lymph Nodes; Lymphatic Metastasis; Paclitaxel; Quality of Life; Tamoxifen; Zoledronic Acid | 2006 |
Mechanisms of the synergistic interaction between the bisphosphonate zoledronic acid and the chemotherapy agent paclitaxel in breast cancer cells in vitro.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; BRCA1 Protein; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Imidazoles; Mevalonic Acid; Mutation; Paclitaxel; Signal Transduction; Time Factors; Zoledronic Acid | 2006 |
Synergistic inhibitory activity of zoledronate and paclitaxel on bone metastasis in nude mice.
Topics: Animals; Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; bcl-X Protein; Bone Density Conservation Agents; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Collagen Type I; Diphosphonates; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Humans; Imidazoles; Immunoenzyme Techniques; Incidence; Lung Neoplasms; Mice; Mice, Nude; Paclitaxel; Peptides; Proto-Oncogene Proteins c-bcl-2; Survival Rate; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zoledronic Acid | 2008 |
Microvascular endothelial cell responses in vitro and in vivo: modulation by zoledronic acid and paclitaxel?
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; Diphosphonates; Dose-Response Relationship, Drug; Drug Synergism; Endothelial Cells; Humans; Imidazoles; Male; Mice; Mice, Nude; Microvessels; Neovascularization, Physiologic; Paclitaxel; Protein Prenylation; rap1 GTP-Binding Proteins; Time Factors; Zoledronic Acid | 2010 |
[Study of sequence-dependent in vitro effects of zoledronic acid and paclitaxel upon DU145 prostate cancer cells].
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Humans; Imidazoles; Male; Paclitaxel; Prostatic Neoplasms; Zoledronic Acid | 2010 |
Successful treatment of solitary bone metastasis of non-small cell lung cancer with bevacizumab and hyperthermia.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bone Neoplasms; Carboplatin; Carcinoma, Non-Small-Cell Lung; Combined Modality Therapy; Diphosphonates; Humans; Hyperthermia, Induced; Imidazoles; Lung Neoplasms; Male; Middle Aged; Paclitaxel; Zoledronic Acid | 2013 |
[Study of sequence-dependent in vitro effects of zoledronic acid and paclitaxel upon human nasopharyngeal carcinoma cell line HNE1].
Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Diphosphonates; Humans; Imidazoles; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Paclitaxel; Zoledronic Acid | 2012 |
[A case of facial nerve palsy induced by nab-paclitaxel].
Topics: Albumins; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Diphosphonates; Facial Paralysis; Female; Humans; Imidazoles; Middle Aged; Paclitaxel; Zoledronic Acid | 2013 |
Reactive oxygen species and autophagy associated apoptosis and limitation of clonogenic survival induced by zoledronic acid in salivary adenoid cystic carcinoma cell line SACC-83.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Blotting, Western; Bone Density Conservation Agents; Carcinoma, Adenoid Cystic; Cell Cycle; Cell Proliferation; Cisplatin; Diphosphonates; Drug Therapy, Combination; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Imidazoles; Mice; Mice, Inbred BALB C; Mice, Nude; Paclitaxel; Reactive Oxygen Species; Salivary Gland Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zoledronic Acid | 2014 |
Rac1/Pak1/p38/MMP-2 Axis Regulates Angiogenesis in Ovarian Cancer.
Topics: Albumins; Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Diphosphonates; Female; High-Throughput Screening Assays; Humans; Imidazoles; Immunohistochemistry; Matrix Metalloproteinase 2; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms; p21-Activated Kinases; p38 Mitogen-Activated Protein Kinases; Paclitaxel; rac1 GTP-Binding Protein; Signal Transduction; Transfection; Xenograft Model Antitumor Assays; Zoledronic Acid | 2015 |
[Two cases of dural metastasis of breast cancer].
Topics: Antineoplastic Agents, Phytogenic; Bone Density Conservation Agents; Bone Neoplasms; Breast Neoplasms; Chemoradiotherapy; Diphosphonates; Female; Humans; Imidazoles; Magnetic Resonance Imaging; Middle Aged; Paclitaxel; Zoledronic Acid | 2014 |
Urinary N telopeptide levels in predicting the anti-nociceptive responses of zoledronic acid and paclitaxel in a rat model of bone metastases.
Topics: Acid Sensing Ion Channels; Analgesics; Animals; Biomarkers; Bone Neoplasms; Cell Line, Tumor; Collagen Type I; Diphosphonates; Drug Evaluation, Preclinical; Female; Ganglia, Spinal; Hyperalgesia; Imidazoles; Neoplasm Transplantation; Osteoclasts; Paclitaxel; Pain; Peptides; Proto-Oncogene Proteins c-fos; Rats, Wistar; Spinal Cord; Zoledronic Acid | 2015 |
Ras inhibition by zoledronic acid effectively sensitizes cervical cancer to chemotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Doxorubicin; Drug Synergism; Female; Humans; Male; Mice; Mice, SCID; Paclitaxel; Prenylation; Protein Processing, Post-Translational; ras Proteins; Tumor Cells, Cultured; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays; Zoledronic Acid | 2019 |