zoapatanol has been researched along with trimethylsilyl-bromide* in 1 studies
1 other study(ies) available for zoapatanol and trimethylsilyl-bromide
Article | Year |
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Total synthesis of natural (+)-(2's,3'r)-zoapatanol.
[reaction: see text] (+)-Zoapatanol was synthesized by using four key-steps: a Suzuki cross-coupling to prepare a (Z)-alpha,beta-unsaturated ester followed by an enantioselective dihydroxylation to control the C2' and C3' stereocenters, an intramolecular Horner-Wadsworth-Emmons olefination to construct the oxepane ring, and a chemoselective nucleophilic addition/Birch reduction process of a Weinreb amide to introduce simultaneously the beta,gamma-unsaturated ketone on the side-chain and regenerate alcohols from benzyl ethers. Topics: Biological Factors; Ketones; Oxepins; Oxidation-Reduction; Stereoisomerism; Trimethylsilyl Compounds | 2004 |