zoapatanol and trimethylsilyl-bromide

zoapatanol has been researched along with trimethylsilyl-bromide* in 1 studies

Other Studies

1 other study(ies) available for zoapatanol and trimethylsilyl-bromide

Article	Year
Total synthesis of natural (+)-(2's,3'r)-zoapatanol. Organic letters, 2004, Jun-24, Volume: 6, Issue:13 [reaction: see text] (+)-Zoapatanol was synthesized by using four key-steps: a Suzuki cross-coupling to prepare a (Z)-alpha,beta-unsaturated ester followed by an enantioselective dihydroxylation to control the C2' and C3' stereocenters, an intramolecular Horner-Wadsworth-Emmons olefination to construct the oxepane ring, and a chemoselective nucleophilic addition/Birch reduction process of a Weinreb amide to introduce simultaneously the beta,gamma-unsaturated ketone on the side-chain and regenerate alcohols from benzyl ethers. Topics: Biological Factors; Ketones; Oxepins; Oxidation-Reduction; Stereoisomerism; Trimethylsilyl Compounds	2004

Article

Year

Total synthesis of natural (+)-(2's,3'r)-zoapatanol.

Organic letters, 2004, Jun-24, Volume: 6, Issue:13

[reaction: see text] (+)-Zoapatanol was synthesized by using four key-steps: a Suzuki cross-coupling to prepare a (Z)-alpha,beta-unsaturated ester followed by an enantioselective dihydroxylation to control the C2' and C3' stereocenters, an intramolecular Horner-Wadsworth-Emmons olefination to construct the oxepane ring, and a chemoselective nucleophilic addition/Birch reduction process of a Weinreb amide to introduce simultaneously the beta,gamma-unsaturated ketone on the side-chain and regenerate alcohols from benzyl ethers.

Topics: Biological Factors; Ketones; Oxepins; Oxidation-Reduction; Stereoisomerism; Trimethylsilyl Compounds

2004