zn(ii)-phthalocyanine and 1-2-oleoylphosphatidylcholine

zn(ii)-phthalocyanine has been researched along with 1-2-oleoylphosphatidylcholine* in 1 studies

Other Studies

1 other study(ies) available for zn(ii)-phthalocyanine and 1-2-oleoylphosphatidylcholine

Article	Year
Interaction between zinc(II)-phthalocyanine-containing liposomes and human low density lipoprotein. Journal of photochemistry and photobiology. B, Biology, 1994, Volume: 23, Issue:2-3 The interaction of human low density lipoprotein (LDL) and small unilamellar liposomes containing the photosensitiser zinc(II)-phthalocyanine (Zn-Pc) was studied in vitro to determine if Zn-Pc could be directly incorporated into the lipoprotein in the absence of other serum components. Incubation of LDL with increasing concentrations of liposomes resulted in a progressive increase in the net negative charge of LDL as determined by agarose gel electrophoresis and both Zn-Pc and liposomal phospholipid were incorporated into the modified LDL particles. Gel chromatography experiments indicated an increase in the molecular mass of modified LDL and immunoaffinity chromatography provided evidence that apoprotein B epitopes on modified LDL were unable to bind to antibody. The study indicated that the liposomal components could be selectively incorporated into LDL by a process that did not appear to involve either aggregation or fusion of particles. Topics: Carbon Radioisotopes; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Agar Gel; Humans; Indoles; Isoindoles; Lipoproteins, LDL; Liposomes; Organometallic Compounds; Phosphatidylcholines; Zinc; Zinc Compounds	1994

Article

Year

Interaction between zinc(II)-phthalocyanine-containing liposomes and human low density lipoprotein.

Journal of photochemistry and photobiology. B, Biology, 1994, Volume: 23, Issue:2-3

The interaction of human low density lipoprotein (LDL) and small unilamellar liposomes containing the photosensitiser zinc(II)-phthalocyanine (Zn-Pc) was studied in vitro to determine if Zn-Pc could be directly incorporated into the lipoprotein in the absence of other serum components. Incubation of LDL with increasing concentrations of liposomes resulted in a progressive increase in the net negative charge of LDL as determined by agarose gel electrophoresis and both Zn-Pc and liposomal phospholipid were incorporated into the modified LDL particles. Gel chromatography experiments indicated an increase in the molecular mass of modified LDL and immunoaffinity chromatography provided evidence that apoprotein B epitopes on modified LDL were unable to bind to antibody. The study indicated that the liposomal components could be selectively incorporated into LDL by a process that did not appear to involve either aggregation or fusion of particles.

Topics: Carbon Radioisotopes; Chromatography, Affinity; Chromatography, Ion Exchange; Electrophoresis, Agar Gel; Humans; Indoles; Isoindoles; Lipoproteins, LDL; Liposomes; Organometallic Compounds; Phosphatidylcholines; Zinc; Zinc Compounds

1994