zm 241385 has been researched along with sch 58261 in 12 studies
| Studies (zm 241385) | Trials (zm 241385) | Recent Studies (post-2010) (zm 241385) | Studies (sch 58261) | Trials (sch 58261) | Recent Studies (post-2010) (sch 58261) |
|---|---|---|---|---|---|
| 401 | 3 | 124 | 46 | 0 | 14 |
| Protein | Taxonomy | zm 241385 (IC50) | sch 58261 (IC50) |
|---|---|---|---|
| Adenosine receptor A2a | Homo sapiens (human) | 0.026 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Daly, JW; Jacobson, KA; Melman, N; Padgett, WL; Shi, D; Siddiqi, SM; van Rhee, AM | 1 |
| Dionisotti, S; Fredholm, BB; Gessi, S; Irenius, E; Ongini, E | 1 |
| Beukers, MW; Brouwer, J; den Dulk, H; Ijzerman, AP; van Tilburg, EW | 1 |
| Guba, W; Nettekoven, M; Püllmann, B; Riemer, C; Schmitt, S | 1 |
| Chen, L; Engber, T; Grant, D; Hetu, G; Huang, C; Jin, X; Kumaravel, G; Peng, B; Petter, RC; Phadke, D; Reilly, J; Smits, G; Tam, S; Vu, CB; Zhang, J | 1 |
| Engber, T; Grant, D; Hetu, G; Huang, C; Jin, X; Kumaravel, G; Pan, D; Peng, B; Petter, RC; Phadke, D; Reilly, J; Smits, G; Tam, S; Vu, CB | 1 |
| Ayyub, E; Chang, HX; Dowling, JE; Engber, T; Haque, S; Jin, X; Kumaravel, G; Petter, RC; Phadke, D; van Vloten, K; Vessels, JT; Wang, J | 1 |
| Gao, ZG; Jacobson, KA | 1 |
| Beukers, MW; Brussee, J; de Graaf, O; de Vries, H; Göblyös, A; Ijzerman, AP; Link, R; Mantri, M; Mulder-Krieger, T; van Veldhoven, J; von Frijtag Drabbe Künzel, JK | 1 |
| Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L | 1 |
| de Lera Ruiz, M; Lim, YH; Zheng, J | 1 |
| Gaba, S; Gupta, GD; Monga, V; Patel, R; Saini, A; Singh, G | 1 |
4 review(s) available for zm 241385 and sch 58261
| Article | Year |
|---|---|
Adenosine receptors as therapeutic targets.
Topics: Animals; Disease; Drug Therapy; Humans; Ligands; Molecular Structure; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Structure-Activity Relationship | 2006 |
Fluorescent ligands for adenosine receptors.
Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1 | 2013 |
Adenosine A2A receptor as a drug discovery target.
Topics: Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Crystallography, X-Ray; Drug Discovery; Humans; Ligands; Protein Conformation; Receptor, Adenosine A2A; Signal Transduction | 2014 |
Adenosine receptor antagonists: Recent advances and therapeutic perspective.
Topics: Dose-Response Relationship, Drug; Humans; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Structure-Activity Relationship | 2022 |
8 other study(ies) available for zm 241385 and sch 58261
| Article | Year |
|---|---|
Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists.
Topics: Animals; Binding Sites; Humans; Male; Mice; Models, Molecular; Motor Activity; Purinergic P1 Receptor Antagonists; Rats; Structure-Activity Relationship; Thiophenes | 1996 |
Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors.
Topics: Animals; Cell Line; CHO Cells; Cricetinae; Cyclic AMP; Humans; Purinergic P1 Receptor Antagonists; Pyrimidines; Quinazolines; Rats; Transfection; Triazines; Triazoles; Xanthines | 1999 |
Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.
Topics: Adenosine; Alkynes; Amino Acid Sequence; Animals; Asparagine; COS Cells; Cyclic AMP; Molecular Sequence Data; Mutation; Point Mutation; Protein Conformation; Purinergic P1 Receptor Agonists; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Sequence Homology, Amino Acid; Transfection; Tyrosine | 2000 |
Comparison of inhibitory activity of isomeric triazolopyridine derivatives towards adenosine receptor subtypes or do similar structures reveal similar bioactivities?
Topics: Binding Sites; Humans; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Purinergic P1; Structure-Activity Relationship; Triazoles | 2004 |
Piperazine derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists.
Topics: Adenosine A2 Receptor Antagonists; Administration, Oral; Animals; Antiparkinson Agents; Biological Availability; Brain; Catalepsy; Heterocyclic Compounds, 2-Ring; In Vitro Techniques; Male; Mice; Parkinsonian Disorders; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Structure-Activity Relationship; Triazines; Triazoles | 2004 |
Novel diamino derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists.
Topics: Adenosine A2 Receptor Antagonists; Administration, Oral; Animals; Antiparkinson Agents; Binding, Competitive; Biological Availability; Catalepsy; Cerebral Cortex; Combinatorial Chemistry Techniques; Diamines; In Vitro Techniques; Male; Mice; Pyrrolidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Stereoisomerism; Triazines; Triazoles | 2005 |
Synthesis of [1,2,4]triazolo[1,5-a]pyrazines as adenosine A2A receptor antagonists.
Topics: Adenosine A2 Receptor Antagonists; Animals; Brain; Cell Membrane; Disease Models, Animal; Parkinson Disease; Pyrazines; Radioligand Assay; Rats; Structure-Activity Relationship | 2005 |
2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists.
Topics: Adenosine A2 Receptor Antagonists; Amines; Animals; Cell Line; Cricetinae; Cyclic AMP; Furans; Humans; Models, Molecular; Molecular Structure; Nicotinic Acids; Nitriles; Receptor, Adenosine A2A; Structure-Activity Relationship | 2008 |