Compounds > zm 241385
Page last updated: 2024-09-05

zm 241385 and sch 442416

zm 241385 has been researched along with sch 442416 in 8 studies

Compound Research Comparison

Studies
(zm 241385)		Trials
(zm 241385)		Recent Studies (post-2010)
(zm 241385)		Studies
(sch 442416)		Trials
(sch 442416)		Recent Studies (post-2010) (sch 442416)
401312440125

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's6 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, ZG; Jacobson, KA1
Cacciari, B; Cheong, SL; Federico, S; Gao, ZG; Jacobson, KA; Klotz, KN; Moro, S; Paoletta, S; Pastorin, G; Siegel, J; Spalluto, G; Stragliotto, S1
Federico, S; Jacobson, KA; Jayasekara, PS; Kozma, E; Moro, S; Paoletta, S; Spalluto, G; Squarcialupi, L1
Cacciari, B; Ciancetta, A; Federico, S; Klotz, KN; Moro, S; Pastorin, G; Porta, N; Redenti, S; Spalluto, G1
French, SW; Khachatoorian, R; Micewicz, ED; Ruchala, P1
Cipriani, S; Galli, A; Gianfriddo, M; Giovannini, MG; Mello, T; Pedata, F; Pugliese, AM; Traini, C1
Pao, AC; Rajagopal, M1
Dimitrieva, TV; Pliyev, BK; Savchenko, VG1

Reviews

2 review(s) available for zm 241385 and sch 442416

ArticleYear
Adenosine receptors as therapeutic targets.
    Nature reviews. Drug discovery, 2006, Volume: 5, Issue:3

    Topics: Animals; Disease; Drug Therapy; Humans; Ligands; Molecular Structure; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Signal Transduction; Structure-Activity Relationship

2006
Fluorescent ligands for adenosine receptors.
    Bioorganic & medicinal chemistry letters, 2013, Jan-01, Volume: 23, Issue:1

    Topics: Boron Compounds; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Ligands; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1

2013

Other Studies

6 other study(ies) available for zm 241385 and sch 442416

ArticleYear
Synthesis and biological evaluation of a new series of 1,2,4-triazolo[1,5-a]-1,3,5-triazines as human A(2A) adenosine receptor antagonists with improved water solubility.
    Journal of medicinal chemistry, 2011, Feb-10, Volume: 54, Issue:3

    Topics: Adenosine A2 Receptor Antagonists; Animals; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Protein Binding; Protein Conformation; Radioligand Assay; Solubility; Static Electricity; Structure-Activity Relationship; Triazines; Triazoles; Water

2011
Scaffold decoration at positions 5 and 8 of 1,2,4-triazolo[1,5-c]pyrimidines to explore the antagonist profiling on adenosine receptors: a preliminary structure-activity relationship study.
    Journal of medicinal chemistry, 2014, Jul-24, Volume: 57, Issue:14

    Topics: Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Structure; Purinergic P1 Receptor Antagonists; Pyrimidines; Receptor, Adenosine A2A; Receptor, Adenosine A3; Structure-Activity Relationship; Triazoles

2014
Identification of novel small-molecule inhibitors of Zika virus infection.
    Bioorganic & medicinal chemistry letters, 2018, 02-01, Volume: 28, Issue:3

    Topics: A549 Cells; Antiviral Agents; Cell Survival; Dose-Response Relationship, Drug; Humans; Molecular Structure; Small Molecule Libraries; Structure-Activity Relationship; Zika Virus; Zika Virus Infection

2018
The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen-glucose deprivation in rat CA1 hippocampal slices.
    British journal of pharmacology, 2009, Volume: 157, Issue:5

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Astrocytes; Blotting, Western; Brain Ischemia; Cell Hypoxia; Cell Survival; Coloring Agents; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glucose; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Neurons; Neuroprotective Agents; Oxygen; Phenethylamines; Propidium; Pyrazoles; Pyrimidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Staining and Labeling; Time Factors; Triazines; Triazoles

2009
Adenosine activates a2b receptors and enhances chloride secretion in kidney inner medullary collecting duct cells.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:5

    Topics: Adenosine; Animals; Cell Line; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Kidney Medulla; Kidney Tubules, Collecting; Pyrazoles; Pyrimidines; Rats; Receptor, Adenosine A2B; Triazines; Triazoles; Xanthines

2010
Diadenosine diphosphate (Ap₂A) delays neutrophil apoptosis via the adenosine A2A receptor and cAMP/PKA pathway.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2014, Volume: 92, Issue:5

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine A2 Receptor Antagonists; Apoptosis; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dideoxyadenosine; Dinucleoside Phosphates; Humans; Neutrophils; Pyrazoles; Pyrimidines; Receptor, Adenosine A2A; Thionucleotides; Triazines; Triazoles

2014