Page last updated: 2024-09-05

zm 241385 and methoctramine

zm 241385 has been researched along with methoctramine in 2 studies

Compound Research Comparison

Studies (zm 241385)	Trials (zm 241385)	Recent Studies (post-2010) (zm 241385)	Studies (methoctramine)	Trials (methoctramine)	Recent Studies (post-2010) (methoctramine)
401	3	124	40	0	15
401	3	124	332	1	32

Protein Interaction Comparison

Protein	Taxonomy	methoctramine (IC50)
Cholinesterase	Homo sapiens (human)	0.9772
Muscarinic acetylcholine receptor M2	Homo sapiens (human)	0.0407
Acetylcholinesterase	Homo sapiens (human)	5.3703
Glutamate receptor ionotropic, NMDA 1	Homo sapiens (human)	0.138
Glutamate receptor ionotropic, NMDA 2A	Homo sapiens (human)	0.138
Carboxylic ester hydrolase	Rattus norvegicus (Norway rat)	0.9772

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO	1
Alves-Do-Prado, W; Ambiel, CR; Antônio, MB; Correia-de-Sá, P; de Paula Ramos, E	1

Other Studies

2 other study(ies) available for zm 241385 and methoctramine

Article	Year
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization. Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22 Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles	2005
Paradoxical neostigmine-induced TOFfade: on the role of presynaptic cholinergic and adenosine receptors. European journal of pharmacology, 2014, Jan-15, Volume: 723 Topics: Animals; Atropine; Cholinesterase Inhibitors; Diamines; Diaphragm; In Vitro Techniques; Male; Muscarinic Antagonists; Neostigmine; Phrenic Nerve; Pirenzepine; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Presynaptic; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles	2014

Article

Year

2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.

Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22

Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles

2005

Paradoxical neostigmine-induced TOFfade: on the role of presynaptic cholinergic and adenosine receptors.

European journal of pharmacology, 2014, Jan-15, Volume: 723

Topics: Animals; Atropine; Cholinesterase Inhibitors; Diamines; Diaphragm; In Vitro Techniques; Male; Muscarinic Antagonists; Neostigmine; Phrenic Nerve; Pirenzepine; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Presynaptic; Receptors, Purinergic P1; Synaptic Transmission; Triazines; Triazoles

2014