Page last updated: 2024-09-05

zm 241385 and ketoconazole

zm 241385 has been researched along with ketoconazole in 1 studies

Compound Research Comparison

Studies
(zm 241385)
Trials
(zm 241385)
Recent Studies (post-2010)
(zm 241385)
Studies
(ketoconazole)
Trials
(ketoconazole)
Recent Studies (post-2010) (ketoconazole)
40131241490120

Protein Interaction Comparison

ProteinTaxonomyzm 241385 (IC50)ketoconazole (IC50)
Bile salt export pumpHomo sapiens (human)3.4
Steroid 17-alpha-hydroxylase/17,20 lyaseHomo sapiens (human)1.175
Epoxide hydrolase 1 Homo sapiens (human)0.04
ATP-dependent translocase ABCB1Homo sapiens (human)1.058
Cytochrome P450 3A4Homo sapiens (human)0.2303
Cytochrome P450 2D6Homo sapiens (human)2.774
AromataseHomo sapiens (human)1.3026
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.4519
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.1272
Cytochrome P450 3A5Homo sapiens (human)0.2535
Bifunctional epoxide hydrolase 2Homo sapiens (human)0.04
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialHomo sapiens (human)0.3
Sterol 14-alpha demethylaseTrypanosoma cruzi strain CL Brener0.014

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Azuaje, J; Brea, J; Caamaño, O; García-Mera, X; Gutiérrez-de-Terán, H; Jespers, W; Loza, MI; Majellaro, M; Mallo-Abreu, A; Prieto-Díaz, R; Sotelo, E; Velando, C1

Other Studies

1 other study(ies) available for zm 241385 and ketoconazole

ArticleYear
Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A
    Journal of medicinal chemistry, 2020, 07-23, Volume: 63, Issue:14

    Topics: Adenosine A2 Receptor Antagonists; Animals; Cell Line, Tumor; CHO Cells; Cricetulus; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Humans; Imidazoles; Molecular Docking Simulation; Molecular Structure; Pyrimidines; Receptor, Adenosine A2B; Stereoisomerism; Structure-Activity Relationship

2020