zm 241385 has been researched along with kainic acid in 6 studies
| Studies (zm 241385) | Trials (zm 241385) | Recent Studies (post-2010) (zm 241385) | Studies (kainic acid) | Trials (kainic acid) | Recent Studies (post-2010) (kainic acid) |
|---|---|---|---|---|---|
| 401 | 3 | 124 | 9,540 | 3 | 1,775 |
| Protein | Taxonomy | zm 241385 (IC50) | kainic acid (IC50) |
|---|---|---|---|
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 4.2857 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 1 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.0126 | |
| Glutamate receptor ionotropic, kainate 2 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 3 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 4 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Homo sapiens (human) | 0.077 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.0126 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO | 1 |
| Jones, PA; Smith, RA; Stone, TW | 2 |
| Nikbakht, MR; Stone, TW | 1 |
| Galluzzo, M; Grieco, R; Pèzzola, A; Pintor, A; Popoli, P; Reggio, R | 1 |
| Hamilton, JB; Lancaster, DM; Patel, N; Pietersen, AN; Vreugdenhil, M | 1 |
6 other study(ies) available for zm 241385 and kainic acid
| Article | Year |
|---|---|
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles | 2005 |
Protection against kainate-induced excitotoxicity by adenosine A2A receptor agonists and antagonists.
Topics: Adenosine; Animals; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Triazines; Triazoles; Xanthines | 1998 |
Protection against hippocampal kainate excitotoxicity by intracerebral administration of an adenosine A2A receptor antagonist.
Topics: Adenosine; Adrenergic alpha-2 Receptor Antagonists; Animals; Antihypertensive Agents; Brain Chemistry; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neurotoxins; Phenethylamines; Rats; Rats, Wistar; Triazines; Triazoles | 1998 |
Suppression of presynaptic responses to adenosine by activation of NMDA receptors.
Topics: Action Potentials; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Baclofen; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Agonists; Glycine; Hippocampus; In Vitro Techniques; Kainic Acid; Long-Term Potentiation; Male; N-Methylaspartate; Phenethylamines; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A2A; Receptors, N-Methyl-D-Aspartate; Time Factors; Triazines; Triazoles | 2001 |
Adenosine A 2A receptor antagonists prevent the increase in striatal glutamate levels induced by glutamate uptake inhibitors.
Topics: Adenosine A2 Receptor Antagonists; Animals; Corpus Striatum; Dicarboxylic Acids; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glutamic Acid; Kainic Acid; Male; Microdialysis; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Pyrimidines; Pyrrolidines; Rats; Rats, Wistar; Receptor, Adenosine A2A; Triazines; Triazoles | 2004 |
Modulation of gamma oscillations by endogenous adenosine through A1 and A2A receptors in the mouse hippocampus.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Analysis of Variance; Animals; Biological Clocks; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Fourier Analysis; Hippocampus; Hypoxia; In Vitro Techniques; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Thioinosine; Time Factors; Triazines; Triazoles | 2009 |