Page last updated: 2024-09-03

zm 189154 and anastrozole

zm 189154 has been researched along with anastrozole in 2 studies

*Anastrozole: A nitrile and triazole derivative that acts as a selective nonsteroidal aromatase inhibitor. It is used in the treatment of ESTROGEN NUCLEAR RECEPTOR-positive breast cancer in postmenopausal women. [MeSH]

Compound Research Comparison

Studies (zm 189154)	Trials (zm 189154)	Recent Studies (post-2010) (zm 189154)	Studies (anastrozole)	Trials (anastrozole)	Recent Studies (post-2010) (anastrozole)
10	0	1	1,568	354	686

Protein Interaction Comparison

Protein	Taxonomy	anastrozole (IC50)
Aromatase	Homo sapiens (human)	0.1443
Cytochrome P450 2C9	Homo sapiens (human)	0.0036
Amine oxidase [flavin-containing] A	Rattus norvegicus (Norway rat)	0.0015
UDP-glucuronosyltransferase 1A4	Homo sapiens (human)	4.72

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ashby, J; Joiner, R; Odum, J; Tinwell, H; Van Miller, J	1
Ashby, J; Deghenghi, R; Odum, J; Owens, W	1

Other Studies

2 other study(ies) available for zm 189154 and anastrozole

Article	Year
The uterotrophic activity of nonylphenol in the rat is not mediated by aromatase enzyme induction. Toxicology letters, 2001, Jan-03, Volume: 118, Issue:3 Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Enzyme Induction; Enzyme Inhibitors; Female; Nitriles; Organ Size; Phenols; Rats; Rats, Wistar; Receptors, Estrogen; Tetrahydronaphthalenes; Triazoles; Uterus	2001
Concept evaluation: an assay for receptor-mediated and biochemical antiestrogens using pubertal rats. Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:3 Topics: Administration, Oral; Anastrozole; Animals; Biological Assay; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Injections, Subcutaneous; Nitriles; Oligopeptides; Organ Size; Rats; Rats, Wistar; Sexual Maturation; Tetrahydronaphthalenes; Triazoles; Uterus; Vagina	2002

Article

Year

The uterotrophic activity of nonylphenol in the rat is not mediated by aromatase enzyme induction.

Toxicology letters, 2001, Jan-03, Volume: 118, Issue:3

Topics: Anastrozole; Animals; Aromatase; Aromatase Inhibitors; Enzyme Induction; Enzyme Inhibitors; Female; Nitriles; Organ Size; Phenols; Rats; Rats, Wistar; Receptors, Estrogen; Tetrahydronaphthalenes; Triazoles; Uterus

2001

Concept evaluation: an assay for receptor-mediated and biochemical antiestrogens using pubertal rats.

Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:3

Topics: Administration, Oral; Anastrozole; Animals; Biological Assay; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Injections, Subcutaneous; Nitriles; Oligopeptides; Organ Size; Rats; Rats, Wistar; Sexual Maturation; Tetrahydronaphthalenes; Triazoles; Uterus; Vagina

2002