zk 93423 has been researched along with methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate in 6 studies
| Studies (zk 93423) | Trials (zk 93423) | Recent Studies (post-2010) (zk 93423) | Studies (methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate) | Trials (methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate) | Recent Studies (post-2010) (methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate) |
|---|---|---|---|---|---|
| 30 | 0 | 2 | 218 | 0 | 18 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P | 1 |
| Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S | 1 |
| Atsoggiu, T; Biggio, G; Concas, A; Serra, M | 1 |
| Jensen, LH; Petersen, EN | 1 |
| Little, HJ; Nutt, DJ; Taylor, SC | 1 |
| Kehr, W; Schmiechen, R; Schneider, HH; Stephens, DN | 1 |
6 other study(ies) available for zk 93423 and methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate
| Article | Year |
|---|---|
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship | 1998 |
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship | 2000 |
Foot-shock stress and anxiogenic beta-carbolines increase t-[35S]butylbicyclophosphorothionate binding in the rat cerebral cortex, an effect opposite to anxiolytics and gamma-aminobutyric acid mimetics.
Topics: Animals; Anti-Anxiety Agents; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebral Cortex; Convulsants; Diazepam; Electroshock; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Male; Muscimol; Rats; Rats, Inbred Strains; Receptors, GABA-A; Stress, Physiological | 1988 |
Chronic treatment with lorazepam and FG 7142 may change the effects of benzodiazepine receptor agonists, antagonists and inverse agonists by different mechanisms.
Topics: Animals; Carbolines; Drug Interactions; Drug Tolerance; Female; Flumazenil; Lorazepam; Mice; Pentylenetetrazole; Receptors, GABA-A | 1987 |
Selective changes in the in vivo effects of benzodiazepine receptor ligands after chemical kindling with FG 7142.
Topics: Animals; Benzodiazepines; Body Temperature; Carbolines; Flurazepam; Kindling, Neurologic; Mice; Pyrazoles; Receptors, GABA-A; Seizures | 1987 |
Beta-carbolines with agonistic and inverse agonistic properties at benzodiazepine receptors of the rat.
Topics: Animals; Arousal; Brain; Carbolines; Chlordiazepoxide; Conditioning, Operant; Cues; Indoles; Male; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Synaptic Transmission | 1984 |