zk 93423 has been researched along with beta-carboline-3-carboxylic acid ethyl ester in 3 studies
| Studies (zk 93423) | Trials (zk 93423) | Recent Studies (post-2010) (zk 93423) | Studies (beta-carboline-3-carboxylic acid ethyl ester) | Trials (beta-carboline-3-carboxylic acid ethyl ester) | Recent Studies (post-2010) (beta-carboline-3-carboxylic acid ethyl ester) |
|---|---|---|---|---|---|
| 30 | 0 | 2 | 240 | 0 | 9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fryer, RI; Gu, ZQ; Kamath, PG; Langer, T; Skolnick, P; Wang, CG | 1 |
| Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P | 1 |
| Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S | 1 |
3 other study(ies) available for zk 93423 and beta-carboline-3-carboxylic acid ethyl ester
| Article | Year |
|---|---|
Computer-aided molecular modeling, synthesis, and biological evaluation of 8-(benzyloxy)-2-phenylpyrazolo[4,3-c]quinoline as a novel benzodiazepine receptor agonist ligand.
Topics: Animals; Computer Simulation; Evaluation Studies as Topic; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Ligands; Models, Chemical; Molecular Conformation; Monte Carlo Method; Pyrazoles; Quinolones; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thermodynamics | 1995 |
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship | 1998 |
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship | 2000 |