Page last updated: 2024-09-03

zk 93423 and 3-propoxy-beta-carboline

zk 93423 has been researched along with 3-propoxy-beta-carboline in 2 studies

Compound Research Comparison

Studies
(zk 93423)
Trials
(zk 93423)
Recent Studies (post-2010)
(zk 93423)
Studies
(3-propoxy-beta-carboline)
Trials
(3-propoxy-beta-carboline)
Recent Studies (post-2010) (3-propoxy-beta-carboline)
30021804

Protein Interaction Comparison

ProteinTaxonomyzk 93423 (IC50)3-propoxy-beta-carboline (IC50)
Gamma-aminobutyric acid receptor subunit piHomo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit deltaHomo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit alpha-1Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.011
Translocator proteinRattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit beta-1Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit gamma-2Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit beta-3Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit alpha-5Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit alpha-3Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit alpha-2Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit beta-2Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit alpha-4Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit epsilonHomo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit alpha-6Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit gamma-1Homo sapiens (human)0.011
GABA theta subunitRattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit gamma-3Homo sapiens (human)0.011
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.011
Gamma-aminobutyric acid receptor subunit thetaHomo sapiens (human)0.011

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cook, JM; Cox, ED; Diaz-Arauzo, H; Harris, B; Huang, Q; Ma, C; McKernan, R; Reddy, MS; Skolnick, P1
Cook, JM; Dayer, CA; He, X; Huang, Q; Liu, R; Ma, C; McKernan, R; Wenger, GR; Yu, S1

Other Studies

2 other study(ies) available for zk 93423 and 3-propoxy-beta-carboline

ArticleYear
Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423)
    Journal of medicinal chemistry, 1998, Jul-02, Volume: 41, Issue:14

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Binding, Competitive; Carbolines; Cell Line; Cerebral Cortex; Drug Design; GABA Agonists; Humans; Male; Mice; Muscle Relaxation; Rats; Receptors, GABA-A; Recombinant Proteins; Seizures; Structure-Activity Relationship

1998
Pharmacophore/receptor models for GABA(A)/BzR subtypes (alpha1beta3gamma2, alpha5beta3gamma2, and alpha6beta3gamma2) via a comprehensive ligand-mapping approach.
    Journal of medicinal chemistry, 2000, Jan-13, Volume: 43, Issue:1

    Topics: Animals; Benzodiazepines; Carbolines; Cell Line; Columbidae; Conditioning, Operant; Crystallography, X-Ray; Humans; Indoles; Ligands; Male; Models, Molecular; Pyrimidines; Quinolones; Radioligand Assay; Receptors, GABA-A; Saimiri; Stereoisomerism; Structure-Activity Relationship

2000