Page last updated: 2024-09-03

zk 91587 and mifepristone

zk 91587 has been researched along with mifepristone in 4 studies

Compound Research Comparison

Studies
(zk 91587)
Trials
(zk 91587)
Recent Studies (post-2010)
(zk 91587)
Studies
(mifepristone)
Trials
(mifepristone)
Recent Studies (post-2010) (mifepristone)
23006,5365951,758

Protein Interaction Comparison

ProteinTaxonomyzk 91587 (IC50)mifepristone (IC50)
Glucocorticoid receptor Canis lupus familiaris (dog)0.0264
Bile salt export pumpHomo sapiens (human)2.02
Estrogen receptorHomo sapiens (human)4.311
Glucocorticoid receptorHomo sapiens (human)0.0249
Prostaglandin G/H synthase 1Ovis aries (sheep)0.0003
Progesterone receptorHomo sapiens (human)0.1347
Glucocorticoid receptorRattus norvegicus (Norway rat)0.774
Glucocorticoid receptorMus musculus (house mouse)0.0022
Glycine receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0022
Mineralocorticoid receptor Homo sapiens (human)2.0938
Cytochrome P450 3A4Homo sapiens (human)9.5
Coagulation factor VIIHomo sapiens (human)0.0003
Androgen receptorHomo sapiens (human)0.2988
Cytochrome P450 2C8Homo sapiens (human)1.5
Cytochrome P450 2C9 Homo sapiens (human)4.9
Steroid 17-alpha-hydroxylase/17,20 lyase Rattus norvegicus (Norway rat)0.0016
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)0.555
Tissue factorHomo sapiens (human)0.0003
Androgen receptorRattus norvegicus (Norway rat)0.0083
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0014
Glycine receptor subunit betaRattus norvegicus (Norway rat)0.0022
Glycine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0022
Prostaglandin G/H synthase 1Homo sapiens (human)0.0078
Glycine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0022
Substance-P receptorCavia porcellus (domestic guinea pig)0.0015
Mu-type opioid receptorHomo sapiens (human)2.457
Estrogen receptor betaHomo sapiens (human)1.528
Glucocorticoid receptorSus scrofa (pig)0.0153

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cosen-Binker, L; de Kloet, ER; De Nicola, AF; Gonzalez, S; Grillo, CA; McEwen, BS; Vallee, SM1
Asano, Y; Ebata, S; Kawakami, K; Muto, S; Nemoto, J1
Grafte-Faure, S; Leveque, C; Norris, V; Soria, C; Vannier, JP; Vasse, M1
Bussolino, D; Calfa, G; Molina, VA1

Other Studies

4 other study(ies) available for zk 91587 and mifepristone

ArticleYear
Further studies in deoxycorticosterone acetate treated rats: brain content of mineralocorticoid and glucocorticoid receptors and effect of steroid antagonists on salt intake.
    Neuroendocrinology, 1995, Volume: 61, Issue:2

    Topics: Amygdala; Animals; Appetite; Brain; Desoxycorticosterone; Hippocampus; Hypothalamus; Male; Mifepristone; Mineralocorticoid Receptor Antagonists; Ornithine Decarboxylase; Rats; Rats, Sprague-Dawley; Receptors, Glucocorticoid; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Spironolactone

1995
Corticosterone and 11-dehydrocorticosterone stimulate Na,K-ATPase gene expression in vascular smooth muscle cells.
    Kidney international, 1998, Volume: 54, Issue:2

    Topics: Animals; Aorta; Cells, Cultured; Corticosterone; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Male; Mifepristone; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium-Potassium-Exchanging ATPase; Spironolactone

1998
Effects of glucocorticoids and mineralocorticoids on proliferation and maturation of human peripheral blood stem cells.
    American journal of hematology, 1999, Volume: 62, Issue:2

    Topics: Adult; Aldosterone; Cells, Cultured; Colony-Forming Units Assay; Desoxycorticosterone; Erythropoietin; Glucocorticoids; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Interleukin-3; Mifepristone; Mineralocorticoids; Recombinant Proteins; Spironolactone; Triamcinolone Acetonide

1999
Involvement of the lateral septum and the ventral Hippocampus in the emotional sequelae induced by social defeat: role of glucocorticoid receptors.
    Behavioural brain research, 2007, Jul-19, Volume: 181, Issue:1

    Topics: Aggression; Analysis of Variance; Anesthetics, Local; Animals; Behavior, Animal; Dominance-Subordination; Emotions; Hippocampus; Hormone Antagonists; Lidocaine; Male; Maze Learning; Mifepristone; Oncogene Proteins v-fos; Rats; Rats, Wistar; Reaction Time; Receptors, Glucocorticoid; Septal Nuclei; Spironolactone; Stress, Psychological

2007