Page last updated: 2024-08-22

zirconium and deferoxamine

zirconium has been researched along with deferoxamine in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.43)18.7374
1990's3 (4.29)18.2507
2000's2 (2.86)29.6817
2010's44 (62.86)24.3611
2020's20 (28.57)2.80

Authors

AuthorsStudies
Haisma, HJ; Herscheid, JD; Meijs, WE; Pinedo, HM1
Brown, DJ; Dawborn, JK; Ham, KN; Johnson, CI; Nelson, S; Xipell, JM1
Haisma, HJ; Herscheid, JD; Klok, RP; Meijs, WE; Pinedo, HM; Van den Oever, K; Van der Schors, R; Wijbrandts, R1
Haisma, HJ; Herscheid, JD; Kievit, E; Klok, RP; Meijs, WE; Pinedo, HM; van Gog, FB1
Igarashi, S; Kubota, T; Takagai, Y; Takahashi, A; Yamaguchi, H1
Holland, JP; Lewis, JS; Sheh, Y1
Budde, M; Jurek, P; Kiefer, GE; Perk, LR; van Dongen, GA; Visser, GW; Vosjan, MJ2
Caldas-Lopes, E; Chiosis, G; Divilov, V; Holland, JP; Lewis, JS; Longo, VA; Taldone, T; Zatorska, D1
Grimm, J; Holland, JP; Lewis, JS; Ruggiero, A1
Holland, JP; Lewis, JS; May, C; McDevitt, MR; Ruggiero, A; Scheinberg, DA; Sprinkle, SR; Villa, CH1
Gebhardt, P; Grosse-Gehling, P; Irmler, I; Kamradt, T; Khalid, M; Opfermann, T; Preusche, S; Saluz, HP; Steinbach, J; Walther, M; Würbach, L1
Carlin, S; Divilov, V; Heneweer, C; Holland, JP; Lewis, JS1
Barnhart, TE; Cai, W; Engle, JW; Hong, H; Leigh, BR; Liu, G; Nickles, RJ; Severin, GW; Yang, Y; Zhang, Y1
Gambhir, SS; Habte, F; Natarajan, A1
Evans, MJ; Holland, JP; Lewis, JS; Rice, SL; Sawyers, CL; Wongvipat, J1
Brechbiel, MW; Deschamps, JR; Guérard, F; Lee, YS; Szajek, LP; Tripier, R1
Aggeler, R; Agnew, BJ; Chen, A; Davis, CB; Kang, HC; Lewis, JS; Zeglis, BM1
Fischer, G; Schirrmacher, R; Seibold, U; Wängler, B; Wängler, C1
Brechbiel, MW; Guérard, F; Lee, YS1
Bhadrasetty, V; Chaudhary, A; Choyke, P; Coble, V; Elbuluk, O; Griffiths, GL; Histed, S; Jagoda, EM; Kuo, F; Lane, K; Paik, CH; St Croix, B; Szajek, LP; Szot, C; Vasalatiy, O; Williams, MR; Wong, K; Wu, H; Xu, B1
Bauman, A; Blacque, O; Fischer, CA; Gasser, G; Häussinger, D; Mari, C; Mindt, TL; Patra, M1
Berry, DJ; Blower, PJ; Cooper, MS; Hider, RC; Ma, MT; Ma, Y; Meszaros, LK; Paterson, BM1
Ferrara, KW; Ingham, ES; Mahakian, LM; Meares, CF; Qin, S; Seo, JW; Tam, S1
Lewis, JS; Zeglis, BM1
Bauman, A; Fischer, CA; Mindt, TL; Valverde, IE; Vomstein, S1
Abdel-Atti, D; Houghton, JL; Lewis, JS; Sawada, R; Scholz, WW; Zeglis, BM1
Del Pozzo, L; Holland, JP; Illert, AL; Klingeberg, C; Maecke, HR; Meyer, PT; Rylova, SN; Tönnesmann, R1
Burton-Pye, BP; Cicek, HT; Deri, MA; Francesconi, LC; Hu, C; Kozlowski, P; Lewis, JS; Ponnala, S1
Escuin-Ordinas, H; McCracken, MN; Mok, S; Ribas, A; Salazar, FB; Tavaré, R; Witte, ON; Wu, AM; Zettlitz, KA1
Balatoni, JA; González-Lepera, C; Lin, M; Mukhopadhyay, U; Waligorski, GJ1
Abdel-Atti, D; Aggeler, R; Agnew, BJ; Houghton, JL; Lewis, JS; Sawada, R; Scholz, WW; Zeglis, BM1
Boros, E; Caravan, P; Carlson, JC; Meimetis, LG; Ran, C; Weissleder, R1
Augustyns, K; De Vijlder, T; Dedeurwaerdere, S; Fissers, J; Joossens, J; Mercken, M; Pemberton, DJ; Staelens, S; Stroobants, S; Van Broeck, B; Van Der Veken, P; Waldron, AM; Wyffels, L1
Burvenich, IJ; Gan, HK; Gong, S; Guo, N; Hasegawa, J; Kotsuma, M; Lee, FT; Lee, ST; O'Keefe, GJ; Parakh, S; Rigopoulos, A; Scott, AM; Senaldi, G; Tochon-Danguy, H1
Boutin, H; Brown, G; Ellis, B; Fairclough, M; Jones, AK; Locatelli, P; McMahon, A; Prenant, C1
Glassner, M; Hoogenboom, R; Monnery, BD; Staelens, S; Stroobants, S; Verbrugghen, T; Wyffels, L1
Cullinane, C; Donnelly, PS; Hicks, RJ; Roselt, P; Rudd, SE1
Adamzek, K; Bolijn, M; Haselberg, R; Houthoff, HJ; Merkul, E; Montserrat, V; Muns, JA; Sijbrandi, NJ; Somsen, GW; Steverink, PJ; van Dongen, GA; Waalboer, DC1
Bénard, F; Colpo, N; Dias, GM; Lin, KS; Rousseau, J; Zhang, C; Zhang, Z1
Blower, PJ; Li, N; Pham, TT; Yan, R; Yu, Z1
Boerman, O; Denat, F; Goncalves, V; Heskamp, S; Raavé, R; Rijpkema, M1
Andersson, KG; Decristoforo, C; Garousi, J; Löfblom, J; Mitran, B; Orlova, A; Oroujeni, M; Summer, D; Tolmachev, V; Vorobyeva, A1
Codd, R; Gotsbacher, MP; Richardson-Sanchez, T; Telfer, TJ1
Beckford Vera, DR; Bixby, LM; Dunn, SS; Glatt, DM; Kim, WY; Parrott, MC; Saito, R; Serody, JS; Smith, CC; Vincent, BG1
Bhatt, NB; Pandya, DN; Wadas, TJ1
Al-Dulaymi, M; Badea, I; Fonge, H; Hajdu, I; Makhlouf, A; Michel, D; Solomon, VR; Wasan, KM1
Ahn, SH; Alford, VM; Boros, E; Laughlin, ST; Preston, AN; Thach, D; Vaughn, BA1
Adumeau, P; Fung, K; Rodriguez, C; Sharma, SK; Vivier, D; Zeglis, BM1
Gumienna-Kontecka, E; Toporivska, Y1
Cho, EH; Choi, K; Chung, J; Chung, JH; Ju, JM; Kim, H; Kim, SY; Lee, SH; Lee, SJ; Oh, SJ; Ryu, JS; Sheen, JH; Soh, H1
Fay, R; Holland, JP; Klingler, S1
Holland, JP1
Aulsebrook, ML; Brandt, M; Cowell, J; Gasser, G; Mindt, TL1
Boffi, A; Bonamore, A; Braniewska, A; Cerutti, G; Clarkson, R; Dabkowski, AM; Kiraga, Ł; Król, M; Kucharzewska, P; Montemiglio, LC; Paisey, SJ; Rygiel, TP; Sas, Z; Savino, C; Seaton, G; Strzemecki, D; Taciak, B; Turnham, D1
Cullinane, C; Donnelly, PS; Haskali, MB; Hicks, RJ; Noor, A; Roselt, PD; Rudd, SE; Van Zuylekom, JK; Waldeck, K; Wheatcroft, MP; Yan, E1
Lewis, JS; Price, EW; Raheem, SJ; Salih, AK; Sarbisheh, EK1
Beaino, W; Bolijn, MJ; Brown, K; Chomet, M; Cowell, J; Gasser, G; Gill, H; Marik, J; Mindt, TL; Poot, AJ; Schreurs, M; van Dongen, GAMS; Verlaan, M; Vugts, DJ; Williams, S; Windhorst, AD1
Cullinane, C; Donnelly, PS; Haskali, MB; Hicks, RJ; Noor, A; Roselt, PD; Rudd, SE; Van Zuylekom, JK; Wheatcroft, M; Yan, E1
Earley, DF; Fay, R; Guillou, A; Holland, JP; Klingler, S; Nisli, E; Nüesch, LJ1
Bellotti, D; Remelli, M1
Carlsten, M; Friberger, I; Goos, JACM; Han, J; Harris, RA; Holmin, S; Jussing, E; Kaipe, H; Lambert, M; Samén, E; Siikanen, J; Tran, TA1
Fortin, MA; Lagueux, J; Laprise-Pelletier, M; Lemay, S; Omar, MM; Tuduri, L1
Ida, H; Imura, R; Ishioka, NS; Sasaki, I; Watanabe, S1
Bianchi, A; Boscaro, F; Savastano, M1
Babazada, H; Chang, B; Edwards, KJ; Farwell, MD; Lohith, K; Park, DH; Sellmyer, MA1
Bubenshchikov, V; Larenkov, A; Makichyan, A1
Bjørnsdottir, I; Boswinkel, M; Fernandes, EFA; Glendorf, T; Gustafsson, MBF; Heskamp, S; Raavé, R; Rodríguez, D; Wilbs, J1
Frangioni, JV; Maison, W; Münzmay, M; Outzen, L1
Aprile, FA; Ge, Y; Long, NJ; Ma, MT; Pham, TT; Yue, TTC1

Reviews

5 review(s) available for zirconium and deferoxamine

ArticleYear
(89)Zr, a radiometal nuclide with high potential for molecular imaging with PET: chemistry, applications and remaining challenges.
    Molecules (Basel, Switzerland), 2013, Jun-03, Volume: 18, Issue:6

    Topics: Deferoxamine; Isotope Labeling; Molecular Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Zirconium

2013
    Bioconjugate chemistry, 2017, 09-20, Volume: 28, Issue:9

    Topics: Animals; Chelating Agents; Deferoxamine; Drug Delivery Systems; Drug Discovery; Humans; Immunoconjugates; Neoplasms; Positron-Emission Tomography; Radiochemistry; Radioisotopes; Zirconium

2017
Advances in the Chemical Biology of Desferrioxamine B.
    ACS chemical biology, 2018, 01-19, Volume: 13, Issue:1

    Topics: Anti-Bacterial Agents; Biochemistry; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Deferoxamine; Fluorescent Dyes; Humans; Hydrolysis; Iron Chelating Agents; Positron-Emission Tomography; Siderophores; Zirconium

2018
Recent Advances in Zirconium-89 Chelator Development.
    Molecules (Basel, Switzerland), 2018, Mar-12, Volume: 23, Issue:3

    Topics: Animals; Chelating Agents; Deferoxamine; Humans; Molecular Structure; Positron-Emission Tomography; Radioisotopes; Zirconium

2018
Deferoxamine B: A Natural, Excellent and Versatile Metal Chelator.
    Molecules (Basel, Switzerland), 2021, May-28, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Chelating Agents; Chemistry, Pharmaceutical; COVID-19 Drug Treatment; Deferoxamine; Electrochemistry; Electrolytes; Humans; Hydrogen-Ion Concentration; Ions; Iron; Iron Chelating Agents; Iron Overload; Kinetics; Ligands; Metals; Neoplasms; Potentiometry; SARS-CoV-2; Temperature; Zirconium

2021

Other Studies

65 other study(ies) available for zirconium and deferoxamine

ArticleYear
Evaluation of desferal as a bifunctional chelating agent for labeling antibodies with Zr-89.
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1992, Volume: 43, Issue:12

    Topics: Antibodies; Chelating Agents; Deferoxamine; Evaluation Studies as Topic; Isotope Labeling; Radioisotopes; Zirconium

1992
Dialysis osteomalacia: a possible role for zirconium as well as aluminium.
    Pathology, 1985, Volume: 17, Issue:3

    Topics: Chronic Kidney Disease-Mineral and Bone Disorder; Deferoxamine; Glomerulonephritis; Humans; Osteomalacia; Zirconium

1985
A facile method for the labeling of proteins with zirconium isotopes.
    Nuclear medicine and biology, 1996, Volume: 23, Issue:4

    Topics: Animals; Cattle; Chelating Agents; Deferoxamine; Drug Stability; Female; Isotope Labeling; Mice; Mice, Inbred BALB C; Protein Binding; Radioisotopes; Serum Albumin, Bovine; Tissue Distribution; Zirconium

1996
Zirconium-labeled monoclonal antibodies and their distribution in tumor-bearing nude mice.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Deferoxamine; Immunoconjugates; Isotope Labeling; Mice; Mice, Nude; Neoplasms; Tissue Distribution; Tomography, Emission-Computed; Transplantation, Heterologous; Tumor Cells, Cultured; Zirconium

1997
Adsorption behaviors of high-valence metal ions on desferrioxamine B immobilization nylon 6,6 chelate fiber under highly acidic conditions.
    Journal of colloid and interface science, 2007, Sep-01, Volume: 313, Issue:1

    Topics: Adsorption; Biochemistry; Caprolactam; Deferoxamine; Hafnium; Hydrogen-Ion Concentration; Ions; Metals; Models, Chemical; Polymers; Siderophores; Solvents; Surface Properties; Zirconium

2007
Standardized methods for the production of high specific-activity zirconium-89.
    Nuclear medicine and biology, 2009, Volume: 36, Issue:7

    Topics: Animals; Benchmarking; Chelating Agents; Cyclotrons; Deferoxamine; Humans; Hydroxamic Acids; Ligands; Male; Mice; Positron-Emission Tomography; Radioisotopes; Reproducibility of Results; Zirconium

2009
p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging.
    European journal of nuclear medicine and molecular imaging, 2010, Volume: 37, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Line, Tumor; Chelating Agents; Deferoxamine; Female; Humans; Isothiocyanates; Isotope Labeling; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Positron-Emission Tomography; Radioimmunodetection; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Zirconium

2010
Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/neu expression in mice using Zr-DFO-trastuzumab.
    PloS one, 2010, Jan-25, Volume: 5, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzodioxoles; Cell Line, Tumor; Deferoxamine; Female; Genes, erbB-2; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, Nude; Purines; Tissue Distribution; Trastuzumab; Zirconium

2010
Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine.
    Nature protocols, 2010, Volume: 5, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Deferoxamine; Head and Neck Neoplasms; Humans; Isothiocyanates; Mice; Mice, Nude; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Transplantation, Heterologous; Zirconium

2010
Cerenkov luminescence imaging of medical isotopes.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:7

    Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Beta Particles; Deferoxamine; Diagnostic Imaging; Drug Evaluation, Preclinical; Electrons; Female; Humans; Luminescence; Male; Mice; Neoplasm Transplantation; Neoplasms; Phantoms, Imaging; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Zirconium

2010
Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes.
    International journal of nanomedicine, 2010, Oct-05, Volume: 5

    Topics: Actinium; Adenocarcinoma; Animals; Cell Line, Tumor; Colonic Neoplasms; Deferoxamine; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice; Mice, Nude; Nanomedicine; Nanotubes, Carbon; Neovascularization, Pathologic; Positron-Emission Tomography; Radioimmunodetection; Radioimmunotherapy; Radioisotopes; Radiopharmaceuticals; Xenograft Model Antitumor Assays; Zirconium

2010
Implementation of 89Zr production and in vivo imaging of B-cells in mice with 89Zr-labeled anti-B-cell antibodies by small animal PET/CT.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2011, Volume: 69, Issue:6

    Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; B-Lymphocytes; Chelating Agents; Deferoxamine; Indoles; Isotope Labeling; Lymph Nodes; Mice; Mice, Inbred DBA; Mice, Nude; Positron-Emission Tomography; Quinoxalines; Radiography; Radioimmunodetection; Radioisotopes; Spectrometry, Gamma; Spleen; Tissue Distribution; Zirconium

2011
Magnitude of enhanced permeability and retention effect in tumors with different phenotypes: 89Zr-albumin as a model system.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2011, Volume: 52, Issue:4

    Topics: Animals; Autoradiography; Deferoxamine; Drug Stability; Humans; Image Processing, Computer-Assisted; Iron Chelating Agents; Male; Mice; Neoplasm Transplantation; Neoplasms; Permeability; Positron-Emission Tomography; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Serum Albumin; Tissue Distribution; Transplantation, Heterologous; Ultrasonography; Zirconium

2011
Positron emission tomography imaging of CD105 expression with 89Zr-Df-TRC105.
    European journal of nuclear medicine and molecular imaging, 2012, Volume: 39, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Cell Line, Tumor; Deferoxamine; Endoglin; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Mice; Positron-Emission Tomography; Radioisotopes; Receptors, Cell Surface; Zirconium

2012
Development of a novel long-lived immunoPET tracer for monitoring lymphoma therapy in a humanized transgenic mouse model.
    Bioconjugate chemistry, 2012, Jun-20, Volume: 23, Issue:6

    Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Cell Line, Tumor; Deferoxamine; Gene Expression; Humans; Immunoconjugates; Isothiocyanates; Lymphoma; Mice; Mice, Nude; Mice, Transgenic; Positron-Emission Tomography; Rituximab; Tissue Distribution; Zirconium

2012
Annotating MYC status with 89Zr-transferrin imaging.
    Nature medicine, 2012, Volume: 18, Issue:10

    Topics: Animals; Deferoxamine; Male; Mice; Mice, Transgenic; Positron-Emission Tomography; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Proto-Oncogene Proteins c-myc; Radioisotopes; Radiopharmaceuticals; Receptors, Transferrin; Transferrin; Transplantation, Heterologous; Zirconium

2012
Investigation of Zr(IV) and 89Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging.
    Chemical communications (Cambridge, England), 2013, Feb-01, Volume: 49, Issue:10

    Topics: Chelating Agents; Coordination Complexes; Crystallography, X-Ray; Deferoxamine; Hydroxamic Acids; Models, Molecular; Molecular Structure; Positron-Emission Tomography; Quantum Theory; Radioisotopes; Zirconium

2013
Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry.
    Bioconjugate chemistry, 2013, Jun-19, Volume: 24, Issue:6

    Topics: Animals; Antibodies; beta-Galactosidase; Binding Sites; Click Chemistry; Deferoxamine; Humans; Isotope Labeling; Male; Mice; Mice, Nude; Molecular Structure; Organometallic Compounds; Polysaccharides; Tumor Cells, Cultured; Zirconium

2013
Rational design, synthesis, and evaluation of tetrahydroxamic acid chelators for stable complexation of zirconium(IV).
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, May-05, Volume: 20, Issue:19

    Topics: Chelating Agents; Coordination Complexes; Crystallography, X-Ray; Deferoxamine; Edetic Acid; Ferric Compounds; Hydroxamic Acids; Kinetics; Positron-Emission Tomography; Radioisotopes; Zirconium

2014
Immuno-PET imaging of tumor endothelial marker 8 (TEM8).
    Molecular pharmaceutics, 2014, Nov-03, Volume: 11, Issue:11

    Topics: Animals; Antibodies, Monoclonal, Humanized; Blotting, Western; Deferoxamine; Female; Humans; Immunoprecipitation; Mice; Mice, Nude; Microfilament Proteins; Molecular Imaging; Neoplasm Proteins; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Cell Surface; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zirconium

2014
An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes.
    Chemical communications (Cambridge, England), 2014, Oct-09, Volume: 50, Issue:78

    Topics: Cell Line, Tumor; Chelating Agents; Coordination Complexes; Crystallography, X-Ray; Deferoxamine; Humans; Molecular Conformation; Molecular Probes; Peptides; Radiopharmaceuticals; Zirconium

2014
Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B.
    Dalton transactions (Cambridge, England : 2003), 2015, Mar-21, Volume: 44, Issue:11

    Topics: Animals; Deferoxamine; Drug Stability; Female; Humans; Immunoconjugates; Isotope Labeling; Ligands; Male; Mice; Positron-Emission Tomography; Pyridines; Radioisotopes; Trastuzumab; Zirconium

2015
The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:2

    Topics: Animals; Chemistry, Pharmaceutical; Deferoxamine; Disease Models, Animal; Drug Stability; Humans; Isotope Labeling; Liposomes; Mammary Neoplasms, Experimental; Mice; Phosphatidylethanolamines; Polyethylene Glycols; Positron-Emission Tomography; Radioisotopes; Tissue Distribution; Zirconium

2015
The bioconjugation and radiosynthesis of 89Zr-DFO-labeled antibodies.
    Journal of visualized experiments : JoVE, 2015, Feb-12, Issue:96

    Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Deferoxamine; Heterografts; Humans; Immunoconjugates; Male; Mice; Mice, Nude; Positron-Emission Tomography; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Zirconium

2015
Development of 68Ga- and 89Zr-Labeled Exendin-4 as Potential Radiotracers for the Imaging of Insulinomas by PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:10

    Topics: Animals; Deferoxamine; Exenatide; Gallium Radioisotopes; Insulinoma; Isotope Labeling; Mice; Mice, Nude; Pancreatic Neoplasms; Peptides; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Venoms; Zirconium

2015
Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:3

    Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Cell Line, Tumor; Copper Radioisotopes; Deferoxamine; Heterocyclic Compounds, 1-Ring; Humans; Mice; Neoplasm Transplantation; Pancreatic Neoplasms; Positron-Emission Tomography; Radiation Dosage; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Zirconium

2016
Immuno-PET Imaging of CD30-Positive Lymphoma Using 89Zr-Desferrioxamine-Labeled CD30-Specific AC-10 Antibody.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cell Line, Tumor; Deferoxamine; Drug Stability; Female; Humans; Immunoconjugates; Ki-1 Antigen; Lymphoma; Mice; Positron-Emission Tomography; Radiochemistry; Radioisotopes; Tissue Distribution; Zirconium

2016
p-SCN-Bn-HOPO: A Superior Bifunctional Chelator for (89)Zr ImmunoPET.
    Bioconjugate chemistry, 2015, Dec-16, Volume: 26, Issue:12

    Topics: Animals; Breast; Breast Neoplasms; Cell Line, Tumor; Chelating Agents; Deferoxamine; Female; Humans; Immunoconjugates; Mice, Nude; Models, Molecular; Positron-Emission Tomography; Pyridones; Tissue Distribution; Trastuzumab; Zirconium

2015
An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.
    Cancer research, 2016, Jan-01, Volume: 76, Issue:1

    Topics: Animals; Antibodies, Bispecific; CD8 Antigens; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Deferoxamine; Disease Models, Animal; Humans; Immunoconjugates; Immunotherapy, Adoptive; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Zirconium

2016
Semi-automated production of ⁸⁹Zr-oxalate/⁸⁹Zr-chloride and the potential of ⁸⁹Zr-chloride in radiopharmaceutical compounding.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2016, Volume: 107

    Topics: Chemistry, Pharmaceutical; Chlorides; Cyclotrons; Deferoxamine; Humans; Immunoglobulin G; Isotope Labeling; Oxalates; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Solid Phase Extraction; Zirconium

2016
Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Dec-29, Volume: 112, Issue:52

    Topics: Animals; Antibodies, Monoclonal; CA-19-9 Antigen; Cell Line, Tumor; Deferoxamine; Disease Models, Animal; Female; Fluorescent Dyes; Humans; Immunoconjugates; Mice, Knockout; Mice, Nude; Microscopy, Fluorescence; Molecular Structure; Multimodal Imaging; Pancreatic Neoplasms; Positron-Emission Tomography; Radioisotopes; Reproducibility of Results; Sensitivity and Specificity; Spectroscopy, Near-Infrared; Tissue Distribution; Transplantation, Heterologous; Zirconium

2015
Bioorthogonal Fluorophore Linked DFO-Technology Enabling Facile Chelator Quantification and Multimodal Imaging of Antibodies.
    Bioconjugate chemistry, 2016, Jan-20, Volume: 27, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Boron Compounds; Chelating Agents; Deferoxamine; Female; Fluorescent Dyes; Humans; Mice, Nude; Multimodal Imaging; Positron-Emission Tomography; Radioisotopes; Receptor, ErbB-2; Tissue Distribution; Trastuzumab; Xenograft Model Antitumor Assays; Zirconium

2016
Synthesis and Evaluation of a Zr-89-Labeled Monoclonal Antibody for Immuno-PET Imaging of Amyloid-β Deposition in the Brain.
    Molecular imaging and biology, 2016, Volume: 18, Issue:4

    Topics: Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Autoradiography; Brain; Deferoxamine; Humans; Immunohistochemistry; Mice, Inbred C57BL; Mice, Transgenic; Positron-Emission Tomography; Staining and Labeling; Tissue Distribution; Zirconium

2016
Molecular Imaging and Quantitation of EphA2 Expression in Xenograft Models with 89Zr-DS-8895a.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:6

    Topics: Animals; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Transformation, Neoplastic; Deferoxamine; Female; Humans; Isothiocyanates; Mice; Pentetic Acid; Positron-Emission Tomography; Quality Control; Radioisotopes; Receptor, EphA2; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Zirconium

2016
A new technique for the radiolabelling of mixed leukocytes with zirconium-89 for inflammation imaging with positron emission tomography.
    Journal of labelled compounds & radiopharmaceuticals, 2016, 06-15, Volume: 59, Issue:7

    Topics: Chitosan; Copper Radioisotopes; Deferoxamine; Humans; Inflammation; Isotope Labeling; Leukocytes; Nanoparticles; Positron-Emission Tomography; Radioisotopes; Zirconium

2016
μPET imaging of the pharmacokinetic behavior of medium and high molar mass (89)Zr-labeled poly(2-ethyl-2-oxazoline) in comparison to poly(ethylene glycol).
    Journal of controlled release : official journal of the Controlled Release Society, 2016, 08-10, Volume: 235

    Topics: Animals; Deferoxamine; Isothiocyanates; Kidney; Liver; Male; Mice, Inbred C57BL; Molecular Weight; Myocardium; Polyamines; Polyethylene Glycols; Positron-Emission Tomography; Radioisotopes; Siderophores; Tissue Distribution; Zirconium

2016
A desferrioxamine B squaramide ester for the incorporation of zirconium-89 into antibodies.
    Chemical communications (Cambridge, England), 2016, Sep-29, Volume: 52, Issue:80

    Topics: Animals; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Cell Line, Tumor; Deferoxamine; Disease Models, Animal; Female; Humans; Isotope Labeling; Mice; Positron-Emission Tomography; Radioisotopes; Receptor, ErbB-2; Transplantation, Heterologous; Trastuzumab; Zirconium

2016
A Novel Platinum(II)-Based Bifunctional ADC Linker Benchmarked Using 89Zr-Desferal and Auristatin F-Conjugated Trastuzumab.
    Cancer research, 2017, 01-15, Volume: 77, Issue:2

    Topics: Aminobenzoates; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Deferoxamine; Drug Design; Humans; Immunoconjugates; Mice; Oligopeptides; Platinum Compounds; Radioactive Tracers; Stomach Neoplasms; Trastuzumab; Xenograft Model Antitumor Assays; Zirconium

2017
Design, synthesis and evaluation of novel bifunctional tetrahydroxamate chelators for PET imaging of
    Bioorganic & medicinal chemistry letters, 2017, 02-15, Volume: 27, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Bone and Bones; Chelating Agents; Contrast Media; Coordination Complexes; Deferoxamine; Drug Design; Hydroxamic Acids; Isotope Labeling; Mice; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Trastuzumab; Zirconium

2017
A generic
    International journal of nanomedicine, 2017, Volume: 12

    Topics: Animals; Deferoxamine; Drug Stability; Female; Folic Acid; Humans; Isotope Labeling; Liposomes; Mice; Mice, Nude; Nanoparticles; Positron-Emission Tomography; Quinolinic Acid; Radioisotopes; Radiopharmaceuticals; Rats; Tissue Distribution; Xenograft Model Antitumor Assays; Zirconium

2017
Cyclic versus Noncyclic Chelating Scaffold for
    Molecular pharmaceutics, 2018, 01-02, Volume: 15, Issue:1

    Topics: Animals; Autoradiography; Cell Line, Tumor; Chelating Agents; Chromatography, High Pressure Liquid; Deferoxamine; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Female; Ferric Compounds; Humans; Hydroxamic Acids; Mice; Mice, Inbred BALB C; Positron-Emission Tomography; Radioisotopes; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xenograft Model Antitumor Assays; Zirconium

2018
Immuno-PET imaging of tumor-infiltrating lymphocytes using zirconium-89 radiolabeled anti-CD3 antibody in immune-competent mice bearing syngeneic tumors.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Animals; Antibodies; Butylhydroxybutylnitrosamine; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Deferoxamine; Flow Cytometry; Lymphocytes, Tumor-Infiltrating; Mice, Inbred C57BL; Neoplasm Transplantation; Positron Emission Tomography Computed Tomography; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Urinary Bladder Neoplasms; Zirconium

2018
A
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Animals; Cell Survival; Deferoxamine; Gene Expression Regulation; Gene Transfer Techniques; Genetic Therapy; Imaging, Three-Dimensional; Lipids; Mice, Nude; Nanoparticles; Neoplasms; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Surface-Active Agents; Tissue Distribution; Zirconium

2018
Linear Desferrichrome-Linked Silicon-Rhodamine Antibody Conjugate Enables Targeted Multimodal Imaging of HER2 in Vitro and in Vivo.
    Molecular pharmaceutics, 2019, 03-04, Volume: 16, Issue:3

    Topics: Animals; Cell Line, Tumor; Chelating Agents; Deferoxamine; Female; Heterografts; Humans; Immunoconjugates; In Vitro Techniques; Isotope Labeling; Mice; Mice, Nude; Positron Emission Tomography Computed Tomography; Radioisotopes; Radiopharmaceuticals; Receptor, ErbB-2; Rhodamines; Silicon; Tissue Distribution; Trastuzumab; Zirconium

2019
The Impact of FcγRI Binding on Immuno-PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2019, Volume: 60, Issue:8

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Deferoxamine; Female; Glycosylation; Humans; Immunoconjugates; Immunoglobulin G; In Vitro Techniques; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Positron-Emission Tomography; Radiopharmaceuticals; Receptor, ErbB-2; Receptors, IgG; Recombinant Proteins; Surface Plasmon Resonance; Tissue Distribution; Trastuzumab; Zirconium

2019
The solution thermodynamic stability of desferrioxamine B (DFO) with Zr(IV).
    Journal of inorganic biochemistry, 2019, Volume: 198

    Topics: Calorimetry; Coordination Complexes; Deferoxamine; Ligands; Siderophores; Thermodynamics; Zirconium

2019
Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging.
    PloS one, 2020, Volume: 15, Issue:1

    Topics: Cell Proliferation; Cell Survival; Deferoxamine; Hematologic Neoplasms; Humans; Immunoconjugates; Isothiocyanates; Isotope Labeling; Jurkat Cells; Leukocytes, Mononuclear; Positron-Emission Tomography; Radioisotopes; Receptors, Antigen, T-Cell; Receptors, Chimeric Antigen; T-Lymphocytes; Tissue Distribution; Zirconium

2020
Light-Induced Radiosynthesis of
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2020, Volume: 61, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Azepines; Cell Line, Tumor; Chemistry Techniques, Synthetic; Deferoxamine; Half-Life; Humans; Light; Mice; Positron-Emission Tomography; Proto-Oncogene Proteins c-met; Radiochemistry; Radioisotopes; Tissue Distribution; Zirconium

2020
Predicting the Thermodynamic Stability of Zirconium Radiotracers.
    Inorganic chemistry, 2020, Feb-03, Volume: 59, Issue:3

    Topics: Chelating Agents; Coordination Complexes; Deferoxamine; Density Functional Theory; Ligands; Models, Molecular; Positron-Emission Tomography; Radioactive Tracers; Thermodynamics; Zirconium

2020
Radiolabelling of the octadentate chelators DFO* and oxoDFO* with zirconium-89 and gallium-68.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2020, Volume: 25, Issue:5

    Topics: Chelating Agents; Coordination Complexes; Deferoxamine; Gallium Radioisotopes; Molecular Structure; Radioisotopes; Radiopharmaceuticals; Zirconium

2020
Biodistribution PET/CT Study of Hemoglobin-DFO-
    International journal of molecular sciences, 2020, Jul-15, Volume: 21, Issue:14

    Topics: Animals; Cell Line, Tumor; Coordination Complexes; Deferoxamine; Drug Carriers; Drug Delivery Systems; Female; Hemoglobins; Humans; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Models, Molecular; Positron Emission Tomography Computed Tomography; Radioisotopes; Tissue Distribution; Zirconium

2020
Bivalent Inhibitors of Prostate-Specific Membrane Antigen Conjugated to Desferrioxamine B Squaramide Labeled with Zirconium-89 or Gallium-68 for Diagnostic Imaging of Prostate Cancer.
    Journal of medicinal chemistry, 2020, 09-10, Volume: 63, Issue:17

    Topics: Animals; Antigens, Surface; Cell Line, Tumor; Cell Transformation, Neoplastic; Deferoxamine; Enzyme Inhibitors; Gallium Radioisotopes; Glutamate Carboxypeptidase II; Humans; Isotope Labeling; Male; Mice; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Quinine; Radioisotopes; Tissue Distribution; Zirconium

2020
A High-Denticity Chelator Based on Desferrioxamine for Enhanced Coordination of Zirconium-89.
    Inorganic chemistry, 2020, Aug-17, Volume: 59, Issue:16

    Topics: Coordination Complexes; Deferoxamine; Density Functional Theory; Iron Chelating Agents; Zirconium

2020
Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinical
    European journal of nuclear medicine and molecular imaging, 2021, Volume: 48, Issue:3

    Topics: Animals; Cell Line, Tumor; Chelating Agents; Deferoxamine; Mice; Positron-Emission Tomography; Radioisotopes; Tissue Distribution; Zirconium

2021
Imaging Somatostatin Positive Tumors with Tyr
    Bioconjugate chemistry, 2021, 07-21, Volume: 32, Issue:7

    Topics: Animals; Deferoxamine; Gallium Radioisotopes; Mice; Octreotide; Quinine; Radioisotopes; Somatostatin; Zirconium

2021
The Influence of a Polyethylene Glycol Linker on the Metabolism and Pharmacokinetics of a
    Bioconjugate chemistry, 2021, 07-21, Volume: 32, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Chromatography, Liquid; Deferoxamine; Immunoconjugates; Mice; Mice, Nude; Polyethylene Glycols; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Zirconium

2021
Optimisation of the Synthesis and Cell Labelling Conditions for [
    Molecular imaging and biology, 2021, Volume: 23, Issue:6

    Topics: Animals; Cell Line, Tumor; Deferoxamine; Oxyquinoline; Positron-Emission Tomography; Radioisotopes; Rats; Tissue Distribution; Zirconium

2021
A diffusion cell adapted to nuclear imaging instruments for the measurement of molecular release and pharmacokinetics across membranes.
    Journal of controlled release : official journal of the Controlled Release Society, 2021, 09-10, Volume: 337

    Topics: Deferoxamine; Positron-Emission Tomography; Radioisotopes; Renal Dialysis; Tissue Distribution; Zirconium

2021
Re-Evaluations of Zr-DFO Complex Coordination Chemistry for the Estimation of Radiochemical Yields and Chelator-to-Antibody Ratios of
    Molecules (Basel, Switzerland), 2021, Aug-17, Volume: 26, Issue:16

    Topics: Antibodies, Monoclonal; Cell Line, Tumor; Chelating Agents; Deferoxamine; Humans; Isotope Labeling; Positron-Emission Tomography; Radiochemistry; Radioisotopes; Zirconium

2021
Metal Coordination Properties of a Chromophoric Desferrioxamine (DFO) Derivative: Insight on the Coordination Stoichiometry and Thermodynamic Stability of Zr
    Molecules (Basel, Switzerland), 2021, Dec-29, Volume: 27, Issue:1

    Topics: Chelating Agents; Chemical Phenomena; Coordination Complexes; Deferoxamine; Models, Theoretical; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Spectrum Analysis; Thermodynamics; Zirconium

2021
Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation.
    Cancer immunology research, 2022, 09-01, Volume: 10, Issue:9

    Topics: Animals; Cell Line, Tumor; Deferoxamine; Immunologic Factors; Immunotherapy; Mice; Positron-Emission Tomography; Radioisotopes; Tissue Distribution; Zirconium

2022
The impact of zirconium-89 solution formulation on the efficiency of [
    Journal of labelled compounds & radiopharmaceuticals, 2022, Volume: 65, Issue:13

    Topics: Chlorides; Citrates; Deferoxamine; Oxalates; Positron-Emission Tomography; Zirconium

2022
New Long-Acting [
    Journal of medicinal chemistry, 2023, 06-22, Volume: 66, Issue:12

    Topics: Cell Line, Tumor; Chelating Agents; Deferoxamine; Kidney; Positron-Emission Tomography; Tissue Distribution; Zirconium

2023
Synthesis of Modular Desferrioxamine Analogues and Evaluation of Zwitterionic Derivatives for Zirconium Complexation.
    ChemMedChem, 2023, Jul-03, Volume: 18, Issue:13

    Topics: Chelating Agents; Deferoxamine; Positron-Emission Tomography; Radioisotopes; Zirconium

2023
Site-Specific
    Bioconjugate chemistry, 2023, 10-18, Volume: 34, Issue:10

    Topics: Animals; Cell Line, Tumor; Chelating Agents; Deferoxamine; Gallium Radioisotopes; Immunoconjugates; Methionine; Mice; Neoplasms; Positron-Emission Tomography; Racemethionine; Tissue Distribution; Trastuzumab; Zirconium

2023