zirconium has been researched along with deferoxamine in 70 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (1.43) | 18.7374 |
1990's | 3 (4.29) | 18.2507 |
2000's | 2 (2.86) | 29.6817 |
2010's | 44 (62.86) | 24.3611 |
2020's | 20 (28.57) | 2.80 |
Authors | Studies |
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Haisma, HJ; Herscheid, JD; Meijs, WE; Pinedo, HM | 1 |
Brown, DJ; Dawborn, JK; Ham, KN; Johnson, CI; Nelson, S; Xipell, JM | 1 |
Haisma, HJ; Herscheid, JD; Klok, RP; Meijs, WE; Pinedo, HM; Van den Oever, K; Van der Schors, R; Wijbrandts, R | 1 |
Haisma, HJ; Herscheid, JD; Kievit, E; Klok, RP; Meijs, WE; Pinedo, HM; van Gog, FB | 1 |
Igarashi, S; Kubota, T; Takagai, Y; Takahashi, A; Yamaguchi, H | 1 |
Holland, JP; Lewis, JS; Sheh, Y | 1 |
Budde, M; Jurek, P; Kiefer, GE; Perk, LR; van Dongen, GA; Visser, GW; Vosjan, MJ | 2 |
Caldas-Lopes, E; Chiosis, G; Divilov, V; Holland, JP; Lewis, JS; Longo, VA; Taldone, T; Zatorska, D | 1 |
Grimm, J; Holland, JP; Lewis, JS; Ruggiero, A | 1 |
Holland, JP; Lewis, JS; May, C; McDevitt, MR; Ruggiero, A; Scheinberg, DA; Sprinkle, SR; Villa, CH | 1 |
Gebhardt, P; Grosse-Gehling, P; Irmler, I; Kamradt, T; Khalid, M; Opfermann, T; Preusche, S; Saluz, HP; Steinbach, J; Walther, M; Würbach, L | 1 |
Carlin, S; Divilov, V; Heneweer, C; Holland, JP; Lewis, JS | 1 |
Barnhart, TE; Cai, W; Engle, JW; Hong, H; Leigh, BR; Liu, G; Nickles, RJ; Severin, GW; Yang, Y; Zhang, Y | 1 |
Gambhir, SS; Habte, F; Natarajan, A | 1 |
Evans, MJ; Holland, JP; Lewis, JS; Rice, SL; Sawyers, CL; Wongvipat, J | 1 |
Brechbiel, MW; Deschamps, JR; Guérard, F; Lee, YS; Szajek, LP; Tripier, R | 1 |
Aggeler, R; Agnew, BJ; Chen, A; Davis, CB; Kang, HC; Lewis, JS; Zeglis, BM | 1 |
Fischer, G; Schirrmacher, R; Seibold, U; Wängler, B; Wängler, C | 1 |
Brechbiel, MW; Guérard, F; Lee, YS | 1 |
Bhadrasetty, V; Chaudhary, A; Choyke, P; Coble, V; Elbuluk, O; Griffiths, GL; Histed, S; Jagoda, EM; Kuo, F; Lane, K; Paik, CH; St Croix, B; Szajek, LP; Szot, C; Vasalatiy, O; Williams, MR; Wong, K; Wu, H; Xu, B | 1 |
Bauman, A; Blacque, O; Fischer, CA; Gasser, G; Häussinger, D; Mari, C; Mindt, TL; Patra, M | 1 |
Berry, DJ; Blower, PJ; Cooper, MS; Hider, RC; Ma, MT; Ma, Y; Meszaros, LK; Paterson, BM | 1 |
Ferrara, KW; Ingham, ES; Mahakian, LM; Meares, CF; Qin, S; Seo, JW; Tam, S | 1 |
Lewis, JS; Zeglis, BM | 1 |
Bauman, A; Fischer, CA; Mindt, TL; Valverde, IE; Vomstein, S | 1 |
Abdel-Atti, D; Houghton, JL; Lewis, JS; Sawada, R; Scholz, WW; Zeglis, BM | 1 |
Del Pozzo, L; Holland, JP; Illert, AL; Klingeberg, C; Maecke, HR; Meyer, PT; Rylova, SN; Tönnesmann, R | 1 |
Burton-Pye, BP; Cicek, HT; Deri, MA; Francesconi, LC; Hu, C; Kozlowski, P; Lewis, JS; Ponnala, S | 1 |
Escuin-Ordinas, H; McCracken, MN; Mok, S; Ribas, A; Salazar, FB; Tavaré, R; Witte, ON; Wu, AM; Zettlitz, KA | 1 |
Balatoni, JA; González-Lepera, C; Lin, M; Mukhopadhyay, U; Waligorski, GJ | 1 |
Abdel-Atti, D; Aggeler, R; Agnew, BJ; Houghton, JL; Lewis, JS; Sawada, R; Scholz, WW; Zeglis, BM | 1 |
Boros, E; Caravan, P; Carlson, JC; Meimetis, LG; Ran, C; Weissleder, R | 1 |
Augustyns, K; De Vijlder, T; Dedeurwaerdere, S; Fissers, J; Joossens, J; Mercken, M; Pemberton, DJ; Staelens, S; Stroobants, S; Van Broeck, B; Van Der Veken, P; Waldron, AM; Wyffels, L | 1 |
Burvenich, IJ; Gan, HK; Gong, S; Guo, N; Hasegawa, J; Kotsuma, M; Lee, FT; Lee, ST; O'Keefe, GJ; Parakh, S; Rigopoulos, A; Scott, AM; Senaldi, G; Tochon-Danguy, H | 1 |
Boutin, H; Brown, G; Ellis, B; Fairclough, M; Jones, AK; Locatelli, P; McMahon, A; Prenant, C | 1 |
Glassner, M; Hoogenboom, R; Monnery, BD; Staelens, S; Stroobants, S; Verbrugghen, T; Wyffels, L | 1 |
Cullinane, C; Donnelly, PS; Hicks, RJ; Roselt, P; Rudd, SE | 1 |
Adamzek, K; Bolijn, M; Haselberg, R; Houthoff, HJ; Merkul, E; Montserrat, V; Muns, JA; Sijbrandi, NJ; Somsen, GW; Steverink, PJ; van Dongen, GA; Waalboer, DC | 1 |
Bénard, F; Colpo, N; Dias, GM; Lin, KS; Rousseau, J; Zhang, C; Zhang, Z | 1 |
Blower, PJ; Li, N; Pham, TT; Yan, R; Yu, Z | 1 |
Boerman, O; Denat, F; Goncalves, V; Heskamp, S; Raavé, R; Rijpkema, M | 1 |
Andersson, KG; Decristoforo, C; Garousi, J; Löfblom, J; Mitran, B; Orlova, A; Oroujeni, M; Summer, D; Tolmachev, V; Vorobyeva, A | 1 |
Codd, R; Gotsbacher, MP; Richardson-Sanchez, T; Telfer, TJ | 1 |
Beckford Vera, DR; Bixby, LM; Dunn, SS; Glatt, DM; Kim, WY; Parrott, MC; Saito, R; Serody, JS; Smith, CC; Vincent, BG | 1 |
Bhatt, NB; Pandya, DN; Wadas, TJ | 1 |
Al-Dulaymi, M; Badea, I; Fonge, H; Hajdu, I; Makhlouf, A; Michel, D; Solomon, VR; Wasan, KM | 1 |
Ahn, SH; Alford, VM; Boros, E; Laughlin, ST; Preston, AN; Thach, D; Vaughn, BA | 1 |
Adumeau, P; Fung, K; Rodriguez, C; Sharma, SK; Vivier, D; Zeglis, BM | 1 |
Gumienna-Kontecka, E; Toporivska, Y | 1 |
Cho, EH; Choi, K; Chung, J; Chung, JH; Ju, JM; Kim, H; Kim, SY; Lee, SH; Lee, SJ; Oh, SJ; Ryu, JS; Sheen, JH; Soh, H | 1 |
Fay, R; Holland, JP; Klingler, S | 1 |
Holland, JP | 1 |
Aulsebrook, ML; Brandt, M; Cowell, J; Gasser, G; Mindt, TL | 1 |
Boffi, A; Bonamore, A; Braniewska, A; Cerutti, G; Clarkson, R; Dabkowski, AM; Kiraga, Ł; Król, M; Kucharzewska, P; Montemiglio, LC; Paisey, SJ; Rygiel, TP; Sas, Z; Savino, C; Seaton, G; Strzemecki, D; Taciak, B; Turnham, D | 1 |
Cullinane, C; Donnelly, PS; Haskali, MB; Hicks, RJ; Noor, A; Roselt, PD; Rudd, SE; Van Zuylekom, JK; Waldeck, K; Wheatcroft, MP; Yan, E | 1 |
Lewis, JS; Price, EW; Raheem, SJ; Salih, AK; Sarbisheh, EK | 1 |
Beaino, W; Bolijn, MJ; Brown, K; Chomet, M; Cowell, J; Gasser, G; Gill, H; Marik, J; Mindt, TL; Poot, AJ; Schreurs, M; van Dongen, GAMS; Verlaan, M; Vugts, DJ; Williams, S; Windhorst, AD | 1 |
Cullinane, C; Donnelly, PS; Haskali, MB; Hicks, RJ; Noor, A; Roselt, PD; Rudd, SE; Van Zuylekom, JK; Wheatcroft, M; Yan, E | 1 |
Earley, DF; Fay, R; Guillou, A; Holland, JP; Klingler, S; Nisli, E; Nüesch, LJ | 1 |
Bellotti, D; Remelli, M | 1 |
Carlsten, M; Friberger, I; Goos, JACM; Han, J; Harris, RA; Holmin, S; Jussing, E; Kaipe, H; Lambert, M; Samén, E; Siikanen, J; Tran, TA | 1 |
Fortin, MA; Lagueux, J; Laprise-Pelletier, M; Lemay, S; Omar, MM; Tuduri, L | 1 |
Ida, H; Imura, R; Ishioka, NS; Sasaki, I; Watanabe, S | 1 |
Bianchi, A; Boscaro, F; Savastano, M | 1 |
Babazada, H; Chang, B; Edwards, KJ; Farwell, MD; Lohith, K; Park, DH; Sellmyer, MA | 1 |
Bubenshchikov, V; Larenkov, A; Makichyan, A | 1 |
Bjørnsdottir, I; Boswinkel, M; Fernandes, EFA; Glendorf, T; Gustafsson, MBF; Heskamp, S; Raavé, R; Rodríguez, D; Wilbs, J | 1 |
Frangioni, JV; Maison, W; Münzmay, M; Outzen, L | 1 |
Aprile, FA; Ge, Y; Long, NJ; Ma, MT; Pham, TT; Yue, TTC | 1 |
5 review(s) available for zirconium and deferoxamine
Article | Year |
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(89)Zr, a radiometal nuclide with high potential for molecular imaging with PET: chemistry, applications and remaining challenges.
Topics: Deferoxamine; Isotope Labeling; Molecular Imaging; Positron-Emission Tomography; Radiopharmaceuticals; Zirconium | 2013 |
Topics: Animals; Chelating Agents; Deferoxamine; Drug Delivery Systems; Drug Discovery; Humans; Immunoconjugates; Neoplasms; Positron-Emission Tomography; Radiochemistry; Radioisotopes; Zirconium | 2017 |
Advances in the Chemical Biology of Desferrioxamine B.
Topics: Anti-Bacterial Agents; Biochemistry; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Deferoxamine; Fluorescent Dyes; Humans; Hydrolysis; Iron Chelating Agents; Positron-Emission Tomography; Siderophores; Zirconium | 2018 |
Recent Advances in Zirconium-89 Chelator Development.
Topics: Animals; Chelating Agents; Deferoxamine; Humans; Molecular Structure; Positron-Emission Tomography; Radioisotopes; Zirconium | 2018 |
Deferoxamine B: A Natural, Excellent and Versatile Metal Chelator.
Topics: Animals; Antineoplastic Agents; Chelating Agents; Chemistry, Pharmaceutical; COVID-19 Drug Treatment; Deferoxamine; Electrochemistry; Electrolytes; Humans; Hydrogen-Ion Concentration; Ions; Iron; Iron Chelating Agents; Iron Overload; Kinetics; Ligands; Metals; Neoplasms; Potentiometry; SARS-CoV-2; Temperature; Zirconium | 2021 |
65 other study(ies) available for zirconium and deferoxamine
Article | Year |
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Evaluation of desferal as a bifunctional chelating agent for labeling antibodies with Zr-89.
Topics: Antibodies; Chelating Agents; Deferoxamine; Evaluation Studies as Topic; Isotope Labeling; Radioisotopes; Zirconium | 1992 |
Dialysis osteomalacia: a possible role for zirconium as well as aluminium.
Topics: Chronic Kidney Disease-Mineral and Bone Disorder; Deferoxamine; Glomerulonephritis; Humans; Osteomalacia; Zirconium | 1985 |
A facile method for the labeling of proteins with zirconium isotopes.
Topics: Animals; Cattle; Chelating Agents; Deferoxamine; Drug Stability; Female; Isotope Labeling; Mice; Mice, Inbred BALB C; Protein Binding; Radioisotopes; Serum Albumin, Bovine; Tissue Distribution; Zirconium | 1996 |
Zirconium-labeled monoclonal antibodies and their distribution in tumor-bearing nude mice.
Topics: Animals; Antibodies, Monoclonal; Deferoxamine; Immunoconjugates; Isotope Labeling; Mice; Mice, Nude; Neoplasms; Tissue Distribution; Tomography, Emission-Computed; Transplantation, Heterologous; Tumor Cells, Cultured; Zirconium | 1997 |
Adsorption behaviors of high-valence metal ions on desferrioxamine B immobilization nylon 6,6 chelate fiber under highly acidic conditions.
Topics: Adsorption; Biochemistry; Caprolactam; Deferoxamine; Hafnium; Hydrogen-Ion Concentration; Ions; Metals; Models, Chemical; Polymers; Siderophores; Solvents; Surface Properties; Zirconium | 2007 |
Standardized methods for the production of high specific-activity zirconium-89.
Topics: Animals; Benchmarking; Chelating Agents; Cyclotrons; Deferoxamine; Humans; Hydroxamic Acids; Ligands; Male; Mice; Positron-Emission Tomography; Radioisotopes; Reproducibility of Results; Zirconium | 2009 |
p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging.
Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Line, Tumor; Chelating Agents; Deferoxamine; Female; Humans; Isothiocyanates; Isotope Labeling; Metabolic Clearance Rate; Mice; Mice, Nude; Organ Specificity; Positron-Emission Tomography; Radioimmunodetection; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Zirconium | 2010 |
Measuring the pharmacodynamic effects of a novel Hsp90 inhibitor on HER2/neu expression in mice using Zr-DFO-trastuzumab.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzodioxoles; Cell Line, Tumor; Deferoxamine; Female; Genes, erbB-2; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, Nude; Purines; Tissue Distribution; Trastuzumab; Zirconium | 2010 |
Conjugation and radiolabeling of monoclonal antibodies with zirconium-89 for PET imaging using the bifunctional chelate p-isothiocyanatobenzyl-desferrioxamine.
Topics: Animals; Antibodies, Monoclonal; Chelating Agents; Deferoxamine; Head and Neck Neoplasms; Humans; Isothiocyanates; Mice; Mice, Nude; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Transplantation, Heterologous; Zirconium | 2010 |
Cerenkov luminescence imaging of medical isotopes.
Topics: Alpha Particles; Animals; Antibodies, Monoclonal; Beta Particles; Deferoxamine; Diagnostic Imaging; Drug Evaluation, Preclinical; Electrons; Female; Humans; Luminescence; Male; Mice; Neoplasm Transplantation; Neoplasms; Phantoms, Imaging; Positron-Emission Tomography; Prostate-Specific Antigen; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Zirconium | 2010 |
Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes.
Topics: Actinium; Adenocarcinoma; Animals; Cell Line, Tumor; Colonic Neoplasms; Deferoxamine; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice; Mice, Nude; Nanomedicine; Nanotubes, Carbon; Neovascularization, Pathologic; Positron-Emission Tomography; Radioimmunodetection; Radioimmunotherapy; Radioisotopes; Radiopharmaceuticals; Xenograft Model Antitumor Assays; Zirconium | 2010 |
Implementation of 89Zr production and in vivo imaging of B-cells in mice with 89Zr-labeled anti-B-cell antibodies by small animal PET/CT.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; B-Lymphocytes; Chelating Agents; Deferoxamine; Indoles; Isotope Labeling; Lymph Nodes; Mice; Mice, Inbred DBA; Mice, Nude; Positron-Emission Tomography; Quinoxalines; Radiography; Radioimmunodetection; Radioisotopes; Spectrometry, Gamma; Spleen; Tissue Distribution; Zirconium | 2011 |
Magnitude of enhanced permeability and retention effect in tumors with different phenotypes: 89Zr-albumin as a model system.
Topics: Animals; Autoradiography; Deferoxamine; Drug Stability; Humans; Image Processing, Computer-Assisted; Iron Chelating Agents; Male; Mice; Neoplasm Transplantation; Neoplasms; Permeability; Positron-Emission Tomography; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Serum Albumin; Tissue Distribution; Transplantation, Heterologous; Ultrasonography; Zirconium | 2011 |
Positron emission tomography imaging of CD105 expression with 89Zr-Df-TRC105.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Cell Line, Tumor; Deferoxamine; Endoglin; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Mice; Positron-Emission Tomography; Radioisotopes; Receptors, Cell Surface; Zirconium | 2012 |
Development of a novel long-lived immunoPET tracer for monitoring lymphoma therapy in a humanized transgenic mouse model.
Topics: Animals; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Cell Line, Tumor; Deferoxamine; Gene Expression; Humans; Immunoconjugates; Isothiocyanates; Lymphoma; Mice; Mice, Nude; Mice, Transgenic; Positron-Emission Tomography; Rituximab; Tissue Distribution; Zirconium | 2012 |
Annotating MYC status with 89Zr-transferrin imaging.
Topics: Animals; Deferoxamine; Male; Mice; Mice, Transgenic; Positron-Emission Tomography; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Proto-Oncogene Proteins c-myc; Radioisotopes; Radiopharmaceuticals; Receptors, Transferrin; Transferrin; Transplantation, Heterologous; Zirconium | 2012 |
Investigation of Zr(IV) and 89Zr(IV) complexation with hydroxamates: progress towards designing a better chelator than desferrioxamine B for immuno-PET imaging.
Topics: Chelating Agents; Coordination Complexes; Crystallography, X-Ray; Deferoxamine; Hydroxamic Acids; Models, Molecular; Molecular Structure; Positron-Emission Tomography; Quantum Theory; Radioisotopes; Zirconium | 2013 |
Enzyme-mediated methodology for the site-specific radiolabeling of antibodies based on catalyst-free click chemistry.
Topics: Animals; Antibodies; beta-Galactosidase; Binding Sites; Click Chemistry; Deferoxamine; Humans; Isotope Labeling; Male; Mice; Mice, Nude; Molecular Structure; Organometallic Compounds; Polysaccharides; Tumor Cells, Cultured; Zirconium | 2013 |
Rational design, synthesis, and evaluation of tetrahydroxamic acid chelators for stable complexation of zirconium(IV).
Topics: Chelating Agents; Coordination Complexes; Crystallography, X-Ray; Deferoxamine; Edetic Acid; Ferric Compounds; Hydroxamic Acids; Kinetics; Positron-Emission Tomography; Radioisotopes; Zirconium | 2014 |
Immuno-PET imaging of tumor endothelial marker 8 (TEM8).
Topics: Animals; Antibodies, Monoclonal, Humanized; Blotting, Western; Deferoxamine; Female; Humans; Immunoprecipitation; Mice; Mice, Nude; Microfilament Proteins; Molecular Imaging; Neoplasm Proteins; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Cell Surface; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Zirconium | 2014 |
An octadentate bifunctional chelating agent for the development of stable zirconium-89 based molecular imaging probes.
Topics: Cell Line, Tumor; Chelating Agents; Coordination Complexes; Crystallography, X-Ray; Deferoxamine; Humans; Molecular Conformation; Molecular Probes; Peptides; Radiopharmaceuticals; Zirconium | 2014 |
Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B.
Topics: Animals; Deferoxamine; Drug Stability; Female; Humans; Immunoconjugates; Isotope Labeling; Ligands; Male; Mice; Positron-Emission Tomography; Pyridines; Radioisotopes; Trastuzumab; Zirconium | 2015 |
The pharmacokinetics of Zr-89 labeled liposomes over extended periods in a murine tumor model.
Topics: Animals; Chemistry, Pharmaceutical; Deferoxamine; Disease Models, Animal; Drug Stability; Humans; Isotope Labeling; Liposomes; Mammary Neoplasms, Experimental; Mice; Phosphatidylethanolamines; Polyethylene Glycols; Positron-Emission Tomography; Radioisotopes; Tissue Distribution; Zirconium | 2015 |
The bioconjugation and radiosynthesis of 89Zr-DFO-labeled antibodies.
Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Deferoxamine; Heterografts; Humans; Immunoconjugates; Male; Mice; Mice, Nude; Positron-Emission Tomography; Prostatic Neoplasms; Radioisotopes; Radiopharmaceuticals; Zirconium | 2015 |
Development of 68Ga- and 89Zr-Labeled Exendin-4 as Potential Radiotracers for the Imaging of Insulinomas by PET.
Topics: Animals; Deferoxamine; Exenatide; Gallium Radioisotopes; Insulinoma; Isotope Labeling; Mice; Mice, Nude; Pancreatic Neoplasms; Peptides; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Venoms; Zirconium | 2015 |
Pretargeted Immuno-PET of Pancreatic Cancer: Overcoming Circulating Antigen and Internalized Antibody to Reduce Radiation Doses.
Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; Cell Line, Tumor; Copper Radioisotopes; Deferoxamine; Heterocyclic Compounds, 1-Ring; Humans; Mice; Neoplasm Transplantation; Pancreatic Neoplasms; Positron-Emission Tomography; Radiation Dosage; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Zirconium | 2016 |
Immuno-PET Imaging of CD30-Positive Lymphoma Using 89Zr-Desferrioxamine-Labeled CD30-Specific AC-10 Antibody.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Cell Line, Tumor; Deferoxamine; Drug Stability; Female; Humans; Immunoconjugates; Ki-1 Antigen; Lymphoma; Mice; Positron-Emission Tomography; Radiochemistry; Radioisotopes; Tissue Distribution; Zirconium | 2016 |
p-SCN-Bn-HOPO: A Superior Bifunctional Chelator for (89)Zr ImmunoPET.
Topics: Animals; Breast; Breast Neoplasms; Cell Line, Tumor; Chelating Agents; Deferoxamine; Female; Humans; Immunoconjugates; Mice, Nude; Models, Molecular; Positron-Emission Tomography; Pyridones; Tissue Distribution; Trastuzumab; Zirconium | 2015 |
An Effective Immuno-PET Imaging Method to Monitor CD8-Dependent Responses to Immunotherapy.
Topics: Animals; Antibodies, Bispecific; CD8 Antigens; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Deferoxamine; Disease Models, Animal; Humans; Immunoconjugates; Immunotherapy, Adoptive; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Zirconium | 2016 |
Semi-automated production of ⁸⁹Zr-oxalate/⁸⁹Zr-chloride and the potential of ⁸⁹Zr-chloride in radiopharmaceutical compounding.
Topics: Chemistry, Pharmaceutical; Chlorides; Cyclotrons; Deferoxamine; Humans; Immunoglobulin G; Isotope Labeling; Oxalates; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Solid Phase Extraction; Zirconium | 2016 |
Site-specifically labeled CA19.9-targeted immunoconjugates for the PET, NIRF, and multimodal PET/NIRF imaging of pancreatic cancer.
Topics: Animals; Antibodies, Monoclonal; CA-19-9 Antigen; Cell Line, Tumor; Deferoxamine; Disease Models, Animal; Female; Fluorescent Dyes; Humans; Immunoconjugates; Mice, Knockout; Mice, Nude; Microscopy, Fluorescence; Molecular Structure; Multimodal Imaging; Pancreatic Neoplasms; Positron-Emission Tomography; Radioisotopes; Reproducibility of Results; Sensitivity and Specificity; Spectroscopy, Near-Infrared; Tissue Distribution; Transplantation, Heterologous; Zirconium | 2015 |
Bioorthogonal Fluorophore Linked DFO-Technology Enabling Facile Chelator Quantification and Multimodal Imaging of Antibodies.
Topics: Animals; Antibodies, Monoclonal; Boron Compounds; Chelating Agents; Deferoxamine; Female; Fluorescent Dyes; Humans; Mice, Nude; Multimodal Imaging; Positron-Emission Tomography; Radioisotopes; Receptor, ErbB-2; Tissue Distribution; Trastuzumab; Xenograft Model Antitumor Assays; Zirconium | 2016 |
Synthesis and Evaluation of a Zr-89-Labeled Monoclonal Antibody for Immuno-PET Imaging of Amyloid-β Deposition in the Brain.
Topics: Amyloid beta-Peptides; Animals; Antibodies, Monoclonal; Autoradiography; Brain; Deferoxamine; Humans; Immunohistochemistry; Mice, Inbred C57BL; Mice, Transgenic; Positron-Emission Tomography; Staining and Labeling; Tissue Distribution; Zirconium | 2016 |
Molecular Imaging and Quantitation of EphA2 Expression in Xenograft Models with 89Zr-DS-8895a.
Topics: Animals; Antibodies, Monoclonal, Humanized; Cell Line, Tumor; Cell Transformation, Neoplastic; Deferoxamine; Female; Humans; Isothiocyanates; Mice; Pentetic Acid; Positron-Emission Tomography; Quality Control; Radioisotopes; Receptor, EphA2; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Zirconium | 2016 |
A new technique for the radiolabelling of mixed leukocytes with zirconium-89 for inflammation imaging with positron emission tomography.
Topics: Chitosan; Copper Radioisotopes; Deferoxamine; Humans; Inflammation; Isotope Labeling; Leukocytes; Nanoparticles; Positron-Emission Tomography; Radioisotopes; Zirconium | 2016 |
μPET imaging of the pharmacokinetic behavior of medium and high molar mass (89)Zr-labeled poly(2-ethyl-2-oxazoline) in comparison to poly(ethylene glycol).
Topics: Animals; Deferoxamine; Isothiocyanates; Kidney; Liver; Male; Mice, Inbred C57BL; Molecular Weight; Myocardium; Polyamines; Polyethylene Glycols; Positron-Emission Tomography; Radioisotopes; Siderophores; Tissue Distribution; Zirconium | 2016 |
A desferrioxamine B squaramide ester for the incorporation of zirconium-89 into antibodies.
Topics: Animals; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Cell Line, Tumor; Deferoxamine; Disease Models, Animal; Female; Humans; Isotope Labeling; Mice; Positron-Emission Tomography; Radioisotopes; Receptor, ErbB-2; Transplantation, Heterologous; Trastuzumab; Zirconium | 2016 |
A Novel Platinum(II)-Based Bifunctional ADC Linker Benchmarked Using 89Zr-Desferal and Auristatin F-Conjugated Trastuzumab.
Topics: Aminobenzoates; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Deferoxamine; Drug Design; Humans; Immunoconjugates; Mice; Oligopeptides; Platinum Compounds; Radioactive Tracers; Stomach Neoplasms; Trastuzumab; Xenograft Model Antitumor Assays; Zirconium | 2017 |
Design, synthesis and evaluation of novel bifunctional tetrahydroxamate chelators for PET imaging of
Topics: Animals; Antibodies, Monoclonal; Bone and Bones; Chelating Agents; Contrast Media; Coordination Complexes; Deferoxamine; Drug Design; Hydroxamic Acids; Isotope Labeling; Mice; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Trastuzumab; Zirconium | 2017 |
A generic
Topics: Animals; Deferoxamine; Drug Stability; Female; Folic Acid; Humans; Isotope Labeling; Liposomes; Mice; Mice, Nude; Nanoparticles; Positron-Emission Tomography; Quinolinic Acid; Radioisotopes; Radiopharmaceuticals; Rats; Tissue Distribution; Xenograft Model Antitumor Assays; Zirconium | 2017 |
Cyclic versus Noncyclic Chelating Scaffold for
Topics: Animals; Autoradiography; Cell Line, Tumor; Chelating Agents; Chromatography, High Pressure Liquid; Deferoxamine; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Female; Ferric Compounds; Humans; Hydroxamic Acids; Mice; Mice, Inbred BALB C; Positron-Emission Tomography; Radioisotopes; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xenograft Model Antitumor Assays; Zirconium | 2018 |
Immuno-PET imaging of tumor-infiltrating lymphocytes using zirconium-89 radiolabeled anti-CD3 antibody in immune-competent mice bearing syngeneic tumors.
Topics: Animals; Antibodies; Butylhydroxybutylnitrosamine; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Deferoxamine; Flow Cytometry; Lymphocytes, Tumor-Infiltrating; Mice, Inbred C57BL; Neoplasm Transplantation; Positron Emission Tomography Computed Tomography; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Urinary Bladder Neoplasms; Zirconium | 2018 |
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Topics: Animals; Cell Survival; Deferoxamine; Gene Expression Regulation; Gene Transfer Techniques; Genetic Therapy; Imaging, Three-Dimensional; Lipids; Mice, Nude; Nanoparticles; Neoplasms; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Surface-Active Agents; Tissue Distribution; Zirconium | 2018 |
Linear Desferrichrome-Linked Silicon-Rhodamine Antibody Conjugate Enables Targeted Multimodal Imaging of HER2 in Vitro and in Vivo.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Deferoxamine; Female; Heterografts; Humans; Immunoconjugates; In Vitro Techniques; Isotope Labeling; Mice; Mice, Nude; Positron Emission Tomography Computed Tomography; Radioisotopes; Radiopharmaceuticals; Receptor, ErbB-2; Rhodamines; Silicon; Tissue Distribution; Trastuzumab; Zirconium | 2019 |
The Impact of FcγRI Binding on Immuno-PET.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Deferoxamine; Female; Glycosylation; Humans; Immunoconjugates; Immunoglobulin G; In Vitro Techniques; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Positron-Emission Tomography; Radiopharmaceuticals; Receptor, ErbB-2; Receptors, IgG; Recombinant Proteins; Surface Plasmon Resonance; Tissue Distribution; Trastuzumab; Zirconium | 2019 |
The solution thermodynamic stability of desferrioxamine B (DFO) with Zr(IV).
Topics: Calorimetry; Coordination Complexes; Deferoxamine; Ligands; Siderophores; Thermodynamics; Zirconium | 2019 |
Feasibility of real-time in vivo 89Zr-DFO-labeled CAR T-cell trafficking using PET imaging.
Topics: Cell Proliferation; Cell Survival; Deferoxamine; Hematologic Neoplasms; Humans; Immunoconjugates; Isothiocyanates; Isotope Labeling; Jurkat Cells; Leukocytes, Mononuclear; Positron-Emission Tomography; Radioisotopes; Receptors, Antigen, T-Cell; Receptors, Chimeric Antigen; T-Lymphocytes; Tissue Distribution; Zirconium | 2020 |
Light-Induced Radiosynthesis of
Topics: Animals; Antibodies, Monoclonal; Azepines; Cell Line, Tumor; Chemistry Techniques, Synthetic; Deferoxamine; Half-Life; Humans; Light; Mice; Positron-Emission Tomography; Proto-Oncogene Proteins c-met; Radiochemistry; Radioisotopes; Tissue Distribution; Zirconium | 2020 |
Predicting the Thermodynamic Stability of Zirconium Radiotracers.
Topics: Chelating Agents; Coordination Complexes; Deferoxamine; Density Functional Theory; Ligands; Models, Molecular; Positron-Emission Tomography; Radioactive Tracers; Thermodynamics; Zirconium | 2020 |
Radiolabelling of the octadentate chelators DFO* and oxoDFO* with zirconium-89 and gallium-68.
Topics: Chelating Agents; Coordination Complexes; Deferoxamine; Gallium Radioisotopes; Molecular Structure; Radioisotopes; Radiopharmaceuticals; Zirconium | 2020 |
Biodistribution PET/CT Study of Hemoglobin-DFO-
Topics: Animals; Cell Line, Tumor; Coordination Complexes; Deferoxamine; Drug Carriers; Drug Delivery Systems; Female; Hemoglobins; Humans; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Models, Molecular; Positron Emission Tomography Computed Tomography; Radioisotopes; Tissue Distribution; Zirconium | 2020 |
Bivalent Inhibitors of Prostate-Specific Membrane Antigen Conjugated to Desferrioxamine B Squaramide Labeled with Zirconium-89 or Gallium-68 for Diagnostic Imaging of Prostate Cancer.
Topics: Animals; Antigens, Surface; Cell Line, Tumor; Cell Transformation, Neoplastic; Deferoxamine; Enzyme Inhibitors; Gallium Radioisotopes; Glutamate Carboxypeptidase II; Humans; Isotope Labeling; Male; Mice; Positron Emission Tomography Computed Tomography; Prostatic Neoplasms; Quinine; Radioisotopes; Tissue Distribution; Zirconium | 2020 |
A High-Denticity Chelator Based on Desferrioxamine for Enhanced Coordination of Zirconium-89.
Topics: Coordination Complexes; Deferoxamine; Density Functional Theory; Iron Chelating Agents; Zirconium | 2020 |
Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinical
Topics: Animals; Cell Line, Tumor; Chelating Agents; Deferoxamine; Mice; Positron-Emission Tomography; Radioisotopes; Tissue Distribution; Zirconium | 2021 |
Imaging Somatostatin Positive Tumors with Tyr
Topics: Animals; Deferoxamine; Gallium Radioisotopes; Mice; Octreotide; Quinine; Radioisotopes; Somatostatin; Zirconium | 2021 |
The Influence of a Polyethylene Glycol Linker on the Metabolism and Pharmacokinetics of a
Topics: Animals; Antibodies, Monoclonal; Chromatography, High Pressure Liquid; Chromatography, Liquid; Deferoxamine; Immunoconjugates; Mice; Mice, Nude; Polyethylene Glycols; Positron-Emission Tomography; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Zirconium | 2021 |
Optimisation of the Synthesis and Cell Labelling Conditions for [
Topics: Animals; Cell Line, Tumor; Deferoxamine; Oxyquinoline; Positron-Emission Tomography; Radioisotopes; Rats; Tissue Distribution; Zirconium | 2021 |
A diffusion cell adapted to nuclear imaging instruments for the measurement of molecular release and pharmacokinetics across membranes.
Topics: Deferoxamine; Positron-Emission Tomography; Radioisotopes; Renal Dialysis; Tissue Distribution; Zirconium | 2021 |
Re-Evaluations of Zr-DFO Complex Coordination Chemistry for the Estimation of Radiochemical Yields and Chelator-to-Antibody Ratios of
Topics: Antibodies, Monoclonal; Cell Line, Tumor; Chelating Agents; Deferoxamine; Humans; Isotope Labeling; Positron-Emission Tomography; Radiochemistry; Radioisotopes; Zirconium | 2021 |
Metal Coordination Properties of a Chromophoric Desferrioxamine (DFO) Derivative: Insight on the Coordination Stoichiometry and Thermodynamic Stability of Zr
Topics: Chelating Agents; Chemical Phenomena; Coordination Complexes; Deferoxamine; Models, Theoretical; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Spectrum Analysis; Thermodynamics; Zirconium | 2021 |
Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation.
Topics: Animals; Cell Line, Tumor; Deferoxamine; Immunologic Factors; Immunotherapy; Mice; Positron-Emission Tomography; Radioisotopes; Tissue Distribution; Zirconium | 2022 |
The impact of zirconium-89 solution formulation on the efficiency of [
Topics: Chlorides; Citrates; Deferoxamine; Oxalates; Positron-Emission Tomography; Zirconium | 2022 |
New Long-Acting [
Topics: Cell Line, Tumor; Chelating Agents; Deferoxamine; Kidney; Positron-Emission Tomography; Tissue Distribution; Zirconium | 2023 |
Synthesis of Modular Desferrioxamine Analogues and Evaluation of Zwitterionic Derivatives for Zirconium Complexation.
Topics: Chelating Agents; Deferoxamine; Positron-Emission Tomography; Radioisotopes; Zirconium | 2023 |
Site-Specific
Topics: Animals; Cell Line, Tumor; Chelating Agents; Deferoxamine; Gallium Radioisotopes; Immunoconjugates; Methionine; Mice; Neoplasms; Positron-Emission Tomography; Racemethionine; Tissue Distribution; Trastuzumab; Zirconium | 2023 |