Page last updated: 2024-08-24

ziprasidone and valproic acid

ziprasidone has been researched along with valproic acid in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (38.46)29.6817
2010's15 (57.69)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Freeman, MP; Gelenberg, AJ; Gnanadesikan, M1
Coffey, B1
Jaffe, R; Leavitt, R; Wind, T1
Bryois, Ch; Sahli, Ch1
Geddes, J1
Jebaraj, P; Rajkumar, AP; Tharyan, P1
Bowden, CL; Ice, KS; Schwartz, JH; Versavel, M; Vieta, E; Wang, PP1
Chappell, PB; Gurtovaya, O; Ice, KS; Kasuba, B; Sachs, GS; Schwartz, JH; Vanderburg, DG1
Calabrese, JR; Ice, KS; Karayal, ON; Kemp, DE; Pappadopulos, E; Sachs, GS; Siu, CO; Vieta, E1
Akritopoulou, K; Anestakis, D; Ekonomopoulou, MT; Iakovidou-Kritsi, Z; Karapidaki, I1
Bowden, CL; Gundapaneni, BK; Karayal, ON; O'Gorman, C; Schwartz, JH1
Mandel, FS; Masand, PS; O'Gorman, C; Pae, CU1
Bachinsky, M; Cavus, I; Karayal, ON; Kolluri, S; Sachs, GS; Vanderburg, DG1
Bachinsky, M; Cavus, I; Edman, S; Karayal, ON; Kolluri, S; Sachs, GS; Vanderburg, DG1
Tohen, M1
Bahk, WM; Kim, MD; Kwon, YJ; Lee, HB; Lee, JG; Woo, YS; Yoon, BH1
Cornelius, V; Smith, L; Taylor, DM; Young, AH1
Carvalho, AF; Hidalgo-Mazzei, D; Murru, A; Pacchiarotti, I; Samalin, L; Verdolini, N; Vieta, E; Young, AH1
Cao, D; Hong, Y; Huang, W; Wang, L; Wei, H; Xu, J; Zhang, J1

Reviews

8 review(s) available for ziprasidone and valproic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.
    Bipolar disorders, 2003, Volume: 5, Issue:3

    Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid

2003
[Psychotropics and weight gain].
    Praxis, 2004, Aug-25, Volume: 93, Issue:35

    Topics: Adolescent; Adult; Amisulpride; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Body Mass Index; Child; Clozapine; Dibenzothiazepines; Double-Blind Method; Female; Fructose; Haloperidol; Humans; Imidazoles; Indoles; Male; Obesity; Olanzapine; Piperazines; Placebos; Psychotropic Drugs; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Socioeconomic Factors; Sulpiride; Thiazoles; Time Factors; Topiramate; Valproic Acid; Weight Gain

2004
Bipolar disorder.
    Clinical evidence, 2005, Issue:13

    Topics: Antidepressive Agents; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Chlorpromazine; Cognitive Behavioral Therapy; Humans; Lithium Carbonate; Olanzapine; Piperazines; Thiazoles; Valproic Acid

2005
The efficacy and safety of switching to ziprasidone from olanzapine in patients with bipolar I disorder: an 8-week, multicenter, open-label study.
    Clinical drug investigation, 2013, Volume: 33, Issue:10

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Drug Substitution; Drug Therapy, Combination; Dyslipidemias; Female; Humans; Lithium; Male; Middle Aged; Olanzapine; Piperazines; Prospective Studies; Thiazoles; Treatment Outcome; Valproic Acid; Young Adult

2013
Comparative efficacy and acceptability of drug treatments for bipolar depression: a multiple-treatments meta-analysis.
    Acta psychiatrica Scandinavica, 2014, Volume: 130, Issue:6

    Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Bipolar Disorder; Depression; Dibenzothiazepines; Drug Therapy, Combination; Fluoxetine; Humans; Isoindoles; Lamotrigine; Lithium Compounds; Lurasidone Hydrochloride; Monoamine Oxidase Inhibitors; Olanzapine; Piperazines; Quetiapine Fumarate; Quinolones; Randomized Controlled Trials as Topic; Risperidone; Selective Serotonin Reuptake Inhibitors; Thiazoles; Treatment Outcome; Triazines; Valproic Acid

2014
Mixed states in bipolar and major depressive disorders: systematic review and quality appraisal of guidelines.
    Acta psychiatrica Scandinavica, 2018, Volume: 138, Issue:3

    Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Bipolar Disorder; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Lithium; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Practice Guidelines as Topic; Quetiapine Fumarate; Thiazoles; Valproic Acid

2018
A cumulative Bayesian network meta-analysis on the comparative efficacy of pharmacotherapies for mania over the last 40 years.
    Psychopharmacology, 2022, Volume: 239, Issue:10

    Topics: Adult; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Carbamazepine; Dibenzocycloheptenes; Haloperidol; Humans; Lithium; Mania; Network Meta-Analysis; Olanzapine; Paliperidone Palmitate; Pharmaceutical Preparations; Piperazines; Quetiapine Fumarate; Risperidone; Tamoxifen; Thiazoles; Valproic Acid

2022

Trials

7 trial(s) available for ziprasidone and valproic acid

ArticleYear
Ziprasidone plus a mood stabilizer in subjects with bipolar I disorder: a 6-month, randomized, placebo-controlled, double-blind trial.
    The Journal of clinical psychiatry, 2010, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Aged; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium Compounds; Male; Middle Aged; Piperazines; Placebos; Psychiatric Status Rating Scales; Severity of Illness Index; Thiazoles; Treatment Outcome; Valproic Acid

2010
Efficacy and safety of adjunctive oral ziprasidone for acute treatment of depression in patients with bipolar I disorder: a randomized, double-blind, placebo-controlled trial.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aged; Antimanic Agents; Bipolar Disorder; Depressive Disorder, Major; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lithium; Male; Middle Aged; Piperazines; Serotonin Antagonists; Thiazoles; Treatment Outcome; Triazines; Valproic Acid; Young Adult

2011
Ziprasidone with adjunctive mood stabilizer in the maintenance treatment of bipolar I disorder: long-term changes in weight and metabolic profiles.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2012, Volume: 22, Issue:2

    Topics: Adjuvants, Immunologic; Antipsychotic Agents; Bipolar Disorder; Body Weight; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium Chloride; Longitudinal Studies; Male; Metabolic Diseases; Metabolome; Piperazines; Psychiatric Status Rating Scales; Thiazoles; Valproic Acid

2012
Characterizing relapse prevention in bipolar disorder with adjunctive ziprasidone: clinical and methodological implications.
    Journal of affective disorders, 2013, Jan-10, Volume: 144, Issue:1-2

    Topics: Antipsychotic Agents; Bipolar Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Lithium; Piperazines; Secondary Prevention; Thiazoles; Treatment Outcome; Valproic Acid

2013
Achieving and sustaining remission in bipolar I disorder with ziprasidone : a post hoc analysis of a 24-week, double-blind, placebo-controlled study.
    Clinical drug investigation, 2012, Volume: 32, Issue:11

    Topics: Adult; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium Compounds; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Remission Induction; Thiazoles; Time Factors; Treatment Outcome; Valproic Acid

2012
Adjunctive oral ziprasidone in patients with acute mania treated with lithium or divalproex, part 1: results of a randomized, double-blind, placebo-controlled trial.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Antimanic Agents; Basal Ganglia Diseases; Bipolar Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lithium Carbonate; Male; Middle Aged; Piperazines; Psychiatric Status Rating Scales; Thiazoles; Treatment Outcome; Valproic Acid; Young Adult

2012
Adjunctive oral ziprasidone in patients with acute mania treated with lithium or divalproex, part 2: influence of protocol-specific eligibility criteria on signal detection.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Antimanic Agents; Bipolar Disorder; Diagnosis, Computer-Assisted; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Interview, Psychological; Lithium Carbonate; Male; Middle Aged; Patient Selection; Piperazines; Psychiatric Status Rating Scales; Psychometrics; Research Design; Signal Detection, Psychological; Thiazoles; Treatment Outcome; Valproic Acid; Young Adult

2012

Other Studies

11 other study(ies) available for ziprasidone and valproic acid

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Clinical case presentation: therapeutic challenges in adolescent-onset bipolar disorder.
    Journal of child and adolescent psychopharmacology, 2003,Winter, Volume: 13, Issue:4

    Topics: Adolescent; Aggression; Anti-Anxiety Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clonazepam; Diagnosis, Differential; Education; Family; GABA Modulators; Haloperidol; Hospitalization; Humans; Irritable Mood; Lithium; Lorazepam; Male; Piperazines; Psychiatric Status Rating Scales; Sexual Behavior; Thiazoles; Valproic Acid

2003
QTc prolongation in multiple drug overdose.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:3

    Topics: Adult; Bupropion; Drug Overdose; Fluoxetine; Humans; Long QT Syndrome; Male; Piperazines; Psychotic Disorders; Thiazoles; Valproic Acid

2004
Multi-drug overdose risperidone, ziprasidone, valproate, trihexyphenidyl, and clonazepam.
    The Journal of the Association of Physicians of India, 2007, Volume: 55

    Topics: Adult; Antipsychotic Agents; Clonazepam; Drug Overdose; Drug Prescriptions; Female; Humans; Piperazines; Polypharmacy; Risperidone; Schizophrenia, Paranoid; Thiazoles; Trihexyphenidyl; Valproic Acid

2007
Cytogenetic effects of valproic acid and ziprasidone in human lymphocyte cultures.
    Neuropsychobiology, 2011, Volume: 64, Issue:4

    Topics: Adult; Antipsychotic Agents; Cell Proliferation; Cytogenetic Analysis; Drug Synergism; Female; Humans; Lymphocytes; Male; Piperazines; Primary Cell Culture; Sister Chromatid Exchange; Thiazoles; Valproic Acid

2011
Methodologies to avoid the enrollment of ineligible patients in clinical trials.
    The Journal of clinical psychiatry, 2012, Volume: 73, Issue:11

    Topics: Antimanic Agents; Bipolar Disorder; Female; Humans; Lithium Carbonate; Male; Patient Selection; Piperazines; Signal Detection, Psychological; Thiazoles; Valproic Acid

2012