Page last updated: 2024-08-24

ziprasidone and isoxazoles

ziprasidone has been researched along with isoxazoles in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (47.37)29.6817
2010's9 (47.37)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Cui, D; Kamel, A; Miceli, JJ; Prakash, C; Tweedie, D; Whalen, RD1
Albert, MJ; Baldessarini, RJ; Centorrino, F; Kelleher, JP1
Kalkman, HO; Loetscher, E1
Bartlett, MG; Terry, AV; Zhang, G1
Cutler, AJ; Hamilton, J; Kalali, AH; Weiden, PJ; Wolfgang, CD1
Hamilton, J; Heaton, C; Lannan, R; Lavedan, C; Licamele, L; Mack, K; Polymeropoulos, MH; Thompson, A; Volpi, S; Wolfgang, CD1
Hamilton, JB; Heaton, C; Lannan, R; Lavedan, C; Licamele, L; Mack, K; Polymeropoulos, MH; Volpi, S; Wolfgang, CD1
Clement, HW; Heiser, P; Hemmeter, UM; Krieg, JC; Schmidt, AJ; Schulz, E; Vedder, H1
Kumar, R; Sachdev, PS1
Lavedan, C; Licamele, L; Malhotra, AK; Potkin, SG; Volpi, S1
Lavedan, C; Thompson, A; Volpi, S1
Newman, M1
Citrome, L; Hochfeld, M; Meng, X; Stahl, SM1
Hochfeld, M; Meng, X; Potkin, SG; Preskorn, S1
Cutler, AJ; Kalali, AH; Kunovac, J; Mattingly, GW; Meng, X1
Dai, G; Zhang, Y1
Morrissette, DA; Stahl, SM1
Geerts, H; Potkin, S; Roberts, P; Spiros, A1
Crippa, A; Davis, JM; Leucht, S; Orsini, N; Patel, MX; Siafis, S1

Reviews

4 review(s) available for ziprasidone and isoxazoles

ArticleYear
Advances in atypical antipsychotics for the treatment of schizophrenia: new formulations and new agents.
    CNS drugs, 2002, Volume: 16, Issue:4

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clinical Trials as Topic; Clozapine; Dosage Forms; Humans; Isoxazoles; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quinolones; Risperidone; Schizophrenia; Thiazoles

2002
Akathisia and second-generation antipsychotic drugs.
    Current opinion in psychiatry, 2009, Volume: 22, Issue:3

    Topics: Amisulpride; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Clozapine; Dibenzothiazepines; Humans; Isoxazoles; Olanzapine; Piperazines; Piperidines; Prevalence; Psychomotor Agitation; Psychotic Disorders; Quetiapine Fumarate; Quinolones; Risk Factors; Risperidone; Sulpiride; Thiazoles

2009
Treating the violent patient with psychosis or impulsivity utilizing antipsychotic polypharmacy and high-dose monotherapy.
    CNS spectrums, 2014, Volume: 19, Issue:5

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brain; Clozapine; Dibenzocycloheptenes; Drug Therapy, Combination; Heterocyclic Compounds, 4 or More Rings; Humans; Impulsive Behavior; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Polypharmacy; Psychotic Disorders; Quetiapine Fumarate; Receptors, Dopamine D2; Risperidone; Thiazoles; Violence

2014
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
    The American journal of psychiatry, 2020, 04-01, Volume: 177, Issue:4

    Topics: Acute Disease; Administration, Oral; Antipsychotic Agents; Aripiprazole; Clozapine; Delayed-Action Preparations; Dose-Response Relationship, Drug; Haloperidol; Humans; Imidazoles; Indoles; Isoxazoles; Lurasidone Hydrochloride; Olanzapine; Paliperidone Palmitate; Piperazines; Piperidines; Quetiapine Fumarate; Quinolones; Risperidone; Schizophrenia; Schizophrenic Psychology; Thiazoles; Thiophenes

2020

Trials

9 trial(s) available for ziprasidone and isoxazoles

ArticleYear
Four-week, double-blind, placebo- and ziprasidone-controlled trial of iloperidone in patients with acute exacerbations of schizophrenia.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2 Suppl 1

    Topics: Acute Disease; Adolescent; Adult; Aged; Antipsychotic Agents; Double-Blind Method; Drug Administration Schedule; Female; Humans; Isoxazoles; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Schizophrenia; Thiazoles; Treatment Outcome

2008
Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study.
    Molecular psychiatry, 2009, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Basic Helix-Loop-Helix Transcription Factors; Double-Blind Method; Female; Genome-Wide Association Study; Glial Cell Line-Derived Neurotrophic Factor Receptors; Humans; Isoxazoles; Male; Middle Aged; Nerve Tissue Proteins; Pharmacogenetics; Piperazines; Piperidines; Polymorphism, Single Nucleotide; Pseudogenes; Receptors, AMPA; Schizophrenia; Tenascin; Thiazoles; Transcription Factors; Young Adult

2009
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia.
    Molecular psychiatry, 2009, Volume: 14, Issue:11

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Carrier Proteins; CELF Proteins; Cytoskeletal Proteins; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Gene Frequency; Genome-Wide Association Study; Genotype; Humans; Intracellular Signaling Peptides and Proteins; Isoxazoles; Linear Models; Linkage Disequilibrium; Long QT Syndrome; Male; Middle Aged; Neuregulins; Organic Anion Transporters; Pharmacogenetics; Phosphoproteins; Phosphotransferases (Alcohol Group Acceptor); Piperazines; Piperidines; Polymorphism, Single Nucleotide; RNA-Binding Proteins; Schizophrenia; Thiazoles; Young Adult

2009
Applicability of a genetic signature for enhanced iloperidone efficacy in the treatment of schizophrenia.
    The Journal of clinical psychiatry, 2009, Volume: 70, Issue:6

    Topics: Adult; Alleles; Antipsychotic Agents; Double-Blind Method; Female; Genetic Markers; Genotype; Humans; Isoxazoles; Likelihood Functions; Male; Middle Aged; Odds Ratio; Pharmacogenetics; Piperazines; Piperidines; Polymorphism, Single Nucleotide; Probability; Psychiatric Status Rating Scales; Psychometrics; Schizophrenia; Thiazoles; Treatment Outcome

2009
Absence of weight gain association with the HTR2C -759C/T polymorphism in patients with schizophrenia treated with iloperidone.
    Psychiatry research, 2010, Feb-28, Volume: 175, Issue:3

    Topics: Analysis of Variance; Antipsychotic Agents; Female; Follow-Up Studies; Gene Frequency; Genotype; Humans; Isoxazoles; Male; Piperazines; Piperidines; Polymorphism, Genetic; Receptor, Serotonin, 5-HT2C; Schizophrenia; Thiazoles; Weight Gain

2010
Efficacy of iloperidone in the short-term treatment of schizophrenia: a post hoc analysis of pooled patient data from four phase III, placebo- and active-controlled trials.
    Human psychopharmacology, 2012, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Labeling; Female; Haloperidol; Humans; Isoxazoles; Male; Middle Aged; Piperazines; Piperidines; Prospective Studies; Psychiatric Status Rating Scales; Psychotic Disorders; Risperidone; Schizophrenia; Thiazoles; Treatment Outcome; Young Adult

2012
A thorough QTc study of 3 doses of iloperidone including metabolic inhibition via CYP2D6 and/or CYP3A4 and a comparison to quetiapine and ziprasidone.
    Journal of clinical psychopharmacology, 2013, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dibenzothiazepines; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Electrocardiography; Enzyme Inhibitors; Female; Genotype; Heart Rate; Humans; Isoxazoles; Ketoconazole; Linear Models; Long QT Syndrome; Male; Middle Aged; Paroxetine; Pharmacogenetics; Phenotype; Piperazines; Piperidines; Quetiapine Fumarate; Thiazoles; United States; Young Adult

2013
Long-term safety and tolerability of iloperidone: results from a 25-week, open-label extension trial.
    CNS spectrums, 2013, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Substitution; Female; Humans; India; Isoxazoles; Longitudinal Studies; Male; Middle Aged; Piperazines; Piperidines; Psychiatric Status Rating Scales; Schizophrenia; Thiazoles; Time Factors; Treatment Outcome; United States; Young Adult

2013
Efficacy and metabolic influence of paliperidone ER, aripiprazole and ziprasidone to patients with first-episode schizophrenia through 52 weeks follow-up in China.
    Human psychopharmacology, 2012, Volume: 27, Issue:6

    Topics: Adult; Antipsychotic Agents; Aripiprazole; Body Mass Index; China; Delayed-Action Preparations; Diagnostic and Statistical Manual of Mental Disorders; Female; Follow-Up Studies; Humans; Hyperglycemia; Hyperlipidemias; Isoxazoles; Male; Metabolic Diseases; Paliperidone Palmitate; Piperazines; Psychiatric Status Rating Scales; Pyrimidines; Quinolones; Schizophrenia; Thiazoles; Weight Gain; Young Adult

2012

Other Studies

6 other study(ies) available for ziprasidone and isoxazoles

ArticleYear
Identification of the major human liver cytochrome P450 isoform(s) responsible for the formation of the primary metabolites of ziprasidone and prediction of possible drug interactions.
    British journal of clinical pharmacology, 2000, Volume: 49 Suppl 1

    Topics: Antipsychotic Agents; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Isoenzymes; Isoxazoles; Liver; Microsomes, Liver; Paliperidone Palmitate; Piperazines; Pyrimidines; Risperidone; Sulfones; Sulfoxides; Thiazoles

2000
alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs.
    European journal of pharmacology, 2003, Feb-21, Volume: 462, Issue:1-3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Brimonidine Tartrate; Chlorpromazine; CHO Cells; Clozapine; Cricetinae; Cyclic AMP; Dibenzothiazepines; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Gene Expression; Haloperidol; Humans; Isoxazoles; Norepinephrine; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Quinolones; Quinoxalines; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Risperidone; Thiazoles; Transfection; Yohimbine

2003
Sensitive liquid chromatography/tandem mass spectrometry method for the simultaneous determination of olanzapine, risperidone, 9-hydroxyrisperidone, clozapine, haloperidol and ziprasidone in rat brain tissue.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Oct-15, Volume: 858, Issue:1-2

    Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chromatography, Liquid; Clozapine; Haloperidol; Isoxazoles; Male; Olanzapine; Paliperidone Palmitate; Piperazines; Pyrimidines; Rats; Reproducibility of Results; Risperidone; Tandem Mass Spectrometry; Thiazoles

2007
Effects of quetiapine, risperidone, 9-hydroxyrisperidone and ziprasidone on the survival of human neuronal and immune cells in vitro.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:3

    Topics: Adenosine Triphosphate; Antipsychotic Agents; Cell Line; Cell Survival; Dibenzothiazepines; Dose-Response Relationship, Drug; Energy Metabolism; Humans; Isoxazoles; Monocytes; Neurons; Paliperidone Palmitate; Piperazines; Pyrimidines; Quetiapine Fumarate; Risperidone; Thiazoles

2010
Bitter pills for drug companies.
    BMJ (Clinical research ed.), 2010, Sep-17, Volume: 341

    Topics: Acetamides; Drug Approval; Drug Industry; Fraud; gamma-Aminobutyric Acid; Isoxazoles; Linezolid; Motivation; Off-Label Use; Oxazolidinones; Piperazines; Pregabalin; Sulfonamides; Thiazoles; United States

2010
Understanding responder neurobiology in schizophrenia using a quantitative systems pharmacology model: application to iloperidone.
    Journal of psychopharmacology (Oxford, England), 2015, Volume: 29, Issue:4

    Topics: Antipsychotic Agents; Computer Simulation; Genotype; Humans; Isoxazoles; Models, Biological; Molecular Targeted Therapy; Neurobiology; Pharmacogenetics; Piperazines; Piperidines; Schizophrenia; Thiazoles

2015