zingerone has been researched along with guaiacol in 161 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (4.35) | 18.7374 |
| 1990's | 10 (6.21) | 18.2507 |
| 2000's | 16 (9.94) | 29.6817 |
| 2010's | 83 (51.55) | 24.3611 |
| 2020's | 45 (27.95) | 2.80 |
| Authors | Studies |
|---|---|
| Monge, P; Scheline, R; Solheim, E | 1 |
| Castle, NA | 1 |
| Erhun, WO; Kolawole, DO; Oloke, JK | 1 |
| Amonkar, AJ; Bhide, SV; Nagabhushan, M | 1 |
| Iwai, K; Kawada, T; Sakabe, S; Watanabe, T; Yamamoto, M | 1 |
| Burks, TF; Miller, MJ; Miller, MS; Sipes, IG | 1 |
| Jancsó-Gabor, A | 1 |
| Aeschbach, R; Aruoma, OI; Butler, J; Halliwell, B; Löliger, J; Murcia, A; Scott, BC | 1 |
| Fernando Larrondo, L; Larraín, J; Lobos, S; Urzúa, U; Vicuña, R | 1 |
| Green, BG | 2 |
| Prescott, J; Stevenson, RJ | 2 |
| Liu, L; Simon, SA | 2 |
| Lee, E; Surh, YJ | 1 |
| Agarwal, M; Dhingra, S; Khambay, BP; Walia, S | 1 |
| MERZ, KW; PFAFFLE, H | 1 |
| Green, BG; Hayes, JE | 1 |
| Bányász, T; Fülöp, L; Magyar, J; Nánási, PP; Szentandrássy, N; Varró, A | 1 |
| Campbell, BC; Chan, KL; Kim, JH; Mahoney, NE; Molyneux, RJ | 1 |
| Higashio, C; Kabuto, H; Kohno, M; Nishizawa, M; Shishibori, T; Tada, M | 1 |
| Chung, HY; Jeong, JC; Kim, JY; Shin, SG | 1 |
| Campbell, BC; Chan, KL; Kim, JH; Mahoney, N; Molyneux, RJ | 1 |
| Campbell, BC; Chan, KL; Kim, JH; Mahoney, N; May, GS | 1 |
| Shukla, Y; Singh, M | 1 |
| Hamada, H; Harada, T; Nakajima, N; Shimoda, K | 1 |
| Affeltranger, MA; Balaban, CD; McBurney, DH | 1 |
| Chen, JC; Ho, TY; Hsiang, CY; Huang, LJ; Kuo, SC; Wu, SL | 1 |
| Ahn, IS; Hwang, S; Lee, CH; Park, K | 1 |
| Asami, E; Han, LK; Li, W; Morimoto, C; Okuda, H; Saito, M; Zheng, YN | 1 |
| Wang, LY; Wang, ZT; Zhang, CF; Zhang, M | 1 |
| Anton, S; Choi, JS; Chung, HY; Chung, JH; Chung, SW; Kim, DH; Kim, MK; Park, KY; Rhee, SH; Seo, AY; Yokozawa, T; Yu, BP | 1 |
| Choi, JS; Chung, HS; Chung, HY; Chung, SW; Ha, YM; Kim, DH; Kim, JM; Kim, JY; Kim, MK; Kim, YH; Kim, YJ; Lee, EK; No, JK; Park, KY; Rhee, SH; Yokozawa, T; Yu, BP | 1 |
| Morimoto, Y; Shibata, Y | 1 |
| Rao, BN; Rao, BS | 1 |
| Hirayama, H; Iwami, M; Shiina, T; Shima, T; Shimizu, Y; Takewaki, T | 1 |
| Aithal, BK; Archana, PR; Rao, BN; Rao, BS | 1 |
| Hirayama, H; Iwami, M; Shiina, T; Shimizu, Y | 1 |
| Kabuto, H; Yamanushi, TT | 1 |
| Hiratake, J; Koeduka, T; Mano, J; Suzuki, S; Watanabe, B; Yazaki, K | 1 |
| Baliga, MS; Bhat, HP; D'Souza, JJ; Haniadka, R; Pallaty, PL; Pereira, MM; Popuri, S | 1 |
| Chang, YP; Chiang, CM; Hsieh, SL; Lian, JL; Liu, CH; Wu, CC | 1 |
| Ho, TY; Hsiang, CY; Huang, HC; Li, CC; Lo, HY; Wu, SL | 1 |
| Abd-Alrahman, SH; Al-Daghri, NM; Alkharfy, KM; Alokail, MS; Amer, OE; Krishnaswamy, S; Mohammed, AK; Yakout, SM | 1 |
| Bettadaiah, BK; Manjunatha, JR; Negi, PS; Srinivas, P | 1 |
| Fujita, T; Kumamoto, E; Mizuta, K; Nishikubo, Y; Tomohiro, D | 1 |
| Bubacco, L; Dedola, S; Delogu, G; Dettori, MA; Fabbri, D; Hussain, R; Mammi, S; Marchiani, A; Ruzza, P; Sanna, D; Serra, PA; Siligardi, G; Tessari, I | 1 |
| Fujita, T; Jiang, CY; Kumamoto, E; Yue, HY | 1 |
| Chhibber, S; Harjai, K; Kumar, L | 3 |
| Nalini, N; Sudha, M; Vinothkumar, R | 1 |
| Belcher, JD; Burhop, K; Chen, C; Nguyen, J; Tran, P; Vercellotti, GM; Young, M | 1 |
| Jayasree, PR; Manish Kumar, PR; Narayanan, N; Rabindran, R; Rajan, I | 1 |
| Ahmed, ME; Islam, F; Javed, H; Khan, A; Safhi, MM; Shrivastava, P; Tabassum, R; Vaibhav, K | 1 |
| Annamalai, AR; Banji, D; Banji, OJ; Kranthi Kumar, Ch; Pavani, B | 1 |
| Ding, Y; Ren, Y; Soromou, LW; Sun, S; Wei, M; Xie, X; Zhong, W; Zhou, X | 1 |
| Clarke, AR; Hayes, RA; Kumaran, N | 1 |
| Clarke, AR; Kumaran, N; Mangalam, KP; Prentis, PJ; Schutze, MK | 1 |
| Hemalatha, KL; Prince, PS | 1 |
| Hemalatha, KL; Stanely Mainzen Prince, P | 4 |
| Di Liberto, MG; Suárez, AG; Svetaz, LA; Zacchino, SA; Zanardi, MM | 1 |
| Chhibber, S; Harjai, K; Kumar, L; Kumar, M; Kumar, R | 1 |
| Cheng, HM; Chou, PC; Ho, TY; Hsiang, CY; Lee, YC; Li, CC; Lo, HY | 1 |
| Afzal, I; Ahmad, B; Amin, I; Arif, A; Bhat, SA; Bilal, S; Hussain, I; Mir, Mu; Rasool, S; Rehman, MU | 1 |
| Bae, WY; Choi, JS; Jeong, JW; Park, C | 1 |
| Bak, J; Cheong, KO; Chung, HY; Je, NK; Kim, KW; Lee, C; Moon, JO; Shin, DS; Yoon, S | 1 |
| Ding, H; Fan, HJ; Hou, SK; Li, H; Lv, Q; Song, J | 1 |
| Han, Y; Hong, Y; Li, Y; Wang, Y; Xia, L | 1 |
| Haratake, A; Matsunaga, K; Nagata-Akaho, N; Setoguchi, S; Takata, J; Watase, D | 1 |
| Jesudoss, VA; Muniandy Narayanan, J | 1 |
| Alahdal, AM; Azhar, A; Banjar, ZM; El-Bassossy, HM; Elberry, AA; Ghareib, SA; Watson, ML | 1 |
| Bae, WY; Choi, JS; Jeong, JW; Kim, JE; Park, C | 1 |
| Arivalagan, S; Mani, V; Namasivayam, N; Siddique, AI | 1 |
| Budprom, P; Chokchaitaweesuk, C; Chomdej, S; Kongdang, P; Nganvongpanit, K; Ongchai, S; Ruangsuriya, J; Sirikaew, N; Viriyakhasem, N | 1 |
| Ham, J; Jeon, Y; Kim, T; Kim, TJ; Kim, YJ; Ko, H; Lim, WC; Park, YN | 1 |
| Bae, JS; Kim, MA; Ku, SK; Lee, W | 1 |
| Arivalagan, S; Islam Siddique, A; Mani, V; Namasivayam, N | 1 |
| Bernauer, U | 1 |
| Bae, JS; Ku, SK; Lee, T; Min, G | 1 |
| Bae, JS; Ku, SK; Lee, W | 1 |
| Arita, K; Enoki, S; Hattori, T; Ishiai, S; Mikami, M; Nagasaka, S; Suzuki, S; Tanaka, S | 1 |
| Abdel Aziz, AAA; Abozaid, OAR; Farrag, MA; Moawed, FSM | 1 |
| Cho, JY; Lee, J; Lee, KW; Oh, SW; Shin, SW | 1 |
| Al-Thubiani, WS; Azhar, AS; Banjar, ZM; El-Bassossy, HM; Elberry, AA; Ghareib, SA; Mujallid, MI; Watson, ML | 1 |
| Bae, JS; Hwang, MH; Lee, W; Lee, Y | 1 |
| Bao, Y; Cui, Y; Hua, Q; Liu, Y; Shi, Y; Wang, S | 1 |
| Ahmad, B; Ahmad, SB; Bhat, SA; Ganaie, MA; Madkhali, H; Majid, S; Rashid, SM; Rasool, S; Rehman, MU; Shakeel, S | 1 |
| Caglayan, C; Kandemir, FM; Kaygusuzoglu, E; Kılınc, MA; Kucukler, S; Saglam, YS; Yıldırım, S | 1 |
| Safhi, MM | 1 |
| Kim, BJ; Kim, HJ; Kim, I; Kim, JN; Kim, YT | 1 |
| Anees, LM; Ibrahim, DM; Soliman, AF | 1 |
| Alvim, ID; Hubinger, MD; Oriani, VB; Pastore, GM; Paulino, BN; Procópio, FR | 1 |
| Alibakhshi, T; Khodayar, MJ; Khorsandi, L; Rashno, M; Zeidooni, L | 1 |
| Caglayan, C; Dortbudak, MB; Kandemir, FM; Kucukler, S; Mahamadu, A; Yildirim, S | 1 |
| Bae, JS; Ku, SK; Lee, BS; Lee, C; Yang, S | 1 |
| Bae, WY; Choi, JS; Jeong, JW; Kim, JE; Nam, S; Park, A; Ryu, J | 1 |
| Hsieh, S; Hsieh, SL; Huang, ST; Kung, ML; Lin, PY; Tai, MH; Wu, CC; Wu, WJ; Yeh, BW | 1 |
| Al Saeedan, A; Ganaie, MA; Jan, BL; Khatlani, T; Madhkali, H; Rehman, MU; Sheikh, IA; Wani, K | 1 |
| Brinon, J; Cazeres, S; Mayer, DG; Mille, C; Royer, JE | 1 |
| Musa, AE; Shabeeb, D | 1 |
| Balagangadharan, K; Paarkavi, U; Pooja, V; Selvamurugan, N; Srinaath, N; Trishla, A | 1 |
| George, K; Malathi, R; Thomas, NS | 1 |
| Caglayan, C; Eser, G; Kandemir, FM; Kucukler, S; Yildirim, S | 1 |
| Khorsandi, L; Nejad-Dehbashi, F; Rafiee, Z | 1 |
| Cai, ZL; Deng, W; Duan, MX; Liu, C; Tang, QZ; Wu, QQ; Xie, QW; Xie, SY; Yuan, Y | 1 |
| Alkarbi, ZA; Alshahrani, S; Anwer, T; Firoz Alam, M; Hassan Najmi, A; Khan, G; Siddiqui, R | 1 |
| Çağlayan, C; Demir, Y; Gulçin, İ; Kandemir, FM; Küçükler, S; Taslimi, P | 1 |
| Bojanowski, K; Chaudhuri, RK; Swindell, WR | 1 |
| Gan, H; Mohan, SK; Veeraraghavan, VP; Xie, X; Zhang, Y; Zheng, L; Zhou, Q | 1 |
| Badawy, MMM; Mohamed, HE | 1 |
| Brash, D; Chaudhuri, RK; Meyer, T; Premi, S | 1 |
| Cui, J; Dong, Y; Duan, Y; Fan, S; Li, D; Li, H; Li, Y; Wang, M; Wu, J | 1 |
| Krishna Mohan, S; Lu, W; Su, P; Veeraraghavan, VP | 1 |
| Hanssen, BL; Jamie, IM; Jamie, JF; Park, SJ; Royer, JE; Taylor, PW | 1 |
| Li, Y; Mou, R; Song, Y; Yang, T | 1 |
| Burney, W; Crawford, R; Dhaliwal, S; Haas, K; K Sivamani, R; Pourang, A; Rybak, I; Sandhu, S | 1 |
| Arslanbas, E; Ekici, M; Gungor, H; Kara, H; Onder Karayigit, M; Turgut, NH | 1 |
| Kim, ASY; Lee, CH; Lee, DH; Lee, SM | 1 |
| Erlwanger, KH; Lembede, BW; Muhammad, N | 2 |
| Mayer, DG; Royer, JE; Tan, KH | 1 |
| Ahmad, P; Ahmad, SB; Amin, I; Arafah, A; Ganaie, SA; Hussain, I; Mir, BA; Mir, MUR; Muzamil, S; Rehman, MU; Shanaz, S | 1 |
| Cameron, DNS; Cheesman, J; Faveri, SG; Hanssen, BL; Jamie, IM; Park, SJ; Taylor, PW | 1 |
| Ağgül, AG; Cellat, M; Güvenç, M; Kırbaş, A; Kuzu, M; Türk, E; Uyar, A | 1 |
| Ayna, A; Caglayan, C; Darendelioğlu, E; Kandemir, FM; Kucukler, S; Yıldırım, S | 1 |
| Fang, H; Liu, M; Qian, S; Zheng, L | 1 |
| Clarke, AR; Wee, SL | 1 |
| Bose, SK; Chhibber, S; Harjai, K; Sharma, K | 1 |
| Beaudry, F; Ben Salem, J; Nkambeu, B | 1 |
| Ahmad, A; Ahmad, P; Alnemer, O; Kazi, M; Raish, M; Rao, PGM; Rehman, MU; Wali, AF | 1 |
| Chhibber, S; Harjai, K; Kaur, P; Nosran, A; Randhawa, V; Singh, V | 1 |
| Hassan, ZM; Jafarzadeh, A; Kazemi, M; Khorramdelazad, H; Nemati, M; Oladpour, O; Rezayati, MT; Taghipour, F | 1 |
| Chen, P; Wu, D; Yang, B; Zheng, P | 1 |
| Adu-Frimpong, M; Bao, R; Cao, X; Wang, QL; Wang, YP; Wei, CM; Weng, W; Xu, XM; Yu, JN; Zhu, Q | 1 |
| Hua, S; Li, D; Liu, H; Luo, J; Peng, L; Song, L; Wang, C; Zhu, Y | 1 |
| Chandla, S; Harjai, K; Shukla, G | 2 |
| Ahmad, SB; Bashir, N; Bhat, RR; Elossaily, GM; Ibrahim, MA; Kazi, M; Mir, MUR; Muzamil, S; Rehman, MU; Shazly, GA; Sherif, AY | 1 |
| Geng, X; Liu, H; Sun, J; Wang, J; Yuwen, Q; Zhang, S; Zhang, X | 1 |
| Ge, Z; Wang, Q; Xu, X; Yu, J; Yusif, M; Zhu, Q | 1 |
| Kawee-Ai, A; Sida, S; Utama-Ang, N; Wanachantararak, P | 1 |
| Bojanowski, K; Chaudhuri, RK; Quijas, G; Randhawa, M; Swindell, WR | 1 |
| Cömertpay, S; Delibaş, M; Gül, A; Tekin Turhan, MS | 1 |
| Contestabile, V; Mazzon, E; Schepici, G; Valeri, A | 1 |
| Fang, J; Jiang, R; Xu, P; Zhu, H | 1 |
| Bai, X; Jie, J; Li, D; Liu, H; Luo, J; Peng, L; Wang, D; Zhu, Y | 1 |
| Cui, Y; Huang, J; Liu, S; Liu, Y; Zhang, Z; Zhou, Y; Zhu, Z | 1 |
| Huang, CW; Lai, MC; Wu, SN | 1 |
| Dayati, P; Moradi, A; Shahidi, M | 1 |
| Mohammed, HM | 1 |
| Jang, WG; Kim, AR; Lim, YJ | 1 |
| Akhtar, A; Pilkhwal Sah, S; Sharma, PK; Upadhyaya, K | 1 |
| Samy, W | 1 |
| Dandago, MA; Elysé, FKR; Foncha, AC; Haruna, SA; Ivane, NMA; Pride, N; Richard, E | 1 |
| Carta, P; Caval, M; Dallocchio, R; Dessì, A; Dettori, MA; Fabbri, D; Marceddu, S; Rocchitta, G; Serra, PA | 1 |
| Chen, J; Chen, X; Miao, C; Ni, S; Sun, R; Yin, G; Zhang, Z | 1 |
6 review(s) available for zingerone and guaiacol
| Article | Year |
|---|---|
Cancer preventive properties of ginger: a brief review.
Topics: Animals; Anticarcinogenic Agents; Breast Neoplasms; Catechols; Colonic Neoplasms; Fatty Alcohols; Gastrointestinal Neoplasms; Guaiacol; Humans; Ketones; Oils, Volatile; Skin Neoplasms; Tumor Cells, Cultured; Zingiber officinale | 2007 |
Update on the chemopreventive effects of ginger and its phytochemicals.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antiemetics; Antioxidants; Apoptosis; Carcinogens; Catechols; Cell Cycle; Cell Line, Tumor; Drug Evaluation, Preclinical; Fatty Alcohols; Guaiacol; Humans; Lipid Peroxidation; Neoplasms; Plant Extracts; Protein Carbonylation; Rhizome; Signal Transduction; Spices; Transcription Factors; Zingiber officinale | 2011 |
A Review on Pharmacological Properties of Zingerone (4-(4-Hydroxy-3-methoxyphenyl)-2-butanone).
Topics: Animals; Anti-Inflammatory Agents; Antidiarrheals; Antiemetics; Antineoplastic Agents; Antioxidants; Guaiacol; Humans; Lipolysis; Plant Extracts; Radiation-Protective Agents; Zingiber officinale | 2015 |
Opinion of the scientific committee on consumer safety (SCCS) - Final version of the opinion on Ethylzingerone - 'Hydroxyethoxyphenyl Butanone' (HEPB) - Cosmetics Europe No P98 - in cosmetic products.
Topics: Advisory Committees; Animals; Attitude; Butanones; Consumer Product Safety; Cosmetics; Drug Evaluation, Preclinical; Europe; Guaiacol; Humans | 2017 |
Radiation-Induced Heart Diseases: Protective Effects of Natural Products.
Topics: Biological Products; Caffeic Acids; Curcumin; Drug Combinations; Drugs, Chinese Herbal; Guaiacol; Heart Diseases; Hesperidin; Humans; Melatonin; Phenylethyl Alcohol; Protective Factors; Radiation Injuries; Selenium; Vitis | 2019 |
Ginger, a Possible Candidate for the Treatment of Dementias?
Topics: Catechols; Dementia; Drug Discovery; Fatty Alcohols; Guaiacol; Humans; Ketones; Models, Molecular; Plant Extracts; Protective Agents; Sesquiterpenes; Structure-Activity Relationship; Zingiber officinale | 2021 |
3 trial(s) available for zingerone and guaiacol
| Article | Year |
|---|---|
Psychophysical responses to single and multiple presentations of the oral irritant zingerone: relationship to frequency of chili consumption.
Topics: Adult; Feeding Behavior; Female; Food; Guaiacol; Humans; Irritants; Kinetics; Male; Spices | 1996 |
Rapid recovery from capsaicin desensitization during recurrent stimulation.
Topics: Administration, Oral; Adult; Alkaloids; Analysis of Variance; Benzodioxoles; Capsaicin; Citric Acid; Depression, Chemical; Dose-Response Relationship, Drug; Female; Guaiacol; Humans; Irritants; Logistic Models; Male; Piperidines; Polyunsaturated Alkamides; Reference Values; Stimulation, Chemical; Time Factors; Tongue | 1996 |
Randomized double-blind vehicle controlled study of the effects of topical acetyl zingerone on photoaging.
Topics: Adult; Double-Blind Method; Guaiacol; Humans; Hyperpigmentation; Middle Aged; Skin Aging; Treatment Outcome | 2021 |
152 other study(ies) available for zingerone and guaiacol
| Article | Year |
|---|---|
The metabolism of zingerone, a pungent principle of ginger.
Topics: Animals; Bile; Butanones; Cecum; Chromatography, Gas; Guaiacol; Male; Mass Spectrometry; Rats | 1976 |
Differential inhibition of potassium currents in rat ventricular myocytes by capsaicin.
Topics: Action Potentials; Animals; Capsaicin; Diterpenes; Dose-Response Relationship, Drug; Guaiacol; Muscles; Potassium; Rats; Rats, Sprague-Dawley; Time Factors | 1992 |
Antimicrobial effectiveness of six paradols. 1: A structure-activity relationship study.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Guaiacol; Mitosporic Fungi; Plants, Medicinal; Proteus vulgaris; Pseudomonas aeruginosa; Staphylococcus aureus; Structure-Activity Relationship; Trichophyton | 1989 |
Mutagenicity of gingerol and shogaol and antimutagenicity of zingerone in Salmonella/microsome assay.
Topics: Animals; Catechols; Fatty Alcohols; Guaiacol; Male; Mutagenicity Tests; Mutagens; Rats; Rats, Inbred Strains; Salmonella typhimurium; Structure-Activity Relationship | 1987 |
Some pungent principles of spices cause the adrenal medulla to secrete catecholamine in anesthetized rats.
Topics: Adrenal Medulla; Alkaloids; Animals; Benzodioxoles; Capsaicin; Catecholamines; Condiments; Epinephrine; Guaiacol; Intestinal Absorption; Kinetics; Male; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Inbred Strains | 1988 |
A simple, sensitive method for detecting early peripheral nerve dysfunction in the rat following acrylamide treatment.
Topics: Acrylamide; Acrylamides; Animals; Cholinergic Fibers; Guaiacol; Male; Neostigmine; Peripheral Nervous System Diseases; Rats; Rats, Inbred Strains; Synaptic Transmission | 1984 |
Anaesthesia-like condition and/or potentiation of hexobarbital sleep produced by pungent agents in normal and capsaicin-desensitized rats.
Topics: Anesthesia; Animals; Body Temperature; Body Temperature Regulation; Butanones; Capsaicin; Desensitization, Immunologic; Drug Synergism; Fatty Acids, Unsaturated; Female; Guaiacol; Hexobarbital; Hypothermia; Ketones; Male; Preoptic Area; Rats; Sleep | 1980 |
Antioxidant actions of thymol, carvacrol, 6-gingerol, zingerone and hydroxytyrosol.
Topics: Antioxidants; Ascorbic Acid; Bleomycin; Catechols; Cymenes; Deoxyribose; DNA Damage; Fatty Alcohols; Ferric Compounds; Food Preservation; Guaiacol; Hydroxyl Radical; Lipid Peroxidation; Liposomes; Monoterpenes; Phenylethyl Alcohol; Pulse Radiolysis; Terpenes; Thymol | 1994 |
Oxidation reactions catalyzed by manganese peroxidase isoenzymes from Ceriporiopsis subvermispora.
Topics: Basidiomycota; Benzothiazoles; Dianisidine; Electrophoresis, Polyacrylamide Gel; Guaiacol; Isoelectric Point; Isoenzymes; Manganese; Oxalates; Oxalic Acid; Oxidation-Reduction; Peroxidases; Pyrones; Sulfonic Acids | 1995 |
Evidence that removal of capsaicin accelerates desensitization on the tongue.
Topics: Capsaicin; Guaiacol; Humans; Irritants; Nerve Fibers; Time Factors; Tongue | 1993 |
Similarities and differences in the currents activated by capsaicin, piperine, and zingerone in rat trigeminal ganglion cells.
Topics: Alkaloids; Animals; Benzodioxoles; Biotransformation; Calcium; Capsaicin; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Guaiacol; Ion Channels; Neurons; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Rats; Rats, Sprague-Dawley; Receptors, Drug; Structure-Activity Relationship; Tachyphylaxis; Trigeminal Ganglion | 1996 |
Desensitization to oral zingerone irritation: effects of stimulus parameters.
Topics: Adult; Capsaicin; Chemoreceptor Cells; Dose-Response Relationship, Drug; Female; Guaiacol; Humans; Male; Sensitivity and Specificity | 1996 |
The influence of removing extracellular Ca2+ in the desensitization responses to capsaicin, zingerone and olvanil in rat trigeminal ganglion neurons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Capsaicin; Extracellular Space; Guaiacol; Neurons, Afferent; Pain; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Tachyphylaxis; Taste; Trigeminal Ganglion | 1998 |
Induction of apoptosis in HL-60 cells by pungent vanilloids, [6]-gingerol and [6]-paradol.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Catechols; Fatty Alcohols; Guaiacol; HL-60 Cells; Humans | 1998 |
Insect growth inhibition, antifeedant and antifungal activity of compounds isolated/derived from Zingiber officinale Roscoe (ginger) rhizomes.
Topics: Animals; Antifungal Agents; Catechols; Fatty Alcohols; Feeding Behavior; Guaiacol; Insect Control; Insecticides; Larva; Lepidoptera; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mutagens; Plants, Medicinal; Styrenes; Zingiber officinale | 2001 |
[On o-vanillylacetone and its hydrogenation products with a contribution to hydrogenating amination of ketones].
Topics: Acetone; Amination; Guaiacol; Hydrogenation; Ketones | 1955 |
Individual differences in perception of bitterness from capsaicin, piperine and zingerone.
Topics: Adolescent; Adult; Alkaloids; Benzodioxoles; Capsaicin; Female; Guaiacol; Humans; Male; Middle Aged; Perception; Piperidines; Polyunsaturated Alkamides; Receptors, Cell Surface; Taste; Taste Buds | 2004 |
Effects of terpenoid phenol derivatives on calcium current in canine and human ventricular cardiomyocytes.
Topics: Animals; Calcium Channels; Cell Separation; Cymenes; Dogs; Electrophysiology; Eugenol; Guaiacol; Heart Ventricles; Humans; In Vitro Techniques; Kinetics; Membrane Potentials; Monoterpenes; Myocytes, Cardiac; Patch-Clamp Techniques; Phenols; Terpenes | 2004 |
Identification of phenolics for control of Aspergillus flavus using Saccharomyces cerevisiae in a model target-gene bioassay.
Topics: Aflatoxins; Aspergillus flavus; Benzaldehydes; Cinnamates; Drug Synergism; Fungicides, Industrial; Guaiacol; Phenols; Saccharomyces cerevisiae | 2004 |
Zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] prevents 6-hydroxydopamine-induced dopamine depression in mouse striatum and increases superoxide scavenging activity in serum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catalase; Dopamine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Glutathione Peroxidase; Guaiacol; Homovanillic Acid; Hydroxyl Radical; Male; Mice; Mice, Inbred ICR; Neostriatum; Nerve Tissue Proteins; Oxidopamine; Superoxides; Sympatholytics | 2005 |
Zingerone as an antioxidant against peroxynitrite.
Topics: Antioxidants; Free Radical Scavengers; Guaiacol; Peroxynitrous Acid; Serum Albumin, Bovine; Tyrosine | 2005 |
Controlling food-contaminating fungi by targeting their antioxidative stress-response system with natural phenolic compounds.
Topics: Antifungal Agents; Antioxidants; Aspergillus flavus; Aspergillus niger; Benzaldehydes; Carboxin; Cinnamates; Drug Synergism; Food Contamination; Fungicides, Industrial; Gene Deletion; Guaiacol; Juglans; Microbial Sensitivity Tests; Mitochondria; Phenols; Saccharomyces cerevisiae; Superoxide Dismutase; Thymol | 2006 |
Targeting antioxidative signal transduction and stress response system: control of pathogenic Aspergillus with phenolics that inhibit mitochondrial function.
Topics: Antifungal Agents; Aspergillus; Aspergillus flavus; Aspergillus fumigatus; Dioxoles; Gene Expression; Guaiacol; Mitochondria; Mitogen-Activated Protein Kinases; Mycology; Oxidation-Reduction; Phenols; Pyrroles; Saccharomyces cerevisiae; Signal Transduction; Superoxide Dismutase | 2006 |
Biotransformation of raspberry ketone and zingerone by cultured cells of Phytolacca americana.
Topics: Biotransformation; Butanones; Cell Line; Cells, Cultured; Flavoring Agents; Guaiacol; Kinetics; Magnetic Resonance Spectroscopy; Phytolacca americana | 2007 |
Temporal interactions between oral irritants: piperine, zingerone, and capsaicin.
Topics: Administration, Oral; Alkaloids; Benzodioxoles; Capsaicin; Guaiacol; Humans; Irritants; Piperidines; Polyunsaturated Alkamides | 2007 |
Ginger and its bioactive component inhibit enterotoxigenic Escherichia coli heat-labile enterotoxin-induced diarrhea in mice.
Topics: Animals; Bacterial Toxins; Diarrhea; Enterotoxins; Escherichia coli Proteins; Female; G(M1) Ganglioside; Guaiacol; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Roots; Zingiber officinale | 2007 |
Manganese peroxidase-catalyzed oxidative degradation of vanillylacetone.
Topics: Catalysis; Chromatography, High Pressure Liquid; Guaiacol; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Peroxidases; Spectrophotometry, Infrared | 2008 |
[Effects of zingerone on fat storage in ovariectomized rats].
Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Female; Guaiacol; Lipid Metabolism; Lipolysis; Norepinephrine; Ovariectomy; Rats; Rats, Wistar; Sterol Esterase | 2008 |
Alkaloid and sesquiterpenes from the root tuber of Curcuma longa.
Topics: Alkaloids; Curcuma; Cyclohexanols; Guaiacol; Molecular Structure; Plant Tubers; Plants, Medicinal; Sesquiterpenes; Styrenes | 2008 |
Peroxisome proliferator-activated receptor activation by a short-term feeding of zingerone in aged rats.
Topics: Aging; Animals; Anti-Inflammatory Agents; Cell Line; DNA; Down-Regulation; Gene Expression; Guaiacol; Hepatocyte Nuclear Factor 4; Male; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Plant Extracts; Rats; Rats, Sprague-Dawley; Zingiber officinale | 2009 |
Modulation of age-related NF-kappaB activation by dietary zingerone via MAPK pathway.
Topics: Aging; Animals; Anti-Inflammatory Agents; Antioxidants; Blotting, Western; Caloric Restriction; Guaiacol; Humans; Inflammation; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred F344; Reactive Oxygen Species | 2010 |
Effects of various fragrant ingredients on desmopressin-induced fluid retention in mice.
Topics: Animals; Aromatherapy; Cyclohexenes; Deamino Arginine Vasopressin; Disease Models, Animal; Diuretics; Dose-Response Relationship, Drug; Edema; Furosemide; Guaiacol; Limonene; Male; Mice; Mice, Inbred Strains; Terpenes | 2010 |
Antagonistic effects of Zingerone, a phenolic alkanone against radiation-induced cytotoxicity, genotoxicity, apoptosis and oxidative stress in Chinese hamster lung fibroblast cells growing in vitro.
Topics: Alkanes; Animals; Antioxidants; Apoptosis; Cell Proliferation; Cells, Cultured; Cricetinae; Cricetulus; Cytoprotection; DNA Damage; Drug Evaluation, Preclinical; Fibroblasts; Guaiacol; Lung; Models, Biological; Oxidative Stress; Phenols; Radiation Injuries, Experimental | 2010 |
Inhibitory effects of zingerone, a pungent component of Zingiber officinale Roscoe, on colonic motility in rats.
Topics: Animals; Colon; Gastrointestinal Motility; Guaiacol; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Zingiber officinale | 2011 |
Protective effect of zingerone, a dietary compound against radiation induced genetic damage and apoptosis in human lymphocytes.
Topics: Acridine Orange; Apoptosis; Comet Assay; Diet; DNA Damage; DNA Fragmentation; Ethidium; Gamma Rays; Guaiacol; Humans; Intracellular Space; Lymphocytes; Micronucleus Tests; Reactive Oxygen Species | 2011 |
Intraluminal administration of zingerol, a non-pungent analogue of zingerone, inhibits colonic motility in rats.
Topics: Animals; Colon; Diarrhea; Drug Administration Routes; Gastrointestinal Motility; Guaiacol; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Oxidation-Reduction; Plant Extracts; Rats; Rats, Wistar; Zingiber officinale | 2011 |
Effects of zingerone [4-(4-hydroxy-3-methoxyphenyl)-2-butanone] and eugenol [2-methoxy-4-(2-propenyl)phenol] on the pathological progress in the 6-hydroxydopamine-induced Parkinson's disease mouse model.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Corpus Striatum; Disease Models, Animal; Dopamine; Eugenol; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Guaiacol; Levodopa; Male; Mice; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Superoxide Dismutase | 2011 |
Characterization of raspberry ketone/zingerone synthase, catalyzing the alpha, beta-hydrogenation of phenylbutenones in raspberry fruits.
Topics: Butanones; Catalysis; Fruit; Guaiacol; Hydrogenation; NADH, NADPH Oxidoreductases; Phenols; Plant Proteins; Rosaceae | 2011 |
Dietary administration of zingerone to enhance growth, non-specific immune response, and resistance to Vibrio alginolyticus in Pacific white shrimp (Litopenaeus vannamei) juveniles.
Topics: Adjuvants, Immunologic; Animals; Diet; Guaiacol; Immunity, Innate; Penaeidae; Vibrio alginolyticus | 2012 |
Ginger extract and zingerone ameliorated trinitrobenzene sulphonic acid-induced colitis in mice via modulation of nuclear factor-κB activity and interleukin-1β signalling pathway.
Topics: Animals; Colitis; Female; Guaiacol; Humans; Interleukin-1beta; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Signal Transduction; Trinitrobenzenesulfonic Acid; Zingiber officinale | 2013 |
Fenugreek extract as an inducer of cellular death via autophagy in human T lymphoma Jurkat cells.
Topics: Antineoplastic Agents, Phytogenic; Autophagy; Benzaldehydes; Catechols; Cell Line; Dose-Response Relationship, Drug; Eugenol; Fatty Alcohols; Guaiacol; Humans; Jurkat Cells; Leukemia, T-Cell; Lymphoma, T-Cell; Microtubule-Associated Proteins; Phytotherapy; Plant Extracts; Polycyclic Sesquiterpenes; Seeds; Sesquiterpenes; Transcription, Genetic; Trigonella; Up-Regulation; Vacuoles | 2012 |
Synthesis of quinoline derivatives of tetrahydrocurcumin and zingerone and evaluation of their antioxidant and antibacterial attributes.
Topics: Anti-Bacterial Agents; Antioxidants; Bacteria; Curcumin; Guaiacol; Quinolines | 2013 |
Inhibition by capsaicin and its related vanilloids of compound action potentials in frog sciatic nerves.
Topics: Action Potentials; Animals; Antipruritics; Benzaldehydes; Benzylamines; Capsaicin; Curcumin; Diterpenes; Eugenol; Female; Guaiacol; Male; Procaine; Ranidae; Sciatic Nerve; Structure-Activity Relationship; TRPV Cation Channels; Vanillic Acid | 2013 |
Small molecules interacting with α-synuclein: antiaggregating and cytoprotective properties.
Topics: Adrenal Gland Neoplasms; alpha-Synuclein; Alzheimer Disease; Animals; Antioxidants; Cell Line, Tumor; Curcumin; Cytoprotection; Guaiacol; Parkinson Disease; Pheochromocytoma; Rats; Styrenes | 2013 |
Zingerone enhances glutamatergic spontaneous excitatory transmission by activating TRPA1 but not TRPV1 channels in the adult rat substantia gelatinosa.
Topics: Animals; Excitatory Postsynaptic Potentials; Glutamic Acid; Guaiacol; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Neurons; Rats; Rats, Sprague-Dawley; Substantia Gelatinosa; Synaptic Transmission; TRPA1 Cation Channel; TRPC Cation Channels; TRPV Cation Channels | 2013 |
Zingerone inhibit biofilm formation and improve antibiofilm efficacy of ciprofloxacin against Pseudomonas aeruginosa PAO1.
Topics: Anti-Bacterial Agents; Biofilms; Cell Movement; Ciprofloxacin; Drug Resistance, Multiple; Guaiacol; Herb-Drug Interactions; Phytotherapy; Plant Extracts; Pseudomonas aeruginosa; Pseudomonas Infections; Zingiber officinale | 2013 |
Chemopreventive effect of zingerone against colon carcinogenesis induced by 1,2-dimethylhydrazine in rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogenesis; Carcinogens; Colonic Neoplasms; Guaiacol; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar | 2014 |
MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice.
Topics: Anemia, Sickle Cell; Animals; Carbon Monoxide; Disease Models, Animal; Female; Guaiacol; Heme Oxygenase-1; Hemin; Hemoglobins; Humans; Inflammation; Male; Maleimides; Membrane Proteins; Mice; Mice, Transgenic; Microcirculation; NF-E2-Related Factor 2; NF-kappa B; Polyethylene Glycols; Vasculitis | 2013 |
Zingerone protects against stannous chloride-induced and hydrogen peroxide-induced oxidative DNA damage in vitro.
Topics: Antioxidants; DNA Damage; Guaiacol; Hydrogen Peroxide; Physarum polycephalum; Reactive Oxygen Species; Tin Compounds | 2013 |
Delayed administration of zingerone mitigates the behavioral and histological alteration via repression of oxidative stress and intrinsic programmed cell death in focal transient ischemic rats.
Topics: Animals; Apoptosis; Behavior, Animal; Brain Ischemia; Enzyme-Linked Immunosorbent Assay; Guaiacol; Male; Oxidative Stress; Rats; Rats, Wistar | 2013 |
Zingerone regulates intestinal transit, attenuates behavioral and oxidative perturbations in irritable bowel disorder in rats.
Topics: Animals; Body Weight; Colon; Corticosterone; Drug Evaluation, Preclinical; Gastrointestinal Transit; Guaiacol; Irritable Bowel Syndrome; Male; Maze Learning; Oxidative Stress; Phytotherapy; Plant Extracts; Random Allocation; Rats, Wistar; Zingiber officinale | 2014 |
Zingerone attenuates lipopolysaccharide-induced acute lung injury in mice.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cell Count; Cell Line; Guaiacol; I-kappa B Proteins; Interleukin-6; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-kappa B; NF-KappaB Inhibitor alpha; Peroxidase; Tumor Necrosis Factor-alpha | 2014 |
Cuelure but not zingerone make the sex pheromone of male Bactrocera tryoni (Tephritidae: Diptera) more attractive to females.
Topics: Animals; Butanones; Female; Guaiacol; Male; Pheromones; Sex Attractants; Tephritidae | 2014 |
Sexual selection in true fruit flies (Diptera: Tephritidae): transcriptome and experimental evidences for phytochemicals increasing male competitive ability.
Topics: Animals; Diet; Female; Guaiacol; Male; Sequence Analysis, RNA; Sex Attractants; Sexual Behavior, Animal; Tephritidae; Transcriptome | 2014 |
Zingerone suppresses liver inflammation induced by antibiotic mediated endotoxemia through down regulating hepatic mRNA expression of inflammatory markers in Pseudomonas aeruginosa peritonitis mouse model.
Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Endotoxemia; Endotoxins; Gene Expression Regulation; Guaiacol; Humans; Inflammation; Liver; Mice; Peritonitis; Pseudomonas aeruginosa; RNA, Messenger | 2014 |
Preventive effects of zingerone on altered lipid peroxides and nonenzymatic antioxidants in the circulation of isoproterenol-induced myocardial infarcted rats.
Topics: Animals; Antioxidants; Cardiotonic Agents; Guaiacol; Isoproterenol; Lipid Peroxidation; Male; Myocardial Infarction; Rats | 2015 |
Structural alterations in Pseudomonas aeruginosa by zingerone contribute to enhanced susceptibility to antibiotics, serum and phagocytes.
Topics: Animals; Anti-Bacterial Agents; Chemokine CXCL2; Chromatography, Liquid; Drug Resistance, Bacterial; Female; Guaiacol; Hydrophobic and Hydrophilic Interactions; Macrophages; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Phagocytosis; Pseudomonas aeruginosa; Pseudomonas Infections; Tumor Necrosis Factor-alpha | 2014 |
A biochemical and 2, 3, 5-triphenyl tetrazolium chloride staining study on the preventive effects of zingerone (vanillyl acetone) in experimentally induced myocardial infarcted rats.
Topics: Adenosine Triphosphatases; Animals; Biomarkers; Coloring Agents; Disease Models, Animal; Electrocardiography; Free Radical Scavengers; Guaiacol; Heart Ventricles; Hypertrophy, Left Ventricular; Isoproterenol; Male; Myocardial Infarction; Myoglobin; Phytochemicals; Rats, Wistar; Tachycardia; Tetrazolium Salts; Troponin T; Water-Electrolyte Imbalance | 2015 |
Efficient production of the flavoring agent zingerone and of both (R)- and (S)-zingerols via green fungal biocatalysis. Comparative antifungal activities between enantiomers.
Topics: Antifungal Agents; Biocatalysis; Biotransformation; Chromatography, High Pressure Liquid; Esters; Flavoring Agents; Fungi; Guaiacol; Microbial Sensitivity Tests; Proton Magnetic Resonance Spectroscopy; Stereoisomerism; Time Factors | 2014 |
Antihyperlipidaemic, antihypertrophic, and reducing effects of zingerone on experimentally induced myocardial infarcted rats.
Topics: Animals; Cardiomegaly; Guaiacol; Hyperlipidemias; Hypolipidemic Agents; Isoproterenol; Male; Myocardial Infarction; Protective Agents; Rats; Rats, Wistar | 2015 |
Zingerone silences quorum sensing and attenuates virulence of Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Biofilms; Guaiacol; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Pseudomonas aeruginosa; Quorum Sensing; Virulence | 2015 |
Ginger and Zingerone Ameliorate Lipopolysaccharide-Induced Acute Systemic Inflammation in Mice, Assessed by Nuclear Factor-κB Bioluminescent Imaging.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Female; Guaiacol; Humans; Inflammation; Interleukin-1beta; Lipopolysaccharides; Mice; NF-kappa B; Plant Extracts; Whole Body Imaging; Zingiber officinale | 2015 |
Zingerone activates VMAT2 during MPP(+) -induced Cell Death.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Cell Death; Corpus Striatum; Disease Models, Animal; Dopaminergic Neurons; Drug Interactions; Guaiacol; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Vesicular Monoamine Transport Proteins | 2015 |
Hepatoprotective effects of zingerone on carbon tetrachloride- and dimethylnitrosamine-induced liver injuries in rats.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Biomarkers; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytoprotection; Dimethylnitrosamine; Guaiacol; Hep G2 Cells; Hepatic Stellate Cells; Humans; Hydroxyproline; Inflammation Mediators; Lipid Peroxidation; Liver; Liver Cirrhosis, Experimental; Male; Mitogen-Activated Protein Kinases; Oxidative Stress; Rats, Sprague-Dawley; Signal Transduction | 2016 |
Zingerone ameliorates lipopolysaccharide-induced acute kidney injury by inhibiting Toll-like receptor 4 signaling pathway.
Topics: Acute Kidney Injury; Adaptor Proteins, Vesicular Transport; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Gene Expression Regulation; Guaiacol; Interleukin-1beta; Interleukin-6; Kidney; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; NF-E2-Related Factor 2; NF-kappa B; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2016 |
Chemical characterization and antioxidant activities comparison in fresh, dried, stir-frying and carbonized ginger.
Topics: Antioxidants; Catechols; Chromatography, High Pressure Liquid; Fatty Alcohols; Guaiacol; Mass Spectrometry; Plant Extracts; Zingiber officinale | 2016 |
Pharmacokinetics of Paradol Analogues Orally Administered to Rats.
Topics: Animals; Anti-Obesity Agents; Catechols; Fatty Alcohols; Guaiacol; Ketones; Male; Phenols; Rats; Rats, Sprague-Dawley | 2016 |
Hepatoprotective potential of zingerone against nonalcoholic fatty liver disease in rats fed with fructose-enriched diet.
Topics: Animals; Antioxidants; Dietary Sucrose; Fructose; Guaiacol; Lipid Metabolism; Liver; Male; Non-alcoholic Fatty Liver Disease; Protective Agents; Rats; Rats, Wistar; Treatment Outcome | 2016 |
Protective effect of zingerone on increased vascular contractility in diabetic rat aorta.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guaiacol; Male; Phenylephrine; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Vasodilator Agents | 2016 |
Zingerone suppresses angiogenesis via inhibition of matrix metalloproteinases during tumor development.
Topics: Animals; Cell Growth Processes; Disease Models, Animal; Guaiacol; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney Neoplasms; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic | 2016 |
Antioxidant and anti-inflammatory role of zingerone in ethanol-induced hepatotoxicity.
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Ethanol; Gene Expression Regulation; Guaiacol; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar | 2016 |
Anti-inflammatory and anti-thrombotic effects of zingerone in a rat model of myocardial infarction.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Disease Models, Animal; Fibrinolytic Agents; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Guaiacol; Interleukin-1beta; Interleukin-6; Isoproterenol; Male; Myocardial Infarction; Rats; Tumor Necrosis Factor-alpha | 2016 |
Suppression of Cartilage Degradation by Zingerone Involving the p38 and JNK MAPK Signaling Pathway.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Cartilage; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Glycosaminoglycans; Guaiacol; Humans; Interleukins; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Metacarpophalangeal Joint; Mitogen-Activated Protein Kinases; Osteoarthritis; p38 Mitogen-Activated Protein Kinases; RNA, Messenger; Swine; Tumor Necrosis Factor-alpha | 2017 |
Combined treatment with zingerone and its novel derivative synergistically inhibits TGF-β1 induced epithelial-mesenchymal transition, migration and invasion of human hepatocellular carcinoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Epithelial-Mesenchymal Transition; Guaiacol; Humans; Liver Neoplasms; Neoplasm Invasiveness; Transforming Growth Factor beta1 | 2017 |
Anti-factor Xa activities of zingerone with anti-platelet aggregation activity.
Topics: Animals; Factor Xa; Factor Xa Inhibitors; Guaiacol; Humans; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Zingiber officinale | 2017 |
Antihyperlipidemic and antiapoptotic potential of zingerone on alcohol induced hepatotoxicity in experimental rats.
Topics: Acyl Coenzyme A; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Disease Models, Animal; DNA Damage; Down-Regulation; Ethanol; Fatty Acids, Nonesterified; Guaiacol; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Liver Diseases, Alcoholic; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar | 2017 |
Suppressive effects of zingerone on TGFBIp-mediated septic responses.
Topics: Animals; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Guaiacol; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Sepsis; Transforming Growth Factor beta; Treatment Outcome | 2018 |
Zingerone reduces HMGB1-mediated septic responses and improves survival in septic mice.
Topics: Acetylation; Animals; Anti-Inflammatory Agents; Capillary Permeability; Cell Adhesion Molecules; Cells, Cultured; Coculture Techniques; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Endotoxins; Guaiacol; HMGB1 Protein; Human Umbilical Vein Endothelial Cells; Humans; Inflammation Mediators; Lung Injury; Male; Mice, Inbred C57BL; Neutrophils; Sepsis; Signal Transduction; Sirtuin 1; Time Factors; Transendothelial and Transepithelial Migration | 2017 |
Vanillylacetone up-regulates anthocyanin accumulation and expression of anthocyanin biosynthetic genes by inducing endogenous abscisic acid in grapevine tissues.
Topics: Abscisic Acid; Anthocyanins; Cell Culture Techniques; Fruit; Gene Expression Regulation, Plant; Guaiacol; Plant Proteins; Up-Regulation; Vitis | 2017 |
A molecular mechanism on the antiapoptotic effects of zingerone in isoproterenol induced myocardial infarcted rats.
Topics: Animals; Antioxidants; Apoptosis; Caspases; fas Receptor; Guaiacol; Isoproterenol; Male; Myocardial Infarction; Proto-Oncogene Proteins c-cbl; Rats | 2018 |
4-(4-Hydroxy-3-methoxyphenyl)-2-butanone modulates redox signal in gamma-irradiation-induced nephrotoxicity in rats.
Topics: Animals; Gamma Rays; Guaiacol; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar | 2017 |
Zingerone protects keratinocyte stem cells from UVB-induced damage.
Topics: Cell Cycle Checkpoints; Cell Death; Cells, Cultured; Cytokines; Gene Expression Regulation; Guaiacol; Humans; Inflammation; Keratinocytes; Ultraviolet Rays | 2018 |
Zingerone alleviates the delayed ventricular repolarization and AV conduction in diabetes: Effect on cardiac fibrosis and inflammation.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Electrocardiography; Fibrosis; Guaiacol; Heart Conduction System; Heart Ventricles; Inflammation; Lipids; Male; Oxidative Stress; Rats; Rats, Wistar; Weight Gain | 2017 |
Protective effects of zingerone on lipopolysaccharide-induced hepatic failure through the modulation of inflammatory pathways.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cytokines; Enzyme-Linked Immunosorbent Assay; Guaiacol; Injections, Intravenous; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myeloid Differentiation Factor 88; Protective Agents; Signal Transduction; Toll-Like Receptor 4 | 2018 |
Zingerone attenuates diabetic nephropathy through inhibition of nicotinamide adenine dinucleotide phosphate oxidase 4.
Topics: Animals; Cell Death; Collagen Type IV; Diabetic Nephropathies; Down-Regulation; Fibronectins; Glucose; Guaiacol; Humans; Inflammation; Kidney Tubules, Proximal; Lipids; Mice, Inbred C57BL; NADPH Oxidase 4; Oxidative Stress; Protective Agents; Up-Regulation | 2018 |
Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High-Fat; Gene Expression Regulation; Guaiacol; Inflammation; Kidney Function Tests; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Respiratory Burst; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |
Zingerone ameliorates cisplatin-induced ovarian and uterine toxicity via suppression of sex hormone imbalances, oxidative stress, inflammation and apoptosis in female wistar rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Apoptosis; Caspase 3; Catalase; Cisplatin; Cyclooxygenase 2; Deoxyguanosine; Estradiol; Female; Follicle Stimulating Hormone; Glutathione; Glutathione Peroxidase; Gonadal Steroid Hormones; Guaiacol; Inflammation; Interleukin-1beta; Interleukin-6; Malondialdehyde; NF-kappa B; Ovary; Oxidative Stress; Rats, Wistar; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Uterus | 2018 |
Nephroprotective Effect of Zingerone against CCl
Topics: Animals; Chemokine CCL4; Guaiacol; Kidney; Male; Mice | 2018 |
The Mechanism of Action of Zingerone in the Pacemaker Potentials of Interstitial Cells of Cajal Isolated from Murine Small Intestine.
Topics: Animals; Cells, Cultured; Cyclic GMP; Female; Gastrointestinal Motility; Guaiacol; Interstitial Cells of Cajal; Intestine, Small; Male; Membrane Potentials; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Nitric Oxide; Patch-Clamp Techniques; Potassium Channels | 2018 |
Cardioprotective effect of zingerone against oxidative stress, inflammation, and apoptosis induced by cisplatin or gamma radiation in rats.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Apoptosis; Cardiotonic Agents; Cisplatin; Creatine Kinase, MB Form; Cyclooxygenase 2; DNA Damage; Gamma Rays; Guaiacol; L-Lactate Dehydrogenase; Male; Malondialdehyde; Myocardium; Oxidative Stress; Rats | 2018 |
The influence of the storage temperature on the stability of lipid microparticles containing ginger oleoresin.
Topics: Catechols; Crystallization; Fatty Alcohols; Food Preservation; Food Storage; Guaiacol; Kinetics; Odorants; Oleic Acid; Particle Size; Plant Extracts; Powders; Stearic Acids; Surface Properties; Temperature; Volatile Organic Compounds; Zingiber officinale | 2018 |
Protective effects of zingerone on oxidative stress and inflammation in cisplatin-induced rat nephrotoxicity.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Cisplatin; Creatinine; Glutathione; Guaiacol; Inflammation; Kidney; L-Lactate Dehydrogenase; Male; Malondialdehyde; Organ Size; Oxidative Stress; Protective Agents; Rats, Wistar; Serum Albumin; Tumor Necrosis Factor-alpha | 2018 |
Therapeutic efficacy of zingerone against vancomycin-induced oxidative stress, inflammation, apoptosis and aquaporin 1 permeability in rat kidney.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Aquaporin 1; Guaiacol; Inflammation; Kidney; Male; Methicillin-Resistant Staphylococcus aureus; Oxidative Stress; Permeability; Rats; Rats, Sprague-Dawley; Treatment Outcome; Vancomycin | 2018 |
Renal protective effects of zingerone in a mouse model of sepsis.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Disease Models, Animal; Glutathione Peroxidase; Guaiacol; Kidney; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Plant Extracts; Protective Agents; Sepsis; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Zingiber officinale | 2019 |
Zingerone Suppresses Tumor Development through Decreasing Cyclin D1 Expression and Inducing Mitotic Arrest.
Topics: Animals; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Cyclin D1; Guaiacol; Humans; M Phase Cell Cycle Checkpoints; Male; Mice; Mice, Inbred BALB C; Mitosis; Neoplasms, Experimental; Poly (ADP-Ribose) Polymerase-1 | 2018 |
Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines.
Topics: Carcinoma, Hepatocellular; Caspases; Cell Cycle; Cell Line, Tumor; DNA Damage; Guaiacol; Humans; Liver Neoplasms; Nanoparticles; Neoplasm Proteins | 2019 |
Chemopreventive efficacy zingerone (4-[4-hydroxy-3-methylphenyl] butan-2-one) in experimental colon carcinogenesis in Wistar rats.
Topics: 1,2-Dimethylhydrazine; Aberrant Crypt Foci; Animals; Anticarcinogenic Agents; Carcinogenesis; Colonic Neoplasms; Guaiacol; Male; NF-E2-Related Factor 2; Rats; Rats, Wistar | 2019 |
Isoeugenol, a More Attractive Male Lure for the Cue-Lure-Responsive Pest Fruit Fly Bactrocera curvipennis (Diptera: Tephritidae: Dacinae), and New Records of Species Responding to Zingerone in New Caledonia.
Topics: Animals; Asia; Butanones; Eugenol; Guaiacol; Insect Control; Male; New Caledonia; Pheromones; Tephritidae | 2019 |
Osteogenic potential of zingerone, a phenolic compound in mouse mesenchymal stem cells.
Topics: Animals; Bone Density Conservation Agents; Calcium; Cell Differentiation; Cell Line; Core Binding Factor Alpha 1 Subunit; Gene Expression Regulation; Guaiacol; Mesenchymal Stem Cells; Mice; MicroRNAs; Osteoblasts; Osteogenesis; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta1; Zingiber officinale | 2019 |
Modulatory Effect of Selected Dietary Phytochemicals on Delayed Rectifier K
Topics: Antineoplastic Agents, Phytogenic; Caffeic Acids; Cell Line, Tumor; Flavanones; Flavonoids; Gallic Acid; Guaiacol; Humans; Ion Transport; Male; Membrane Potentials; Patch-Clamp Techniques; PC-3 Cells; Phytochemicals; Potassium; Potassium Channels, Voltage-Gated | 2019 |
Protective effects of zingerone on cisplatin-induced nephrotoxicity in female rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Apoptosis; Autophagy; Blood Urea Nitrogen; Catalase; Cisplatin; Deoxyguanosine; DNA Damage; Female; Glutathione; Glutathione Peroxidase; Guaiacol; Inflammation; Interleukin-6; Kidney; Lipid Peroxidation; Male; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Rats; Superoxide Dismutase; Toxicity Tests; Tumor Necrosis Factor-alpha | 2019 |
Protective effect of Zingerone against mouse testicular damage induced by zinc oxide nanoparticles.
Topics: Animals; Epididymis; Germ Cells; Guaiacol; Male; Malondialdehyde; Mice; Nanoparticles; Oxidation-Reduction; Oxidative Stress; Spermatogenesis; Superoxide Dismutase; Testis; Zinc Oxide | 2019 |
Zingerone attenuates aortic banding-induced cardiac remodelling via activating the eNOS/Nrf2 pathway.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta; Cardiomegaly; Cells, Cultured; Fibrosis; Guaiacol; Heart Failure; Inflammation; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Myocytes, Cardiac; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Oxidative Stress; Phenylephrine; Rats; Signal Transduction; Ventricular Remodeling | 2019 |
Modulatory effect of zingerone against STZ-nicotinamide induced type-2 diabetes mellitus in rats.
Topics: Animals; Antibiotics, Antineoplastic; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Guaiacol; Lipid Peroxidation; Lipids; Niacinamide; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Vitamin B Complex | 2021 |
The effects of zingerone against vancomycin-induced lung, liver, kidney and testis toxicity in rats: The behavior of some metabolic enzymes.
Topics: Animals; Enzymes; Guaiacol; Kidney; Liver; Lung; Male; Rats; Testis; Vancomycin | 2019 |
A Zingerone Analog, Acetyl Zingerone, Bolsters Matrisome Synthesis, Inhibits Matrix Metallopeptidases, and Represses IL-17A Target Gene Expression.
Topics: Cell Differentiation; Epidermis; Extracellular Matrix; Gene Expression Profiling; Gene Expression Regulation; Guaiacol; Humans; Interleukin-17; Matrix Metalloproteinase 12; Matrix Metalloproteinase 3; Oligonucleotide Array Sequence Analysis; Skin Aging; Tissue Culture Techniques | 2020 |
Zingerone induced caspase-dependent apoptosis in MCF-7 cells and prevents 7,12-dimethylbenz(a)anthracene-induced mammary carcinogenesis in experimental rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; Biotransformation; Blotting, Western; Carcinogens; Caspases; Guaiacol; Humans; Lipid Peroxidation; Mammary Neoplasms, Experimental; MCF-7 Cells; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2019 |
Modulatory effect of zingerone against cisplatin or γ-irradiation induced hepatotoxicity by molecular targeting regulation.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Cisplatin; Cytochrome P-450 CYP2E1; Gamma Rays; Gene Expression; Guaiacol; Inflammation Mediators; Liver; Male; MAP Kinase Signaling System; Molecular Targeted Therapy; Protective Agents; Radiation-Protective Agents; Rats | 2019 |
Acetyl zingerone: An efficacious multifunctional ingredient for continued protection against ongoing DNA damage in melanocytes after sun exposure ends.
Topics: Animals; Cells, Cultured; DNA Damage; Environmental Exposure; Guaiacol; Melanocytes; Mice; Mice, Inbred C57BL; Pyrimidine Dimers; Sunlight | 2020 |
Protective effects of zingerone derivate on ionizing radiation-induced intestinal injury.
Topics: Animals; Apoptosis; DNA Damage; Dose-Response Relationship, Radiation; Guaiacol; Intestines; Male; Mice, Inbred C57BL; Radiation-Protective Agents; Radiation, Ionizing; Survival Analysis | 2019 |
A ginger derivative, zingerone-a phenolic compound-induces ROS-mediated apoptosis in colon cancer cells (HCT-116).
Topics: Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Proliferation; Cell Survival; Colonic Neoplasms; DNA Damage; Guaiacol; HCT116 Cells; Humans; Lipid Peroxidation; Membrane Potential, Mitochondrial; Oxidative Stress; Plant Extracts; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Zingiber officinale | 2019 |
Systematic Modification of Zingerone Reveals Structural Requirements for Attraction of Jarvis's Fruit Fly.
Topics: Animals; Chemotactic Factors; Guaiacol; Male; Tephritidae; Vapor Pressure; Volatilization | 2019 |
Zingerone Promotes Osteoblast Differentiation Via MiR-200c-3p/smad7 Regulatory Axis in Human Bone Mesenchymal Stem Cells.
Topics: Alkaline Phosphatase; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Guaiacol; Humans; Mesenchymal Stem Cells; MicroRNAs; Osteoblasts; Osteocalcin; Osteogenesis; Smad7 Protein; Sp7 Transcription Factor | 2020 |
Zingerone ameliorates oxidative stress and inflammation in bleomycin-induced pulmonary fibrosis: modulation of the expression of TGF-β1 and iNOS.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bleomycin; Disease Models, Animal; Guaiacol; Inflammation Mediators; Lipid Peroxidation; Lung; Nitric Oxide Synthase Type II; Oxidative Stress; Pneumonia; Pulmonary Fibrosis; Rats, Wistar; Signal Transduction; Transforming Growth Factor beta1 | 2020 |
Otoprotective Effects of Zingerone on Cisplatin-Induced Ototoxicity.
Topics: Animals; Auditory Threshold; Cisplatin; Cochlea; Evoked Potentials, Auditory, Brain Stem; Female; Gene Expression Regulation; Guaiacol; Ototoxicity; Protective Agents; Rats, Sprague-Dawley; RNA, Messenger | 2020 |
Neonatal zingerone protects against the development of high-fructose diet-induced metabolic syndrome in adult Sprague-Dawley rats.
Topics: Animals; Animals, Newborn; Drug Evaluation, Preclinical; Female; Fructose; Guaiacol; Male; Metabolic Syndrome; Phytotherapy; Plant Extracts; Protective Agents; Rats, Sprague-Dawley; Sweetening Agents; Zingiber officinale | 2021 |
Comparative Trap Catches of Male Bactrocera, Dacus, and Zeugodacus Fruit Flies (Diptera: Tephritidae) With Four Floral Phenylbutanoid Lures (Anisyl Acetone, Cue-Lure, Raspberry Ketone, and Zingerone) in Queensland, Australia.
Topics: Acetone; Animals; Australia; Butanones; Guaiacol; Insect Control; Male; Pheromones; Queensland; Tephritidae | 2020 |
Zingerone prevents lead-induced toxicity in liver and kidney tissues by regulating the oxidative damage in Wistar rats.
Topics: Animals; Guaiacol; Kidney; Lead; Liver; Oxidative Stress; Rats; Rats, Wistar | 2021 |
Zingerone in the Flower of
Topics: Animals; Australia; Behavior, Animal; Female; Flowers; Gas Chromatography-Mass Spectrometry; Guaiacol; Male; Passiflora; Pheromones; Tephritidae | 2020 |
Zingerone protects liver and kidney tissues by preventing oxidative stress, inflammation, and apoptosis in methotrexate-treated rats.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Guaiacol; Inflammation; Kidney; Liver; Methotrexate; Oxidative Stress; Proto-Oncogene Proteins c-bcl-2; Rats | 2022 |
Zingerone attenuates vancomycin-induced hepatotoxicity in rats through regulation of oxidative stress, inflammation and apoptosis.
Topics: Animals; Apoptosis; Blotting, Western; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Guaiacol; Inflammation; Interleukin-1beta; Lipid Peroxidation; Liver; Male; NF-kappa B; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vancomycin | 2020 |
Zingerone suppresses cell proliferation via inducing cellular apoptosis and inhibition of the PI3K/AKT/mTOR signaling pathway in human prostate cancer PC-3 cells.
Topics: Apoptosis; Cell Proliferation; Guaiacol; Humans; Male; PC-3 Cells; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases | 2021 |
Male-lure type, lure dosage, and fly age at feeding all influence male mating success in Jarvis' fruit fly.
Topics: Age Factors; Animals; Butanones; Feeding Behavior; Female; Guaiacol; Male; Sexual Behavior, Animal; Tephritidae | 2020 |
Exploring the Therapeutic Efficacy of Zingerone Nanoparticles in Treating Biofilm-Associated Pyelonephritis Caused by Pseudomonas aeruginosa in the Murine Model.
Topics: Animals; Biofilms; Disease Models, Animal; Guaiacol; HEK293 Cells; Humans; Inflammation; Malondialdehyde; Mice; Microscopy, Electron, Scanning; Nanoparticles; Peroxidase; Phagocytosis; Pseudomonas aeruginosa; Pseudomonas Infections; Pyelonephritis; Stem Cells; Tetrazolium Salts; Thiazoles | 2020 |
Eugenol and Other Vanilloids Hamper Caenorhabditis elegans Response to Noxious Heat.
Topics: Analgesics; Animals; Avoidance Learning; Benzaldehydes; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Capsaicin; Eugenol; Guaiacol; Hot Temperature; Molecular Structure; Nerve Tissue Proteins; Nociception; Quantitative Structure-Activity Relationship; TRPV Cation Channels | 2021 |
Zingerone [4-(3-Methoxy-4-hydroxyphenyl)-butan-2] Attenuates Lipopolysaccharide-Induced Inflammation and Protects Rats from Sepsis Associated Multi Organ Damage.
Topics: Animals; Biomarkers; Cytokines; Guaiacol; Inflammation; Lipopolysaccharides; Male; Multiple Organ Failure; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Sepsis | 2020 |
Design, synthesis, molecular docking, anti-quorum sensing, and anti-biofilm activity of pyochelin-zingerone conjugate.
Topics: Anti-Bacterial Agents; Biofilms; Drug Design; Drug Resistance, Bacterial; Guaiacol; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Phenols; Pseudomonas aeruginosa; Quorum Sensing; Thiazoles | 2021 |
Zingerone improves the immune responses in an animal model of breast cancer.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Guaiacol; Immunity; Mice; Mice, Inbred BALB C; Zingiber officinale | 2021 |
Efficient Biosynthesis of Raspberry Ketone by Engineered
Topics: Butanones; Escherichia coli; Glucose 1-Dehydrogenase; Guaiacol | 2021 |
Improvement of Oral Bioavailability and Anti-Tumor Effect of Zingerone Self-Microemulsion Drug Delivery System.
Topics: Administration, Oral; Biological Availability; Drug Delivery Systems; Emulsions; Guaiacol; Particle Size; Solubility | 2021 |
The protective role of Zingerone in a murine asthma model via activation of the AMPK/Nrf2/HO-1 pathway.
Topics: AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Asthma; Disease Models, Animal; Guaiacol; Heme Oxygenase-1; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; Phytotherapy; Random Allocation; Signal Transduction; Specific Pathogen-Free Organisms | 2021 |
Synergistic Effect of Biogenics Derived from Potential Probiotics Together with Zingerone Against Biofilm Formation by Pseudomonas aeruginosa PAO1.
Topics: Anti-Infective Agents; Biofilms; Biological Products; Guaiacol; Probiotics; Pseudomonas aeruginosa | 2021 |
Zingerone (4-(four-hydroxy-3-methylphenyl) butane-two-1) modulates adjuvant-induced rheumatoid arthritis by regulating inflammatory cytokines and antioxidants.
Topics: Animals; Antioxidants; Arthritis, Rheumatoid; Butanes; Cytokines; Guaiacol; Rats; Rats, Wistar | 2021 |
Protective effects of zingerone on high cholesterol diet-induced atherosclerosis through lipid regulatory signaling pathway.
Topics: Animals; Atherosclerosis; Cholesterol, Dietary; Gene Expression Regulation; Guaiacol; Lipid Metabolism; Lipid Peroxidation; Male; Rats; Rats, Wistar; Signal Transduction | 2021 |
Improved oral bioavailability, cellular uptake, and cytotoxic activity of zingerone via nano-micelles drug delivery system.
Topics: Biological Availability; Drug Carriers; Drug Delivery Systems; Drug Liberation; Guaiacol; Micelles; Nanoparticle Drug Delivery System; Polyethylene Glycols | 2021 |
Development of edible Thai rice film fortified with ginger extract using microwave-assisted extraction for oral antimicrobial properties.
Topics: Catechols; Drug Resistance, Bacterial; Edible Films; Fatty Alcohols; Guaiacol; Microwaves; Oryza; Plant Extracts; Solid Phase Extraction; Streptococcus mutans; Thailand; Zingiber officinale | 2021 |
Tetrahexyldecyl Ascorbate (THDC) Degrades Rapidly under Oxidative Stress but Can Be Stabilized by Acetyl Zingerone to Enhance Collagen Production and Antioxidant Effects.
Topics: Antioxidants; Ascorbic Acid; Cell Line; Collagen; Fibroblasts; Guaiacol; Humans; Oxidative Stress | 2021 |
Investigating the Efficacy of Zingerone on Mesothelioma and the Role of TRPV1 in This Effect.
Topics: Capsaicin; Guaiacol; Humans; Mesothelioma; TRPV Cation Channels | 2022 |
Zingerone suppresses proliferation, invasion, and migration of hepatocellular carcinoma cells by the inhibition of MTDH-mediated PI3K/Akt pathway.
Topics: Animals; Carcinoma, Hepatocellular; Cell Adhesion Molecules; Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Guaiacol; Humans; Liver Neoplasms; Membrane Proteins; Mice; Mice, Nude; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA-Binding Proteins; Signal Transduction | 2022 |
Zingerone Inhibits the Neutrophil Extracellular Trap Formation and Protects against Sepsis via Nrf2-Mediated ROS Inhibition.
Topics: Animals; Blood Donors; Cells, Cultured; Cytokines; Disease Models, Animal; Extracellular Traps; Guaiacol; Humans; Male; Mice; Mice, Inbred C57BL; Neutrophils; NF-E2-Related Factor 2; Phagocytosis; Protective Agents; Reactive Oxygen Species; Sepsis; Signal Transduction; Treatment Outcome | 2022 |
Short-term treatment with zingerone ameliorates dextran sulfate sodium-induced mouse experimental colitis.
Topics: Animals; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Guaiacol; Mice; Mice, Inbred C57BL; PPAR gamma | 2022 |
Zingerone Modulates Neuronal Voltage-Gated Na
Topics: Action Potentials; Guaiacol; Humans; Ion Transport; Neurons; Pituitary Neoplasms; Sodium | 2022 |
Zingerone attenuates zearalenone-induced steroidogenesis impairment and apoptosis in TM3 Leydig cell line.
Topics: Apoptosis; Guaiacol; Humans; Leydig Cells; Male; Phosphatidylinositol 3-Kinases; Zearalenone | 2022 |
Zingerone ameliorates non-alcoholic fatty liver disease in rats by activating AMPK.
Topics: AMP-Activated Protein Kinases; Animals; Guaiacol; NF-E2-Related Factor 2; NF-kappa B; Non-alcoholic Fatty Liver Disease; Rats | 2022 |
Neonatal administration of zingerone prevents the subsequent development of high dietary fructose-induced early features of nephropathy in rats.
Topics: Animals; Diet; Female; Fructose; Guaiacol; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Water | 2022 |
Combinatorial Therapeutic Strategy of Biogenics Derived from Lactobacillus fermentum PUM and Zingerone Against Pseudomonas aeruginosa PAO1-Induced Surgical Site Infection: an Experimental Study.
Topics: Anti-Bacterial Agents; Biofilms; Guaiacol; Humans; Limosilactobacillus fermentum; Pseudomonas aeruginosa; Pseudomonas Infections; Surgical Wound Infection | 2022 |
Zingerone stimulates osteoblast differentiation by increasing Smad1/5/9-mediated HO-1 expression in MC3T3-E1 cells and primary mouse calvarial cells.
Topics: Animals; Bone Morphogenetic Protein 2; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; Guaiacol; Heme Oxygenase-1; Mice; Osteoblasts; Osteocalcin; Osteogenesis; Protein Phosphatase 2; Smad1 Protein; Transcription Factors | 2022 |
Protective Effects of Zingerone Against Depression-Like Behavior and Biochemical Changes in Chronic Stressed Rats: Antioxidant Effects.
Topics: Animals; Antioxidants; Depression; Female; Guaiacol; Lipid Peroxidation; Oxidative Stress; Rats; Rats, Wistar; Stress, Psychological; Superoxide Dismutase | 2022 |
The protective role of exogenous Ghrelin versus its combination with Zingerone on experimentally induced gastric ischemic-reperfusion in adult male albino rats.
Topics: Animals; Gastric Mucosa; Ghrelin; Guaiacol; Ischemia; Male; Rats; Rats, Wistar; Reperfusion Injury; Stomach | 2022 |
The anti-oxidative potential of ginger extract and its constituent on meat protein isolate under induced Fenton oxidation.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Catechols; Fatty Alcohols; Guaiacol; Hydrogen Peroxide; Kaempferols; Meat Proteins; Phenols; Plant Extracts; Protein Carbonylation; Quercetin; Rutin; Sheep; Thiobarbituric Acid Reactive Substances; Zingiber officinale | 2022 |
Sustainable Electropolymerization of Zingerone and Its C2 Symmetric Dimer for Amperometric Biosensor Films.
Topics: Ascorbic Acid; Glutamic Acid; Guaiacol; Polymers | 2023 |
Acetyl zingerone ameliorates osteoarthritis by inhibiting chondrocyte programmed cell death.
Topics: Animals; Apoptosis; Chondrocytes; Disease Models, Animal; Ferroptosis; Guaiacol; Mice | 2023 |