zinc coproporphyrin iii has been researched along with rifampin in 7 studies
| Studies (zinc coproporphyrin iii) | Trials (zinc coproporphyrin iii) | Recent Studies (post-2010) (zinc coproporphyrin iii) | Studies (rifampin) | Trials (rifampin) | Recent Studies (post-2010) (rifampin) |
|---|---|---|---|---|---|
| 119 | 6 | 43 | 20,468 | 1,499 | 6,552 |
| Protein | Taxonomy | zinc coproporphyrin iii (IC50) | rifampin (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 2.949 | |
| Caspase-1 | Homo sapiens (human) | 8.319 | |
| Alpha-synuclein | Homo sapiens (human) | 7.1 | |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | Mycobacterium tuberculosis H37Rv | 0.03 | |
| DNA-directed RNA polymerase subunit beta | Mycobacterium tuberculosis H37Rv | 0.01 | |
| Solute carrier organic anion transporter family member 1B3 | Homo sapiens (human) | 1.5 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Bednarczyk, D; Boiselle, C | 1 |
| Chen, W; Cheng, Y; Dai, J; Freeden, C; Humphreys, WG; Lai, Y; Liu, T; Marathe, P; Shen, H; Zhang, Y | 1 |
| Cheng, Y; Dai, J; Date, O; Gaud, N; Holenarsipur, VK; Humphreys, WG; Lai, Y; Langish, R; Mandlekar, S; Marathe, P; Murugesan, S; Rajanna, P; Selvam, S; Shen, H; Shipkova, P | 1 |
| Burrrell, R; Easter, J; Kadiyala, P; Kandoussi, H; Lai, Y; Langish, R; Marathe, P; Mariannino, T; Paterson, P; Pillutla, R; Santockyte, R; Shah, K; Shen, H; Shipkova, P; Zeng, J; Zhang, Y | 1 |
| Christopher, L; Garimella, T; Garonzik, S; Gong, J; Humphreys, WG; Kandoussi, H; Lai, Y; Perera, V; Shen, H | 1 |
| Fancher, RM; Gan, J; Gu, X; Hong, Y; Lai, Y; Shen, H; Sinz, M; Tian, Y; Wang, L | 1 |
| Chen, C; Chen, SJ; Chen, XQ; Fancher, RM; Puszczalo, PD; Shen, H; Shuster, DJ; Sinz, M; Yang, Z; Zhang, Y | 1 |
1 trial(s) available for zinc coproporphyrin iii and rifampin
| Article | Year |
|---|---|
Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition.
Topics: Adult; Biomarkers; Coproporphyrins; Drug Interactions; Humans; Male; Middle Aged; Organic Anion Transporters; Rifampin; Rosuvastatin Calcium; Young Adult | 2016 |
6 other study(ies) available for zinc coproporphyrin iii and rifampin
| Article | Year |
|---|---|
Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.
Topics: Animals; Area Under Curve; Biological Transport; Biomarkers; CHO Cells; Coproporphyrins; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Interactions; HEK293 Cells; Hepatocytes; Humans; Liver; Liver-Specific Organic Anion Transporter 1; Mass Spectrometry; Mutation; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rifampin; Serum Albumin, Bovine; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2016 |
Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species.
Topics: Animals; Area Under Curve; Coproporphyrins; Cyclosporine; HEK293 Cells; Hepatocytes; Humans; Liver-Specific Organic Anion Transporter 1; Macaca fascicularis; Mice; Mice, Knockout; Organic Anion Transporters; Rifampin; Rosuvastatin Calcium | 2016 |
UHPLC-MS/MS bioanalysis of human plasma coproporphyrins as potential biomarkers for organic anion-transporting polypeptide-mediated drug interactions.
Topics: Biomarkers, Pharmacological; Chromatography, High Pressure Liquid; Coproporphyrins; Drug Design; Drug Interactions; Humans; Organic Anion Transporters; Rifampin; Rosuvastatin Calcium; Tandem Mass Spectrometry | 2018 |
Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.
Topics: Adult; Biological Transport; Biomarkers; Coproporphyrins; Drug Interactions; Genotype; Humans; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Organic Anion Transporters; Rifampin; Solute Carrier Organic Anion Transporter Family Member 1B3; Young Adult | 2018 |
Absorption and Disposition of Coproporphyrin I (CPI) in Cynomolgus Monkeys and Mice: Pharmacokinetic Evidence to Support the Use of CPI to Inform the Potential for Organic Anion-Transporting Polypeptide Inhibition.
Topics: Administration, Intravenous; Administration, Oral; Animals; Area Under Curve; Biological Availability; Biomarkers; Coproporphyrins; Cyclosporine; Drug Evaluation, Preclinical; Drug Interactions; Half-Life; Intestinal Absorption; Kidney; Liver; Liver-Specific Organic Anion Transporter 1; Macaca fascicularis; Male; Mice; Rifampin; Tissue Distribution | 2020 |
Absence of OATP1B (Organic Anion-Transporting Polypeptide) Induction by Rifampin in Cynomolgus Monkeys: Determination Using the Endogenous OATP1B Marker Coproporphyrin and Tissue Gene Expression.
Topics: Animals; Biomarkers; Coproporphyrins; Female; Gene Expression; Hydroxycholesterols; Intestine, Small; Kidney; Liver; Macaca fascicularis; Male; Rifampin; Solute Carrier Organic Anion Transporter Family Member 1B3 | 2020 |