Page last updated: 2024-08-24

zileuton and ys 121

zileuton has been researched along with ys 121 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Greiner, C; Koeberle, A; Schubert-Zsilavecz, M; Werz, O; Wurglics, M; Zettl, H1
Buscató, E; Deckmann, K; Geisslinger, G; Grösch, S; Proschak, E; Rörsch, F; Schneider, G; Schubert-Zsilavecz, M1
Barz, D; Dehm, F; Hanke, T; Kaiser, A; Kunze, J; Lämmerhofer, M; Liening, S; Maczewsky, J; Pillong, M; Popella, SD; Sautebin, L; Schneider, G; Schubert-Zsilavecz, M; Weinigel, C; Werz, O; Wurglics, M1

Other Studies

3 other study(ies) available for zileuton and ys 121

ArticleYear
Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase.
    Journal of medicinal chemistry, 2008, Dec-25, Volume: 51, Issue:24

    Topics: Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Cyclooxygenase 1; Cyclooxygenase 2; Drug Design; Enzyme Activation; Enzyme Inhibitors; Humans; Inflammation; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Models, Chemical; Prostaglandin-E Synthases; Pyrimidines

2008
Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1).
    Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8

    Topics: Animals; Biological Availability; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; HeLa Cells; Humans; Intramolecular Oxidoreductases; Mice; Microsomes; Prostaglandin-E Synthases; Quinazolinones; Structure-Activity Relationship

2012
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
    Journal of medicinal chemistry, 2013, Nov-27, Volume: 56, Issue:22

    Topics: Animals; Arachidonate 5-Lipoxygenase; Binding Sites; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Male; Mice; Microsomes; Models, Molecular; Peritonitis; Prostaglandin-E Synthases; Protein Conformation; Pyrimidines; Structure-Activity Relationship; Thiazoles; Zymosan

2013