zileuton has been researched along with thromboxane b2 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Crawley, GC; Foster, SJ; McMillan, RM; Spruce, KE; Walker, ER | 1 |
| Cohn, J; Dworski, R; Fish, JE; Kane, GC; Kim, CJ; Murray, JJ; Peters, SP; Pollice, M; Sheller, J; Tollino, M | 1 |
| Awni, WM; Braeckman, RA; Cavanaugh, JH; Dubé, LM; Granneman, GR; Linnen, PJ; Locke, CS | 1 |
| Harada, K; Hibi, S; Kawahara, T; Kobayashi, N; Miyamoto, K; Numata, H; Okamoto, Y; Shinoda, M; Tagami, K; Yamatsu, I | 1 |
| Harada, K; Inoue, T; Nagakura, N; Oketani, K | 1 |
| Dev, A; Leong, AB; Wu, X | 1 |
| Altavilla, D; Arcoraci, V; Bitto, A; Galfo, F; Irrera, N; Macrì, A; Minutoli, L; Pallio, G; Pizzino, G; Squadrito, F; Squadrito, G | 1 |
2 trial(s) available for zileuton and thromboxane b2
| Article | Year |
|---|---|
Insights into IgE-mediated lung inflammation derived from a study employing a 5-lipoxygenase inhibitor.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cross-Over Studies; Dinoprost; Dinoprostone; Double-Blind Method; Eosinophils; Humans; Hydroxyurea; Leukotriene B4; Leukotriene E4; Leukotrienes; Lipoxygenase Inhibitors; Lung; Lung Injury; Placebos; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Proteins; Regression Analysis; Respiratory Hypersensitivity; Thromboxane B2 | 1995 |
The pharmacokinetic and pharmacodynamic interactions between the 5-lipoxygenase inhibitor zileuton and the cyclo-oxygenase inhibitor naproxen in human volunteers.
Topics: Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Digestive System; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Endoscopy; Humans; Hydroxyurea; Intestinal Mucosa; Leukotriene B4; Lipoxygenase Inhibitors; Male; Naproxen; Thromboxane B2 | 1995 |
5 other study(ies) available for zileuton and thromboxane b2
| Article | Year |
|---|---|
Pre-clinical pharmacology of ICI D2138, a potent orally-active non-redox inhibitor of 5-lipoxygenase.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hydroxyurea; Inflammation; Knee Joint; Leukotriene B4; Lipoxygenase Inhibitors; Macrophages; Male; Mice; Oxidation-Reduction; Pyrans; Quinolones; Rabbits; Rats; Thromboxane B2 | 1992 |
Structure-activity relationships of (E)-3-(1,4-benzoquinonyl)-2-[(3-pyridyl)-alkyl]-2-propenoic acid derivatives that inhibit both 5-lipoxygenase and thromboxane A2 synthetase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Blood Platelets; Cells, Cultured; Humans; Hydroxyurea; Leukotriene B4; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Methacrylates; Molecular Structure; Neutrophils; Pyridines; Rats; Structure-Activity Relationship; Thromboxane B2; Thromboxane-A Synthase | 1996 |
In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzothiazoles; Dinoprostone; Dose-Response Relationship, Drug; Eicosanoids; Humans; Hydroxyurea; Indomethacin; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mesalamine; Methacrylates; Neutrophils; Peritoneal Cavity; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Inbred F344; Sheep; Sulfasalazine; Thiazoles; Thromboxane B2; Thromboxane-A Synthase | 2001 |
Zileuton, a 5-lipoxygenase inhibitor, increases production of thromboxane A2 and platelet aggregation in patients with asthma.
Topics: Adult; Aged; Asthma; Female; Humans; Hydroxyurea; Lipoxygenase Inhibitors; Male; Middle Aged; Platelet Aggregation; Thromboxane A2; Thromboxane B2 | 2003 |
Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Body Weight; Catechin; CD3 Complex; Celecoxib; Colitis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Combinations; Eating; Gene Expression Regulation; Hydroxyurea; Leukotriene B4; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Thromboxane B2; Tumor Necrosis Factor-alpha | 2016 |